ZA986203B - Preparation process for aminated derivatives of alkyloxyfuranone, compounds originating form this process and use of these compounds. - Google Patents

Preparation process for aminated derivatives of alkyloxyfuranone, compounds originating form this process and use of these compounds.

Info

Publication number
ZA986203B
ZA986203B ZA9806203A ZA986203A ZA986203B ZA 986203 B ZA986203 B ZA 986203B ZA 9806203 A ZA9806203 A ZA 9806203A ZA 986203 A ZA986203 A ZA 986203A ZA 986203 B ZA986203 B ZA 986203B
Authority
ZA
South Africa
Prior art keywords
compounds
alkyloxyfuranone
preparation process
originating form
aminated derivatives
Prior art date
Application number
ZA9806203A
Other languages
English (en)
Inventor
Raphael Bouchet
Francis Brion
Colette Colladant
Jacques Lagouardat
Original Assignee
Hoechst Marion Roussel Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Inc filed Critical Hoechst Marion Roussel Inc
Publication of ZA986203B publication Critical patent/ZA986203B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • C07D307/33Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00Separation of optically-active compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/26Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D307/30Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/32Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60Two oxygen atoms, e.g. succinic anhydride
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1024Tetrapeptides with the first amino acid being heterocyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Furan Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ZA9806203A 1997-07-15 1998-07-13 Preparation process for aminated derivatives of alkyloxyfuranone, compounds originating form this process and use of these compounds. ZA986203B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR9708932A FR2766188B1 (fr) 1997-07-15 1997-07-15 Nouveau procede de preparation de derives amines d'alkyloxy furanone, composes issus de ce procede et utilisation de ces composes

Publications (1)

Publication Number Publication Date
ZA986203B true ZA986203B (en) 1999-08-18

Family

ID=9509210

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA9806203A ZA986203B (en) 1997-07-15 1998-07-13 Preparation process for aminated derivatives of alkyloxyfuranone, compounds originating form this process and use of these compounds.

Country Status (34)

Country Link
US (1) US6235899B1 (hu)
EP (1) EP0998470B1 (hu)
JP (1) JP4450987B2 (hu)
KR (1) KR100519691B1 (hu)
CN (1) CN100363355C (hu)
AP (1) AP1071A (hu)
AR (1) AR015924A1 (hu)
AT (1) ATE239713T1 (hu)
AU (1) AU744272B2 (hu)
BG (1) BG64050B1 (hu)
BR (1) BR9810896A (hu)
CA (1) CA2296742C (hu)
CZ (1) CZ295312B6 (hu)
DE (1) DE69814395T2 (hu)
DK (1) DK0998470T3 (hu)
EA (1) EA002883B1 (hu)
EE (1) EE03873B1 (hu)
ES (1) ES2197489T3 (hu)
FR (1) FR2766188B1 (hu)
HR (1) HRP20000027B1 (hu)
HU (1) HU230148B1 (hu)
ID (1) ID23784A (hu)
IL (1) IL134031A (hu)
ME (1) ME01708B (hu)
NO (1) NO324508B1 (hu)
NZ (1) NZ502338A (hu)
PL (1) PL200820B1 (hu)
PT (1) PT998470E (hu)
RS (1) RS49832B (hu)
SK (1) SK284168B6 (hu)
TR (1) TR200000117T2 (hu)
UA (1) UA66364C2 (hu)
WO (1) WO1999003852A1 (hu)
ZA (1) ZA986203B (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7053056B2 (en) 1998-07-02 2006-05-30 Idun Pharmaceuticals, Inc. C-terminal modified oxamyl dipeptides as inhibitors of the ICE/ced-3 family of cysteine proteases
DE60142470D1 (de) * 2000-04-24 2010-08-12 Vertex Pharma Verfahren und zwischenprodukte zur herstellung von substituierten asparaginsäure-acetalen
PE20011350A1 (es) 2000-05-19 2002-01-15 Vertex Pharma PROFARMACO DE UN INHIBIDOR DE ENZIMA CONVERTIDORA DE INTERLEUCINA-1ß (ICE)
JP2003327568A (ja) * 2000-09-20 2003-11-19 Kanegafuchi Chem Ind Co Ltd 光学活性β−アミノ酸誘導体の製造方法
JPWO2002055478A1 (ja) * 2001-01-16 2004-05-13 鐘淵化学工業株式会社 光学活性アミノラクトン誘導体の製造法およびその中間体
AU2005219861B2 (en) 2004-02-27 2011-08-11 Vertex Pharmaceuticals Incorporated Caspase inhibitors and uses thereof
PT1725548E (pt) * 2004-03-12 2015-04-16 Vertex Pharma Processo e intermediários para a preparação de inibidores de caspase de acetal de ácido aspártico

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204261B1 (en) * 1995-12-20 2001-03-20 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β Converting enzyme inhibitors
US5716929A (en) * 1994-06-17 1998-02-10 Vertex Pharmaceuticals, Inc. Inhibitors of interleukin-1β converting enzyme

Also Published As

Publication number Publication date
KR20010021834A (ko) 2001-03-15
AR015924A1 (es) 2001-05-30
RS49832B (sr) 2008-08-07
DE69814395T2 (de) 2003-12-11
BG64050B1 (bg) 2003-11-28
NO20000182L (no) 2000-03-07
AU8633398A (en) 1999-02-10
CZ295312B6 (cs) 2005-07-13
UA66364C2 (uk) 2004-05-17
AU744272B2 (en) 2002-02-21
NZ502338A (en) 2001-09-28
YU1500A (sh) 2002-10-18
CN1269795A (zh) 2000-10-11
AP1071A (en) 2002-05-20
EP0998470B1 (fr) 2003-05-07
CA2296742C (fr) 2009-12-08
PL200820B1 (pl) 2009-02-27
US6235899B1 (en) 2001-05-22
EP0998470A1 (fr) 2000-05-10
EE200000024A (et) 2000-10-16
HU230148B1 (hu) 2015-09-28
HUP0003857A3 (en) 2002-08-28
EA200000127A1 (ru) 2000-08-28
FR2766188B1 (fr) 2000-02-11
HRP20000027B1 (en) 2006-07-31
CN100363355C (zh) 2008-01-23
AP2000001732A0 (en) 2000-03-31
EE03873B1 (et) 2002-10-15
NO324508B1 (no) 2007-11-05
WO1999003852A1 (fr) 1999-01-28
CA2296742A1 (fr) 1999-01-28
PT998470E (pt) 2003-09-30
CZ200065A3 (cs) 2000-07-12
BG104073A (en) 2001-05-31
KR100519691B1 (ko) 2005-10-13
JP4450987B2 (ja) 2010-04-14
HUP0003857A2 (hu) 2001-04-28
BR9810896A (pt) 2000-09-26
DE69814395D1 (de) 2003-06-12
JP2001510191A (ja) 2001-07-31
SK284168B6 (sk) 2004-10-05
NO20000182D0 (no) 2000-01-14
ME01708B (me) 2008-08-07
TR200000117T2 (tr) 2000-07-21
IL134031A (en) 2004-06-01
IL134031A0 (en) 2001-04-30
EA002883B1 (ru) 2002-10-31
ATE239713T1 (de) 2003-05-15
PL338035A1 (en) 2000-09-25
HRP20000027A2 (en) 2000-10-31
DK0998470T3 (da) 2003-09-01
ES2197489T3 (es) 2004-01-01
SK302000A3 (en) 2000-11-07
ID23784A (id) 2000-05-11
FR2766188A1 (fr) 1999-01-22

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