IL132614A0 - Human toll-like receptor proteins related reagents and methods - Google Patents

Human toll-like receptor proteins related reagents and methods

Info

Publication number
IL132614A0
IL132614A0 IL13261498A IL13261498A IL132614A0 IL 132614 A0 IL132614 A0 IL 132614A0 IL 13261498 A IL13261498 A IL 13261498A IL 13261498 A IL13261498 A IL 13261498A IL 132614 A0 IL132614 A0 IL 132614A0
Authority
IL
Israel
Prior art keywords
methods
receptor proteins
proteins related
related reagents
human toll
Prior art date
Application number
IL13261498A
Other languages
English (en)
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27366459&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL132614(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Schering Corp filed Critical Schering Corp
Publication of IL132614A0 publication Critical patent/IL132614A0/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
IL13261498A 1997-05-07 1998-05-07 Human toll-like receptor proteins related reagents and methods IL132614A0 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US4429397P 1997-05-07 1997-05-07
US7221298P 1998-01-22 1998-01-22
US7694798P 1998-03-05 1998-03-05
PCT/US1998/008979 WO1998050547A2 (en) 1997-05-07 1998-05-07 Human toll-like receptor proteins, related reagents and methods

Publications (1)

Publication Number Publication Date
IL132614A0 true IL132614A0 (en) 2001-03-19

Family

ID=27366459

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13261498A IL132614A0 (en) 1997-05-07 1998-05-07 Human toll-like receptor proteins related reagents and methods

Country Status (20)

Country Link
EP (4) EP1988166A1 (de)
JP (4) JP2002514083A (de)
KR (1) KR100388860B1 (de)
CN (4) CN1800214A (de)
AT (3) ATE348157T1 (de)
AU (1) AU740333B2 (de)
CA (1) CA2289912C (de)
CY (1) CY1109645T1 (de)
DE (3) DE69836630T2 (de)
DK (2) DK0980429T3 (de)
ES (3) ES2340210T3 (de)
HK (3) HK1022175A1 (de)
ID (1) ID28299A (de)
IL (1) IL132614A0 (de)
NO (1) NO995458D0 (de)
NZ (1) NZ338073A (de)
PL (1) PL336635A1 (de)
PT (1) PT1798288E (de)
SK (1) SK146599A3 (de)
WO (1) WO1998050547A2 (de)

Families Citing this family (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8212004B2 (en) 1999-03-02 2012-07-03 Human Genome Sciences, Inc. Neutrokine-alpha fusion proteins
US6812327B1 (en) 1996-10-25 2004-11-02 Human Genome Sciences, Inc. Neutrokine-alpha polypeptides
US7696327B1 (en) 1997-10-17 2010-04-13 Genentech, Inc. Antibodies to human Toll homologues
US20030032090A1 (en) 1997-05-07 2003-02-13 Schering Corporation, A New Jersey Corporation Human receptor proteins; related reagents and methods
ATE314471T1 (de) * 1997-10-17 2006-01-15 Genentech Inc Menschliche toll homologen
AU2003203679B2 (en) * 1997-10-17 2007-04-05 Genentech, Inc. Human toll homologues
JP2000128900A (ja) * 1998-10-26 2000-05-09 Japan Science & Technology Corp 新規トル様（Ｔｏｌｌ−ｌｉｋｅ）レセプター及びその遺伝子
US6303321B1 (en) 1999-02-11 2001-10-16 North Shore-Long Island Jewish Research Institute Methods for diagnosing sepsis
US6740487B1 (en) 1999-06-10 2004-05-25 University Of Iowa Research Foundation Variant TLR4 nucleic acid and uses thereof
WO2001032877A2 (en) * 1999-11-02 2001-05-10 Chiron Corporation CpG RECEPTOR (CpG-R) AND METHODS RELATING THERETO
GB9927332D0 (en) * 1999-11-18 2000-01-12 Leiv Eiriksson Nyfotek As Novel antibody and uses thereof
GB0001704D0 (en) * 2000-01-25 2000-03-15 Glaxo Group Ltd Protein
US20030083244A1 (en) * 2000-04-26 2003-05-01 Vernet Corine A.M. Novel proteins and nucleic acids encoding same
JP2003533996A (ja) * 2000-05-25 2003-11-18 シェーリング コーポレイション ヒトレセプタータンパク質、関連試薬および方法
DE60143798D1 (de) 2000-06-16 2011-02-17 Cambridge Antibody Tech Immunspezifisch bindende antikörper gegen blys
US7879328B2 (en) 2000-06-16 2011-02-01 Human Genome Sciences, Inc. Antibodies that immunospecifically bind to B lymphocyte stimulator
JP2002034565A (ja) * 2000-07-19 2002-02-05 Japan Science & Technology Corp 細菌ｄｎａを特異的に認識する受容体タンパク質
WO2002016411A2 (en) * 2000-08-18 2002-02-28 Human Genome Sciences, Inc. Binding polypeptides and methods based thereon
US7118872B2 (en) * 2000-08-18 2006-10-10 Dyax Corp. Binding polypeptides for B lymphocyte stimulator protein (BLyS)
ATE510850T1 (de) 2000-09-15 2011-06-15 Coley Pharm Gmbh Verfahren zum hochdurchsatzscreening von auf cpg basierenden immunagonisten und -antagonisten
US7220723B2 (en) 2001-05-15 2007-05-22 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
US7304034B2 (en) 2001-05-15 2007-12-04 The Feinstein Institute For Medical Research Use of HMGB fragments as anti-inflammatory agents
WO2003031573A2 (en) * 2001-10-05 2003-04-17 Coley Pharmaceutical Gmbh Toll-like receptor 3 signaling agonists and antagonists
DK1719511T3 (da) * 2001-11-16 2009-04-14 Coley Pharm Group Inc N-[4-(4-amino-2-ethyl-1H-imidazo[4,5-c]quinolin-1-yl)butyl]methansulfonamid, en farmaceutisk sammensætning omfattende samme, og anvendelse deraf
GB0127618D0 (en) * 2001-11-17 2002-01-09 Univ Nottingham "Composition and method for treatment of wounds"
JP2004016021A (ja) 2002-06-12 2004-01-22 Japan Science & Technology Corp 抗体および阻害剤並びにそれを用いた形質転換方法および形質転換キット
AU2003287316A1 (en) * 2002-12-11 2004-06-30 3M Innovative Properties Company Assays relating to toll-like receptor activity
WO2004094671A2 (en) * 2003-04-22 2004-11-04 Coley Pharmaceutical Gmbh Methods and products for identification and assessment of tlr ligands
US7696169B2 (en) 2003-06-06 2010-04-13 The Feinstein Institute For Medical Research Inhibitors of the interaction between HMGB polypeptides and toll-like receptor 2 as anti-inflammatory agents
CN1878793A (zh) 2003-09-11 2006-12-13 鉴定医疗有限公司 拮抗hmgb1的单克隆抗体
TW200514850A (en) * 2003-10-03 2005-05-01 Hitachi Chemical Co Ltd Method of evaluating risk for viral infection
TW200516153A (en) * 2003-10-03 2005-05-16 Hitachi Chemical Co Ltd Human toll-like receptor 3 gene polymorphism as marker for inherited factor of allergic disease and utilization of the same
US8871782B2 (en) 2003-10-03 2014-10-28 3M Innovative Properties Company Alkoxy substituted imidazoquinolines
US7202234B2 (en) 2003-10-24 2007-04-10 Eisai Co., Ltd. Compounds and methods for treating Toll-like receptor 2-related diseases and conditions
KR101130928B1 (ko) 2003-11-25 2012-04-12 쓰리엠 이노베이티브 프로퍼티즈 컴파니 치환된 이미다조 고리 시스템 및 방법
JP2008022701A (ja) * 2004-09-24 2008-02-07 Japan Science & Technology Agency 可溶型Ｔｏｌｌ様受容体４タンパク質
CA2587676A1 (en) 2004-11-19 2006-05-26 Institut Gustave Roussy Improved treatment of cancer by double-stranded rna
TWI487535B (zh) 2004-11-30 2015-06-11 Centocor Inc 類鐸受體３（ｔｏｌｌ ｌｉｋｅ ｒｅｃｅｐｔｏｒ３）拮抗劑，方法及用途
CA2597092A1 (en) 2005-02-04 2006-08-10 Coley Pharmaceutical Group, Inc. Aqueous gel formulations containing immune reponse modifiers
US7700728B2 (en) 2005-03-24 2010-04-20 Schering Corporation Use of chimeric receptors in a screening assay for identifying agonists and antagonists of cell receptors
US7498409B2 (en) 2005-03-24 2009-03-03 Schering Corporation Screening assay for TLR7, TLR8 and TLR9 agonists and antagonists
US9168286B2 (en) 2005-10-13 2015-10-27 Human Genome Sciences, Inc. Methods and compositions for use in treatment of patients with autoantibody positive disease
DK1945820T3 (da) 2005-10-27 2013-11-11 Janssen Biotech Inc Toll-lignende receptor-3-modulatorer, fremgangsmåder og anvendelser
TW200745158A (en) 2006-03-07 2007-12-16 Vaxinnate Corp Compositions that include hemagglutinin, methods of making and methods of use thereof
WO2007123765A2 (en) 2006-03-31 2007-11-01 Human Genome Sciences Inc. Neutrokine-alpha and neutrokine-alpha splice variant
CN101134046B (zh) * 2006-09-01 2011-10-05 中国医学科学院药物研究所 Tlr4和tlr9激动剂复方在抑制肿瘤转移中的应用
EP2155889A4 (de) * 2007-05-25 2010-06-16 Centocor Ortho Biotech Inc Toll-artige rezeptor-3-modulatoren und verwendungen dafür
CA2722589A1 (en) 2008-04-25 2009-10-29 Innate Pharma Improved tlr3 agonist compositions
EP2116602A1 (de) 2008-05-07 2009-11-11 Institut Gustave Roussy Kombinationsprodukte zur Behandlung von Krebs
EP2334703B1 (de) 2008-09-17 2015-07-08 Innate Pharma Zusammensetzungen und verfahren zum nachweis von tlr3
US9512196B2 (en) 2008-09-22 2016-12-06 Cedars-Sinai Medical Center Short-form human MD-2 as a negative regulator of toll-like receptor 4 signaling
EP2328911A4 (de) 2008-09-22 2012-03-14 Cedars Sinai Medical Center Kurzes menschliches md-2 als negativer regulator der toll-like-rezeptor-4-signalisierung
EP2451844B1 (de) 2009-07-10 2015-04-22 Innate Pharma Tlr3-binder
WO2011021524A1 (ja) * 2009-08-19 2011-02-24 国立大学法人名古屋大学 乳酸菌の付着性を誘導するペプチド及びその用途
EP2596009B1 (de) 2010-07-19 2017-08-23 Yeda Research and Development Co. Ltd. Peptide, basierend auf der transmembrandomäne eines "toll-like" rezeptors (tlr) für die behandlung einer tlr-vermittelten krankheit
WO2013054329A1 (en) * 2011-10-10 2013-04-18 Yeda Research And Development Co. Ltd. Toll-like receptor 4 (tlr-4) agonist peptides for modulating tlr-4 mediated immune response
US9814740B2 (en) 2010-12-21 2017-11-14 Duke University Methods and compositions combining immunotherapy with monocyte activation
US20140065154A1 (en) 2011-01-12 2014-03-06 Innate Pharma Tlr3 binding agents
US9353115B2 (en) 2011-06-01 2016-05-31 Janus Biotherapeutics, Inc. Immune system modulators
CN103717070A (zh) 2011-06-01 2014-04-09 贾纳斯生物治疗有限公司 新型免疫系统调节剂
AU2012318694B2 (en) 2011-10-04 2016-12-22 Janus Biotherapeutics, Inc. Novel imidazole quinoline-based immune system modulators
MX361773B (es) 2012-05-31 2018-12-17 Innate Pharma Agentes de ligación a tlr3.
US10017739B2 (en) 2012-09-06 2018-07-10 Duke University Methods of expanding and assessing B cells and using expanded B cells to treat disease
CN113502299B (zh) * 2021-07-20 2023-03-14 中国农业大学 一种抗金黄色葡萄球菌遗传修饰山羊生产方法

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3645090A (en) 1969-06-19 1972-02-29 Citizen Watch Co Ltd Day-date quick-adjuster for calender timepiece
US3940475A (en) 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4659678A (en) 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4859609A (en) 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists
US5789192A (en) 1992-12-10 1998-08-04 Schering Corporation Mammalian receptors for interleukin-10 (IL-10)
AU3514997A (en) * 1996-07-12 1998-02-09 Schering Corporation Mammalian tnf-alpha convertases
ES2267192T3 (es) * 1997-08-01 2007-03-01 Serono Genetics Institute S.A. Ests 5' para proteinas secretadas no especificas de tejido.
ATE314471T1 (de) * 1997-10-17 2006-01-15 Genentech Inc Menschliche toll homologen

Also Published As

Publication number Publication date
WO1998050547A2 (en) 1998-11-12
ID28299A (id) 2001-05-10
HK1022175A1 (en) 2000-07-28
HK1102720A1 (en) 2007-12-07
DK0980429T3 (da) 2007-04-10
WO1998050547A3 (en) 1999-03-11
EP1798288B1 (de) 2009-09-16
EP1798288A3 (de) 2007-09-12
NO995458L (no) 1999-11-08
HK1112018A1 (en) 2008-08-22
CY1109645T1 (el) 2012-05-23
PL336635A1 (en) 2000-07-03
EP1925666A1 (de) 2008-05-28
EP0980429A2 (de) 2000-02-23
NO995458D0 (no) 1999-11-08
ATE443139T1 (de) 2009-10-15
JP2009089713A (ja) 2009-04-30
PT1798288E (pt) 2009-12-23
CN1935840A (zh) 2007-03-28
DE69841170D1 (de) 2009-10-29
CN1225555C (zh) 2005-11-02
CN1800214A (zh) 2006-07-12
ATE348157T1 (de) 2007-01-15
NZ338073A (en) 2001-09-28
ES2331622T3 (es) 2010-01-11
EP0980429B1 (de) 2006-12-13
SK146599A3 (en) 2000-07-11
EP1988166A1 (de) 2008-11-05
CN101486759A (zh) 2009-07-22
KR100388860B1 (ko) 2003-06-25
DE69841514D1 (de) 2010-04-01
AU740333B2 (en) 2001-11-01
CA2289912C (en) 2011-07-26
CA2289912A1 (en) 1998-11-12
JP2005120106A (ja) 2005-05-12
CN1263555A (zh) 2000-08-16
DK1798288T3 (da) 2010-01-04
ES2279572T3 (es) 2007-08-16
JP2002514083A (ja) 2002-05-14
JP2006052232A (ja) 2006-02-23
ATE458053T1 (de) 2010-03-15
DE69836630T2 (de) 2007-10-11
EP1798288A2 (de) 2007-06-20
AU7175498A (en) 1998-11-27
EP1925666B1 (de) 2010-02-17
KR20010012323A (ko) 2001-02-15
ES2340210T3 (es) 2010-05-31
DE69836630D1 (de) 2007-01-25

Similar Documents

Publication Publication Date Title
HK1112018A1 (en) Human toll-like receptor proteins, related reagents and methods
HK1049862A1 (en) Mammalian cytokine receptor subunit proteins, related reagents and methods
WO1998031799A3 (en) Polynucleotides and polypeptides encoding receptors
AU2001294541A1 (en) Mammalian genes; related reagents and methods
EP1908837A3 (de) Menschliche Rezeptorproteine, zugehörige Reagenzien und Verfahren
CY1109093T1 (el) Πρωτεϊνες των υποδοχεων θηλαστικων, σχετικα αντιδραστηρια και σχετικες μεθοδοι
NO992916L (no) Fosfodiesterase 8A
WO1996021734A3 (en) P15 and tyrosinase melanoma antigens and their use in diagnostic and therapeutic methods
WO2001036467A3 (en) Mammalian receptor proteins; related reagents and methods
WO1999046379A3 (en) Human receptor proteins; related reagents and methods
AU1971295A (en) Humanized monoclonal antibodies against human interleukin-4
WO1999019480A3 (en) Human receptor proteins; related reagents and methods
WO1998041538A3 (en) Novel human cytokine/steroid receptor protein
BR9808747A (pt) Proteìnas receptoras humanas; reagentes relacionados e métodos