IL130334A0 - Pharmaceutical aminophosphonic acid derivatives - Google Patents

Pharmaceutical aminophosphonic acid derivatives

Info

Publication number
IL130334A0
IL130334A0 IL13033497A IL13033497A IL130334A0 IL 130334 A0 IL130334 A0 IL 130334A0 IL 13033497 A IL13033497 A IL 13033497A IL 13033497 A IL13033497 A IL 13033497A IL 130334 A0 IL130334 A0 IL 130334A0
Authority
IL
Israel
Prior art keywords
pharmaceutical
acid derivatives
aminophosphonic acid
aminophosphonic
derivatives
Prior art date
Application number
IL13033497A
Other languages
English (en)
Original Assignee
Symphar Sa
Smithkline Beecham Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Symphar Sa, Smithkline Beecham Plc filed Critical Symphar Sa
Publication of IL130334A0 publication Critical patent/IL130334A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/553Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
    • C07F9/576Six-membered rings
    • C07F9/58Pyridine rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
IL13033497A 1996-12-20 1997-12-17 Pharmaceutical aminophosphonic acid derivatives IL130334A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9626615.0A GB9626615D0 (en) 1996-12-20 1996-12-20 Novel compounds
PCT/EP1997/007161 WO1998028310A1 (en) 1996-12-20 1997-12-17 Pharmaceutical aminophosphonic acid derivatives

Publications (1)

Publication Number Publication Date
IL130334A0 true IL130334A0 (en) 2000-06-01

Family

ID=10804837

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13033497A IL130334A0 (en) 1996-12-20 1997-12-17 Pharmaceutical aminophosphonic acid derivatives

Country Status (31)

Country Link
US (2) US6303784B1 (no)
EP (1) EP0946572B1 (no)
JP (1) JP2001506667A (no)
KR (1) KR20000069609A (no)
CN (1) CN1105117C (no)
AP (1) AP9901546A0 (no)
AR (1) AR008541A1 (no)
AT (1) ATE255117T1 (no)
AU (1) AU5858898A (no)
BG (1) BG103574A (no)
BR (1) BR9714650A (no)
CA (1) CA2275696A1 (no)
CO (1) CO4930276A1 (no)
DE (1) DE69726449T2 (no)
DZ (1) DZ2377A1 (no)
EA (1) EA199900580A1 (no)
GB (1) GB9626615D0 (no)
HU (1) HUP0002171A3 (no)
ID (1) ID22053A (no)
IL (1) IL130334A0 (no)
MA (1) MA24427A1 (no)
NO (1) NO993001L (no)
NZ (1) NZ335884A (no)
OA (1) OA11068A (no)
PE (1) PE46799A1 (no)
PL (1) PL334189A1 (no)
SK (1) SK81099A3 (no)
TR (1) TR199901423T2 (no)
TW (1) TW434221B (no)
WO (1) WO1998028310A1 (no)
ZA (1) ZA9711431B (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001235466B2 (en) 2000-02-16 2004-04-22 Glaxo Group Limited Pyrimidine-4-one derivatives as LDL-PLA2 inhibitors
JP2003525303A (ja) * 2000-02-29 2003-08-26 メディキュア インターナショナル インコーポレイテッド 心臓保護ホスホン酸塩およびマロン酸塩
EP1531157B1 (en) * 2000-02-29 2008-03-19 Medicure International Inc. Cardioprotective phosphonates
US20030114421A1 (en) * 2000-09-27 2003-06-19 Phan Hieu Trung Alpha-substituted beta-aminoethyl phosphonate derivatives
CN1489596A (zh) * 2000-09-27 2004-04-14 �Ʒ� α-取代的β-氨基乙基膦酸酯类化合物
GB0024808D0 (en) 2000-10-10 2000-11-22 Smithkline Beecham Plc Novel compounds
GB0025849D0 (en) * 2000-10-23 2000-12-06 Smithkline Beecham Plc Novel compounds
MXPA04007797A (es) * 2002-02-11 2005-09-08 Ilex Products Inc Derivados de fosfonato heteroarilalquilo a-sustituidos.
EP1482897A2 (en) * 2002-02-19 2004-12-08 Ilex Products, Inc. Aminodiphosphonate apolipoprotein e modulators
JP4824968B2 (ja) * 2005-08-18 2011-11-30 株式会社クレハ ホスホン酸誘導体及びその酸付加塩、並びにそれを用いた農園芸用病害防除剤
EP2649053B1 (en) 2010-12-06 2015-11-04 Glaxo Group Limited Pyrimidinone compounds for use in the treatment of diseases or conditions mediated by lp-pla2
EP2739627A4 (en) 2011-07-27 2015-01-21 Glaxo Group Ltd 2,3-DIHYDROIMIDAZO [1,2-C] PYRIMIDIN-5 (1H) -ONE COMPOUNDS AND USE AS INHIBITORS OF LP-PLA2
US9273054B2 (en) 2011-07-27 2016-03-01 Glaxo Group Limited Substituted pyrimido[1,6-a]pyrimidines as Lp-PLA2 inhibitors
MY172885A (en) 2011-09-01 2019-12-13 Glaxo Group Ltd Novel crystal form
RU2015135806A (ru) 2013-01-25 2017-03-03 Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед Соединения
KR20150108896A (ko) 2013-01-25 2015-09-30 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 Lp-pla2의 억제제로서의 비시클릭 피리미돈 화합물
UY35276A (es) 2013-01-25 2014-08-29 Glaxosmithkline Ip Dev Ltd Nuevos compuestos que inhiben la actividad de Lp-PLA2
WO2016012916A1 (en) 2014-07-22 2016-01-28 Glaxosmithkline Intellectual Property Development Limited 1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidine derivatives useful in the treatment of diseases and disorders mediated by lp-pla2
WO2016012917A1 (en) 2014-07-22 2016-01-28 Glaxosmithkline Intellectual Property Development Limited 1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidine derivatives useful in the treatment of diseases and disorders mediated by lp-pla2
PE20230092A1 (es) 2019-11-09 2023-01-16 Shanghai Simr Biotechnology Co Ltd Derivado triciclico de dihidroimidazopirimidona, metodo de preparacion del mismo, composicion farmaceuticas y uso del mismo
CN115304620A (zh) 2021-05-07 2022-11-08 上海赛默罗生物科技有限公司 嘧啶酮衍生物、其制备方法、药物组合物和用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH683996A5 (fr) * 1992-03-05 1994-06-30 Symphar Sa Dérivés aminophosphonates substitués, leur procédé de préparation et compositions pharmaceutiques les contenant.
DE4433244A1 (de) * 1994-09-19 1996-03-28 Hoechst Ag Aminomethylphosphon- und Aminomethylphosphinsäure-Derivate und deren Verwendung zur Behandlung von degenerativen Gelenkserkrankungen
CH690264A5 (fr) 1995-06-30 2000-06-30 Symphar Sa Dérivés aminophosphonates substitués, leur procédé de préparation et leur utilisation pour la préparation de compositions pharmaceutiques.
GB9626536D0 (en) 1996-12-20 1997-02-05 Symphar Sa Novel compounds

Also Published As

Publication number Publication date
OA11068A (en) 2003-03-10
US6303784B1 (en) 2001-10-16
CO4930276A1 (es) 2000-06-27
GB9626615D0 (en) 1997-02-05
NO993001D0 (no) 1999-06-18
ATE255117T1 (de) 2003-12-15
ID22053A (id) 1999-08-26
AR008541A1 (es) 2000-01-19
NZ335884A (en) 2000-11-24
AU5858898A (en) 1998-07-17
NO993001L (no) 1999-06-18
US20020082423A1 (en) 2002-06-27
DZ2377A1 (fr) 2002-12-28
TR199901423T2 (xx) 1999-10-21
EA199900580A1 (ru) 1999-12-29
HUP0002171A3 (en) 2002-12-28
ZA9711431B (en) 1999-06-21
BG103574A (bg) 2000-11-30
CA2275696A1 (en) 1998-07-02
WO1998028310A1 (en) 1998-07-02
PL334189A1 (en) 2000-02-14
TW434221B (en) 2001-05-16
PE46799A1 (es) 1999-06-24
KR20000069609A (ko) 2000-11-25
DE69726449T2 (de) 2004-08-26
HUP0002171A2 (hu) 2001-05-28
EP0946572B1 (en) 2003-11-26
CN1240451A (zh) 2000-01-05
AP9901546A0 (en) 1999-06-30
BR9714650A (pt) 2000-10-03
MA24427A1 (fr) 1998-07-01
CN1105117C (zh) 2003-04-09
DE69726449D1 (en) 2004-01-08
SK81099A3 (en) 1999-11-08
EP0946572A1 (en) 1999-10-06
JP2001506667A (ja) 2001-05-22

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