US5741908A
(en)
|
1996-06-21 |
1998-04-21 |
Minnesota Mining And Manufacturing Company |
Process for reparing imidazoquinolinamines
|
HUP9904665A3
(en)
*
|
1996-10-25 |
2000-11-28 |
Minnesota Mining And Mfg Co Sa |
Immune response modifier compounds for treatment of th2 mediated and related diseases
|
US20060002959A1
(en)
*
|
1996-11-14 |
2006-01-05 |
Government Of The United States |
Skin-sctive adjuvants for transcutaneous immuization
|
US5980898A
(en)
*
|
1996-11-14 |
1999-11-09 |
The United States Of America As Represented By The U.S. Army Medical Research & Material Command |
Adjuvant for transcutaneous immunization
|
US6797276B1
(en)
*
|
1996-11-14 |
2004-09-28 |
The United States Of America As Represented By The Secretary Of The Army |
Use of penetration enhancers and barrier disruption agents to enhance the transcutaneous immune response
|
US20060002949A1
(en)
*
|
1996-11-14 |
2006-01-05 |
Army Govt. Of The Usa, As Rep. By Secretary Of The Office Of The Command Judge Advocate, Hq Usamrmc. |
Transcutaneous immunization without heterologous adjuvant
|
US20040258703A1
(en)
*
|
1997-11-14 |
2004-12-23 |
The Government Of The Us, As Represented By The Secretary Of The Army |
Skin-active adjuvants for transcutaneous immunization
|
WO1999028321A1
(fr)
|
1997-11-28 |
1999-06-10 |
Sumitomo Pharmaceuticals Company, Limited |
Nouveaux composes heterocycliques
|
UA67760C2
(uk)
*
|
1997-12-11 |
2004-07-15 |
Міннесота Майнінг Енд Мануфакчурінг Компані |
Імідазонафтиридин та тетрагідроімідазонафтиридин, фармацевтична композиція, спосіб індукування біосинтезу цитокінів та спосіб лікування вірусної інфекції, проміжні сполуки
|
US6518280B2
(en)
|
1998-12-11 |
2003-02-11 |
3M Innovative Properties Company |
Imidazonaphthyridines
|
US6558951B1
(en)
*
|
1999-02-11 |
2003-05-06 |
3M Innovative Properties Company |
Maturation of dendritic cells with immune response modifying compounds
|
EP1165132B1
(de)
*
|
1999-04-08 |
2011-10-19 |
Intercell USA, Inc. |
Trockenformulierung für transkutane immunisierung
|
US6331539B1
(en)
*
|
1999-06-10 |
2001-12-18 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
US6756382B2
(en)
|
1999-06-10 |
2004-06-29 |
3M Innovative Properties Company |
Amide substituted imidazoquinolines
|
US6573273B1
(en)
|
1999-06-10 |
2003-06-03 |
3M Innovative Properties Company |
Urea substituted imidazoquinolines
|
US6541485B1
(en)
|
1999-06-10 |
2003-04-01 |
3M Innovative Properties Company |
Urea substituted imidazoquinolines
|
US6916925B1
(en)
|
1999-11-05 |
2005-07-12 |
3M Innovative Properties Co. |
Dye labeled imidazoquinoline compounds
|
US6376669B1
(en)
|
1999-11-05 |
2002-04-23 |
3M Innovative Properties Company |
Dye labeled imidazoquinoline compounds
|
JP3436512B2
(ja)
*
|
1999-12-28 |
2003-08-11 |
株式会社デンソー |
アクセル装置
|
US6894060B2
(en)
*
|
2000-03-30 |
2005-05-17 |
3M Innovative Properties Company |
Method for the treatment of dermal lesions caused by envenomation
|
JP2002145777A
(ja)
*
|
2000-11-06 |
2002-05-22 |
Sumitomo Pharmaceut Co Ltd |
アラキドン酸誘発皮膚疾患治療剤
|
US6677348B2
(en)
|
2000-12-08 |
2004-01-13 |
3M Innovative Properties Company |
Aryl ether substituted imidazoquinolines
|
UA74852C2
(en)
*
|
2000-12-08 |
2006-02-15 |
3M Innovative Properties Co |
Urea-substituted imidazoquinoline ethers
|
CA2598144A1
(en)
*
|
2000-12-08 |
2006-08-31 |
3M Innovative Properties Company |
Compositions and methods for targeted delivery of immune response modifiers
|
US6660735B2
(en)
|
2000-12-08 |
2003-12-09 |
3M Innovative Properties Company |
Urea substituted imidazoquinoline ethers
|
US6664260B2
(en)
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Heterocyclic ether substituted imidazoquinolines
|
US6664265B2
(en)
*
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Amido ether substituted imidazoquinolines
|
US6545016B1
(en)
*
|
2000-12-08 |
2003-04-08 |
3M Innovative Properties Company |
Amide substituted imidazopyridines
|
US6667312B2
(en)
*
|
2000-12-08 |
2003-12-23 |
3M Innovative Properties Company |
Thioether substituted imidazoquinolines
|
US6677347B2
(en)
*
|
2000-12-08 |
2004-01-13 |
3M Innovative Properties Company |
Sulfonamido ether substituted imidazoquinolines
|
US6525064B1
(en)
|
2000-12-08 |
2003-02-25 |
3M Innovative Properties Company |
Sulfonamido substituted imidazopyridines
|
AU2002232498B2
(en)
*
|
2000-12-08 |
2006-05-04 |
3M Innovative Properties Company |
Screening method for identifying compounds that selectively induce interferon alpha
|
US20020107262A1
(en)
*
|
2000-12-08 |
2002-08-08 |
3M Innovative Properties Company |
Substituted imidazopyridines
|
US6660747B2
(en)
|
2000-12-08 |
2003-12-09 |
3M Innovative Properties Company |
Amido ether substituted imidazoquinolines
|
US6545017B1
(en)
|
2000-12-08 |
2003-04-08 |
3M Innovative Properties Company |
Urea substituted imidazopyridines
|
US6664264B2
(en)
*
|
2000-12-08 |
2003-12-16 |
3M Innovative Properties Company |
Thioether substituted imidazoquinolines
|
CA2437899C
(en)
*
|
2001-02-13 |
2012-05-15 |
Gregory M. Glenn |
Vaccine for transcutaneous immunization against etec-caused traveler's diarrhea
|
US7226928B2
(en)
*
|
2001-06-15 |
2007-06-05 |
3M Innovative Properties Company |
Methods for the treatment of periodontal disease
|
JP2005501550A
(ja)
*
|
2001-08-30 |
2005-01-20 |
スリーエム イノベイティブ プロパティズ カンパニー |
免疫反応調整剤分子を用いた形質細胞様樹状細胞を成熟させる方法
|
WO2003094836A2
(en)
*
|
2001-10-12 |
2003-11-20 |
University Of Iowa Research Foundation |
Methods and products for enhancing immune responses using imidazoquinoline compounds
|
EP1455700A4
(de)
*
|
2001-11-16 |
2007-02-14 |
3M Innovative Properties Co |
Verfahren und zusammensetzungen im zusammenhang mit irm-verbindungen und toll-rezeptor-pfaden
|
US7321033B2
(en)
|
2001-11-27 |
2008-01-22 |
Anadys Pharmaceuticals, Inc. |
3-B-D-ribofuranosylthiazolo [4,5-d] pyrimidine nucleosides and uses thereof
|
NZ532769A
(en)
*
|
2001-11-29 |
2005-12-23 |
3M Innovative Properties Co |
Pharmaceutical formulations comprising an immune response modifier
|
CA2365732A1
(en)
*
|
2001-12-20 |
2003-06-20 |
Ibm Canada Limited-Ibm Canada Limitee |
Testing measurements
|
US6677349B1
(en)
*
|
2001-12-21 |
2004-01-13 |
3M Innovative Properties Company |
Sulfonamide and sulfamide substituted imidazoquinolines
|
WO2003072026A2
(en)
*
|
2002-02-22 |
2003-09-04 |
3M Innovative Properties Company |
Method of reducing and treating uvb-induced immunosuppression
|
EP2368431A1
(de)
|
2002-04-04 |
2011-09-28 |
Coley Pharmaceutical GmbH |
Immunstimulierende G,U-haltige Oligoribonucleotide
|
EP1513524A4
(de)
*
|
2002-06-07 |
2008-09-03 |
3M Innovative Properties Co |
Mit äther substituierte imidazopyridine
|
DK1545597T3
(da)
|
2002-08-15 |
2011-01-31 |
3M Innovative Properties Co |
Immunstimulerende sammensætninger og fremgangsmåde til stimulering af en immunrespons
|
JP2006503068A
(ja)
*
|
2002-09-26 |
2006-01-26 |
スリーエム イノベイティブ プロパティズ カンパニー |
1h−イミダゾダイマー
|
WO2004053057A2
(en)
*
|
2002-12-11 |
2004-06-24 |
3M Innovative Properties Company |
Gene expression systems and recombinant cell lines
|
AU2003287316A1
(en)
*
|
2002-12-11 |
2004-06-30 |
3M Innovative Properties Company |
Assays relating to toll-like receptor activity
|
AU2003301052A1
(en)
|
2002-12-20 |
2004-07-22 |
3M Innovative Properties Company |
Aryl / hetaryl substituted imidazoquinolines
|
AU2003300184B8
(en)
|
2002-12-30 |
2009-12-03 |
3M Innovative Properties Company |
Immunostimulatory combinations
|
US20050267144A1
(en)
*
|
2003-01-06 |
2005-12-01 |
Eugene Mandrea |
Methods of stimulating immune response in virally infected individuals
|
US7893083B2
(en)
*
|
2003-01-06 |
2011-02-22 |
Eugene Mandrea |
Method of treating genital herpes
|
US20060183767A1
(en)
*
|
2003-01-06 |
2006-08-17 |
Eugene Mandrea |
Methods of stimulating immune response in certain individuals
|
WO2004071459A2
(en)
*
|
2003-02-13 |
2004-08-26 |
3M Innovative Properties Company |
Methods and compositions related to irm compounds and toll-like receptor 8
|
JP2006519020A
(ja)
*
|
2003-02-27 |
2006-08-24 |
スリーエム イノベイティブ プロパティズ カンパニー |
Tlr介在生物活性の選択的調節
|
US8110582B2
(en)
|
2003-03-04 |
2012-02-07 |
3M Innovative Properties Company |
Prophylactic treatment of UV-induced epidermal neoplasia
|
KR20050107497A
(ko)
*
|
2003-03-07 |
2005-11-11 |
쓰리엠 이노베이티브 프로퍼티즈 컴파니 |
1-아미노 1h-이미다조퀴놀린
|
US7163947B2
(en)
*
|
2003-03-07 |
2007-01-16 |
3M Innovative Properties Company |
1-Amino 1H-imidazoquinolines
|
KR20050109562A
(ko)
*
|
2003-03-13 |
2005-11-21 |
쓰리엠 이노베이티브 프로퍼티즈 컴파니 |
피부의 질을 개선시키는 방법
|
WO2004080293A2
(en)
*
|
2003-03-13 |
2004-09-23 |
3M Innovative Properties Company |
Methods for diagnosing skin lesions
|
EP1603476A4
(de)
|
2003-03-13 |
2010-01-13 |
3M Innovative Properties Co |
Verfahren zur entfernung von tätowierungen
|
US20040192585A1
(en)
|
2003-03-25 |
2004-09-30 |
3M Innovative Properties Company |
Treatment for basal cell carcinoma
|
US7923560B2
(en)
*
|
2003-04-10 |
2011-04-12 |
3M Innovative Properties Company |
Delivery of immune response modifier compounds
|
US20040265351A1
(en)
*
|
2003-04-10 |
2004-12-30 |
Miller Richard L. |
Methods and compositions for enhancing immune response
|
US20040214851A1
(en)
*
|
2003-04-28 |
2004-10-28 |
3M Innovative Properties Company |
Compositions and methods for induction of opioid receptors
|
US20040242620A1
(en)
*
|
2003-05-20 |
2004-12-02 |
3M Innovative Properties Company |
Immune response modifier compounds for treatment of TH2 mediated and related diseases
|
US20050032829A1
(en)
*
|
2003-06-06 |
2005-02-10 |
3M Innovative Properties Company |
Process for imidazo[4,5-c]pyridin-4-amines
|
US6943255B2
(en)
*
|
2003-06-06 |
2005-09-13 |
3M Innovative Properties Company |
Process for imidazo[4,5-c]pyridin-4-amines
|
MXPA06001004A
(es)
*
|
2003-07-31 |
2006-04-27 |
3M Innovative Properties Co |
Composiciones para encapsulacion y liberacion controlada.
|
WO2005016275A2
(en)
*
|
2003-08-05 |
2005-02-24 |
3M Innovative Properties Company |
Formulations containing an immune response modifier
|
US8211906B1
(en)
|
2003-08-05 |
2012-07-03 |
Scherrer Lawrence C |
Method of inhibiting growth of neoplastic cells and inhibiting infection by administering an immune enhancer drug
|
MXPA06001674A
(es)
*
|
2003-08-12 |
2006-05-12 |
3M Innovative Properties Co |
Compuestos que contienen imidazo hidroxilamina-sustituidos.
|
AU2004266657B2
(en)
*
|
2003-08-14 |
2009-07-02 |
3M Innovative Properties Company |
Lipid-modified immune response modifiers
|
JP2007503268A
(ja)
*
|
2003-08-25 |
2007-02-22 |
スリーエム イノベイティブ プロパティズ カンパニー |
免疫応答修飾化合物の送達
|
EP1660122A4
(de)
*
|
2003-08-25 |
2007-10-24 |
3M Innovative Properties Co |
Immunstimulatorische kombinationen und behandlungen
|
EP1658076B1
(de)
*
|
2003-08-27 |
2013-03-06 |
3M Innovative Properties Company |
Aryloxy- und arylalkylenoxy-substituierte imidazochinoline
|
JP2007504172A
(ja)
*
|
2003-09-02 |
2007-03-01 |
スリーエム イノベイティブ プロパティズ カンパニー |
粘膜に関連した症状の処置に関する方法
|
ATE465742T1
(de)
|
2003-09-05 |
2010-05-15 |
Anadys Pharmaceuticals Inc |
Tlr7-liganden zur behandlung von hepatitis c
|
EP1660026A4
(de)
*
|
2003-09-05 |
2008-07-16 |
3M Innovative Properties Co |
Behandlung von cd5+ b-zell-lyphom
|
JP2007505629A
(ja)
*
|
2003-09-17 |
2007-03-15 |
スリーエム イノベイティブ プロパティズ カンパニー |
Tlr遺伝子発現の選択的調節
|
US7544697B2
(en)
*
|
2003-10-03 |
2009-06-09 |
Coley Pharmaceutical Group, Inc. |
Pyrazolopyridines and analogs thereof
|
AU2004278014B2
(en)
|
2003-10-03 |
2011-04-28 |
3M Innovative Properties Company |
Alkoxy substituted imidazoquinolines
|
CA2540598C
(en)
|
2003-10-03 |
2013-09-24 |
3M Innovative Properties Company |
Pyrazolopyridines and analogs thereof
|
US20090075980A1
(en)
*
|
2003-10-03 |
2009-03-19 |
Coley Pharmaceutical Group, Inc. |
Pyrazolopyridines and Analogs Thereof
|
AU2004285575A1
(en)
*
|
2003-10-31 |
2005-05-12 |
3M Innovative Properties Company |
Neutrophil activation by immune response modifier compounds
|
CN1906192A
(zh)
|
2003-11-14 |
2007-01-31 |
3M创新有限公司 |
羟胺取代的咪唑环化合物
|
EP1685129A4
(de)
*
|
2003-11-14 |
2008-10-22 |
3M Innovative Properties Co |
Oximsubstituierte imidazoringverbindungen
|
CA2547085A1
(en)
*
|
2003-11-25 |
2005-06-09 |
3M Innovative Properties Company |
Hydroxylamine and oxime substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
AR046781A1
(es)
|
2003-11-25 |
2005-12-21 |
3M Innovative Properties Co |
Derivados de imidazoquinolinas. composiciones farmaceuticas.
|
WO2005055932A2
(en)
*
|
2003-12-02 |
2005-06-23 |
3M Innovative Properties Company |
Therapeutic combinations and methods including irm compounds
|
US20050226878A1
(en)
*
|
2003-12-02 |
2005-10-13 |
3M Innovative Properties Company |
Therapeutic combinations and methods including IRM compounds
|
CN1914203A
(zh)
*
|
2003-12-04 |
2007-02-14 |
3M创新有限公司 |
砜取代的咪唑环醚
|
WO2005066170A1
(en)
*
|
2003-12-29 |
2005-07-21 |
3M Innovative Properties Company |
Arylalkenyl and arylalkynyl substituted imidazoquinolines
|
WO2005066172A1
(en)
*
|
2003-12-29 |
2005-07-21 |
3M Innovative Properties Company |
Piperazine, [1,4]diazepane, [1,4]diazocane, and [1,5]diazocane fused imidazo ring compounds
|
CA2551399A1
(en)
*
|
2003-12-30 |
2005-07-21 |
3M Innovative Properties Company |
Imidazoquinolinyl, imidazopyridinyl, and imidazonaphthyridinyl sulfonamides
|
US20050239735A1
(en)
*
|
2003-12-30 |
2005-10-27 |
3M Innovative Properties Company |
Enhancement of immune responses
|
AU2005230938A1
(en)
*
|
2004-02-19 |
2005-10-20 |
Coley Pharmaceutical Gmbh |
Immunostimulatory viral RNA oligonucleotides
|
US20050201959A1
(en)
*
|
2004-03-11 |
2005-09-15 |
Vvii Newco 2003, Inc. |
Methods and compositions for altering skin coloration
|
CA2559607C
(en)
*
|
2004-03-15 |
2013-02-19 |
3M Innovative Properties Company |
Immune response modifier formulations and methods
|
WO2005094531A2
(en)
*
|
2004-03-24 |
2005-10-13 |
3M Innovative Properties Company |
Amide substituted imidazopyridines, imidazoquinolines, and imidazonaphthyridines
|
US20070166384A1
(en)
*
|
2004-04-09 |
2007-07-19 |
Zarraga Isidro Angelo E |
Methods , composition and preparations for delivery of immune response modifiers
|
CA2564855A1
(en)
*
|
2004-04-28 |
2005-10-28 |
3M Innovative Properties Company |
Compositions and methods for mucosal vaccination
|
US20050267145A1
(en)
*
|
2004-05-28 |
2005-12-01 |
Merrill Bryon A |
Treatment for lung cancer
|
US20080015184A1
(en)
*
|
2004-06-14 |
2008-01-17 |
3M Innovative Properties Company |
Urea Substituted Imidazopyridines, Imidazoquinolines, and Imidazonaphthyridines
|
WO2005123080A2
(en)
*
|
2004-06-15 |
2005-12-29 |
3M Innovative Properties Company |
Nitrogen-containing heterocyclyl substituted imidazoquinolines and imidazonaphthyridines
|
WO2006009826A1
(en)
*
|
2004-06-18 |
2006-01-26 |
3M Innovative Properties Company |
Aryloxy and arylalkyleneoxy substituted thiazoloquinolines and thiazolonaphthyridines
|
US8541438B2
(en)
|
2004-06-18 |
2013-09-24 |
3M Innovative Properties Company |
Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
WO2006065280A2
(en)
*
|
2004-06-18 |
2006-06-22 |
3M Innovative Properties Company |
Isoxazole, dihydroisoxazole, and oxadiazole substituted imidazo ring compounds and methods
|
US20070259881A1
(en)
*
|
2004-06-18 |
2007-11-08 |
Dellaria Joseph F Jr |
Substituted Imidazo Ring Systems and Methods
|
WO2006038923A2
(en)
*
|
2004-06-18 |
2006-04-13 |
3M Innovative Properties Company |
Aryl substituted imidazonaphthyridines
|
US7884207B2
(en)
*
|
2004-06-18 |
2011-02-08 |
3M Innovative Properties Company |
Substituted imidazoquinolines, imidazopyridines, and imidazonaphthyridines
|
US20060045886A1
(en)
*
|
2004-08-27 |
2006-03-02 |
Kedl Ross M |
HIV immunostimulatory compositions
|
WO2006029115A2
(en)
|
2004-09-02 |
2006-03-16 |
3M Innovative Properties Company |
2-amino 1h imidazo ring systems and methods
|
US20090270443A1
(en)
*
|
2004-09-02 |
2009-10-29 |
Doris Stoermer |
1-amino imidazo-containing compounds and methods
|
PL1789042T3
(pl)
*
|
2004-09-02 |
2012-09-28 |
3M Innovative Properties Co |
Układy pierścieni 1-alkoksy 1H-imidazo i sposoby
|
WO2006029223A2
(en)
*
|
2004-09-08 |
2006-03-16 |
Children's Medical Center Corporation |
Method for stimulating the immune response of newborns
|
WO2006042254A2
(en)
*
|
2004-10-08 |
2006-04-20 |
3M Innovative Properties Company |
Adjuvant for dna vaccines
|
US9492400B2
(en)
*
|
2004-11-04 |
2016-11-15 |
Massachusetts Institute Of Technology |
Coated controlled release polymer particles as efficient oral delivery vehicles for biopharmaceuticals
|
WO2006063072A2
(en)
*
|
2004-12-08 |
2006-06-15 |
3M Innovative Properties Company |
Immunomodulatory compositions, combinations and methods
|
ES2525567T3
(es)
|
2004-12-17 |
2014-12-26 |
Anadys Pharmaceuticals, Inc. |
Compuestos de 3H-oxazolo y 3H-tiazolo[4,5-d]pirimidin-2-ona 3,5-disustituidos y 3,5,7-trisustituidos y profármacos de los mismos
|
US8080560B2
(en)
*
|
2004-12-17 |
2011-12-20 |
3M Innovative Properties Company |
Immune response modifier formulations containing oleic acid and methods
|
JP2008526751A
(ja)
*
|
2004-12-30 |
2008-07-24 |
武田薬品工業株式会社 |
1−(2−メチルプロピル)−1h−イミダゾ[4,5−c][1,5]ナフチリジン−4−アミンエタンスルホナート及び1−(2−メチルプロピル)−1h−イミダゾ[4,5−c][1,5]ナフチリジン−4−アミンメタンスルホナート
|
EP1831221B1
(de)
|
2004-12-30 |
2012-08-08 |
3M Innovative Properties Company |
Substituierte, chirale, fusionierte 1,2 imidazo-4,5-c-ringverbindungen
|
AU2005322898B2
(en)
|
2004-12-30 |
2011-11-24 |
3M Innovative Properties Company |
Chiral fused (1,2)imidazo(4,5-c) ring compounds
|
US8436176B2
(en)
*
|
2004-12-30 |
2013-05-07 |
Medicis Pharmaceutical Corporation |
Process for preparing 2-methyl-1-(2-methylpropyl)-1H-imidazo[4,5-c][1,5]naphthyridin-4-amine
|
JP2008526765A
(ja)
*
|
2004-12-30 |
2008-07-24 |
スリーエム イノベイティブ プロパティズ カンパニー |
皮膚転移の処置
|
JP2008530022A
(ja)
*
|
2005-02-04 |
2008-08-07 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
免疫反応調節物質を含む水性ゲル処方物
|
EP1877056A2
(de)
|
2005-02-09 |
2008-01-16 |
Coley Pharmaceutical Group, Inc. |
Oxim- und hydroxylaminsubstituierte thiazol-4,5-c-ringverbindungen und verfahren dafür
|
CA2597324C
(en)
|
2005-02-09 |
2015-06-30 |
Coley Pharmaceutical Group, Inc. |
Alkyloxy substituted thiazoloquinolines and thiazolonaphthyridines
|
AU2006213746A1
(en)
|
2005-02-11 |
2006-08-17 |
Coley Pharmaceutical Group, Inc. |
Oxime and hydroxylamine substituted imidazo(4,5-c) ring compounds and methods
|
CA2597446A1
(en)
*
|
2005-02-11 |
2006-08-31 |
Coley Pharmaceutical Group, Inc. |
Substituted imidazoquinolines and imidazonaphthyridines
|
EP1851220A2
(de)
|
2005-02-23 |
2007-11-07 |
3M Innovative Properties Company |
Hydroxyalkylsubstituierte imidazonaphthyridine
|
WO2006091647A2
(en)
*
|
2005-02-23 |
2006-08-31 |
Coley Pharmaceutical Group, Inc. |
Method of preferentially inducing the biosynthesis of interferon
|
US8178677B2
(en)
*
|
2005-02-23 |
2012-05-15 |
3M Innovative Properties Company |
Hydroxyalkyl substituted imidazoquinolines
|
WO2006091567A2
(en)
*
|
2005-02-23 |
2006-08-31 |
Coley Pharmaceutical Group, Inc. |
Hydroxyalkyl substituted imidazoquinoline compounds and methods
|
JP2008533148A
(ja)
|
2005-03-14 |
2008-08-21 |
スリーエム イノベイティブ プロパティズ カンパニー |
光線性角化症の治療方法
|
JP2008535832A
(ja)
|
2005-04-01 |
2008-09-04 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
ピラゾロピリジン−1,4−ジアミン、およびそのアナログ
|
US7943636B2
(en)
|
2005-04-01 |
2011-05-17 |
3M Innovative Properties Company |
1-substituted pyrazolo (3,4-C) ring compounds as modulators of cytokine biosynthesis for the treatment of viral infections and neoplastic diseases
|
AU2006241166A1
(en)
*
|
2005-04-25 |
2006-11-02 |
3M Innovative Properties Company |
Immunostimulatory compositions
|
JP2009504803A
(ja)
|
2005-08-22 |
2009-02-05 |
ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア |
Tlrアゴニスト
|
JP2009507856A
(ja)
*
|
2005-09-09 |
2009-02-26 |
コーリー ファーマシューティカル グループ,インコーポレイテッド |
N−{2−[4−アミノ−2−(エトキシメチル)−1H−イミダゾ[4,5−c]キノリン−1−イル]−1,1−ジメチルエチル}メタンスルホンアミドのアミドおよびカルバマート誘導体ならびに方法
|
ZA200803029B
(en)
*
|
2005-09-09 |
2009-02-25 |
Coley Pharm Group Inc |
Amide and carbamate derivatives of alkyl substituted /V-[4-(4-amino-1H-imidazo[4,5-c] quinolin-1-yl)butyl] methane-sulfonamides and methods
|
US20070081962A1
(en)
*
|
2005-10-06 |
2007-04-12 |
Amit Munshi |
Novel delivery of immune response modifiers for removal of chronic tattoos
|
AU2006311871B2
(en)
|
2005-11-04 |
2011-03-03 |
3M Innovative Properties Company |
Hydroxy and alkoxy substituted 1H-imidazoquinolines and methods
|
BRPI0618789A2
(pt)
|
2005-11-21 |
2016-08-30 |
Anadys Pharmaceuticals Inc |
processos de preparação de 5-amino-3h-tiazol [4,5-d] pirimidin-2-ona, de ciclocondensação de 2,4-diamino-5-halo-pirimidina e de oxidação de 5-amino-3h-tiazol [4,5-d] pirimidin-2-tiona
|
US9267937B2
(en)
|
2005-12-15 |
2016-02-23 |
Massachusetts Institute Of Technology |
System for screening particles
|
WO2007079203A2
(en)
*
|
2005-12-28 |
2007-07-12 |
3M Innovative Properties Company |
Treatment for cutaneous t cell lymphoma
|
US8951528B2
(en)
|
2006-02-22 |
2015-02-10 |
3M Innovative Properties Company |
Immune response modifier conjugates
|
WO2007106854A2
(en)
*
|
2006-03-15 |
2007-09-20 |
Coley Pharmaceutical Group, Inc. |
Hydroxy and alkoxy substituted 1h-imidazonaphthyridines and methods
|
EP2007435B1
(de)
|
2006-03-31 |
2019-12-18 |
Massachusetts Institute Of Technology |
System zur gezielten verabreichung von heilmitteln
|
CA2652280C
(en)
|
2006-05-15 |
2014-01-28 |
Massachusetts Institute Of Technology |
Polymers for functional particles
|
WO2007137117A2
(en)
*
|
2006-05-17 |
2007-11-29 |
Massachusetts Institute Of Technology |
Aptamer-directed drug delivery
|
WO2007142755A2
(en)
|
2006-05-31 |
2007-12-13 |
The Regents Of The University Of California |
Purine analogs
|
DE602007012247D1
(de)
|
2006-06-22 |
2011-03-10 |
Anadys Pharmaceuticals Inc |
Prodrugs von 5-amino-3-(3'-deoxy-beta-d-ribofuranosyl)-thiazolä4,5-düpyrimidin-2,7-dion
|
WO2007150030A2
(en)
*
|
2006-06-23 |
2007-12-27 |
Massachusetts Institute Of Technology |
Microfluidic synthesis of organic nanoparticles
|
WO2008008432A2
(en)
*
|
2006-07-12 |
2008-01-17 |
Coley Pharmaceutical Group, Inc. |
Substituted chiral fused( 1,2) imidazo (4,5-c) ring compounds and methods
|
BRPI0714831A2
(pt)
|
2006-07-18 |
2013-04-02 |
Anadys Pharmaceuticals Inc |
composto, composiÇço farmacÊutica e mÉtodos de modulaÇço de atividades imuno da citoquina em paciente, de tratamento de infecÇço de vÍrus c da hepatite em paciente e de desordem relacionada com proliferaÇço em mamÍfero necessitado do mesmo
|
US20100092401A1
(en)
*
|
2006-07-18 |
2010-04-15 |
Graceway Pharmaceuticals, Llc |
Immune response modifier formulations
|
WO2008016475A2
(en)
|
2006-07-31 |
2008-02-07 |
3M Innovative Properties Company |
Immune response modifier compositions and methods
|
US20100144845A1
(en)
*
|
2006-08-04 |
2010-06-10 |
Massachusetts Institute Of Technology |
Oligonucleotide systems for targeted intracellular delivery
|
WO2008030511A2
(en)
*
|
2006-09-06 |
2008-03-13 |
Coley Pharmaceuticial Group, Inc. |
Substituted 3,4,6,7-tetrahydro-5h, 1,2a,4a,8-tetraazacyclopenta[cd]phenalenes
|
US20100303723A1
(en)
*
|
2006-11-20 |
2010-12-02 |
Massachusetts Institute Of Technology |
Drug delivery systems using fc fragments
|
US20080149123A1
(en)
|
2006-12-22 |
2008-06-26 |
Mckay William D |
Particulate material dispensing hairbrush with combination bristles
|
CN101790380B
(zh)
|
2007-02-07 |
2013-07-10 |
加利福尼亚大学董事会 |
合成tlr激动剂的缀合物及其应用
|
US9217129B2
(en)
|
2007-02-09 |
2015-12-22 |
Massachusetts Institute Of Technology |
Oscillating cell culture bioreactor
|
US20090074828A1
(en)
*
|
2007-04-04 |
2009-03-19 |
Massachusetts Institute Of Technology |
Poly(amino acid) targeting moieties
|
WO2009026292A1
(en)
|
2007-08-20 |
2009-02-26 |
Anadys Pharmaceuticals, Inc. |
Dosing methods for treating disease
|
CN105770878A
(zh)
|
2007-10-12 |
2016-07-20 |
麻省理工学院 |
疫苗纳米技术
|
WO2009099650A2
(en)
*
|
2008-02-07 |
2009-08-13 |
Carson Dennis A |
Treatment of bladder diseases with a tlr7 activator
|
US8591905B2
(en)
|
2008-10-12 |
2013-11-26 |
The Brigham And Women's Hospital, Inc. |
Nicotine immunonanotherapeutics
|
US8343497B2
(en)
*
|
2008-10-12 |
2013-01-01 |
The Brigham And Women's Hospital, Inc. |
Targeting of antigen presenting cells with immunonanotherapeutics
|
US8277812B2
(en)
|
2008-10-12 |
2012-10-02 |
Massachusetts Institute Of Technology |
Immunonanotherapeutics that provide IgG humoral response without T-cell antigen
|
US8343498B2
(en)
|
2008-10-12 |
2013-01-01 |
Massachusetts Institute Of Technology |
Adjuvant incorporation in immunonanotherapeutics
|
WO2010088924A1
(en)
|
2009-02-06 |
2010-08-12 |
Telormedix Sa |
Pharmaceutical compositions comprising imidazoquinolin(amines) and derivatives thereof suitable for local administration
|
BRPI1008383A2
(pt)
*
|
2009-02-11 |
2016-02-23 |
Univ California |
composto, composição farmacêutica, método para prevenir, inibir ou tratar uma condição, e, uso de um composto
|
MX2011010050A
(es)
|
2009-03-25 |
2011-12-14 |
Univ Texas |
Composiciones para estimulación de resistencia inmune innata de mamiferos a patógenos.
|
EA201101530A1
(ru)
*
|
2009-04-21 |
2012-03-30 |
Селекта Байосайенсиз, Инк. |
ИММУНОНАНОТЕРАПИЯ, ОБЕСПЕЧИВАЮЩАЯ Th1-СМЕЩЕННЫЙ ОТВЕТ
|
EP2435092A2
(de)
|
2009-05-27 |
2012-04-04 |
Selecta Biosciences, Inc. |
Nanoträger mit komponenten mit verschiedenen freisetzungsraten
|
US20110033515A1
(en)
*
|
2009-08-04 |
2011-02-10 |
Rst Implanted Cell Technology |
Tissue contacting material
|
EA201592264A1
(ru)
|
2009-08-26 |
2016-08-31 |
Селекта Байосайенсиз, Инк. |
Композиции, которые индуцируют хелперное действие т-клеток
|
ES2661978T3
(es)
|
2010-05-26 |
2018-04-04 |
Selecta Biosciences, Inc. |
Vacunas multivalentes de nanovehículos sintéticos
|
CN105294684B
(zh)
|
2010-08-17 |
2018-04-06 |
3M创新有限公司 |
脂质化免疫反应调节剂化合物的组合物、制剂及方法
|
EA201390660A1
(ru)
|
2010-11-05 |
2013-11-29 |
Селекта Байосайенсиз, Инк. |
Модифицированные никотиновые соединения и связанные способы
|
EP3153180A1
(de)
|
2011-06-03 |
2017-04-12 |
3M Innovative Properties Company |
Heterobifunktionale binder mit polyethylenglykolsegmenten und daraus hergestellte immunantwort-modifizierende konjugate
|
CA2838158C
(en)
|
2011-06-03 |
2019-07-16 |
3M Innovative Properties Company |
Heterobifunctional linkers with polyethylene glycol segments and immune response modifier conjugates made therefrom
|
US20130023736A1
(en)
|
2011-07-21 |
2013-01-24 |
Stanley Dale Harpstead |
Systems for drug delivery and monitoring
|
CN109172819A
(zh)
|
2011-07-29 |
2019-01-11 |
西莱克塔生物科技公司 |
产生体液和细胞毒性t淋巴细胞(ctl)免疫应答的合成纳米载体
|
RU2737765C2
(ru)
|
2012-05-04 |
2020-12-02 |
Пфайзер Инк. |
Простатоассоциированные антигены и иммунотерапевтические схемы на основе вакцин
|
WO2014107663A2
(en)
|
2013-01-07 |
2014-07-10 |
The Trustees Of The University Of Pennsylvania |
Compositions and methods for treating cutaneous t cell lymphoma
|
ES2762631T3
(es)
|
2013-03-14 |
2020-05-25 |
Harvard College |
Composiciones a base de nanopartículas
|
US9919029B2
(en)
|
2013-07-26 |
2018-03-20 |
Inserm (Institut National De La Sante Et De La Recherche Medicale) |
Methods and pharmaceutical compositions for the treatment of bacterial infections
|
EP3094342A4
(de)
|
2014-01-15 |
2017-12-27 |
Nikolai Khodarev |
Antitumortherapie
|
US10821175B2
(en)
|
2014-02-25 |
2020-11-03 |
Merck Sharp & Dohme Corp. |
Lipid nanoparticle vaccine adjuvants and antigen delivery systems
|
MX2016014761A
(es)
|
2014-05-16 |
2017-05-25 |
Amgen Inc |
Ensayo para detectar poblaciones celulares linfocitos t colaboradores 1 (th1) y linfocitos t colaboradores (th2).
|
EA201692512A1
(ru)
|
2014-06-25 |
2017-07-31 |
Селекта Байосайенсиз, Инк. |
Способы и композиции для лечения синтетическими наноносителями и ингибиторами иммунной контрольной точки
|
US9884866B2
(en)
|
2014-09-08 |
2018-02-06 |
Regents Of The University Of Minnesota |
Immunomodulators and immunomodulator conjugates
|
WO2016044839A2
(en)
|
2014-09-19 |
2016-03-24 |
The Board Of Regents Of The University Of Texas System |
Compositions and methods for treating viral infections through stimulated innate immunity in combination with antiviral compounds
|
JP6956071B2
(ja)
|
2015-08-31 |
2021-10-27 |
スリーエム イノベイティブ プロパティズ カンパニー |
置換グアニジン基を含有するイミダゾ[4,5−c]環状化合物
|
EP3344622B1
(de)
|
2015-08-31 |
2021-07-07 |
3M Innovative Properties Company |
Guanidinsubstituierte kondensierte 1h-imidazo[4,5-c]pyridin-verbindungen, die zur behandlung viraler und neoplastischer krankheiten verwendet werden können.
|
WO2017059280A1
(en)
|
2015-10-02 |
2017-04-06 |
The University Of North Carolina At Chapel Hill |
Novel pan-tam inhibitors and mer/axl dual inhibitors
|
US10730871B2
(en)
|
2016-01-28 |
2020-08-04 |
Regents Of The University Of Minnesota |
Immunomodulators and immunomodulator conjugates
|
US11697851B2
(en)
|
2016-05-24 |
2023-07-11 |
The Regents Of The University Of California |
Early ovarian cancer detection diagnostic test based on mRNA isoforms
|
US10414779B2
(en)
|
2016-08-26 |
2019-09-17 |
3M Innovative Properties Company |
Fused [1,2]imidazo[4,5-C] ring compounds substituted with guanidino groups
|
JP7240311B2
(ja)
|
2016-08-30 |
2023-03-15 |
ダナ-ファーバー キャンサー インスティテュート, インコーポレイテッド |
薬物送達組成物およびその使用
|
CN110234401B
(zh)
|
2016-11-09 |
2024-03-01 |
德克萨斯大学系统董事会 |
用于适应性免疫调节的方法和组合物
|
WO2018160552A1
(en)
|
2017-03-01 |
2018-09-07 |
3M Innovative Properties Company |
IMIDAZO[4,5-c] RING COMPOUNDS CONTAINING GUANIDINE SUBSTITUTED BENZAMIDE GROUPS
|
EP3625231B1
(de)
|
2017-05-19 |
2022-07-20 |
Superb Wisdom Limited |
Derivate von resiquimod
|
EP3728255B1
(de)
*
|
2017-12-20 |
2022-01-26 |
3M Innovative Properties Company |
Amid-substituierte imidazo[4,5-c]chinolin-verbindungen mit verzweigtkettenverbindungsgruppe zur verwendung als immunreaktionsmodifikator
|
CN111788202B
(zh)
|
2018-02-28 |
2024-03-01 |
3M创新有限公司 |
具有N-1支链基团的经取代的咪唑并[4,5-c]喹啉化合物
|
JP7394790B2
(ja)
|
2018-05-24 |
2023-12-08 |
スリーエム イノベイティブ プロパティズ カンパニー |
N-1分枝状シクロアルキル置換イミダゾ[4,5-c]キノリン化合物、組成物、及び方法
|
CN113166143B
(zh)
|
2018-11-26 |
2024-06-04 |
舒万诺知识产权公司 |
N-1支链烷基醚取代的咪唑并[4,5-c]喹啉化合物、组合物和方法
|
WO2020245706A1
(en)
|
2019-06-06 |
2020-12-10 |
3M Innovative Properties Company |
N-1 branched alkyl substituted imidazo[4,5-c]quinoline compounds, compositions, and methods
|
EP3983408A1
(de)
|
2019-06-12 |
2022-04-20 |
3M Innovative Properties Company |
Phenethylsubstituierte imidazo[4,5-c]chinolin-verbindungen mit einer n-1-verzweigten gruppe
|
US12018082B2
(en)
*
|
2019-09-16 |
2024-06-25 |
The Regents Of The University Of California |
Methods and agents for treating infections
|
WO2021116420A1
(en)
|
2019-12-13 |
2021-06-17 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of tlr7 and/or tlr8 agonists for the treatment of leptospirosis
|