IL127915A - Preparations with many units of tramadol consisting of sustained release pills - Google Patents

Preparations with many units of tramadol consisting of sustained release pills

Info

Publication number
IL127915A
IL127915A IL12791597A IL12791597A IL127915A IL 127915 A IL127915 A IL 127915A IL 12791597 A IL12791597 A IL 12791597A IL 12791597 A IL12791597 A IL 12791597A IL 127915 A IL127915 A IL 127915A
Authority
IL
Israel
Prior art keywords
release
delayed
formulations according
pellets
pharmaceutical formulations
Prior art date
Application number
IL12791597A
Other languages
English (en)
Hebrew (he)
Other versions
IL127915A0 (en
Original Assignee
Asta Medica Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Ag filed Critical Asta Medica Ag
Publication of IL127915A0 publication Critical patent/IL127915A0/xx
Publication of IL127915A publication Critical patent/IL127915A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glanulating (AREA)
IL12791597A 1996-07-25 1997-07-19 Preparations with many units of tramadol consisting of sustained release pills IL127915A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19630035A DE19630035A1 (de) 1996-07-25 1996-07-25 Tramadol Multiple Unit Formulierungen
PCT/EP1997/003934 WO1998004249A2 (fr) 1996-07-25 1997-07-19 Formulations de tramadol a unites multiples

Publications (2)

Publication Number Publication Date
IL127915A0 IL127915A0 (en) 1999-11-30
IL127915A true IL127915A (en) 2001-08-08

Family

ID=7800815

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12791597A IL127915A (en) 1996-07-25 1997-07-19 Preparations with many units of tramadol consisting of sustained release pills

Country Status (29)

Country Link
US (2) US5955104A (fr)
EP (1) EP0917463B1 (fr)
JP (1) JP3631762B2 (fr)
KR (1) KR100474793B1 (fr)
CN (1) CN1111402C (fr)
AR (1) AR008002A1 (fr)
AT (1) ATE213408T1 (fr)
AU (1) AU737121B2 (fr)
BG (1) BG63708B1 (fr)
BR (1) BR9710761A (fr)
CA (1) CA2211284C (fr)
CZ (1) CZ296964B6 (fr)
DE (2) DE19630035A1 (fr)
DK (1) DK0917463T3 (fr)
EE (1) EE03742B1 (fr)
ES (1) ES2171268T3 (fr)
HK (1) HK1020876A1 (fr)
HU (1) HU227971B1 (fr)
IL (1) IL127915A (fr)
NO (1) NO324207B1 (fr)
NZ (1) NZ333822A (fr)
PL (1) PL188834B1 (fr)
PT (1) PT917463E (fr)
RU (1) RU2201223C2 (fr)
SK (1) SK285300B6 (fr)
TW (1) TW495363B (fr)
UA (1) UA52679C2 (fr)
WO (1) WO1998004249A2 (fr)
ZA (1) ZA975408B (fr)

Families Citing this family (57)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19630035A1 (de) * 1996-07-25 1998-01-29 Asta Medica Ag Tramadol Multiple Unit Formulierungen
US6197347B1 (en) * 1998-06-29 2001-03-06 Andrx Pharmaceuticals, Inc. Oral dosage for the controlled release of analgesic
US6312728B1 (en) * 1998-07-07 2001-11-06 Cascade Development, Inc. Sustained release pharmaceutical preparation
DE19901687B4 (de) * 1999-01-18 2006-06-01 Grünenthal GmbH Opioide Analgetika mit kontrollierter Wirkstofffreisetzung
DE19901686A1 (de) 1999-01-18 2000-07-20 Gruenenthal Gmbh Retardierte Tramadolzubereitungen mit einem lagerstabilen Freisetzungsprofil und Verfahren zu deren Herstellung
DE19940944B4 (de) * 1999-08-31 2006-10-12 Grünenthal GmbH Retardierte, orale, pharmazeutische Darreichungsformen
IL148411A0 (en) 1999-08-31 2002-09-12 Gruenenthal Chemie Delayed-action form of administration containing tramadol saccharinate
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
ES2374717T3 (es) 1999-10-29 2012-02-21 Euro-Celtique S.A. Formulaciones de hidrocodona de liberación controlada.
AR030557A1 (es) * 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
US6620431B1 (en) 2000-04-17 2003-09-16 Charles Signorino Shellac film coatings providing release at selected pH and method
WO2001096260A1 (fr) * 2000-06-14 2001-12-20 Chisso Corporation Procede de production de granules bioactifs enrobes
WO2002003914A2 (fr) * 2000-07-06 2002-01-17 Delsys Pharmaceutical Corporation Formulations ameliorees d'hormones thyroidiennes
WO2002036099A1 (fr) 2000-10-30 2002-05-10 Euro-Celtique S.A. Preparations d'hydrocodone a liberation lente
DE10108122A1 (de) 2001-02-21 2002-10-02 Gruenenthal Gmbh Arzneimittel auf Basis von Tramadol
WO2003009805A2 (fr) * 2001-07-23 2003-02-06 Brigham And Women's Hospital, Inc. Methodes analgesiques utilisant des ligands des recepteurs de l'endotheline
PE20030527A1 (es) 2001-10-24 2003-07-26 Gruenenthal Chemie Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen
ES2377729T3 (es) * 2002-02-21 2012-03-30 Valeant International (Barbados) Srl Formulaciones de liberación modificada de al menos una forma de tramadol
US20050182056A9 (en) * 2002-02-21 2005-08-18 Seth Pawan Modified release formulations of at least one form of tramadol
US8128957B1 (en) 2002-02-21 2012-03-06 Valeant International (Barbados) Srl Modified release compositions of at least one form of tramadol
CN1674873A (zh) * 2002-08-15 2005-09-28 欧罗赛铁克股份有限公司 药物组合物
DE50207738D1 (de) * 2002-11-27 2006-09-14 Oramon Arzneimittel Gmbh & Co Verfahren zur Herstellung von Pellets, enthaltend ein tri- oder tetracyclisches Antidepressivum sowie diese Pellets enthaltende pharmazeutische Zubereitungen
CN100500130C (zh) * 2003-01-23 2009-06-17 株式会社太平洋 缓释制剂及其制备方法
US20040202717A1 (en) 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
US20050053669A1 (en) * 2003-09-05 2005-03-10 Boehringer Ingelheim International Gmbh Administration form for the oral application of poorly soluble acidic and amphorteric drugs
DE10341414A1 (de) * 2003-09-05 2005-03-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Oral zu applizierende Darreichungsform für schwerlösliche saure und amphotere Wirkstoffe
WO2005034859A2 (fr) * 2003-10-03 2005-04-21 Elite Laboratories Inc. Formulations d'opioides a liberation prolongee et methode d'utilisation des formulations
US8163114B2 (en) * 2004-04-07 2012-04-24 New Jersey Institute Of Technology Netshape manufacturing processes and compositions
US20070224281A1 (en) * 2004-07-22 2007-09-27 Amorepacific Corporation Sustained-Release Preparations Containing Topiramate and the Producing Method Thereof
KR20080046751A (ko) 2004-09-01 2008-05-27 유로-셀띠끄 소시에떼 아노님 용량 비례적 정상 상태 Ｃａｖｅ및 ＡＵＣ를 갖고, 용량비례적 단일 용량 Ｃｍａｘ보다 작은 오피오이드성 제형
RU2401125C2 (ru) 2004-12-27 2010-10-10 Эйсай Ар Энд Ди Менеджмент Ко., Лтд. Способ стабилизации лекарственного средства против деменции
US20060246003A1 (en) * 2004-12-27 2006-11-02 Eisai Co. Ltd. Composition containing anti-dementia drug
US20070129402A1 (en) * 2004-12-27 2007-06-07 Eisai Research Institute Sustained release formulations
WO2007016948A1 (fr) * 2005-08-10 2007-02-15 Add Advanced Drug Delivery Technologies Ltd. Préparation orale à libération contrôlée
MX2008006037A (es) * 2005-11-10 2009-03-03 Circ Pharma Res And Dev Ltd Drogas para el sistema nervioso central para administracion una-vez-al-dia.
US20070185145A1 (en) * 2006-02-03 2007-08-09 Royds Robert B Pharmaceutical composition containing a central opioid agonist, a central opioid antagonist, and a peripheral opioid antagonist, and method for making the same
US20070190141A1 (en) * 2006-02-16 2007-08-16 Aaron Dely Extended release opiate composition
US20070264346A1 (en) * 2006-02-16 2007-11-15 Flamel Technologies Multimicroparticulate pharmaceutical forms for oral administration
US20070264335A1 (en) * 2006-05-09 2007-11-15 Sherman Bernard C Modified release tablets comprising tramadol
US20080181932A1 (en) * 2007-01-30 2008-07-31 Drugtech Corporation Compositions for oral delivery of pharmaceuticals
US10888521B2 (en) * 2007-03-02 2021-01-12 Farnam Companies, Inc. Sustained release compositions using wax-like materials
BRPI0815387B8 (pt) 2007-08-13 2021-05-25 Abuse Deterrent Pharmaceutical Llc composição farmacêutica, método para fazer uma composição farmacêutica e uso da composição farmacêutica
CN101095666B (zh) * 2007-08-14 2010-10-06 石药集团欧意药业有限公司 一种盐酸曲马多缓释片剂及其制备方法
CZ300468B6 (cs) * 2007-09-20 2009-05-27 Zentiva, A. S Léková forma obsahující tramadol s kontrolovaným uvolnováním po dobu 24 hodin a zpusob její prípravy
WO2009087690A2 (fr) * 2008-01-11 2009-07-16 Jubilant Organosys Limited Composition pharmaceutique multiparticulaire à libération prolongée de carbamazépine et son procédé de fabrication
US20100003322A1 (en) * 2008-07-03 2010-01-07 Lai Felix S Enteric coated hydrophobic matrix formulation
JP5608653B2 (ja) * 2008-09-04 2014-10-15 ファーナム・カンパニーズ・インコーポレーテッド チュアブルな徐放性製剤
FR2938431B1 (fr) * 2008-11-14 2013-12-20 Debregeas Et Associes Pharma Nouvelle composition a base d'acide gamma-hydroxybutyrique
MX339852B (es) 2008-11-18 2016-06-15 Ucb Pharma Sa Formulaciones de liberacion prolongada que comprenden un derivado de 2-oxo-1-pirrolidina.
US20100233259A1 (en) * 2008-12-12 2010-09-16 Pascal Grenier Dosage form of ropinirole
FR2949062B1 (fr) 2009-08-12 2011-09-02 Debregeas Et Associes Pharma Nouvelles formulations pharmaceutiques contre le mesusage des medicaments
FR2949061B1 (fr) 2009-08-12 2013-04-19 Debregeas Et Associes Pharma Microgranules flottants
CA2801620A1 (fr) 2010-07-06 2012-01-12 Gruenenthal Gmbh Nouvelles formes posologiques a retention gastrique comprenant un analogue de gaba et un opioide
CA2877774C (fr) 2012-07-12 2017-07-18 Mallinckrodt Llc Compositions pharmaceutiques de dissuasion d'abus a liberation prolongee
US10420726B2 (en) 2013-03-15 2019-09-24 Inspirion Delivery Sciences, Llc Abuse deterrent compositions and methods of use
US10729685B2 (en) 2014-09-15 2020-08-04 Ohemo Life Sciences Inc. Orally administrable compositions and methods of deterring abuse by intranasal administration
IT201800011125A1 (it) * 2018-12-14 2020-06-14 Dpl Pharma S P A Composizioni farmaceutiche orali solide comprendenti matrici monolitiche complesse per la somministrazione cronotropica di medicamenti nel tratto gastroenterico

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US4415547A (en) * 1982-06-14 1983-11-15 Sterling Drug Inc. Sustained-release pharmaceutical tablet and process for preparation thereof
JPS62103012A (ja) * 1985-10-23 1987-05-13 Eisai Co Ltd 多重顆粒
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
US5344657A (en) * 1988-04-27 1994-09-06 Elf Sanofi Microbeads of diltiazem, a process for their manufacture and a substained-release pharmaceutical composition containing them
US5260072A (en) * 1990-08-30 1993-11-09 Mcneil-Ppc, Inc. Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
AU661723B2 (en) * 1991-10-30 1995-08-03 Mcneilab, Inc. Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5395626A (en) * 1994-03-23 1995-03-07 Ortho Pharmaceutical Corporation Multilayered controlled release pharmaceutical dosage form
US5411745A (en) * 1994-05-25 1995-05-02 Euro-Celtique, S.A. Powder-layered morphine sulfate formulations
DE4428444A1 (de) * 1994-08-11 1996-02-15 Dresden Arzneimittel Verwendung von Selegilin zur Behandlung von epileptischen Erkrankungen
US5567441A (en) * 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
DE19630035A1 (de) * 1996-07-25 1998-01-29 Asta Medica Ag Tramadol Multiple Unit Formulierungen

Also Published As

Publication number Publication date
TW495363B (en) 2002-07-21
CN1111402C (zh) 2003-06-18
HUP9903053A3 (en) 2000-02-28
KR20000029530A (ko) 2000-05-25
SK9899A3 (en) 1999-09-10
AR008002A1 (es) 1999-11-24
CN1226824A (zh) 1999-08-25
PT917463E (pt) 2002-07-31
CZ296964B6 (cs) 2006-08-16
SK285300B6 (sk) 2006-10-05
CZ18599A3 (cs) 1999-04-14
CA2211284C (fr) 2001-10-23
UA52679C2 (uk) 2003-01-15
HUP9903053A2 (hu) 2000-01-28
EP0917463B1 (fr) 2002-02-20
ES2171268T3 (es) 2002-09-01
NZ333822A (en) 1999-11-29
CA2211284A1 (fr) 1998-01-25
NO990261L (no) 1999-01-21
NO990261D0 (no) 1999-01-21
BR9710761A (pt) 1999-08-17
PL331387A1 (en) 1999-07-05
IL127915A0 (en) 1999-11-30
BG103158A (en) 1999-08-31
AU737121B2 (en) 2001-08-09
EE03742B1 (et) 2002-06-17
KR100474793B1 (ko) 2005-03-08
RU2201223C2 (ru) 2003-03-27
JP3631762B2 (ja) 2005-03-23
DE59706441D1 (de) 2002-03-28
HK1020876A1 (en) 2000-05-26
BG63708B1 (bg) 2002-10-31
US5955104A (en) 1999-09-21
ZA975408B (en) 1998-01-05
US6436438B1 (en) 2002-08-20
NO324207B1 (no) 2007-09-10
JP2000515871A (ja) 2000-11-28
AU3849197A (en) 1998-02-20
WO1998004249A3 (fr) 1998-04-30
PL188834B1 (pl) 2005-04-29
EE9900031A (et) 1999-08-16
ATE213408T1 (de) 2002-03-15
EP0917463A2 (fr) 1999-05-26
DE19630035A1 (de) 1998-01-29
HU227971B1 (en) 2012-07-30
WO1998004249A2 (fr) 1998-02-05
DK0917463T3 (da) 2002-06-10

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