HK1020876A1 - Tramadol multiple unit formulations - Google Patents

Tramadol multiple unit formulations

Info

Publication number
HK1020876A1
HK1020876A1 HK99106029A HK99106029A HK1020876A1 HK 1020876 A1 HK1020876 A1 HK 1020876A1 HK 99106029 A HK99106029 A HK 99106029A HK 99106029 A HK99106029 A HK 99106029A HK 1020876 A1 HK1020876 A1 HK 1020876A1
Authority
HK
Hong Kong
Prior art keywords
multiple unit
unit formulations
tramadol
tramadol multiple
formulations
Prior art date
Application number
HK99106029A
Other languages
English (en)
Inventor
Helmut Momberger
Marc Raber
Dieter Kuhn
Wolfgang Schmid
Original Assignee
Viatris Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Viatris Gmbh filed Critical Viatris Gmbh
Publication of HK1020876A1 publication Critical patent/HK1020876A1/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glanulating (AREA)
HK99106029A 1996-07-25 1999-12-22 Tramadol multiple unit formulations HK1020876A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19630035A DE19630035A1 (de) 1996-07-25 1996-07-25 Tramadol Multiple Unit Formulierungen
PCT/EP1997/003934 WO1998004249A2 (de) 1996-07-25 1997-07-19 Tramadol multiple unit formulierungen

Publications (1)

Publication Number Publication Date
HK1020876A1 true HK1020876A1 (en) 2000-05-26

Family

ID=7800815

Family Applications (1)

Application Number Title Priority Date Filing Date
HK99106029A HK1020876A1 (en) 1996-07-25 1999-12-22 Tramadol multiple unit formulations

Country Status (29)

Country Link
US (2) US5955104A (xx)
EP (1) EP0917463B1 (xx)
JP (1) JP3631762B2 (xx)
KR (1) KR100474793B1 (xx)
CN (1) CN1111402C (xx)
AR (1) AR008002A1 (xx)
AT (1) ATE213408T1 (xx)
AU (1) AU737121B2 (xx)
BG (1) BG63708B1 (xx)
BR (1) BR9710761A (xx)
CA (1) CA2211284C (xx)
CZ (1) CZ296964B6 (xx)
DE (2) DE19630035A1 (xx)
DK (1) DK0917463T3 (xx)
EE (1) EE03742B1 (xx)
ES (1) ES2171268T3 (xx)
HK (1) HK1020876A1 (xx)
HU (1) HU227971B1 (xx)
IL (1) IL127915A (xx)
NO (1) NO324207B1 (xx)
NZ (1) NZ333822A (xx)
PL (1) PL188834B1 (xx)
PT (1) PT917463E (xx)
RU (1) RU2201223C2 (xx)
SK (1) SK285300B6 (xx)
TW (1) TW495363B (xx)
UA (1) UA52679C2 (xx)
WO (1) WO1998004249A2 (xx)
ZA (1) ZA975408B (xx)

Families Citing this family (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19630035A1 (de) * 1996-07-25 1998-01-29 Asta Medica Ag Tramadol Multiple Unit Formulierungen
US6197347B1 (en) * 1998-06-29 2001-03-06 Andrx Pharmaceuticals, Inc. Oral dosage for the controlled release of analgesic
US6312728B1 (en) * 1998-07-07 2001-11-06 Cascade Development, Inc. Sustained release pharmaceutical preparation
DE19901686A1 (de) 1999-01-18 2000-07-20 Gruenenthal Gmbh Retardierte Tramadolzubereitungen mit einem lagerstabilen Freisetzungsprofil und Verfahren zu deren Herstellung
DE19901687B4 (de) * 1999-01-18 2006-06-01 Grünenthal GmbH Opioide Analgetika mit kontrollierter Wirkstofffreisetzung
DE19940944B4 (de) * 1999-08-31 2006-10-12 Grünenthal GmbH Retardierte, orale, pharmazeutische Darreichungsformen
JP2003508430A (ja) 1999-08-31 2003-03-04 グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング トラマドールサッカリナートを含有する徐放性投薬形
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
MXPA02004293A (es) * 1999-10-29 2002-10-31 Euro Celtique Sa Formulaciones de hidrocodona de liberacion controlada..
AR030557A1 (es) * 2000-04-14 2003-08-27 Jagotec Ag Una tableta en multicapa de liberacion controlada y metodo de tratamiento
US6620431B1 (en) 2000-04-17 2003-09-16 Charles Signorino Shellac film coatings providing release at selected pH and method
US20030157247A1 (en) * 2000-06-14 2003-08-21 Yoshiro Chikami Method for producing coated bioactive granule
CA2415080A1 (en) * 2000-07-06 2002-01-17 Delsys Pharmaceutical Corporation Improved thyroid hormone formulations
CN100518827C (zh) 2000-10-30 2009-07-29 欧罗赛铁克股份有限公司 控释氢可酮制剂
DE10108122A1 (de) 2001-02-21 2002-10-02 Gruenenthal Gmbh Arzneimittel auf Basis von Tramadol
AU2002355266A1 (en) * 2001-07-23 2003-02-17 Brigham And Women's Hospital, Inc. Analgesic methods using endothelin receptor ligands
PE20030527A1 (es) 2001-10-24 2003-07-26 Gruenenthal Chemie Formulacion farmaceutica con liberacion retardada que contiene 3-(3-dimetilamino-1-etil-2-metil-propil) fenol o una sal farmaceuticamente aceptable del mismo y tabletas para administracion oral que la contienen
ES2627842T3 (es) * 2002-02-21 2017-07-31 Valeant Pharmaceuticals Luxembourg S.À.R.L. Formas de dosificación de liberación controlada
US8128957B1 (en) * 2002-02-21 2012-03-06 Valeant International (Barbados) Srl Modified release compositions of at least one form of tramadol
US20050182056A9 (en) * 2002-02-21 2005-08-18 Seth Pawan Modified release formulations of at least one form of tramadol
SI1542658T1 (sl) * 2002-08-15 2011-04-29 Euro Celtique Sa Farmacevtski sestavki, ki obsegajo opioidni analgetik
DK1424068T3 (da) * 2002-11-27 2006-11-27 Oramon Arzneimittel Gmbh & Co Fremgangsmåde til fremstilling af pellets indeholdende et tri- eller tetra-cyklisk antidepressivum samt farmaceutiske tilberedninger indeholdende disse pellets
CA2509259A1 (en) * 2003-01-23 2004-08-05 Amorepacific Corporation Sustained-release preparations and method for producing the same
US20040202717A1 (en) 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
US20050053669A1 (en) * 2003-09-05 2005-03-10 Boehringer Ingelheim International Gmbh Administration form for the oral application of poorly soluble acidic and amphorteric drugs
DE10341414A1 (de) * 2003-09-05 2005-03-31 Boehringer Ingelheim Pharma Gmbh & Co. Kg Oral zu applizierende Darreichungsform für schwerlösliche saure und amphotere Wirkstoffe
US20050074493A1 (en) * 2003-10-03 2005-04-07 Mehta Atul M. Extended release formulations of opioids and method of use thereof
US8163114B2 (en) * 2004-04-07 2012-04-24 New Jersey Institute Of Technology Netshape manufacturing processes and compositions
CA2572928A1 (en) * 2004-07-22 2006-02-26 Amorepacific Corporation Sustained-release preparations containing topiramate and the producing method thereof
MX2007002135A (es) 2004-09-01 2007-04-02 Euro Celtique Sa Formas farmaceuticas de opioide que tienen una cprom y un auc en el estado estacionario proporcional a la dosis y una cmax de la dosis unica menor que la proporcional a la dosis.
US20070129402A1 (en) * 2004-12-27 2007-06-07 Eisai Research Institute Sustained release formulations
EP1830886B1 (en) 2004-12-27 2016-04-13 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
US20060246003A1 (en) * 2004-12-27 2006-11-02 Eisai Co. Ltd. Composition containing anti-dementia drug
WO2007016948A1 (de) * 2005-08-10 2007-02-15 Add Advanced Drug Delivery Technologies Ltd. Orales präparat mit kontrollierter freisetzung
CA2628031C (en) * 2005-11-10 2013-03-05 Circ Pharma Research And Development Limited Once-daily administration of central nervous system drugs
US20070185145A1 (en) * 2006-02-03 2007-08-09 Royds Robert B Pharmaceutical composition containing a central opioid agonist, a central opioid antagonist, and a peripheral opioid antagonist, and method for making the same
US20070264346A1 (en) * 2006-02-16 2007-11-15 Flamel Technologies Multimicroparticulate pharmaceutical forms for oral administration
US20070190141A1 (en) * 2006-02-16 2007-08-16 Aaron Dely Extended release opiate composition
US20070264335A1 (en) * 2006-05-09 2007-11-15 Sherman Bernard C Modified release tablets comprising tramadol
US20080181932A1 (en) * 2007-01-30 2008-07-31 Drugtech Corporation Compositions for oral delivery of pharmaceuticals
EP2144599B1 (en) * 2007-03-02 2010-08-04 Farnam Companies, Inc. Sustained release pellets comprising wax-like material
CN101801350A (zh) 2007-08-13 2010-08-11 阿巴斯迪特宁医药有限公司 抗滥用药物、使用方法和制备方法
CN101095666B (zh) * 2007-08-14 2010-10-06 石药集团欧意药业有限公司 一种盐酸曲马多缓释片剂及其制备方法
CZ300468B6 (cs) * 2007-09-20 2009-05-27 Zentiva, A. S Léková forma obsahující tramadol s kontrolovaným uvolnováním po dobu 24 hodin a zpusob její prípravy
US20100285119A1 (en) * 2008-01-11 2010-11-11 Jubilant Organosys Ltd. Multiparticulate Extended Release Pharmaceutical Composition Of Carbamazepine And Process For Manufacturing The Same
US20100003322A1 (en) * 2008-07-03 2010-01-07 Lai Felix S Enteric coated hydrophobic matrix formulation
JP5608653B2 (ja) * 2008-09-04 2014-10-15 ファーナム・カンパニーズ・インコーポレーテッド チュアブルな徐放性製剤
FR2938431B1 (fr) * 2008-11-14 2013-12-20 Debregeas Et Associes Pharma Nouvelle composition a base d'acide gamma-hydroxybutyrique
MX339852B (es) 2008-11-18 2016-06-15 Ucb Pharma Sa Formulaciones de liberacion prolongada que comprenden un derivado de 2-oxo-1-pirrolidina.
US20100233259A1 (en) * 2008-12-12 2010-09-16 Pascal Grenier Dosage form of ropinirole
FR2949061B1 (fr) 2009-08-12 2013-04-19 Debregeas Et Associes Pharma Microgranules flottants
FR2949062B1 (fr) 2009-08-12 2011-09-02 Debregeas Et Associes Pharma Nouvelles formulations pharmaceutiques contre le mesusage des medicaments
WO2012003968A1 (en) 2010-07-06 2012-01-12 Grünenthal GmbH Novel gastro- retentive dosage forms comprising a gaba analog and an opioid
US9730885B2 (en) 2012-07-12 2017-08-15 Mallinckrodt Llc Extended release, abuse deterrent pharmaceutical compositions
CA2907428A1 (en) 2013-03-15 2014-09-18 Inspirion Delivery Technologies, Llc Abuse deterrent compositions and methods of use
US10729685B2 (en) 2014-09-15 2020-08-04 Ohemo Life Sciences Inc. Orally administrable compositions and methods of deterring abuse by intranasal administration

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4415547A (en) * 1982-06-14 1983-11-15 Sterling Drug Inc. Sustained-release pharmaceutical tablet and process for preparation thereof
JPS62103012A (ja) * 1985-10-23 1987-05-13 Eisai Co Ltd 多重顆粒
US5026560A (en) * 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
US5344657A (en) * 1988-04-27 1994-09-06 Elf Sanofi Microbeads of diltiazem, a process for their manufacture and a substained-release pharmaceutical composition containing them
US5260072A (en) * 1990-08-30 1993-11-09 Mcneil-Ppc, Inc. Rotogranulations and taste masking coatings for preparation of chewable pharmaceutical tablets
AU661723B2 (en) * 1991-10-30 1995-08-03 Mcneilab, Inc. Composition comprising a tramadol material and a non-steroidal anti-inflammatory drug
US5478577A (en) * 1993-11-23 1995-12-26 Euroceltique, S.A. Method of treating pain by administering 24 hour oral opioid formulations exhibiting rapid rate of initial rise of plasma drug level
US5395626A (en) * 1994-03-23 1995-03-07 Ortho Pharmaceutical Corporation Multilayered controlled release pharmaceutical dosage form
US5411745A (en) * 1994-05-25 1995-05-02 Euro-Celtique, S.A. Powder-layered morphine sulfate formulations
DE4428444A1 (de) * 1994-08-11 1996-02-15 Dresden Arzneimittel Verwendung von Selegilin zur Behandlung von epileptischen Erkrankungen
US5567441A (en) * 1995-03-24 1996-10-22 Andrx Pharmaceuticals Inc. Diltiazem controlled release formulation
DE19630035A1 (de) * 1996-07-25 1998-01-29 Asta Medica Ag Tramadol Multiple Unit Formulierungen

Also Published As

Publication number Publication date
PL331387A1 (en) 1999-07-05
IL127915A (en) 2001-08-08
BG63708B1 (bg) 2002-10-31
SK285300B6 (sk) 2006-10-05
NO324207B1 (no) 2007-09-10
NZ333822A (en) 1999-11-29
HU227971B1 (en) 2012-07-30
EP0917463B1 (de) 2002-02-20
PT917463E (pt) 2002-07-31
CN1226824A (zh) 1999-08-25
HUP9903053A3 (en) 2000-02-28
AU3849197A (en) 1998-02-20
SK9899A3 (en) 1999-09-10
NO990261D0 (no) 1999-01-21
CN1111402C (zh) 2003-06-18
AR008002A1 (es) 1999-11-24
JP3631762B2 (ja) 2005-03-23
EE9900031A (et) 1999-08-16
BR9710761A (pt) 1999-08-17
NO990261L (no) 1999-01-21
UA52679C2 (uk) 2003-01-15
IL127915A0 (en) 1999-11-30
KR20000029530A (ko) 2000-05-25
AU737121B2 (en) 2001-08-09
WO1998004249A3 (de) 1998-04-30
CA2211284C (en) 2001-10-23
TW495363B (en) 2002-07-21
US5955104A (en) 1999-09-21
ZA975408B (en) 1998-01-05
BG103158A (en) 1999-08-31
PL188834B1 (pl) 2005-04-29
EE03742B1 (et) 2002-06-17
ATE213408T1 (de) 2002-03-15
ES2171268T3 (es) 2002-09-01
CZ296964B6 (cs) 2006-08-16
HUP9903053A2 (hu) 2000-01-28
EP0917463A2 (de) 1999-05-26
KR100474793B1 (ko) 2005-03-08
DE19630035A1 (de) 1998-01-29
CZ18599A3 (cs) 1999-04-14
JP2000515871A (ja) 2000-11-28
DE59706441D1 (de) 2002-03-28
US6436438B1 (en) 2002-08-20
CA2211284A1 (en) 1998-01-25
DK0917463T3 (da) 2002-06-10
WO1998004249A2 (de) 1998-02-05
RU2201223C2 (ru) 2003-03-27

Similar Documents

Publication Publication Date Title
HK1020876A1 (en) Tramadol multiple unit formulations
GB9715751D0 (en) Formulations
EP0888151A4 (en) MECHANICAL BRAKE FOR RECALL
SG99290A1 (en) Calcilytic compounds
ZA9811461B (en) New formulation
ZA9710601B (en) Novel formulation
ZA985669B (en) New formulation
GB9621990D0 (en) Use
PL329244A1 (en) Maize-selective herbicide
ZA976592B (en) Formulation
GB9605948D0 (en) Novel formulations
GB9611192D0 (en) Use
GB9624115D0 (en) Formulations
GB9625028D0 (en) Mops
GB9406050D0 (en) Formulations
GB9408419D0 (en) Formulations
GB9409464D0 (en) Formulations
GB9404989D0 (en) Lipomimetric formulation
GB9417041D0 (en) Improved formulations
GB9419921D0 (en) Improved formulations
GB9703099D0 (en) Formulations
GB9703101D0 (en) Formulations
GB9704521D0 (en) Formulations
GB9703100D0 (en) Formulations
GB9620849D0 (en) Glyphosate formulations

Legal Events

Date Code Title Description
PF Patent in force
PE Patent expired

Effective date: 20170718