HUP9903053A2 - Tramadol Multiple Unit készítmények és eljárás ezek előállítására - Google Patents

Tramadol Multiple Unit készítmények és eljárás ezek előállítására

Info

Publication number
HUP9903053A2
HUP9903053A2 HU9903053A HUP9903053A HUP9903053A2 HU P9903053 A2 HUP9903053 A2 HU P9903053A2 HU 9903053 A HU9903053 A HU 9903053A HU P9903053 A HUP9903053 A HU P9903053A HU P9903053 A2 HUP9903053 A2 HU P9903053A2
Authority
HU
Hungary
Prior art keywords
multiple unit
producing
unit formulations
tramadol
tramadol multiple
Prior art date
Application number
HU9903053A
Other languages
English (en)
Inventor
Dieter Kuhn
Helmut Momberger
Marc Raber
Wolfgang Schmid
Original Assignee
Asta Medica Aktiengesellschaft
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Asta Medica Aktiengesellschaft filed Critical Asta Medica Aktiengesellschaft
Publication of HUP9903053A2 publication Critical patent/HUP9903053A2/hu
Publication of HUP9903053A3 publication Critical patent/HUP9903053A3/hu
Publication of HU227971B1 publication Critical patent/HU227971B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • Pain & Pain Management (AREA)
  • Emergency Medicine (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Rheumatology (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Glanulating (AREA)

Abstract

A találmány tárgyát többszörös egységű (Műltiple Unit), retardgyógyszerkészítmények képezik, melyek egyes, azőnősan vagykülönbözőképen késleltetett hatású tramadőlal vagy ennek fiziőlógiásanelviselhető sójával bevőnt semleges kiindűlási anyagból állószemcséket tartalmaznak. E szemcsék legalább egy vagy több,gyógyszerészetileg elfőgadható hatóanyag-felszabadűlást szabályőzómembránréteggel vannak bevőnva. A többszörös egységű készítményekkapszűlák vagy tabletták főrmájában adagőlhatók, és hatásűk 12 vagy 24órán át tart. ŕ
HU9903053A 1996-07-25 1997-07-19 Tramadol multiple unit formulations and process for producing them HU227971B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19630035A DE19630035A1 (de) 1996-07-25 1996-07-25 Tramadol Multiple Unit Formulierungen
PCT/EP1997/003934 WO1998004249A2 (de) 1996-07-25 1997-07-19 Tramadol multiple unit formulierungen

Publications (3)

Publication Number Publication Date
HUP9903053A2 true HUP9903053A2 (hu) 2000-01-28
HUP9903053A3 HUP9903053A3 (en) 2000-02-28
HU227971B1 HU227971B1 (en) 2012-07-30

Family

ID=7800815

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9903053A HU227971B1 (en) 1996-07-25 1997-07-19 Tramadol multiple unit formulations and process for producing them

Country Status (29)

Country Link
US (2) US5955104A (hu)
EP (1) EP0917463B1 (hu)
JP (1) JP3631762B2 (hu)
KR (1) KR100474793B1 (hu)
CN (1) CN1111402C (hu)
AR (1) AR008002A1 (hu)
AT (1) ATE213408T1 (hu)
AU (1) AU737121B2 (hu)
BG (1) BG63708B1 (hu)
BR (1) BR9710761A (hu)
CA (1) CA2211284C (hu)
CZ (1) CZ296964B6 (hu)
DE (2) DE19630035A1 (hu)
DK (1) DK0917463T3 (hu)
EE (1) EE03742B1 (hu)
ES (1) ES2171268T3 (hu)
HK (1) HK1020876A1 (hu)
HU (1) HU227971B1 (hu)
IL (1) IL127915A (hu)
NO (1) NO324207B1 (hu)
NZ (1) NZ333822A (hu)
PL (1) PL188834B1 (hu)
PT (1) PT917463E (hu)
RU (1) RU2201223C2 (hu)
SK (1) SK285300B6 (hu)
TW (1) TW495363B (hu)
UA (1) UA52679C2 (hu)
WO (1) WO1998004249A2 (hu)
ZA (1) ZA975408B (hu)

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DE19901686A1 (de) 1999-01-18 2000-07-20 Gruenenthal Gmbh Retardierte Tramadolzubereitungen mit einem lagerstabilen Freisetzungsprofil und Verfahren zu deren Herstellung
DE19901687B4 (de) * 1999-01-18 2006-06-01 Grünenthal GmbH Opioide Analgetika mit kontrollierter Wirkstofffreisetzung
DE19940944B4 (de) * 1999-08-31 2006-10-12 Grünenthal GmbH Retardierte, orale, pharmazeutische Darreichungsformen
CA2388560A1 (en) 1999-08-31 2001-03-08 Grunenthal Gmbh Sustained-release form of administration containing tramadol saccharinate
US10179130B2 (en) 1999-10-29 2019-01-15 Purdue Pharma L.P. Controlled release hydrocodone formulations
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CA2509259A1 (en) 2003-01-23 2004-08-05 Amorepacific Corporation Sustained-release preparations and method for producing the same
US20040202717A1 (en) 2003-04-08 2004-10-14 Mehta Atul M. Abuse-resistant oral dosage forms and method of use thereof
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US20050053669A1 (en) * 2003-09-05 2005-03-10 Boehringer Ingelheim International Gmbh Administration form for the oral application of poorly soluble acidic and amphorteric drugs
CA2541371C (en) * 2003-10-03 2014-12-16 Atul M. Mehta Extended release formulations of opioids and method of use thereof
US8163114B2 (en) * 2004-04-07 2012-04-24 New Jersey Institute Of Technology Netshape manufacturing processes and compositions
JP2008507508A (ja) * 2004-07-22 2008-03-13 株式會社アモーレパシフィック トピラメート徐放性製剤及びその製造方法
WO2006028830A2 (en) 2004-09-01 2006-03-16 Euro-Celtique S.A. Opioid dosage forms having dose proportional steady state cave and auc and less than dose proportional single dose cmax
US20070129402A1 (en) * 2004-12-27 2007-06-07 Eisai Research Institute Sustained release formulations
US8481565B2 (en) 2004-12-27 2013-07-09 Eisai R&D Management Co., Ltd. Method for stabilizing anti-dementia drug
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US20070264346A1 (en) * 2006-02-16 2007-11-15 Flamel Technologies Multimicroparticulate pharmaceutical forms for oral administration
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WO2008094877A2 (en) * 2007-01-30 2008-08-07 Drugtech Corporation Compositions for oral delivery of pharmaceuticals
ATE476176T1 (de) * 2007-03-02 2010-08-15 Farnam Co Inc Wachsähnliches material enthaltende tabletten mit verzögerter freisetzung
ES2692437T3 (es) * 2007-08-13 2018-12-03 Abuse Deterrent Pharmaceutical Llc Fármacos resistentes al abuso, método de uso y método de preparación
CN101095666B (zh) * 2007-08-14 2010-10-06 石药集团欧意药业有限公司 一种盐酸曲马多缓释片剂及其制备方法
CZ300468B6 (cs) * 2007-09-20 2009-05-27 Zentiva, A. S Léková forma obsahující tramadol s kontrolovaným uvolnováním po dobu 24 hodin a zpusob její prípravy
WO2009087690A2 (en) * 2008-01-11 2009-07-16 Jubilant Organosys Limited Multiparticulate extended release pharmaceutical composition of carbamazepine and process for manufacturing the same
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FR2938431B1 (fr) * 2008-11-14 2013-12-20 Debregeas Et Associes Pharma Nouvelle composition a base d'acide gamma-hydroxybutyrique
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US20100233259A1 (en) * 2008-12-12 2010-09-16 Pascal Grenier Dosage form of ropinirole
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Also Published As

Publication number Publication date
HK1020876A1 (en) 2000-05-26
WO1998004249A2 (de) 1998-02-05
AU737121B2 (en) 2001-08-09
TW495363B (en) 2002-07-21
BG63708B1 (bg) 2002-10-31
PL331387A1 (en) 1999-07-05
SK285300B6 (sk) 2006-10-05
PT917463E (pt) 2002-07-31
RU2201223C2 (ru) 2003-03-27
EP0917463B1 (de) 2002-02-20
AU3849197A (en) 1998-02-20
JP3631762B2 (ja) 2005-03-23
US6436438B1 (en) 2002-08-20
NO990261D0 (no) 1999-01-21
CN1226824A (zh) 1999-08-25
CA2211284A1 (en) 1998-01-25
JP2000515871A (ja) 2000-11-28
KR20000029530A (ko) 2000-05-25
WO1998004249A3 (de) 1998-04-30
EE9900031A (et) 1999-08-16
HU227971B1 (en) 2012-07-30
NO990261L (no) 1999-01-21
EE03742B1 (et) 2002-06-17
ATE213408T1 (de) 2002-03-15
IL127915A0 (en) 1999-11-30
CA2211284C (en) 2001-10-23
US5955104A (en) 1999-09-21
ZA975408B (en) 1998-01-05
CZ18599A3 (cs) 1999-04-14
ES2171268T3 (es) 2002-09-01
DE59706441D1 (de) 2002-03-28
UA52679C2 (uk) 2003-01-15
PL188834B1 (pl) 2005-04-29
CN1111402C (zh) 2003-06-18
DE19630035A1 (de) 1998-01-29
BR9710761A (pt) 1999-08-17
DK0917463T3 (da) 2002-06-10
EP0917463A2 (de) 1999-05-26
HUP9903053A3 (en) 2000-02-28
IL127915A (en) 2001-08-08
BG103158A (en) 1999-08-31
KR100474793B1 (ko) 2005-03-08
CZ296964B6 (cs) 2006-08-16
NZ333822A (en) 1999-11-29
AR008002A1 (es) 1999-11-24
SK9899A3 (en) 1999-09-10
NO324207B1 (no) 2007-09-10

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Legal Events

Date Code Title Description
HC9A Change of name, address

Owner name: MEDA PHARMA GMBH & CO. KG, DE

Free format text: FORMER OWNER(S): ASTA MEDICA HEALTH PRODUCTS GMBH & CO. KG, DE; ASTA MEDICA AKTIENGESELLSCHAFT, DE; VIATRIS GMBH & CO. KG, DE; VIATRIS GMBH & CO. KG, DE