IL127487A - Use of thiazolidinone derivatives for the preparation of drugs for the treatment of neurodegenerative diseases - Google Patents

Use of thiazolidinone derivatives for the preparation of drugs for the treatment of neurodegenerative diseases

Info

Publication number
IL127487A
IL127487A IL12748797A IL12748797A IL127487A IL 127487 A IL127487 A IL 127487A IL 12748797 A IL12748797 A IL 12748797A IL 12748797 A IL12748797 A IL 12748797A IL 127487 A IL127487 A IL 127487A
Authority
IL
Israel
Prior art keywords
thiazolidinone
eae
neurodegenerative disorders
cells
disease
Prior art date
Application number
IL12748797A
Other languages
English (en)
Hebrew (he)
Other versions
IL127487A0 (en
Original Assignee
Warner Lambert Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co filed Critical Warner Lambert Co
Publication of IL127487A0 publication Critical patent/IL127487A0/xx
Publication of IL127487A publication Critical patent/IL127487A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
IL12748797A 1996-07-11 1997-07-01 Use of thiazolidinone derivatives for the preparation of drugs for the treatment of neurodegenerative diseases IL127487A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US2157196P 1996-07-11 1996-07-11
PCT/US1997/011586 WO1998002160A1 (en) 1996-07-11 1997-07-01 Method for treating and preventing neurodegenerative disorders by administering a thiazolidinone

Publications (2)

Publication Number Publication Date
IL127487A0 IL127487A0 (en) 1999-10-28
IL127487A true IL127487A (en) 2002-04-21

Family

ID=21804973

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12748797A IL127487A (en) 1996-07-11 1997-07-01 Use of thiazolidinone derivatives for the preparation of drugs for the treatment of neurodegenerative diseases

Country Status (23)

Country Link
US (1) US5912259A (ja)
EP (1) EP0914122B1 (ja)
JP (1) JP2001508028A (ja)
KR (1) KR20000023683A (ja)
CN (1) CN1145481C (ja)
AT (1) ATE250416T1 (ja)
AU (1) AU726664B2 (ja)
BR (1) BR9710467A (ja)
CA (1) CA2255073A1 (ja)
CO (1) CO4940509A1 (ja)
DE (1) DE69725147T2 (ja)
DK (1) DK0914122T3 (ja)
ES (1) ES2205247T3 (ja)
HK (1) HK1020533A1 (ja)
HR (1) HRP970362A2 (ja)
IL (1) IL127487A (ja)
NO (1) NO990076D0 (ja)
NZ (1) NZ332763A (ja)
PL (1) PL331049A1 (ja)
PT (1) PT914122E (ja)
TR (1) TR199900040T2 (ja)
WO (1) WO1998002160A1 (ja)
ZA (1) ZA976142B (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2003247514A1 (en) * 2002-06-11 2003-12-22 Roy Ogle Meningeal-derived stem cells
WO2009137109A1 (en) * 2008-05-08 2009-11-12 Rutgers, The State University Endorphin therapy compositions and methods

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL79648A (en) * 1985-08-09 1991-12-12 Lilly Co Eli Pharmaceutical anti-inflammatory and ischemia preventing compositions containing di-t-butylphenol derivatives,some such novel compounds and process for their preparation
CA2013599C (en) * 1989-04-07 1999-11-16 Jill A. Panetta Aryl-substituted rhodanine derivatives
US5143928A (en) * 1990-03-27 1992-09-01 Warner-Lambert Company 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents
US5192753A (en) * 1991-04-23 1993-03-09 Mcgeer Patrick L Anti-rheumatoid arthritic drugs in the treatment of dementia
CZ181493A3 (en) * 1992-09-10 1994-03-16 Lilly Co Eli The use of rhodanine derivative for the preparation of a pharmaceutical composition reducing level of sugar in blood and for treating alzheimer's disease
HUP9702293A3 (en) * 1995-01-23 2000-08-28 Lilly Co Eli 4-thiazolidinone, rhodanine and 1,3-oxathiolan-5-one derivatives for the preparation of pharmaceutical compositions suitable for the treatment of multiple sclerosis
US6136839A (en) * 1995-06-12 2000-10-24 G. D. Searle & Co. Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitor and a 5-lipoxygenase inhibitor

Also Published As

Publication number Publication date
US5912259A (en) 1999-06-15
BR9710467A (pt) 1999-08-17
PL331049A1 (en) 1999-06-21
DK0914122T3 (da) 2003-12-22
NZ332763A (en) 2000-07-28
ZA976142B (en) 1998-02-02
ATE250416T1 (de) 2003-10-15
NO990076L (no) 1999-01-08
KR20000023683A (ko) 2000-04-25
WO1998002160A1 (en) 1998-01-22
HK1020533A1 (en) 2000-05-12
CO4940509A1 (es) 2000-07-24
EP0914122B1 (en) 2003-09-24
IL127487A0 (en) 1999-10-28
EP0914122A1 (en) 1999-05-12
DE69725147D1 (de) 2003-10-30
JP2001508028A (ja) 2001-06-19
NO990076D0 (no) 1999-01-08
CN1223582A (zh) 1999-07-21
AU3649197A (en) 1998-02-09
AU726664B2 (en) 2000-11-16
DE69725147T2 (de) 2004-07-22
TR199900040T2 (xx) 1999-04-21
CN1145481C (zh) 2004-04-14
PT914122E (pt) 2003-12-31
CA2255073A1 (en) 1998-01-22
HRP970362A2 (en) 1998-04-30
ES2205247T3 (es) 2004-05-01

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees