IL125926A - Compounds related to the amidinium family, pharmaceutical preparations containing them and their uses - Google Patents

Compounds related to the amidinium family, pharmaceutical preparations containing them and their uses

Info

Publication number
IL125926A
IL125926A IL12592697A IL12592697A IL125926A IL 125926 A IL125926 A IL 125926A IL 12592697 A IL12592697 A IL 12592697A IL 12592697 A IL12592697 A IL 12592697A IL 125926 A IL125926 A IL 125926A
Authority
IL
Israel
Prior art keywords
nucleic acid
pharmaceutical composition
composition according
cells
compound
Prior art date
Application number
IL12592697A
Other languages
English (en)
Hebrew (he)
Other versions
IL125926A0 (en
Original Assignee
Centre Nat Rech Scient
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26232562&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL125926(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR9602604A external-priority patent/FR2745569B1/fr
Priority claimed from FR9609557A external-priority patent/FR2751972B1/fr
Application filed by Centre Nat Rech Scient filed Critical Centre Nat Rech Scient
Publication of IL125926A0 publication Critical patent/IL125926A0/xx
Publication of IL125926A publication Critical patent/IL125926A/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07JSTEROIDS
    • C07J41/00Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0055Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 the 17-beta position being substituted by an uninterrupted chain of at least three carbon atoms which may or may not be branched, e.g. cholane or cholestane derivatives, optionally cyclised, e.g. 17-beta-phenyl or 17-beta-furyl derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/88Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation using microencapsulation, e.g. using amphiphile liposome vesicle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/127Liposomes
    • A61K9/1271Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
IL12592697A 1996-03-01 1997-02-28 Compounds related to the amidinium family, pharmaceutical preparations containing them and their uses IL125926A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9602604A FR2745569B1 (fr) 1996-03-01 1996-03-01 Composes apparentes a la famille des amidiniums, compositions pharmaceutiques les contenant et leurs applications
FR9609557A FR2751972B1 (fr) 1996-07-30 1996-07-30 Composes apparentes a la famille des amidiniums, compositions pharmaceutiques les contenant et leurs applications
PCT/FR1997/000364 WO1997031935A1 (fr) 1996-03-01 1997-02-28 Composes apparentes a la famille des amidiniums, compositions pharmaceutiques les contenant et leurs applications

Publications (2)

Publication Number Publication Date
IL125926A0 IL125926A0 (en) 1999-04-11
IL125926A true IL125926A (en) 2004-09-27

Family

ID=26232562

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12592697A IL125926A (en) 1996-03-01 1997-02-28 Compounds related to the amidinium family, pharmaceutical preparations containing them and their uses

Country Status (18)

Country Link
US (2) US6143729A (hu)
EP (1) EP0888379B1 (hu)
JP (1) JP4271260B2 (hu)
KR (1) KR19990087372A (hu)
AT (1) ATE198599T1 (hu)
AU (1) AU723998B2 (hu)
BR (1) BRPI9707889B8 (hu)
CZ (1) CZ295225B6 (hu)
DE (1) DE69703878T2 (hu)
DK (1) DK0888379T3 (hu)
ES (1) ES2154453T3 (hu)
GR (1) GR3035205T3 (hu)
HU (1) HU228072B1 (hu)
IL (1) IL125926A (hu)
NO (1) NO311806B1 (hu)
PT (1) PT888379E (hu)
SK (1) SK283575B6 (hu)
WO (1) WO1997031935A1 (hu)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6884430B1 (en) * 1997-02-10 2005-04-26 Aventis Pharma S.A. Formulation of stabilized cationic transfection agent(s) /nucleic acid particles
FR2763943B1 (fr) * 1997-05-28 1999-07-09 Rhone Poulenc Rorer Sa Composes, leur preparation et leur utilisation pour le transfert d'acides nucleiques dans les cellules
JP2002513543A (ja) * 1998-04-02 2002-05-14 アバンテイス・フアルマ・エス・アー 新規核酸移入剤とそれらを含む組成物及びそれらの使用
FR2777017B1 (fr) * 1998-04-02 2002-08-23 Rhone Poulenc Rorer Sa Nouveaux agents de transfert d'acides nucleiques, compositions les contenant et leurs applications
DE10109898A1 (de) 2001-02-21 2002-09-05 Novosom Gmbh Lipide mit veränderlicher Ladung
JP4276439B2 (ja) * 2001-05-14 2009-06-10 サントリオン ポリチオ尿素の脂質誘導体
FR2824557B1 (fr) * 2001-05-14 2003-08-29 Aventis Pharma Sa Derives lipidiques de polythiouree
FR2829136B1 (fr) 2001-08-29 2006-11-17 Aventis Pharma Sa Derives lipidiques d'aminoglycosides
PT1479985T (pt) 2002-01-17 2017-08-03 Alfa Laval Corp Ab Evaporador submerso compreendendo um permutador de calor de placas e um compartimento cilíndrico onde está disposto o permutador de calor de placas
WO2006118283A1 (ja) * 2005-04-28 2006-11-09 Nippon Soda Co., Ltd. 新規なグアニジン化合物、製造方法及びそれらを含有する殺菌性組成物
WO2008040792A2 (en) * 2006-10-04 2008-04-10 Centre National De La Recherche Scientifique (Cnrs) Compositions comprising a sirna and lipidic 4,5-disubstituted 2-deoxystreptamine ring aminoglycoside derivatives and uses thereof
TW201019969A (en) * 2008-11-17 2010-06-01 Enzon Pharmaceuticals Inc Branched cationic lipids for nucleic acids delivery system

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5283185A (en) * 1991-08-28 1994-02-01 University Of Tennessee Research Corporation Method for delivering nucleic acids into cells
WO1995014381A1 (en) * 1993-11-24 1995-06-01 Megabios Corporation Amphiphilic derivatives of guanidine
US5777153A (en) * 1994-07-08 1998-07-07 Gilead Sciences, Inc. Cationic lipids
US6071890A (en) * 1994-12-09 2000-06-06 Genzyme Corporation Organ-specific targeting of cationic amphiphile/DNA complexes for gene therapy
US5811406A (en) * 1995-06-07 1998-09-22 Regents Of The University Of California Dry powder formulations of polynucleotide complexes

Also Published As

Publication number Publication date
JP4271260B2 (ja) 2009-06-03
NO311806B1 (no) 2002-01-28
EP0888379B1 (fr) 2001-01-10
HU228072B1 (en) 2012-09-28
PT888379E (pt) 2001-05-31
DE69703878T2 (de) 2001-04-26
AU723998B2 (en) 2000-09-07
EP0888379A1 (fr) 1999-01-07
KR19990087372A (ko) 1999-12-27
HUP9902465A1 (hu) 1999-12-28
NO983691L (no) 1998-08-12
ATE198599T1 (de) 2001-01-15
WO1997031935A1 (fr) 1997-09-04
JP2000506136A (ja) 2000-05-23
HUP9902465A3 (en) 2009-10-28
DK0888379T3 (da) 2001-01-29
SK283575B6 (sk) 2003-09-11
IL125926A0 (en) 1999-04-11
US6143729A (en) 2000-11-07
KR100452062B1 (hu) 2005-04-08
NO983691D0 (no) 1998-08-12
BR9707889A (pt) 2000-01-04
SK118298A3 (en) 1999-02-11
BR9707889B1 (pt) 2010-03-23
US6316422B1 (en) 2001-11-13
ES2154453T3 (es) 2001-04-01
CZ277298A3 (cs) 1998-12-16
AU1930497A (en) 1997-09-16
GR3035205T3 (en) 2001-04-30
CZ295225B6 (cs) 2005-06-15
DE69703878D1 (de) 2001-02-15
BRPI9707889B8 (pt) 2016-11-08

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Legal Events

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KB Patent renewed
KB Patent renewed
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