IL123635A - Substituted pyrazolyl benzenesulfonamides for use in veterinary therapies - Google Patents

Substituted pyrazolyl benzenesulfonamides for use in veterinary therapies

Info

Publication number
IL123635A
IL123635A IL12363596A IL12363596A IL123635A IL 123635 A IL123635 A IL 123635A IL 12363596 A IL12363596 A IL 12363596A IL 12363596 A IL12363596 A IL 12363596A IL 123635 A IL123635 A IL 123635A
Authority
IL
Israel
Prior art keywords
substituted pyrazolyl
pyrazolyl benzenesulfonamides
veterinary therapies
veterinary
therapies
Prior art date
Application number
IL12363596A
Other languages
English (en)
Other versions
IL123635A0 (en
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24138015&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL123635(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Searle & Co filed Critical Searle & Co
Publication of IL123635A0 publication Critical patent/IL123635A0/xx
Publication of IL123635A publication Critical patent/IL123635A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
IL12363596A 1995-09-29 1996-09-27 Substituted pyrazolyl benzenesulfonamides for use in veterinary therapies IL123635A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/536,318 US5756529A (en) 1995-09-29 1995-09-29 Substituted pyrazolyl benzenesulfonamides for use in veterinary therapies
PCT/US1996/015538 WO1997011704A1 (en) 1995-09-29 1996-09-27 Substituted pyrazolyl benzenesulfonamides for use in veterinary therapies as antiinflammatory agents

Publications (2)

Publication Number Publication Date
IL123635A0 IL123635A0 (en) 1998-10-30
IL123635A true IL123635A (en) 2003-06-24

Family

ID=24138015

Family Applications (1)

Application Number Title Priority Date Filing Date
IL12363596A IL123635A (en) 1995-09-29 1996-09-27 Substituted pyrazolyl benzenesulfonamides for use in veterinary therapies

Country Status (21)

Country Link
US (1) US5756529A (cs)
EP (1) EP0854723B1 (cs)
JP (1) JPH11514991A (cs)
KR (1) KR100498730B1 (cs)
CN (1) CN1202828A (cs)
AT (1) ATE238058T1 (cs)
AU (1) AU718300B2 (cs)
BR (1) BR9610974A (cs)
CA (1) CA2233620C (cs)
CZ (1) CZ297183B6 (cs)
DE (1) DE69627683T2 (cs)
DK (1) DK0854723T3 (cs)
ES (1) ES2197954T3 (cs)
IL (1) IL123635A (cs)
NO (1) NO321157B1 (cs)
NZ (1) NZ320919A (cs)
PL (1) PL191934B1 (cs)
PT (1) PT854723E (cs)
RO (1) RO120408B1 (cs)
RU (1) RU2253456C2 (cs)
WO (1) WO1997011704A1 (cs)

Families Citing this family (69)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6492411B1 (en) * 1993-11-30 2002-12-10 G. D. Searle & Co. Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation
AU5886296A (en) * 1995-06-02 1996-12-18 G.D. Searle & Co. Heterocyclo substituted hydroxamic acid derivatives as cyclo oxygenase-2 and 5-lipoxygenase inhibitors
US6979686B1 (en) 2001-12-07 2005-12-27 Pharmacia Corporation Substituted pyrazoles as p38 kinase inhibitors
US6087381A (en) * 1997-05-22 2000-07-11 G. D. Searle & Company Pyrazole derivatives as p38 kinase inhibitors
US6514977B1 (en) 1997-05-22 2003-02-04 G.D. Searle & Company Substituted pyrazoles as p38 kinase inhibitors
TNSN99111A1 (fr) * 1998-06-11 2005-11-10 Pfizer Derives de sulfonylbenzene nouveaux, procede pour leur preparation et compositions pharmaceutiques les contenant.
US6294558B1 (en) 1999-05-31 2001-09-25 Pfizer Inc. Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
US6727238B2 (en) * 1998-06-11 2004-04-27 Pfizer Inc. Sulfonylbenzene compounds as anti-inflammatory/analgesic agents
SA99191255B1 (ar) * 1998-11-30 2006-11-25 جي دي سيرل اند كو مركبات سيليكوكسيب celecoxib
JP2002538189A (ja) * 1999-03-10 2002-11-12 ジー．ディー．サール アンド カンパニー シクロオキシゲナーゼ−２インヒビターの投与方法と組成物
US6376519B1 (en) 1999-06-16 2002-04-23 Temple University-Of The Commonwealth Of Higher Education 1-(4-sulfamylaryl)-3-substituted-5-aryl-2-pyrazolines and inhibitors of cyclooxygenase-2
CA2392931A1 (en) 1999-12-03 2001-06-07 Pfizer Products Inc. Heterocyclo-alkylsulfonyl pyrazole derivatives as anti-inflammatory/analgesic agents
EP1104758B1 (en) * 1999-12-03 2003-07-23 Pfizer Products Inc. Acetylene derivatives as anti-inflammatory/analgesic agents
DK1104759T3 (da) * 1999-12-03 2004-01-26 Pfizer Prod Inc Heteroarylphenylpyrazolforbindelser som antiinflammatoriske/analgetiske midler
ATE234299T1 (de) * 1999-12-03 2003-03-15 Pfizer Prod Inc Sulfamoylheteroarylpyrazolverbindungen zur verwendung als analgetisches/entzündungshemmendes mittel
ES2236007T3 (es) * 1999-12-08 2005-07-16 Pharmacia Corporation Composiciones de inhibidor de ciclooxigenasa-2 ue tiene un efecto terapeutico rapido.
YU57801A (sh) * 1999-12-08 2005-07-19 Pharmacia Corporation Polimorfni kristalni oblici celecoxib-a
MY127898A (en) * 1999-12-22 2006-12-29 Pharmacia Corp Dual-release compositions of a cyclooxygenase-2 inhibitor
EP1274424A4 (en) * 2000-04-12 2003-09-17 Smithkline Beecham Corp CONNECTIONS AND PROCEDURE
US20020107250A1 (en) * 2000-04-18 2002-08-08 Madhusudan Hariharan Rapid-onset formulation of a selective cyclooxygenase-2 inhibitor
WO2001081333A2 (en) * 2000-04-25 2001-11-01 Pharmacia Corporation Regioselective synthesis of 3,4-di(carbocyclyl or heterocyclyl)thiophenes
PE20020146A1 (es) * 2000-07-13 2002-03-31 Upjohn Co Formulacion oftalmica que comprende un inhibidor de ciclooxigenasa-2 (cox-2)
US20030219461A1 (en) * 2000-09-12 2003-11-27 Britten Nancy J. Parenteral combination therapy for infective conditions
US7115565B2 (en) * 2001-01-18 2006-10-03 Pharmacia & Upjohn Company Chemotherapeutic microemulsion compositions of paclitaxel with improved oral bioavailability
US7695736B2 (en) 2001-04-03 2010-04-13 Pfizer Inc. Reconstitutable parenteral composition
US6673818B2 (en) 2001-04-20 2004-01-06 Pharmacia Corporation Fluoro-substituted benzenesulfonyl compounds for the treatment of inflammation
ATE298749T1 (de) 2001-07-05 2005-07-15 Pfizer Prod Inc Heterocyclo-alkylsulfonyl pyrazole als entzündungshemmende/analgetische mittel
US7076539B2 (en) * 2001-07-30 2006-07-11 Hewlett-Packard Development Company, L.P. Network connectivity establishment at user log-in
UA80682C2 (en) * 2001-08-06 2007-10-25 Pharmacia Corp Orally deliverable stabilized oral suspension formulation and process for the incresaing physical stability of thixotropic pharmaceutical composition
EP1444207A2 (en) 2001-09-19 2004-08-11 Pharmacia Corporation Substituted pyrazolyl-compounds for the treatment of inflammation
CA2460939C (en) 2001-09-19 2008-07-29 Pharmacia Corporation Substituted pyrazolyl compounds for the treatment of inflammation
GT200200183A (es) 2001-09-28 2003-05-23 Procedimiento para preparar derivados de heterocicloalquilsulfonil pirazol
WO2003037351A1 (en) 2001-11-02 2003-05-08 Pfizer Products Inc. Heterocyclo-alkylsulfonyl pyrazoles and their use as cox-2 inhibitors
WO2003037330A1 (en) 2001-11-02 2003-05-08 Pfizer Products Inc. Sulfonyl-and sulfonylheteroaryl-pyrazoles with a hydrazinyl or nitrogen oxide substituent at the 5-position for use as cyclooxygenase inhibitors
WO2003037335A1 (en) * 2001-11-02 2003-05-08 Pfizer Products Inc. 5-heteroatom-substituted pyrazoles
JP2005515171A (ja) 2001-11-02 2005-05-26 ファイザー・プロダクツ・インク ５−ヘテロ原子含有ピラゾールの効率的な合成法
JP2005528384A (ja) * 2002-04-08 2005-09-22 ザ オハイオ ステート ユニバーシティー リサーチ ファウンデーション 増殖性細胞においてアポトーシスを誘導するための化合物および方法
JP2005535642A (ja) 2002-06-28 2005-11-24 ニトロメッド インコーポレーティッド オキシムおよび／またはヒドラゾンを含有するニトロソ化および／またはニトロシル化シクロオキシゲナーゼ−２選択的阻害剤、組成物、および使用方法
UA79804C2 (en) 2002-07-03 2007-07-25 Janssen Pharmaceutica Nv Cck-1 receptor modulators
US20080003258A1 (en) * 2002-10-16 2008-01-03 Marcum Frank D Composition and Method for Treating Rheumatoid Arthritis
US7803787B2 (en) * 2002-10-16 2010-09-28 Arthrodynamic Technologies, Animal Health Division, Inc. Composition and method for treating connective tissue damage by transmucosal administration
US8455458B2 (en) 2002-10-16 2013-06-04 Arthrodynamic Technologies, Animal Health Division, Inc. Composition and method for treating connective tissue damage
US20080153894A1 (en) * 2002-12-19 2008-06-26 Pharmacia Corporation Cyclooxygenase-2 inhibitor and antibacterial agent combination for intramammary treatment of mastitis
PL1608407T3 (pl) * 2003-03-20 2006-12-29 Pharmacia Corp Dyspergowana kompozycja środka przeciw-zapalnego
US20050009931A1 (en) * 2003-03-20 2005-01-13 Britten Nancy Jean Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
US20050004098A1 (en) * 2003-03-20 2005-01-06 Britten Nancy Jean Dispersible formulation of an anti-inflammatory agent
US20040214753A1 (en) * 2003-03-20 2004-10-28 Britten Nancy Jean Dispersible pharmaceutical composition for treatment of mastitis and otic disorders
PL1534305T3 (pl) 2003-05-07 2007-03-30 Osteologix As Leczenie zaburzeń chrząstek i kości solami strontu rozpuszczalnymi w wodzie
US20050131028A1 (en) * 2003-09-11 2005-06-16 Pharmacia Corporation Methods and compositions for the extended duration treatment of pain, inflammation and inflammation-related disorders
US7659426B2 (en) * 2003-12-01 2010-02-09 Reverse Proteomics Research Institute Co., Ltd. Target protein of anticancer agent and novel anticancer agent (spnal) corresponding thereto
US7250434B2 (en) 2003-12-22 2007-07-31 Janssen Pharmaceutica N.V. CCK-1 receptor modulators
ITMI20041032A1 (it) * 2004-05-24 2004-08-24 Neuroscienze S C A R L Compositi farmaceutici
US7923465B2 (en) 2005-06-02 2011-04-12 Glenmark Pharmaceuticals S.A. Cannabinoid receptor ligands, pharmaceutical compositions containing them, and process for their preparation
US8128460B2 (en) * 2006-09-14 2012-03-06 The Material Works, Ltd. Method of producing rust inhibitive sheet metal through scale removal with a slurry blasting descaling cell
RU2429853C2 (ru) * 2007-02-01 2011-09-27 Дзе Иамс Компани Способ уменьшения воспаления и окислительного стресса у млекопитающих
TW200911240A (en) * 2007-06-11 2009-03-16 Kyowa Hakko Kogyo Kk Anti-tumor agent
US9186375B2 (en) 2007-06-21 2015-11-17 Arthrodynamic Technologies, Animal Health Division, Inc. Glycosaminoglycan compositions in combination with stem cells
RU2406505C2 (ru) * 2007-06-29 2010-12-20 Федеральное государственное образовательное учреждение высшего профессионального образования "САНКТ-ПЕТЕРБУРГСКАЯ ГОСУДАРСТВЕННАЯ АКАДЕМИЯ ВЕТЕРИНАРНОЙ МЕДИЦИНЫ" (ФГОУ ВПО СПГАВМ) Способ лечения воспалительного заболевания пясти и плюсны у собак
AU2011238616B2 (en) 2010-03-30 2016-08-04 Verseon Corporation Multisubstituted aromatic compounds as inhibitors of thrombin
BR112013019893A2 (pt) * 2011-02-03 2016-10-11 Lupin Ltd derivados de pirrol usados como moduladores de alfa7 nachr
CN103242233B (zh) * 2012-02-08 2014-07-30 北京博爱汇康医药科技有限责任公司 制备塞来昔布的新方法
US8859781B2 (en) * 2012-07-12 2014-10-14 Euclises Pharmaceuticals, Inc. No-releasing nonoate(nitrogen-bound)sulfonamide-linked-coxib anti-cancer agents
CN110423221A (zh) 2013-03-15 2019-11-08 维颂公司 作为凝血酶抑制剂的卤代吡唑
US9533970B2 (en) 2013-03-15 2017-01-03 Verseon Corporation Multisubstituted aromatic compounds as serine protease inhibitors
EP2886104A1 (en) 2013-12-11 2015-06-24 Patir, Suleyman An intra-articular gel
BR112017004704A2 (pt) 2014-09-17 2018-01-23 Verseon Corp composto, composição farmacêutica, e, método para tratar uma doença ou distúrbio em um indivíduo
PT3261639T (pt) 2015-02-27 2022-11-25 Verseon Int Corporation Compostos de pirazol substituídos como inibidores de serina protéase
CN107686465B (zh) * 2017-09-02 2020-10-27 东北农业大学 地拉考昔的制备方法
CN114292235B (zh) * 2021-12-29 2023-04-14 江苏天和制药有限公司 一种地拉考昔的制备和提纯方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3940418A (en) * 1972-04-07 1976-02-24 G. D. Searle & Co. Esters and amides of 4,5-dihydrobenz[g]indazole-3-carboxylic acids and related compounds
GB8814587D0 (en) * 1988-06-20 1988-07-27 Erba Carlo Spa Condensed pyrazole 3-oxo-propanenitrile derivatives & process for their preparation
PH27357A (en) * 1989-09-22 1993-06-21 Fujisawa Pharmaceutical Co Pyrazole derivatives and pharmaceutical compositions comprising the same
FR2665898B1 (fr) * 1990-08-20 1994-03-11 Sanofi Derives d'amido-3 pyrazole, procede pour leur preparation et compositions pharmaceutiques les contenant.
US5134155A (en) * 1991-08-08 1992-07-28 Ortho Pharmaceutical Corporation Tetrahydroindazole, tetrahydrocyclopentapyrazole, and hexahydrocycloheptapyrazole compounds and their use as HMG-coA reductase inhibitors
IL104311A (en) * 1992-02-05 1997-07-13 Fujisawa Pharmaceutical Co Pyrazole derivatives, processes for the preparation thereof and pharmaceutical compositions containing the same
US5466823A (en) * 1993-11-30 1995-11-14 G.D. Searle & Co. Substituted pyrazolyl benzenesulfonamides
US5434178A (en) * 1993-11-30 1995-07-18 G.D. Searle & Co. 1,3,5 trisubstituted pyrazole compounds for treatment of inflammation
US5401765A (en) * 1993-11-30 1995-03-28 G. D. Searle 1,4,5-triphenyl pyrazolyl compounds for the treatment of inflammation and inflammation-related disorders
US5475018A (en) * 1993-11-30 1995-12-12 G. D. Searle & Co. 1,5-diphenyl pyrazole compounds for treatment of inflammation
PT731795E (pt) * 1993-11-30 2000-05-31 Searle & Co Pirazolilbenzenossulfonamidas para o tratamento de inflamacoes

Also Published As

Publication number Publication date
EP0854723B1 (en) 2003-04-23
CA2233620A1 (en) 1997-04-03
IL123635A0 (en) 1998-10-30
AU7376896A (en) 1997-04-17
CZ297183B6 (cs) 2006-09-13
KR100498730B1 (ko) 2005-09-09
PT854723E (pt) 2003-08-29
PL191934B1 (pl) 2006-07-31
NO981392D0 (no) 1998-03-27
NZ320919A (en) 1999-10-28
AU718300B2 (en) 2000-04-13
DE69627683D1 (de) 2003-05-28
WO1997011704A1 (en) 1997-04-03
BR9610974A (pt) 1999-07-13
CZ89798A3 (cs) 1999-04-14
US5756529A (en) 1998-05-26
DE69627683T2 (de) 2003-12-18
CA2233620C (en) 2011-11-22
PL325952A1 (en) 1998-08-17
EP0854723A1 (en) 1998-07-29
CN1202828A (zh) 1998-12-23
DK0854723T3 (da) 2003-08-11
NO321157B1 (no) 2006-03-27
RU2253456C2 (ru) 2005-06-10
KR19990063874A (ko) 1999-07-26
RO120408B1 (ro) 2006-01-30
ATE238058T1 (de) 2003-05-15
ES2197954T3 (es) 2004-01-16
JPH11514991A (ja) 1999-12-21
NO981392L (no) 1998-05-25

Similar Documents

Publication Publication Date Title
IL123635A (en) Substituted pyrazolyl benzenesulfonamides for use in veterinary therapies
IL123131A0 (en) Use of indigestible oligosaccharides to prevent and treat diarrhea
EP0517512A3 (en) Computer system and method of establishing communication therein
IL94490A0 (en) Stable,cosmetically acceptable topical gel formulation and method of treatment for acne
GB8912654D0 (en) Method and system for preventing unauthorized use of software
HU9601455D0 (en) Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation
ZA979551B (en) System and method for delivery of neutron beams for medical therapy.
ZA949418B (en) Substituted pyrazolyl benzenesulfonamides for the treatment of inflammation
ZA931869B (en) Treatment of fibrotic disorders
AU6226894A (en) Implantable therapy systems and methods
AU2644888A (en) Method of healing wounds in horses
NO950925L (no) Preparat og fremgangsmåte for behandling av hårtap
SG50419A1 (en) Methods of therapeutic and anaesthetic treatment and preparations therefor
AU7210491A (en) Method and device for continuously treating of fuel
CS182489A2 (en) Means for fighting against vermin and method of active substances production
AU3733293A (en) Method and agents for promoting wound healing
AU3539189A (en) Prophylactic and therapeutic methods for treating edema with phallotoxins
PL311659A1 (en) Method of treating animal bowels
MX9803681A (es) Inhibicion de la expresion de membrana.
PL325557A1 (en) Agent for use in prophylactics and/or treatmet of human and animal hair loss
AU3286893A (en) Therapeutic device and method of treatment
AU5769390A (en) Process and installation of treatment of an animal skin
AU1962788A (en) Reproductive hormone-specific immunocontraceptives and methods of using them
NZ331846A (en) Method for preparing a medicament using olanzapine for treating insomnia
UA19610A (uk) Спосіб лікуваhhя опісторхозhої іhвазії

Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXP Patent expired