IL122942A0 - Esters of 1-beta-d-arabinofuranosylcytosine and pharmaceutical compositions containing them - Google Patents

Esters of 1-beta-d-arabinofuranosylcytosine and pharmaceutical compositions containing them

Info

Publication number
IL122942A0
IL122942A0 IL12294296A IL12294296A IL122942A0 IL 122942 A0 IL122942 A0 IL 122942A0 IL 12294296 A IL12294296 A IL 12294296A IL 12294296 A IL12294296 A IL 12294296A IL 122942 A0 IL122942 A0 IL 122942A0
Authority
IL
Israel
Prior art keywords
pharmaceutical compositions
arabinofuranosylcytosine
beta
esters
compositions containing
Prior art date
Application number
IL12294296A
Other languages
English (en)
Original Assignee
Norsk Hydro As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Norsk Hydro As filed Critical Norsk Hydro As
Publication of IL122942A0 publication Critical patent/IL122942A0/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06Pyrimidine radicals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/052Imidazole radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/056Triazole or tetrazole radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16Purine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)
  • Artificial Filaments (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polyamides (AREA)
IL12294296A 1995-07-25 1996-07-12 Esters of 1-beta-d-arabinofuranosylcytosine and pharmaceutical compositions containing them IL122942A0 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9515279.9A GB9515279D0 (en) 1995-07-25 1995-07-25 Improved therapeutic agents
PCT/NO1996/000179 WO1997005154A1 (en) 1995-07-25 1996-07-12 Improved therapeutic agents

Publications (1)

Publication Number Publication Date
IL122942A0 true IL122942A0 (en) 1999-05-09

Family

ID=10778247

Family Applications (2)

Application Number Title Priority Date Filing Date
IL12294296A IL122942A0 (en) 1995-07-25 1996-07-12 Esters of 1-beta-d-arabinofuranosylcytosine and pharmaceutical compositions containing them
IL122942A IL122942A (en) 1995-07-25 1998-01-15 Pharmaceutical preparations containing esters of D – ß – 1 - arabinopuranosyl cytosine and some new esters of this type

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL122942A IL122942A (en) 1995-07-25 1998-01-15 Pharmaceutical preparations containing esters of D – ß – 1 - arabinopuranosyl cytosine and some new esters of this type

Country Status (25)

Country Link
US (2) US6316425B1 (pt)
EP (1) EP0842185B1 (pt)
JP (2) JP4372227B2 (pt)
KR (1) KR100401909B1 (pt)
AT (1) ATE207076T1 (pt)
AU (1) AU714814B2 (pt)
CA (1) CA2227533C (pt)
CZ (1) CZ291612B6 (pt)
DE (1) DE69616074T2 (pt)
DK (1) DK0842185T3 (pt)
ES (1) ES2166900T3 (pt)
GB (1) GB9515279D0 (pt)
HU (1) HU224839B1 (pt)
IL (2) IL122942A0 (pt)
MX (1) MX9800622A (pt)
NO (1) NO313985B1 (pt)
NZ (1) NZ313790A (pt)
PL (1) PL183601B1 (pt)
PT (1) PT842185E (pt)
RU (1) RU2165260C2 (pt)
SK (1) SK283003B6 (pt)
TW (1) TW434251B (pt)
UA (1) UA55389C2 (pt)
WO (1) WO1997005154A1 (pt)
ZA (1) ZA966047B (pt)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6458772B1 (en) 1909-10-07 2002-10-01 Medivir Ab Prodrugs
CA2271135A1 (en) * 1996-11-12 1998-05-22 Medivir Ab Nucleosides
NZ336676A (en) * 1997-01-24 2000-01-28 Norsk Hydro As Gemcitabine esters or amides useful as anti-cancer and anti-viral agents
US7393862B2 (en) * 2002-05-17 2008-07-01 Celgene Corporation Method using 3-(4-amino-1-oxo-1,3-dihydro-isoindol-2-yl)-piperidine-2,6-dione for treatment of certain leukemias
JP2007509994A (ja) * 2003-11-03 2007-04-19 コグニス・アイピー・マネージメント・ゲゼルシャフト・ミット・ベシュレンクテル・ハフツング アシルリボヌクレオシドおよびアシルデオキシリボヌクレオシド
NO324263B1 (no) * 2005-12-08 2007-09-17 Clavis Pharma Asa Kjemiske forbindelser, anvendelse derav ved behandling av kreft, samt farmasoytiske preparater som omfatter slike forbindelser
US8497292B2 (en) * 2005-12-28 2013-07-30 Translational Therapeutics, Inc. Translational dysfunction based therapeutics
EP2205073A4 (en) * 2007-09-26 2013-03-06 Sinai School Medicine AZACYTIDINE ANALOGS AND USES THEREOF
GB0808357D0 (en) * 2008-05-08 2008-06-18 Cyclacel Ltd Process
MX2012005677A (es) * 2009-11-20 2012-08-23 Clavis Pharma Asa Formulaciones parentales de derivados de gemcitabina.
US8912162B2 (en) 2010-07-13 2014-12-16 Clavis Pharma Asa Parenteral formulations of elacytarabine derivatives
DK2832740T3 (da) * 2012-03-28 2019-07-15 Fujifilm Corp SALT AF 1-(2-DEOXY-2-FLUOR-4-THIO-beta-D-ARABINOFURANOSYL)CYTOSIN
US20210052619A1 (en) 2018-01-15 2021-02-25 Yinuoke Medicine Science And Technology Company Ltd. Treatments for cachexia

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3894000A (en) * 1971-01-27 1975-07-08 Upjohn Co Ara-cytidine derivatives and process of preparation
CA2079413C (en) 1991-09-30 2003-09-09 Masakatsu Kaneko Pyrimidine nucleoside derivatives having anti-tumor activity, their preparation and use
GB9307043D0 (en) 1993-04-05 1993-05-26 Norsk Hydro As Chemical compounds
US5641758A (en) 1993-11-10 1997-06-24 Kluge; Michael Cytarabine derivatives, the preparation and use thereof

Also Published As

Publication number Publication date
AU714814B2 (en) 2000-01-13
DK0842185T3 (da) 2002-02-04
PL183601B1 (pl) 2002-06-28
HU224839B1 (en) 2006-03-28
US6316425B1 (en) 2001-11-13
CA2227533A1 (en) 1997-02-13
CZ291612B6 (cs) 2003-04-16
ES2166900T3 (es) 2002-05-01
ATE207076T1 (de) 2001-11-15
GB9515279D0 (en) 1995-09-20
HUP9900924A3 (en) 2001-06-28
NO980296L (no) 1998-01-23
SK8098A3 (en) 1998-07-08
KR19990035804A (ko) 1999-05-25
EP0842185A1 (en) 1998-05-20
NZ313790A (en) 1999-07-29
IL122942A (en) 2006-12-10
WO1997005154A1 (en) 1997-02-13
JP2009215326A (ja) 2009-09-24
DE69616074D1 (de) 2001-11-22
TW434251B (en) 2001-05-16
RU2165260C2 (ru) 2001-04-20
SK283003B6 (sk) 2003-01-09
CA2227533C (en) 2007-01-09
MX9800622A (es) 1998-11-30
EP0842185B1 (en) 2001-10-17
PT842185E (pt) 2002-04-29
JP2002504068A (ja) 2002-02-05
CZ16398A3 (cs) 1998-06-17
KR100401909B1 (ko) 2004-02-14
NO313985B1 (no) 2003-01-13
AU6633596A (en) 1997-02-26
US6335322B1 (en) 2002-01-01
DE69616074T2 (de) 2002-06-06
JP5087052B2 (ja) 2012-11-28
JP4372227B2 (ja) 2009-11-25
NO980296D0 (no) 1998-01-23
UA55389C2 (uk) 2003-04-15
ZA966047B (en) 1997-02-04
PL324690A1 (en) 1998-06-08
HUP9900924A2 (hu) 2001-05-28

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Legal Events

Date Code Title Description
KB Patent renewed
ERR Corrigendum

Free format text: IN JOURNAL 9/2006 P. 3455 PATENT APPLICATION NO. 122942 GB 25.7.1995 WO 1997/05154 CORRECT PRIORITYCLAIM CORRECT INTERNATIONAL PUBLICATION NO. TO JULY 24, 2007

FF Patent granted
KB Patent renewed