IL121860A0 - Interleukin-18 binding proteins their preparation and use - Google Patents

Interleukin-18 binding proteins their preparation and use

Info

Publication number
IL121860A0
IL121860A0 IL12186097A IL12186097A IL121860A0 IL 121860 A0 IL121860 A0 IL 121860A0 IL 12186097 A IL12186097 A IL 12186097A IL 12186097 A IL12186097 A IL 12186097A IL 121860 A0 IL121860 A0 IL 121860A0
Authority
IL
Israel
Prior art keywords
interleukin
preparation
binding proteins
proteins
binding
Prior art date
Application number
IL12186097A
Other languages
English (en)
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IL12155497A external-priority patent/IL121554A0/xx
Priority claimed from IL12163997A external-priority patent/IL121639A0/xx
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Priority to IL12186097A priority Critical patent/IL121860A0/xx
Priority to IL12213497A priority patent/IL122134A0/xx
Publication of IL121860A0 publication Critical patent/IL121860A0/xx
Priority to IL12546398A priority patent/IL125463A0/xx
Priority to EA200000216A priority patent/EA003675B1/ru
Priority to JP2000509740A priority patent/JP4272348B2/ja
Priority to HK00108180.3A priority patent/HK1028773B/xx
Priority to US09/485,632 priority patent/US6605280B1/en
Priority to SK176-2000A priority patent/SK287194B6/sk
Priority to SI9830922T priority patent/SI1003781T1/sl
Priority to EP98938877A priority patent/EP1003781B1/en
Priority to NZ502392A priority patent/NZ502392A/xx
Priority to AT98938877T priority patent/ATE443719T1/de
Priority to CA2298855A priority patent/CA2298855C/en
Priority to DE1003781T priority patent/DE1003781T1/de
Priority to AU87460/98A priority patent/AU755794B2/en
Priority to CZ20000490A priority patent/CZ300818B6/cs
Priority to ES98938877T priority patent/ES2149149T3/es
Priority to CNB988081342A priority patent/CN1243021C/zh
Priority to EEP200000073A priority patent/EE05538B1/xx
Priority to DE69841175T priority patent/DE69841175D1/de
Priority to HU0003533A priority patent/HU226698B1/hu
Priority to DK98938877.2T priority patent/DK1003781T3/da
Priority to BRPI9811940-0 priority patent/BRPI9811940B8/pt
Priority to PT98938877T priority patent/PT1003781E/pt
Priority to UA2000031437A priority patent/UA75862C2/uk
Priority to IL13452398A priority patent/IL134523A0/xx
Priority to PL338647A priority patent/PL206070B1/pl
Priority to PCT/IL1998/000379 priority patent/WO1999009063A1/en
Priority to KR1020007001504A priority patent/KR100687388B1/ko
Priority to ARP980104054A priority patent/AR013422A1/es
Priority to BG104149A priority patent/BG65519B1/bg
Priority to NO20000700A priority patent/NO327240B1/no
Priority to IL134523A priority patent/IL134523A/en
Priority to US09/790,338 priority patent/US7220717B2/en
Priority to US10/434,583 priority patent/US7101689B2/en
Priority to US11/376,794 priority patent/US7799541B2/en
Priority to US11/505,554 priority patent/US7704944B2/en
Priority to US11/724,737 priority patent/US7696154B2/en
Priority to ARP070104104A priority patent/AR062867A2/es
Priority to US12/511,756 priority patent/US8436148B2/en
Priority to CY20091101232T priority patent/CY1109664T1/el
Priority to US12/715,089 priority patent/US20100254941A1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C07K14/7155—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons for interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/82—Proteins from microorganisms
    • Y10S530/826—Viruses
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/827—Proteins from mammals or birds
    • Y10S530/834—Urine; urinary system

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Neurology (AREA)
  • Hematology (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
IL12186097A 1997-08-14 1997-09-29 Interleukin-18 binding proteins their preparation and use IL121860A0 (en)

Priority Applications (42)

Application Number Priority Date Filing Date Title
IL12186097A IL121860A0 (en) 1997-08-14 1997-09-29 Interleukin-18 binding proteins their preparation and use
IL12213497A IL122134A0 (en) 1997-08-14 1997-11-06 Interleukin-18 binding proteins their preparation and use
IL12546398A IL125463A0 (en) 1997-08-14 1998-07-22 Interleukin-18 binding proteins their preparation and use
PL338647A PL206070B1 (pl) 1997-08-14 1998-08-13 Izolowane białko wiążące IL-18, sposób jego wytwarzania i izolowania, izolowana cząsteczka DNA, zdolny do replikacji wektor, transformowana komórka gospodarza, przeciwciało, kompozycja farmaceutyczna oraz zastosowanie
PCT/IL1998/000379 WO1999009063A1 (en) 1997-08-14 1998-08-13 Interleukin-18 binding proteins, their preparation and use
KR1020007001504A KR100687388B1 (ko) 1997-08-14 1998-08-13 인터루킨-18 결합 단백질, 이들의 제조방법 및 용도
EEP200000073A EE05538B1 (et) 1997-08-14 1998-08-13 Interleukiin-18 seostuvad valgud, nende valmistamine ja kasutamine
BRPI9811940-0 BRPI9811940B8 (pt) 1997-08-14 1998-08-13 vetor de expressão para um polipeptídeo de ligação da interleucina-18 (il-18-bp), célula hospedeira procariótica transformada com o referido vetor, processo para produção de il-18-bp, proteína de fusão compreendendo o referido polipeptídeo, bem como il-18bp modificada.
HK00108180.3A HK1028773B (en) 1997-08-14 1998-08-13 Interleukin-18 binding proteins, their preparation and use
US09/485,632 US6605280B1 (en) 1997-08-14 1998-08-13 Interleukin-18 binding proteins, their preparation and use for blocking the activity of IL-18
SK176-2000A SK287194B6 (sk) 1997-08-14 1998-08-13 Interleukínový-18 väzbový proteín - IL-18BP, DNA, replikovateľný vektor, transformovaná hostiteľská bunka, protilátka k IL-18BP, spôsob výroby IL-18BP, prostriedok s jeho obsahom a jeho použitie
SI9830922T SI1003781T1 (sl) 1997-08-14 1998-08-13 Interlevkin-18 vezavni proteini, njihova priprava in uporaba
EP98938877A EP1003781B1 (en) 1997-08-14 1998-08-13 Interleukin-18 binding proteins, their preparation and use
NZ502392A NZ502392A (en) 1997-08-14 1998-08-13 Interleukin-18 binding proteins (IL-18BP) their preparation and use in pharmaceuticals
AT98938877T ATE443719T1 (de) 1997-08-14 1998-08-13 Interleukin-18 bindende proteine, deren herstellung und verwendung
CA2298855A CA2298855C (en) 1997-08-14 1998-08-13 Interleukin-18 binding proteins, their preparation and use
DE1003781T DE1003781T1 (de) 1997-08-14 1998-08-13 Interleukin-18 bindende proteine, deren herstellung und verwendung
AU87460/98A AU755794B2 (en) 1997-08-14 1998-08-13 Interleukin-18 binding proteins, their preparation and use
CZ20000490A CZ300818B6 (cs) 1997-08-14 1998-08-13 Interleukin-18-vazebné proteiny, príprava a použití
ES98938877T ES2149149T3 (es) 1997-08-14 1998-08-13 Proteinas de union a interleuquina-18, su preparacion y uso.
CNB988081342A CN1243021C (zh) 1997-08-14 1998-08-13 白细胞介素－18结合蛋白质及其制备和用途
EA200000216A EA003675B1 (ru) 1997-08-14 1998-08-13 Белки, связывающие интерлейкин-18, их получение и применение
DE69841175T DE69841175D1 (de) 1997-08-14 1998-08-13 Interleukin-18 bindende proteine, deren herstellung und verwendung
HU0003533A HU226698B1 (en) 1997-08-14 1998-08-13 Interleukin-18 binding proteins, their preparation and use
DK98938877.2T DK1003781T3 (da) 1997-08-14 1998-08-13 Interleukin-18-bindende proteiner, fremstilling og anvendelse af disse
JP2000509740A JP4272348B2 (ja) 1997-08-14 1998-08-13 インターロイキン−１８結合タンパク質、それらの調製および用途
PT98938877T PT1003781E (pt) 1997-08-14 1998-08-13 Proteínas de ligação a interleucina-18, sua preparação e utilização
UA2000031437A UA75862C2 (uk) 1997-08-14 1998-08-13 Виділений поліпептид, що зв'язується з il-18 (il-18bp) (варіанти), виділена молекула нуклеїнової кислоти, що його кодує (варіанти), антитіло, що зв'язується з даним поліпептидом, спосіб очищення il-18bp та композиція, що його містить
IL13452398A IL134523A0 (en) 1997-08-14 1998-08-13 Interleukin-18 binding proteins, their preparation and use
ARP980104054A AR013422A1 (es) 1997-08-14 1998-08-14 UN VECTOR DE EXPRESIoN REPLICABLE QUE COMPRENDE UN ÁCIDO NUCLEICO QUE CODIFICA PARA UN POLIPÉPTIDO, UNA CÉLULA HUÉSPED ANIMAL AISLADA INCAPAZ DE CONDUCIR A UN ORGANISMO COMPLETO, UN MICROORGANISMO, UN MÉTODO PARA PRODUCIR UN POLIPEPTIDO DE SEC IN N° 2, UNA PROTEíNA DE FUSIoN, UN ANTICUERPO MONOCLONA
BG104149A BG65519B1 (bg) 1997-08-14 2000-02-10 Белтъци, свързващи интерлевкин-18, тяхното получаване и приложение
NO20000700A NO327240B1 (no) 1997-08-14 2000-02-11 Interleukin-18-bindende protein, DNA som koder for dette, vektor og celle inneholdende slikt DNA, fremgangsmate for fremstilling av proteinet, antistoffer som reagerer mot proteinet samt anvendelse av proteinet for fremstilling av medikamenter.
IL134523A IL134523A (en) 1997-08-14 2000-02-13 Proteins that bind interleukin-18, their preparation and use
US09/790,338 US7220717B2 (en) 1997-08-14 2001-02-21 Interleukin-18 binding proteins, their preparation and use
US10/434,583 US7101689B2 (en) 1997-08-14 2003-05-08 Interleukin-18 binding proteins, their preparation and use
US11/376,794 US7799541B2 (en) 1997-08-14 2006-03-15 Interleukin-18 binding proteins, their preparation and use
US11/505,554 US7704944B2 (en) 1997-08-14 2006-08-16 Interleukin-18 binding proteins, their preparation and use for the treatment of sepsis
US11/724,737 US7696154B2 (en) 1997-08-14 2007-03-15 Methods for treating interleukin-18 mediated disorders with interleukin-18 binding proteins
ARP070104104A AR062867A2 (es) 1997-08-14 2007-09-17 Proteinas de enlace a interleuquina -18, (il- 18bp), secuencias de adn que codifican para la il -18 bp, secuencias de adnc, un vehiculo de expresion replicable, celula huesped, un proceso para su produccion y aislacion, anticuerpos, composiciones farmaceuticas, el uso de dichas composiciones para la
US12/511,756 US8436148B2 (en) 1997-08-14 2009-07-29 Antibodies against interleukin-18 binding protein, their preparation and use
CY20091101232T CY1109664T1 (el) 1997-08-14 2009-11-25 Πρωτεϊνες δεσμευσεως ιντερλευκινης-18, η παρασκευη και η χρηση τους
US12/715,089 US20100254941A1 (en) 1997-08-14 2010-03-01 Interleukin-18 binding proteins, their preparation and use for the treatment of sepsis

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
IL12155497A IL121554A0 (en) 1997-08-14 1997-08-14 Interleukin-18 binding proteins their preparation and use
IL12163997A IL121639A0 (en) 1997-08-14 1997-08-27 Interleukin-18 binding proteins their preparation and use
IL12186097A IL121860A0 (en) 1997-08-14 1997-09-29 Interleukin-18 binding proteins their preparation and use
IL12213497A IL122134A0 (en) 1997-08-14 1997-11-06 Interleukin-18 binding proteins their preparation and use
IL12546398A IL125463A0 (en) 1997-08-14 1998-07-22 Interleukin-18 binding proteins their preparation and use
PCT/IL1998/000379 WO1999009063A1 (en) 1997-08-14 1998-08-13 Interleukin-18 binding proteins, their preparation and use

Publications (1)

Publication Number Publication Date
IL121860A0 true IL121860A0 (en) 1998-02-22

Family

ID=27517687

Family Applications (5)

Application Number Title Priority Date Filing Date
IL12186097A IL121860A0 (en) 1997-08-14 1997-09-29 Interleukin-18 binding proteins their preparation and use
IL12213497A IL122134A0 (en) 1997-08-14 1997-11-06 Interleukin-18 binding proteins their preparation and use
IL12546398A IL125463A0 (en) 1997-08-14 1998-07-22 Interleukin-18 binding proteins their preparation and use
IL13452398A IL134523A0 (en) 1997-08-14 1998-08-13 Interleukin-18 binding proteins, their preparation and use
IL134523A IL134523A (en) 1997-08-14 2000-02-13 Proteins that bind interleukin-18, their preparation and use

Family Applications After (4)

Application Number Title Priority Date Filing Date
IL12213497A IL122134A0 (en) 1997-08-14 1997-11-06 Interleukin-18 binding proteins their preparation and use
IL12546398A IL125463A0 (en) 1997-08-14 1998-07-22 Interleukin-18 binding proteins their preparation and use
IL13452398A IL134523A0 (en) 1997-08-14 1998-08-13 Interleukin-18 binding proteins, their preparation and use
IL134523A IL134523A (en) 1997-08-14 2000-02-13 Proteins that bind interleukin-18, their preparation and use

Country Status (28)

Country Link
US (4) US6605280B1 (enEXAMPLES)
EP (1) EP1003781B1 (enEXAMPLES)
JP (1) JP4272348B2 (enEXAMPLES)
KR (1) KR100687388B1 (enEXAMPLES)
CN (1) CN1243021C (enEXAMPLES)
AR (2) AR013422A1 (enEXAMPLES)
AT (1) ATE443719T1 (enEXAMPLES)
AU (1) AU755794B2 (enEXAMPLES)
BG (1) BG65519B1 (enEXAMPLES)
BR (1) BRPI9811940B8 (enEXAMPLES)
CA (1) CA2298855C (enEXAMPLES)
CY (1) CY1109664T1 (enEXAMPLES)
CZ (1) CZ300818B6 (enEXAMPLES)
DE (2) DE69841175D1 (enEXAMPLES)
DK (1) DK1003781T3 (enEXAMPLES)
EA (1) EA003675B1 (enEXAMPLES)
EE (1) EE05538B1 (enEXAMPLES)
ES (1) ES2149149T3 (enEXAMPLES)
HU (1) HU226698B1 (enEXAMPLES)
IL (5) IL121860A0 (enEXAMPLES)
NO (1) NO327240B1 (enEXAMPLES)
NZ (1) NZ502392A (enEXAMPLES)
PL (1) PL206070B1 (enEXAMPLES)
PT (1) PT1003781E (enEXAMPLES)
SI (1) SI1003781T1 (enEXAMPLES)
SK (1) SK287194B6 (enEXAMPLES)
UA (1) UA75862C2 (enEXAMPLES)
WO (1) WO1999009063A1 (enEXAMPLES)

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JP4272348B2 (ja) 2009-06-03
UA75862C2 (uk) 2006-06-15
EP1003781A1 (en) 2000-05-31
EA200000216A1 (ru) 2000-08-28
CA2298855A1 (en) 1999-02-25
US7101689B2 (en) 2006-09-05
HU226698B1 (en) 2009-07-28
IL125463A0 (en) 1999-03-12
US20060154294A1 (en) 2006-07-13
EA003675B1 (ru) 2003-08-28
KR100687388B1 (ko) 2007-02-26
EE200000073A (enEXAMPLES) 2000-10-16
BRPI9811940A (pt) 2000-09-05
NO20000700D0 (no) 2000-02-11
HUP0003533A2 (hu) 2001-01-29
HUP0003533A3 (en) 2003-08-28
KR20010022900A (ko) 2001-03-26
SK287194B6 (sk) 2010-03-08
IL122134A0 (en) 1998-04-05
NZ502392A (en) 2002-12-20
CZ300818B6 (cs) 2009-08-19
NO327240B1 (no) 2009-05-18
US20040037829A1 (en) 2004-02-26
IL134523A0 (en) 2001-04-30
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US6605280B1 (en) 2003-08-12
HK1028773A1 (en) 2001-03-02
PL206070B1 (pl) 2010-06-30
BRPI9811940B1 (pt) 2011-10-04
AR062867A2 (es) 2008-12-10
AU8746098A (en) 1999-03-08
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US8436148B2 (en) 2013-05-07
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AU755794B2 (en) 2002-12-19
CZ2000490A3 (cs) 2000-08-16
BG104149A (bg) 2000-08-31
CN1267307A (zh) 2000-09-20
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ATE443719T1 (de) 2009-10-15
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DE1003781T1 (de) 2001-01-11
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