IL117773A - Solid lipid compositions of coenzyme Q10 for enhanced oral bioavailability - Google Patents

Solid lipid compositions of coenzyme Q10 for enhanced oral bioavailability

Info

Publication number
IL117773A
IL117773A IL11777396A IL11777396A IL117773A IL 117773 A IL117773 A IL 117773A IL 11777396 A IL11777396 A IL 11777396A IL 11777396 A IL11777396 A IL 11777396A IL 117773 A IL117773 A IL 117773A
Authority
IL
Israel
Prior art keywords
oral bioavailability
coenzyme
enhanced oral
lipid compositions
solid lipid
Prior art date
Application number
IL11777396A
Other languages
English (en)
Other versions
IL117773A0 (en
Inventor
Shimon Amselem
Original Assignee
Pharmos Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmos Ltd filed Critical Pharmos Ltd
Priority to IL11777396A priority Critical patent/IL117773A/xx
Publication of IL117773A0 publication Critical patent/IL117773A0/xx
Priority to AU24339/97A priority patent/AU722217B2/en
Priority to JP53557397A priority patent/JP4219403B2/ja
Priority to CA002251194A priority patent/CA2251194C/en
Priority to EP97920049A priority patent/EP0954284B1/en
Priority to IL12638497A priority patent/IL126384A/en
Priority to DE69733966T priority patent/DE69733966T2/de
Priority to PCT/US1997/005453 priority patent/WO1997036577A1/en
Priority to US08/833,075 priority patent/US5989583A/en
Priority to BR9708423-9A priority patent/BR9708423A/pt
Priority to ES97920049T priority patent/ES2249797T3/es
Priority to AT97920049T priority patent/ATE301454T1/de
Publication of IL117773A publication Critical patent/IL117773A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Fats And Perfumes (AREA)
IL11777396A 1996-04-02 1996-04-02 Solid lipid compositions of coenzyme Q10 for enhanced oral bioavailability IL117773A (en)

Priority Applications (12)

Application Number Priority Date Filing Date Title
IL11777396A IL117773A (en) 1996-04-02 1996-04-02 Solid lipid compositions of coenzyme Q10 for enhanced oral bioavailability
AT97920049T ATE301454T1 (de) 1996-04-02 1997-04-02 Feste lipidzusammensetzungen von lipophilen verbindungen zur verbesserten oralen bioverfügbarkeit
EP97920049A EP0954284B1 (en) 1996-04-02 1997-04-02 Solid lipid compositions of lipophilic compounds for enhanced oral bioavailability
JP53557397A JP4219403B2 (ja) 1996-04-02 1997-04-02 経口の生物学的利用率増大のための親油性化合物の固形脂質組成物
CA002251194A CA2251194C (en) 1996-04-02 1997-04-02 Solid lipid compositions of lipophilic compounds for enhanced oral bioavailability
AU24339/97A AU722217B2 (en) 1996-04-02 1997-04-02 Solid lipid compositions of lipophilic compounds for enhanced oral bioavailability
IL12638497A IL126384A (en) 1996-04-02 1997-04-02 Solid lipid compositions of lipophilic compounds for enhanced oral bioavailability
DE69733966T DE69733966T2 (de) 1996-04-02 1997-04-02 Feste lipidzusammensetzungen von lipophilen verbindungen zur verbesserten oralen bioverfügbarkeit
PCT/US1997/005453 WO1997036577A1 (en) 1996-04-02 1997-04-02 Solid lipid compositions of lipophilic compounds for enhanced oral bioavailability
US08/833,075 US5989583A (en) 1996-04-02 1997-04-02 Solid lipid compositions of lipophilic compounds for enhanced oral bioavailability
BR9708423-9A BR9708423A (pt) 1996-04-02 1997-04-02 Composição lipìdica sólida seca, e, processos para produzir a mesma e para liberar uma substância lipofìlica em um mamìfero em necessidade de tal substância.
ES97920049T ES2249797T3 (es) 1996-04-02 1997-04-02 Composiciones de lipidos solidos de componentes lipofilicos para mejorar la biodisponibilidad oral.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL11777396A IL117773A (en) 1996-04-02 1996-04-02 Solid lipid compositions of coenzyme Q10 for enhanced oral bioavailability

Publications (2)

Publication Number Publication Date
IL117773A0 IL117773A0 (en) 1996-08-04
IL117773A true IL117773A (en) 2000-10-31

Family

ID=11068733

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11777396A IL117773A (en) 1996-04-02 1996-04-02 Solid lipid compositions of coenzyme Q10 for enhanced oral bioavailability

Country Status (10)

Country Link
US (1) US5989583A (xx)
EP (1) EP0954284B1 (xx)
JP (1) JP4219403B2 (xx)
AT (1) ATE301454T1 (xx)
AU (1) AU722217B2 (xx)
BR (1) BR9708423A (xx)
DE (1) DE69733966T2 (xx)
ES (1) ES2249797T3 (xx)
IL (1) IL117773A (xx)
WO (1) WO1997036577A1 (xx)

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DE69733966D1 (de) 2005-09-15
IL117773A0 (en) 1996-08-04
JP4219403B2 (ja) 2009-02-04
BR9708423A (pt) 2000-01-04
ATE301454T1 (de) 2005-08-15
US5989583A (en) 1999-11-23
AU722217B2 (en) 2000-07-27
AU2433997A (en) 1997-10-22
EP0954284B1 (en) 2005-08-10
JP2000507594A (ja) 2000-06-20
ES2249797T3 (es) 2006-04-01
EP0954284A1 (en) 1999-11-10
EP0954284A4 (en) 2000-01-26
WO1997036577A1 (en) 1997-10-09
DE69733966T2 (de) 2006-05-18

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