IL117749A - Cyclic peptides process for their preparation and antifungal compositions containing them - Google Patents

Cyclic peptides process for their preparation and antifungal compositions containing them

Info

Publication number
IL117749A
IL117749A IL11774996A IL11774996A IL117749A IL 117749 A IL117749 A IL 117749A IL 11774996 A IL11774996 A IL 11774996A IL 11774996 A IL11774996 A IL 11774996A IL 117749 A IL117749 A IL 117749A
Authority
IL
Israel
Prior art keywords
preparation
compositions containing
cyclic peptides
antifungal compositions
peptides process
Prior art date
Application number
IL11774996A
Other languages
English (en)
Other versions
IL117749A0 (en
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of IL117749A0 publication Critical patent/IL117749A0/xx
Publication of IL117749A publication Critical patent/IL117749A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL11774996A 1995-04-07 1996-04-01 Cyclic peptides process for their preparation and antifungal compositions containing them IL117749A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US41834195A 1995-04-07 1995-04-07

Publications (2)

Publication Number Publication Date
IL117749A0 IL117749A0 (en) 1996-08-04
IL117749A true IL117749A (en) 2000-06-01

Family

ID=23657711

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11774996A IL117749A (en) 1995-04-07 1996-04-01 Cyclic peptides process for their preparation and antifungal compositions containing them

Country Status (29)

Country Link
US (1) US5646111A (zh)
EP (1) EP0736541B1 (zh)
JP (1) JPH11504005A (zh)
KR (1) KR19980703646A (zh)
CN (1) CN1185739A (zh)
AR (2) AR004170A1 (zh)
AT (1) ATE228535T1 (zh)
AU (1) AU702841B2 (zh)
BR (1) BR9604906A (zh)
CA (1) CA2217048A1 (zh)
CO (1) CO4700480A1 (zh)
CZ (1) CZ291702B6 (zh)
DE (1) DE69624966T2 (zh)
EA (1) EA000464B1 (zh)
ES (1) ES2187617T3 (zh)
HU (1) HUP9800809A3 (zh)
IL (1) IL117749A (zh)
IN (1) IN181897B (zh)
MX (1) MX9707611A (zh)
MY (1) MY132116A (zh)
NO (1) NO974562L (zh)
NZ (1) NZ305735A (zh)
PE (1) PE39097A1 (zh)
PL (1) PL322821A1 (zh)
TR (1) TR199701122T1 (zh)
UA (1) UA46759C2 (zh)
WO (1) WO1996031228A1 (zh)
YU (1) YU22496A (zh)
ZA (1) ZA962598B (zh)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6384013B1 (en) 1992-03-19 2002-05-07 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
US5965525A (en) * 1992-03-19 1999-10-12 Eli Lilly And Company Cyclic peptide antifungal agents
US6743777B1 (en) * 1992-03-19 2004-06-01 Eli Lilly And Company Cyclic peptide antifungal agents and process for preparation thereof
EP0881907A4 (en) * 1996-02-01 2000-05-10 Lilly Co Eli FUNGICIDES IN THE FORM OF CYCLIC PEPTIDES
AU8687798A (en) * 1997-08-04 1999-02-22 Eli Lilly And Company Cyclic peptide antifungal agents
FR2784993B1 (fr) * 1998-10-26 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme fongicides
AU2003200556B2 (en) * 1997-12-10 2005-12-01 Novexel Echinocandin derivative and their preparation method
UA72200C2 (uk) 1997-12-10 2005-02-15 Авентіс Фарма С.А. Похідні ехінокандину, спосіб їх одержання, їх застосування, проміжні сполуки та фармацевтична композиція
US6323176B1 (en) 1998-02-25 2001-11-27 Eli Lilly And Company Cyclic peptide antifungal agents
MA26663A1 (fr) 1998-07-23 2004-12-20 Hoffmann La Roche Nouvelles aerothricines et leurs applications antifongiques
ATE287899T1 (de) 1998-08-20 2005-02-15 Lilly Co Eli Verfahren zur herstellung von ring-modifizierten zyklischen peptidanalogen
EP1137663B1 (en) 1998-12-09 2006-08-30 Eli Lilly And Company Purification of echinocandin cyclopeptide compounds
DE60019902D1 (de) * 1999-03-03 2005-06-09 Lilly Co Eli Echinocandin pharmazeutische zusammensetzungen
PT1157030E (pt) * 1999-03-03 2004-01-30 Lilly Co Eli Complexos equinocandina/hidrato de carbono
CA2362826A1 (en) 1999-03-03 2000-09-08 Michael Anthony Dotlich Formation and anion-exchange of crystalline echinocandin ammonium salts
JP2002538097A (ja) 1999-03-03 2002-11-12 イーライ リリー アンド カンパニー 薬学的経口ｅｃｂ処方物および組成物の作製方法
FR2794747B1 (fr) * 1999-06-09 2004-04-16 Hoechst Marion Roussel Inc Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme anti-fongiques
EP1254161B1 (en) 2000-01-17 2005-04-20 Basilea Pharmaceutica AG Aerothricin analogs, their preparation and use
FR2833596B1 (fr) * 2001-12-14 2005-02-18 Aventis Pharma Sa Procede de preparation de derives d'echinocandine
US6991800B2 (en) * 2002-06-13 2006-01-31 Vicuron Pharmaceuticals Inc. Antifungal parenteral products
CN101602795B (zh) * 2009-07-20 2011-12-21 中国人民解放军第二军医大学 环六脂肽胺类抗真菌化合物及其盐类和制备方法
CN103570530B (zh) * 2012-07-26 2016-08-10 鲁南新时代生物技术有限公司 一种阿尼芬净侧链中间体的制备方法
CN104003895B (zh) * 2014-05-29 2016-02-24 黑龙江大学 一种钯催化的串联反应合成三联苯类化合物的方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4293488A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912B nucleus
US4293489A (en) * 1979-12-13 1981-10-06 Eli Lilly And Company Derivatives of A-30912A nucleus
US4320052A (en) * 1979-12-13 1982-03-16 Eli Lilly And Company Derivatives of A-30912A nucleus
US5166135A (en) * 1988-09-12 1992-11-24 Merck & Company, Inc. Method for the control of pneumocystis carinii
DK173802B1 (da) * 1988-09-12 2001-11-05 Merck & Co Inc Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner
CA2037957A1 (en) * 1990-03-12 1991-09-13 Merck & Co., Inc. N-acylated cyclohexapeptide compounds
GB2241956A (en) * 1990-03-16 1991-09-18 Merck & Co Inc N-acylated cyclohexapeptide compounds
US5330973A (en) * 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
US5386009A (en) * 1990-03-19 1995-01-31 Merck & Co. Inc. Lipopeptide derivatives
US5310726A (en) * 1990-03-19 1994-05-10 Merck & Co., Inc. Lipopeptide compounds
IL97347A0 (en) * 1990-03-19 1992-05-25 Merck & Co Inc Lipopeptide derivatives and antimicrobial compositions containing them
US5049546A (en) * 1990-03-19 1991-09-17 Merck & Co., Inc. Antibiotic agents
IE910892A1 (en) * 1990-03-19 1991-09-25 Merck & Co Inc Lipopeptide compounds
IE990233A1 (en) * 1990-06-18 2000-11-15 Fujisawa Pharmaceutical Co New Polypeptide Compound and a Process for Preparation thereof
EP0486011A3 (en) * 1990-11-16 1992-07-15 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical composition against pneumocystis carinii
US5369093A (en) * 1991-03-15 1994-11-29 Merck & Co., Inc. Lipopeptide derivatives
US5233023A (en) * 1991-07-30 1993-08-03 Merck & Co., Inc. Process for phosphate ester compounds of certain cyclohexapeptides
NZ299314A (en) * 1992-03-19 2001-09-28 Lilly Co Eli Cyclic peptide for inhibiting parasitic and antifungal activity

Also Published As

Publication number Publication date
WO1996031228A1 (en) 1996-10-10
NO974562D0 (no) 1997-10-02
HUP9800809A3 (en) 1998-12-28
AR002731A1 (es) 1998-04-29
EP0736541B1 (en) 2002-11-27
AU702841B2 (en) 1999-03-04
PL322821A1 (en) 1998-02-16
EP0736541A1 (en) 1996-10-09
IL117749A0 (en) 1996-08-04
YU22496A (sh) 1999-06-15
NZ305735A (en) 1999-01-28
ZA962598B (en) 1997-10-01
UA46759C2 (uk) 2002-06-17
EA000464B1 (ru) 1999-08-26
CA2217048A1 (en) 1996-10-10
DE69624966D1 (de) 2003-01-09
JPH11504005A (ja) 1999-04-06
KR19980703646A (ko) 1998-12-05
MY132116A (en) 2007-09-28
HUP9800809A2 (hu) 1998-08-28
CZ291702B6 (cs) 2003-05-14
CZ310297A3 (cs) 1998-06-17
CO4700480A1 (es) 1998-12-29
ES2187617T3 (es) 2003-06-16
EA199700307A1 (ru) 1998-04-30
IN181897B (zh) 1998-10-24
AU5383496A (en) 1996-10-23
CN1185739A (zh) 1998-06-24
AR004170A1 (es) 1998-11-04
PE39097A1 (es) 1997-10-13
US5646111A (en) 1997-07-08
ATE228535T1 (de) 2002-12-15
DE69624966T2 (de) 2003-03-27
NO974562L (no) 1997-11-28
TR199701122T1 (xx) 1998-02-21
MX9707611A (es) 1997-12-31
BR9604906A (pt) 1998-07-21

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees