IL117749A - Cyclic peptides process for their preparation and antifungal compositions containing them - Google Patents
Cyclic peptides process for their preparation and antifungal compositions containing themInfo
- Publication number
- IL117749A IL117749A IL11774996A IL11774996A IL117749A IL 117749 A IL117749 A IL 117749A IL 11774996 A IL11774996 A IL 11774996A IL 11774996 A IL11774996 A IL 11774996A IL 117749 A IL117749 A IL 117749A
- Authority
- IL
- Israel
- Prior art keywords
- preparation
- compositions containing
- cyclic peptides
- antifungal compositions
- peptides process
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Oncology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US41834195A | 1995-04-07 | 1995-04-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
IL117749A0 IL117749A0 (en) | 1996-08-04 |
IL117749A true IL117749A (en) | 2000-06-01 |
Family
ID=23657711
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11774996A IL117749A (en) | 1995-04-07 | 1996-04-01 | Cyclic peptides process for their preparation and antifungal compositions containing them |
Country Status (29)
Country | Link |
---|---|
US (1) | US5646111A (zh) |
EP (1) | EP0736541B1 (zh) |
JP (1) | JPH11504005A (zh) |
KR (1) | KR19980703646A (zh) |
CN (1) | CN1185739A (zh) |
AR (2) | AR004170A1 (zh) |
AT (1) | ATE228535T1 (zh) |
AU (1) | AU702841B2 (zh) |
BR (1) | BR9604906A (zh) |
CA (1) | CA2217048A1 (zh) |
CO (1) | CO4700480A1 (zh) |
CZ (1) | CZ291702B6 (zh) |
DE (1) | DE69624966T2 (zh) |
EA (1) | EA000464B1 (zh) |
ES (1) | ES2187617T3 (zh) |
HU (1) | HUP9800809A3 (zh) |
IL (1) | IL117749A (zh) |
IN (1) | IN181897B (zh) |
MX (1) | MX9707611A (zh) |
MY (1) | MY132116A (zh) |
NO (1) | NO974562L (zh) |
NZ (1) | NZ305735A (zh) |
PE (1) | PE39097A1 (zh) |
PL (1) | PL322821A1 (zh) |
TR (1) | TR199701122T1 (zh) |
UA (1) | UA46759C2 (zh) |
WO (1) | WO1996031228A1 (zh) |
YU (1) | YU22496A (zh) |
ZA (1) | ZA962598B (zh) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6384013B1 (en) | 1992-03-19 | 2002-05-07 | Eli Lilly And Company | Cyclic peptide antifungal agents and process for preparation thereof |
US5965525A (en) * | 1992-03-19 | 1999-10-12 | Eli Lilly And Company | Cyclic peptide antifungal agents |
US6743777B1 (en) * | 1992-03-19 | 2004-06-01 | Eli Lilly And Company | Cyclic peptide antifungal agents and process for preparation thereof |
EP0881907A4 (en) * | 1996-02-01 | 2000-05-10 | Lilly Co Eli | FUNGICIDES IN THE FORM OF CYCLIC PEPTIDES |
AU8687798A (en) * | 1997-08-04 | 1999-02-22 | Eli Lilly And Company | Cyclic peptide antifungal agents |
FR2784993B1 (fr) * | 1998-10-26 | 2002-10-31 | Hoechst Marion Roussel Inc | Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme fongicides |
AU2003200556B2 (en) * | 1997-12-10 | 2005-12-01 | Novexel | Echinocandin derivative and their preparation method |
UA72200C2 (uk) | 1997-12-10 | 2005-02-15 | Авентіс Фарма С.А. | Похідні ехінокандину, спосіб їх одержання, їх застосування, проміжні сполуки та фармацевтична композиція |
US6323176B1 (en) | 1998-02-25 | 2001-11-27 | Eli Lilly And Company | Cyclic peptide antifungal agents |
MA26663A1 (fr) | 1998-07-23 | 2004-12-20 | Hoffmann La Roche | Nouvelles aerothricines et leurs applications antifongiques |
ATE287899T1 (de) | 1998-08-20 | 2005-02-15 | Lilly Co Eli | Verfahren zur herstellung von ring-modifizierten zyklischen peptidanalogen |
EP1137663B1 (en) | 1998-12-09 | 2006-08-30 | Eli Lilly And Company | Purification of echinocandin cyclopeptide compounds |
DE60019902D1 (de) * | 1999-03-03 | 2005-06-09 | Lilly Co Eli | Echinocandin pharmazeutische zusammensetzungen |
PT1157030E (pt) * | 1999-03-03 | 2004-01-30 | Lilly Co Eli | Complexos equinocandina/hidrato de carbono |
CA2362826A1 (en) | 1999-03-03 | 2000-09-08 | Michael Anthony Dotlich | Formation and anion-exchange of crystalline echinocandin ammonium salts |
JP2002538097A (ja) | 1999-03-03 | 2002-11-12 | イーライ リリー アンド カンパニー | 薬学的経口ecb処方物および組成物の作製方法 |
FR2794747B1 (fr) * | 1999-06-09 | 2004-04-16 | Hoechst Marion Roussel Inc | Nouveaux derives de l'echinocandine, leur procede de preparation et leur application comme anti-fongiques |
EP1254161B1 (en) | 2000-01-17 | 2005-04-20 | Basilea Pharmaceutica AG | Aerothricin analogs, their preparation and use |
FR2833596B1 (fr) * | 2001-12-14 | 2005-02-18 | Aventis Pharma Sa | Procede de preparation de derives d'echinocandine |
US6991800B2 (en) * | 2002-06-13 | 2006-01-31 | Vicuron Pharmaceuticals Inc. | Antifungal parenteral products |
CN101602795B (zh) * | 2009-07-20 | 2011-12-21 | 中国人民解放军第二军医大学 | 环六脂肽胺类抗真菌化合物及其盐类和制备方法 |
CN103570530B (zh) * | 2012-07-26 | 2016-08-10 | 鲁南新时代生物技术有限公司 | 一种阿尼芬净侧链中间体的制备方法 |
CN104003895B (zh) * | 2014-05-29 | 2016-02-24 | 黑龙江大学 | 一种钯催化的串联反应合成三联苯类化合物的方法 |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4293488A (en) * | 1979-12-13 | 1981-10-06 | Eli Lilly And Company | Derivatives of A-30912B nucleus |
US4293489A (en) * | 1979-12-13 | 1981-10-06 | Eli Lilly And Company | Derivatives of A-30912A nucleus |
US4320052A (en) * | 1979-12-13 | 1982-03-16 | Eli Lilly And Company | Derivatives of A-30912A nucleus |
US5166135A (en) * | 1988-09-12 | 1992-11-24 | Merck & Company, Inc. | Method for the control of pneumocystis carinii |
DK173802B1 (da) * | 1988-09-12 | 2001-11-05 | Merck & Co Inc | Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner |
CA2037957A1 (en) * | 1990-03-12 | 1991-09-13 | Merck & Co., Inc. | N-acylated cyclohexapeptide compounds |
GB2241956A (en) * | 1990-03-16 | 1991-09-18 | Merck & Co Inc | N-acylated cyclohexapeptide compounds |
US5330973A (en) * | 1990-03-19 | 1994-07-19 | Merck & Co., Inc. | Lipopeptide derivatives |
US5386009A (en) * | 1990-03-19 | 1995-01-31 | Merck & Co. Inc. | Lipopeptide derivatives |
US5310726A (en) * | 1990-03-19 | 1994-05-10 | Merck & Co., Inc. | Lipopeptide compounds |
IL97347A0 (en) * | 1990-03-19 | 1992-05-25 | Merck & Co Inc | Lipopeptide derivatives and antimicrobial compositions containing them |
US5049546A (en) * | 1990-03-19 | 1991-09-17 | Merck & Co., Inc. | Antibiotic agents |
IE910892A1 (en) * | 1990-03-19 | 1991-09-25 | Merck & Co Inc | Lipopeptide compounds |
IE990233A1 (en) * | 1990-06-18 | 2000-11-15 | Fujisawa Pharmaceutical Co | New Polypeptide Compound and a Process for Preparation thereof |
EP0486011A3 (en) * | 1990-11-16 | 1992-07-15 | Fujisawa Pharmaceutical Co., Ltd. | Pharmaceutical composition against pneumocystis carinii |
US5369093A (en) * | 1991-03-15 | 1994-11-29 | Merck & Co., Inc. | Lipopeptide derivatives |
US5233023A (en) * | 1991-07-30 | 1993-08-03 | Merck & Co., Inc. | Process for phosphate ester compounds of certain cyclohexapeptides |
NZ299314A (en) * | 1992-03-19 | 2001-09-28 | Lilly Co Eli | Cyclic peptide for inhibiting parasitic and antifungal activity |
-
1996
- 1996-03-07 US US08/612,208 patent/US5646111A/en not_active Expired - Fee Related
- 1996-04-01 ZA ZA9602598A patent/ZA962598B/xx unknown
- 1996-04-01 PE PE1996000229A patent/PE39097A1/es not_active Application Discontinuation
- 1996-04-01 IL IL11774996A patent/IL117749A/xx not_active IP Right Cessation
- 1996-04-02 IN IN591CA1996 patent/IN181897B/en unknown
- 1996-04-03 AU AU53834/96A patent/AU702841B2/en not_active Ceased
- 1996-04-03 NZ NZ305735A patent/NZ305735A/xx unknown
- 1996-04-03 HU HU9800809A patent/HUP9800809A3/hu unknown
- 1996-04-03 DE DE69624966T patent/DE69624966T2/de not_active Expired - Fee Related
- 1996-04-03 CO CO96016384A patent/CO4700480A1/es unknown
- 1996-04-03 EA EA199700307A patent/EA000464B1/ru not_active IP Right Cessation
- 1996-04-03 PL PL96322821A patent/PL322821A1/xx unknown
- 1996-04-03 TR TR97/01122T patent/TR199701122T1/xx unknown
- 1996-04-03 CZ CZ19973102A patent/CZ291702B6/cs not_active IP Right Cessation
- 1996-04-03 ES ES96302362T patent/ES2187617T3/es not_active Expired - Lifetime
- 1996-04-03 UA UA97104915A patent/UA46759C2/uk unknown
- 1996-04-03 CN CN96194199A patent/CN1185739A/zh active Pending
- 1996-04-03 JP JP8530439A patent/JPH11504005A/ja not_active Ceased
- 1996-04-03 EP EP96302362A patent/EP0736541B1/en not_active Expired - Lifetime
- 1996-04-03 MX MX9707611A patent/MX9707611A/es unknown
- 1996-04-03 AR ARP960102058A patent/AR004170A1/es not_active Application Discontinuation
- 1996-04-03 BR BR9604906A patent/BR9604906A/pt not_active IP Right Cessation
- 1996-04-03 KR KR1019970707045A patent/KR19980703646A/ko not_active Application Discontinuation
- 1996-04-03 AT AT96302362T patent/ATE228535T1/de not_active IP Right Cessation
- 1996-04-03 WO PCT/US1996/004543 patent/WO1996031228A1/en not_active Application Discontinuation
- 1996-04-03 CA CA002217048A patent/CA2217048A1/en not_active Abandoned
- 1996-04-03 AR ARP960102057A patent/AR002731A1/es unknown
- 1996-04-05 YU YU22496A patent/YU22496A/sh unknown
- 1996-04-06 MY MYPI96001310A patent/MY132116A/en unknown
-
1997
- 1997-10-02 NO NO974562A patent/NO974562L/no not_active Application Discontinuation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
MM9K | Patent not in force due to non-payment of renewal fees |