IL115059A - Pharmaceutical composition for oral administration comprising a combination of ramipril and a dihydropyridine compound - Google Patents
Pharmaceutical composition for oral administration comprising a combination of ramipril and a dihydropyridine compoundInfo
- Publication number
- IL115059A IL115059A IL11505995A IL11505995A IL115059A IL 115059 A IL115059 A IL 115059A IL 11505995 A IL11505995 A IL 11505995A IL 11505995 A IL11505995 A IL 11505995A IL 115059 A IL115059 A IL 115059A
- Authority
- IL
- Israel
- Prior art keywords
- pharmaceutical composition
- pct
- combination
- ramipril
- oral administration
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/556—Angiotensin converting enzyme inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9402924A SE9402924D0 (sv) | 1994-09-02 | 1994-09-02 | Novel pharmaceutical composition |
SE9402925A SE9402925D0 (sv) | 1994-09-02 | 1994-09-02 | Novel oral pharmaceutical composition |
Publications (2)
Publication Number | Publication Date |
---|---|
IL115059A0 IL115059A0 (en) | 1996-01-19 |
IL115059A true IL115059A (en) | 2003-10-31 |
Family
ID=26662130
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IL11505995A IL115059A (en) | 1994-09-02 | 1995-08-24 | Pharmaceutical composition for oral administration comprising a combination of ramipril and a dihydropyridine compound |
Country Status (33)
Country | Link |
---|---|
US (1) | US6086919A (sk) |
EP (1) | EP0726766B1 (sk) |
JP (1) | JP3776931B2 (sk) |
KR (1) | KR100438133B1 (sk) |
CN (1) | CN1134665A (sk) |
AT (1) | ATE217187T1 (sk) |
AU (1) | AU695865B2 (sk) |
CA (1) | CA2174338C (sk) |
CZ (1) | CZ292224B6 (sk) |
DE (2) | DE726766T1 (sk) |
DK (1) | DK0726766T3 (sk) |
EE (1) | EE03550B1 (sk) |
EG (1) | EG24435A (sk) |
ES (1) | ES2091173T3 (sk) |
FI (1) | FI117616B (sk) |
GR (1) | GR960300055T1 (sk) |
HK (1) | HK1001811A1 (sk) |
HU (1) | HU226894B1 (sk) |
IL (1) | IL115059A (sk) |
IS (1) | IS1781B (sk) |
MX (1) | MX9601586A (sk) |
MY (1) | MY119489A (sk) |
NO (1) | NO308694B1 (sk) |
NZ (2) | NZ292298A (sk) |
PL (1) | PL186745B1 (sk) |
PT (1) | PT726766E (sk) |
RU (1) | RU2184563C2 (sk) |
SA (1) | SA95160287B1 (sk) |
SI (1) | SI0726766T1 (sk) |
SK (1) | SK283633B6 (sk) |
TR (1) | TR199501077A2 (sk) |
TW (1) | TW483763B (sk) |
WO (1) | WO1996007400A1 (sk) |
Families Citing this family (53)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19715594A1 (de) | 1997-04-15 | 1998-10-22 | Bayer Ag | Analgetika-Kombination |
AU1042199A (en) * | 1998-11-06 | 2000-05-29 | Boehringer Ingelheim International Gmbh | Antihypertensive medicaments containing lacidipine and telmisartan |
PE20001302A1 (es) * | 1998-11-27 | 2000-11-30 | Hoffmann La Roche | Preparaciones de una combinacion farmaceutica que contiene carvedilol e hidroclorotiazida |
KR100356374B1 (ko) * | 2000-09-14 | 2002-10-19 | 사회복지법인삼성생명공익재단(삼성서울병원) | 안지오텐신 전환효소 억제제의 부작용으로 발생하는마른기침을 저해하기 위한 철분을 포함하는 기침 저해조성물 |
CA2357982A1 (en) * | 2001-09-28 | 2003-03-28 | Bernard Charles Sherman | Solid compositions comprising ramipril |
MXPA04006892A (es) * | 2002-01-15 | 2004-10-15 | Ranbaxy Lab Ltd | Composiciones farmaceuticas estables que comprenden inhibidor(es) ace. |
US6844361B2 (en) * | 2002-02-04 | 2005-01-18 | Aventis Pharma Deutschland Gmbh | Pharmaceutical composition comprising a sodium hydrogen exchange inhibitor and an angiotensin converting enzyme inhibitor |
US20030175342A1 (en) * | 2002-03-14 | 2003-09-18 | Karl Kolter | Coated pharmaceutical single-unit delayed-release forms, based on polyvinyl acetate |
US20030211149A1 (en) * | 2002-05-07 | 2003-11-13 | Sherman Bernard Charles | Extended release tablets comprising felodipine |
US6663892B1 (en) | 2002-08-19 | 2003-12-16 | L. Perrigo Company | Multiple portion tablet |
US20050101640A1 (en) * | 2002-10-16 | 2005-05-12 | Recordati Ireland Limited | Lisinopril/lercanidipine combination therapy |
US20040147566A1 (en) * | 2002-10-16 | 2004-07-29 | Amedeo Leonardi | Lisinopril/lercanidipine combination therapy |
BR0317028A (pt) * | 2002-12-10 | 2005-10-25 | Novartis Ag | Combinação de um inibidor de dpp-iv e um composto de ppar-alfa |
GB0301471D0 (en) * | 2003-01-22 | 2003-02-19 | Biochemie Gmbh | Organic compounds |
DK1635792T3 (da) * | 2003-06-26 | 2009-06-15 | Teva Pharma | Stabile farmaceutiske sammensætninger af 2-aza-bicyklo-3.3.0-oktan-3-carboxylsyrederivater |
AU2004275777A1 (en) * | 2003-09-24 | 2005-04-07 | Combinatorx, Incorporated | Therapeutic regimens for administering drug combinations |
DE102004008804A1 (de) * | 2004-02-20 | 2005-09-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Mehrschichttablette |
GB2411355B (en) | 2004-02-27 | 2006-02-22 | Niche Generics Ltd | Pharmaceutical composition |
TW200534879A (en) * | 2004-03-25 | 2005-11-01 | Bristol Myers Squibb Co | Coated tablet formulation and method |
US7829720B2 (en) * | 2004-05-04 | 2010-11-09 | Bristol-Myers Squibb Company | Process for preparing atazanavir bisulfate and novel forms |
US20050256314A1 (en) * | 2004-05-04 | 2005-11-17 | Soojin Kim | Process employing controlled crystallization in forming crystals of a pharmaceutical |
US20050288343A1 (en) * | 2004-05-19 | 2005-12-29 | Andrew Rusowicz | Process of preparing substituted carbamates and intermediates thereof |
US7622137B2 (en) * | 2004-05-21 | 2009-11-24 | Accu-Break Technologies, Inc. | Dosage forms contained within a capsule or sachet |
US7838031B2 (en) | 2004-05-21 | 2010-11-23 | Lawrence Solomon | Method of administering a partial dose using a segmented pharmaceutical tablet |
US7780985B2 (en) * | 2005-07-12 | 2010-08-24 | Accu-Break Technologies, Inc. | Tablets having a printed separation mark to guide breaking |
WO2005112898A1 (en) * | 2004-05-21 | 2005-12-01 | Accu-Break Pharmaceuticals, Inc. | Pharmaceutical tablets having a relatively inactive segment |
US7318935B2 (en) * | 2004-05-21 | 2008-01-15 | Accu-Break Technologies, Inc. | Pharmaceutical tablets with active and inactive segments |
US7713547B2 (en) | 2004-05-21 | 2010-05-11 | Accu-Break Pharmaceuticals, Inc. | Method of administering a partial dose of a segmented pharmaceutical tablet |
US7329418B2 (en) * | 2004-05-21 | 2008-02-12 | Accu Break Technologies, Inc. | Pharmaceutical tablets having height greater than width |
TWI415635B (zh) * | 2004-05-28 | 2013-11-21 | 必治妥施貴寶公司 | 加衣錠片調製物及製備彼之方法 |
KR100593795B1 (ko) | 2004-10-12 | 2006-06-30 | 대원제약주식회사 | 안정성이 개선된 라미프릴을 포함하는 경구투여용 제제 |
CA2586547A1 (en) * | 2004-11-05 | 2006-05-11 | King Pharmaceuticals Research & Development, Inc. | Stabilized individually coated ramipril particles, compositions and methods |
KR100714616B1 (ko) * | 2005-06-23 | 2007-05-07 | 삼성전기주식회사 | 지수 함수 발생기 및 이를 이용한 가변 이득 증폭기 |
BRPI0614417A2 (pt) * | 2005-07-28 | 2011-03-29 | Reliant Pharmaceuticals Inc | composições farmacêuticas compreendendo bloqueadores de canais de cálcio de dihidropiridina e ácidos graxos de Èmega-3 e métodos de tratamento utilizando as mesmas |
EP1948136A1 (en) * | 2005-11-07 | 2008-07-30 | King Pharmaceuticals Research and Development, Inc. | Compositions of stabilized ramipril in combination with another active agent |
JP5259413B2 (ja) * | 2005-11-18 | 2013-08-07 | エーシーシーユー−ブレイク テクノロジーズ,インク. | セグメント化した薬の剤形 |
US20070237815A1 (en) * | 2006-04-06 | 2007-10-11 | Lawrence Solomon | Dosage forms and methods comprising amlodipine and chlorthalidone |
RU2008145115A (ru) * | 2006-04-19 | 2010-05-27 | Тева Фармасьютикл Индастриес Лтд. (Il) | Стабильные фармацевтические композиции производственных соединений 2-аза-бицикло[3.3.0]-октан-3-карбоновой кислоты |
CA2671200A1 (en) * | 2006-07-21 | 2008-01-24 | Lab International Srl | Hydrophilic abuse deterrent delivery system |
US20110086092A1 (en) * | 2006-08-08 | 2011-04-14 | Accu-Break Technologies, Inc. | Pharmacuetical tablets containing a plurality of active ingredients |
JP2010511627A (ja) * | 2006-11-30 | 2010-04-15 | エーシーシーユー−ブレイク テクノロジーズ,インク. | 分割可能な浸透性剤形及びその使用方法 |
GB0624087D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril combination salt |
GB0624084D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril amino acid salts |
GB0624090D0 (en) * | 2006-12-01 | 2007-01-10 | Selamine Ltd | Ramipril amine salts |
SI2178513T1 (sl) * | 2007-06-22 | 2011-05-31 | Bristol Myers Squibb Co | Tabletni sestavki vsebujoäśi atazanavir |
EP2178512B1 (en) * | 2007-06-22 | 2011-03-09 | Bristol-Myers Squibb Company | Tableted compositions containing atazanavir |
DE602008005316D1 (de) * | 2007-06-22 | 2011-04-14 | Bristol Myers Squibb Co | Tablettierte atazanavirhaltige zusammensetzungen |
PT2170292E (pt) * | 2007-06-22 | 2014-03-06 | Bristol Myers Squibb Holdings Ireland | Composições de comprimido contendo atazanavir |
EP2249815B1 (en) * | 2008-01-25 | 2020-06-24 | Laboratoires Majorelle | Combinations of oral medicaments bonded by a wrapping |
PE20110591A1 (es) | 2008-07-28 | 2011-09-15 | Takeda Pharmaceutical | Composicion farmaceutica estabilizada a base de un compuesto no peptidico |
DE102008059206A1 (de) | 2008-11-27 | 2010-06-10 | Bayer Schering Pharma Aktiengesellschaft | Pharmazeutische Darreichungsform enthaltend Nifedipin oder Nisoldipin und einen Angiotensin-II Antagonisten und/oder ein Diuretikum |
SI23149A (sl) | 2009-09-21 | 2011-03-31 | Silverstone Pharma | Nove benzatinske soli ACE inhibitorjev, postopek za njihovo pripravo in njihova uporaba za zdravljenje kardiovaskularnih bolezni |
CN101843892B (zh) * | 2010-05-18 | 2013-03-06 | 广州白云山制药股份有限公司广州白云山制药总厂 | 包括依那普利速释部分和非洛地平缓释部分的药物组合物制剂 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1670827C3 (de) * | 1967-03-20 | 1974-10-24 | Bayer Ag, 5090 Leverkusen | 4-(2'-Nitrophenyl)-2,6-dimethyl-3,5-dicarbmethoxy-1,4-dihydropyridin |
DE2117571C3 (de) * | 1971-04-10 | 1979-10-11 | Bayer Ag, 5090 Leverkusen | Unsymmetrische 1,4-Dihydropyridin-33-dicarbonsäureester, Verfahren zu ihrer Herstellung sowie ihre Verwendung als Arzneimittel |
SE429652B (sv) * | 1978-06-30 | 1983-09-19 | Haessle Ab | 2.6-dimetyl-4-(2.3-diklorfenyl)-1.4-dihydropyridin-3.5-dikarboxylsyra-3-metylester-5-etylester |
DE3413710A1 (de) * | 1984-04-12 | 1985-10-24 | Hoechst Ag, 6230 Frankfurt | Verfahren zur behandlung der herzinsuffizienz |
NZ212895A (en) * | 1984-08-22 | 1988-07-28 | Glaxo Spa | 1,4-dihydropyridine derivatives and pharmaceutical compositions |
DE3437917A1 (de) * | 1984-10-17 | 1986-04-17 | Bayer Ag, 5090 Leverkusen | Kombination von dihydropyridinen mit ace-hemmern sowie ihre verwendung in arzneimitteln |
DE3633496A1 (de) * | 1986-10-02 | 1988-04-14 | Hoechst Ag | Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln |
DE3704661A1 (de) * | 1987-02-14 | 1988-08-25 | Hoechst Ag | Annelierte azepinon- und azocinon-derivate, verfahren zu ihrer herstellung, diese enthaltende mittel und ihre verwendung, sowie zwischenprodukte bei ihrer herstellung |
US4743450A (en) * | 1987-02-24 | 1988-05-10 | Warner-Lambert Company | Stabilized compositions |
CA1323833C (en) * | 1987-04-28 | 1993-11-02 | Yatindra M. Joshi | Pharmaceutical compositions in the form of beadlets and method |
DE3739690A1 (de) * | 1987-11-24 | 1989-06-08 | Hoechst Ag | Stabilisierte arzneistoffe, verfahren zu ihrer herstellung sowie stabile arzneizubereitungen |
TW197945B (sk) * | 1990-11-27 | 1993-01-11 | Hoechst Ag | |
DE4109134A1 (de) * | 1991-03-20 | 1992-09-24 | Knoll Ag | Erzeugnisse, enthaltend verapamil und trandolapril |
CA2070085A1 (en) * | 1991-05-31 | 1992-12-01 | Gerald P. Polli | Ace inhibitor and calcium channel blocker for use in treating hypertension |
US5160744A (en) * | 1991-06-27 | 1992-11-03 | Alza Corporation | Verapmil therapy |
US5178867A (en) * | 1991-08-19 | 1993-01-12 | Alza Corporation | Dosage form for delivering drug in short-time period |
PT804229E (pt) * | 1995-03-16 | 2003-06-30 | Pfizer | Utilizacao de amlodipina de um dos seus sais ou defelodipina em combinacao com um inibidor da en zima de conversao da angiotensina (ace) para no fabrico de um medicamento destinado ao tratamento da insuficiencia cardiaca congestiva nao isquemica |
-
1995
- 1995-08-21 TW TW084108719A patent/TW483763B/zh not_active IP Right Cessation
- 1995-08-24 MY MYPI95002506A patent/MY119489A/en unknown
- 1995-08-24 IL IL11505995A patent/IL115059A/xx not_active IP Right Cessation
- 1995-08-29 TR TR95/01077A patent/TR199501077A2/xx unknown
- 1995-08-30 JP JP50941696A patent/JP3776931B2/ja not_active Expired - Lifetime
- 1995-08-30 DE DE0726766T patent/DE726766T1/de active Pending
- 1995-08-30 SK SK558-96A patent/SK283633B6/sk not_active IP Right Cessation
- 1995-08-30 DE DE69526640T patent/DE69526640T2/de not_active Expired - Lifetime
- 1995-08-30 PL PL95314084A patent/PL186745B1/pl unknown
- 1995-08-30 CZ CZ19961173A patent/CZ292224B6/cs not_active IP Right Cessation
- 1995-08-30 AT AT95930771T patent/ATE217187T1/de active
- 1995-08-30 DK DK95930771T patent/DK0726766T3/da active
- 1995-08-30 US US08/522,267 patent/US6086919A/en not_active Expired - Lifetime
- 1995-08-30 NZ NZ292298A patent/NZ292298A/en not_active IP Right Cessation
- 1995-08-30 AU AU34029/95A patent/AU695865B2/en not_active Expired
- 1995-08-30 HU HU9601146A patent/HU226894B1/hu unknown
- 1995-08-30 ES ES95930771T patent/ES2091173T3/es not_active Expired - Lifetime
- 1995-08-30 KR KR1019960702254A patent/KR100438133B1/ko active IP Right Grant
- 1995-08-30 SI SI9530603T patent/SI0726766T1/xx unknown
- 1995-08-30 EP EP95930771A patent/EP0726766B1/en not_active Expired - Lifetime
- 1995-08-30 CA CA002174338A patent/CA2174338C/en not_active Expired - Lifetime
- 1995-08-30 PT PT95930771T patent/PT726766E/pt unknown
- 1995-08-30 WO PCT/SE1995/000972 patent/WO1996007400A1/en active IP Right Grant
- 1995-08-30 RU RU96112139/14A patent/RU2184563C2/ru active
- 1995-08-30 CN CN95190823A patent/CN1134665A/zh active Pending
- 1995-08-30 EE EE9600072A patent/EE03550B1/xx unknown
- 1995-08-31 EG EG73295A patent/EG24435A/xx active
- 1995-10-03 SA SA95160287A patent/SA95160287B1/ar unknown
-
1996
- 1996-04-18 IS IS4337A patent/IS1781B/is unknown
- 1996-04-29 MX MX9601586A patent/MX9601586A/es unknown
- 1996-04-29 NO NO961726A patent/NO308694B1/no not_active IP Right Cessation
- 1996-05-02 FI FI961863A patent/FI117616B/fi not_active IP Right Cessation
- 1996-10-31 GR GR960300055T patent/GR960300055T1/el unknown
-
1998
- 1998-01-08 NZ NZ329556A patent/NZ329556A/xx not_active IP Right Cessation
- 1998-02-05 HK HK98100840A patent/HK1001811A1/xx not_active IP Right Cessation
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FF | Patent granted | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
KB | Patent renewed | ||
EXP | Patent expired |