IL115040A - Substituted piperidines useful for the treatment of allergic diseases process for their preparation and pharmaceutical compositions containing them - Google Patents

Substituted piperidines useful for the treatment of allergic diseases process for their preparation and pharmaceutical compositions containing them

Info

Publication number
IL115040A
IL115040A IL11504095A IL11504095A IL115040A IL 115040 A IL115040 A IL 115040A IL 11504095 A IL11504095 A IL 11504095A IL 11504095 A IL11504095 A IL 11504095A IL 115040 A IL115040 A IL 115040A
Authority
IL
Israel
Prior art keywords
treatment
allergic diseases
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL11504095A
Other languages
English (en)
Other versions
IL115040A0 (en
Original Assignee
Merrell Dow Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merrell Dow Pharma filed Critical Merrell Dow Pharma
Publication of IL115040A0 publication Critical patent/IL115040A0/xx
Publication of IL115040A publication Critical patent/IL115040A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
IL11504095A 1994-08-25 1995-08-23 Substituted piperidines useful for the treatment of allergic diseases process for their preparation and pharmaceutical compositions containing them IL115040A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29596094A 1994-08-25 1994-08-25
US50191495A 1995-07-13 1995-07-13

Publications (2)

Publication Number Publication Date
IL115040A0 IL115040A0 (en) 1995-12-08
IL115040A true IL115040A (en) 2000-02-29

Family

ID=26969426

Family Applications (1)

Application Number Title Priority Date Filing Date
IL11504095A IL115040A (en) 1994-08-25 1995-08-23 Substituted piperidines useful for the treatment of allergic diseases process for their preparation and pharmaceutical compositions containing them

Country Status (20)

Country Link
US (1) US6329392B1 (zh)
EP (1) EP0777666B1 (zh)
JP (1) JPH10504580A (zh)
KR (1) KR100362620B1 (zh)
CN (1) CN1067385C (zh)
AT (1) ATE177095T1 (zh)
AU (1) AU693936B2 (zh)
CA (1) CA2198084C (zh)
DE (1) DE69508093T2 (zh)
DK (1) DK0777666T3 (zh)
ES (1) ES2132709T3 (zh)
FI (1) FI114470B (zh)
GR (1) GR3030253T3 (zh)
HU (1) HU221434B (zh)
IL (1) IL115040A (zh)
MX (1) MX9701305A (zh)
NO (1) NO313237B1 (zh)
NZ (1) NZ292683A (zh)
TW (1) TW430663B (zh)
WO (1) WO1996006094A1 (zh)

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US6194406B1 (en) 1995-12-20 2001-02-27 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic disease
ES2177827T3 (es) * 1995-12-20 2002-12-16 Aventis Pharma Inc 4-(1h-bencimidazol-2-il)(1,4)diazepanes utiles para el tratamiento de enfermedades alergicas.
US6423704B2 (en) 1995-12-20 2002-07-23 Aventis Pharmaceuticals Inc. Substituted 4-(1H-benzimidazol-2-yl)[1,4]diazepanes useful for the treatment of allergic diseases
CN1115341C (zh) * 1996-02-21 2003-07-23 阿温蒂斯药物公司 用于治疗过敏性疾病的新的取代的n－甲基－n－(4－(4－(1h－苯并咪唑－2－基氨基)哌啶－1－基)－2－(芳基)丁基)苯甲酰胺
KR19990087130A (ko) * 1996-02-21 1999-12-15 게리 디. 스트리트, 스티븐 엘. 네스비트 알레르기성 질환의 치료에 유용한 신규한 치환된 n-메틸-n-(4-(4-(1h-벤즈이미다졸-2-일)［1,4］디아제판-1-일)-2-(아릴)부틸)벤즈아미드
US5932571A (en) * 1996-02-21 1999-08-03 Hoechst Marion Roussel, Inc. Substituted N-methyl-N-(4-(4-(1H-benzimidazol-2-yl) {1,4}diazepan-1-yl)-2-(aryl) butyl) benzamides useful for the treatment of allergic diseases
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Also Published As

Publication number Publication date
TW430663B (en) 2001-04-21
US6329392B1 (en) 2001-12-11
CA2198084A1 (en) 1996-02-29
IL115040A0 (en) 1995-12-08
AU693936B2 (en) 1998-07-09
EP0777666B1 (en) 1999-03-03
WO1996006094A1 (en) 1996-02-29
DE69508093D1 (de) 1999-04-08
CN1067385C (zh) 2001-06-20
JPH10504580A (ja) 1998-05-06
KR100362620B1 (ko) 2003-02-14
EP0777666A1 (en) 1997-06-11
NZ292683A (en) 1998-07-28
FI970771A (fi) 1997-02-24
FI114470B (fi) 2004-10-29
MX9701305A (es) 1998-05-31
NO970831D0 (no) 1997-02-24
DK0777666T3 (da) 1999-09-27
GR3030253T3 (en) 1999-08-31
HUT76644A (en) 1997-10-28
ES2132709T3 (es) 1999-08-16
KR970705556A (ko) 1997-10-09
ATE177095T1 (de) 1999-03-15
AU3492895A (en) 1996-03-14
FI970771A0 (fi) 1997-02-24
DE69508093T2 (de) 1999-07-15
HU221434B (en) 2002-10-28
NO970831L (no) 1997-04-18
NO313237B1 (no) 2002-09-02
CA2198084C (en) 2000-03-28
CN1158612A (zh) 1997-09-03

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Legal Events

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FF Patent granted
MM9K Patent not in force due to non-payment of renewal fees
HC Change of name of proprietor(s)

Owner name: AVENTIS INC.

Free format text: FORMER NAME:MERRELL PHARMACEUTICALS INC.