IL107626A - Aqueous drug composition having property of reversible thermosetting gelation - Google Patents

Aqueous drug composition having property of reversible thermosetting gelation

Info

Publication number
IL107626A
IL107626A IL107626A IL10762693A IL107626A IL 107626 A IL107626 A IL 107626A IL 107626 A IL107626 A IL 107626A IL 10762693 A IL10762693 A IL 10762693A IL 107626 A IL107626 A IL 107626A
Authority
IL
Israel
Prior art keywords
property
drug composition
aqueous drug
reversible thermosetting
application
Prior art date
Application number
IL107626A
Other languages
English (en)
Other versions
IL107626A0 (en
Original Assignee
Wakamoto Pharma Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wakamoto Pharma Co Ltd filed Critical Wakamoto Pharma Co Ltd
Publication of IL107626A0 publication Critical patent/IL107626A0/xx
Publication of IL107626A publication Critical patent/IL107626A/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Thermotherapy And Cooling Therapy Devices (AREA)
IL107626A 1993-04-16 1993-11-16 Aqueous drug composition having property of reversible thermosetting gelation IL107626A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11234593 1993-04-16

Publications (2)

Publication Number Publication Date
IL107626A0 IL107626A0 (en) 1994-02-27
IL107626A true IL107626A (en) 1997-09-30

Family

ID=14584369

Family Applications (1)

Application Number Title Priority Date Filing Date
IL107626A IL107626A (en) 1993-04-16 1993-11-16 Aqueous drug composition having property of reversible thermosetting gelation

Country Status (17)

Country Link
US (1) US5624962A (sv)
EP (1) EP0694310B1 (sv)
KR (1) KR0162025B1 (sv)
CN (1) CN1048393C (sv)
AT (1) ATE189772T1 (sv)
AU (1) AU668447B2 (sv)
CA (1) CA2153234C (sv)
DE (1) DE69327878T2 (sv)
DK (1) DK0694310T3 (sv)
ES (1) ES2141775T3 (sv)
FI (1) FI112778B (sv)
HK (1) HK1017805A1 (sv)
HU (1) HU220864B1 (sv)
IL (1) IL107626A (sv)
NO (1) NO311635B1 (sv)
RU (1) RU2108112C1 (sv)
WO (1) WO1994023750A1 (sv)

Families Citing this family (77)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6436425B1 (en) 1988-11-16 2002-08-20 Mdv Technologies, Inc. Method and non-gelling composition for inhibiting post-surgical adhesions
US5346703A (en) 1990-08-07 1994-09-13 Mediventures, Inc. Body cavity drug delivery with thermo-irreversible polyoxyalkylene and ionic polysaccharide gels
US5318780A (en) * 1991-10-30 1994-06-07 Mediventures Inc. Medical uses of in situ formed gels
ZA952521B (en) * 1994-03-28 1996-03-15 Univ Columbia Composition for inactivating irritants in fluids
EP0782850A4 (en) * 1994-10-13 1998-03-04 Wakamoto Pharma Co Ltd LYOPHILIZED PREPARATION FOR PRODUCING A REVERSIBLE THERMOGELING MEDICINAL WATER-BASED
DE19511322C2 (de) 1995-03-28 1999-09-02 Mann Gerhard Chem Pharm Fab Sterile Augengele mit einem Gehalt an mittelkettigen Triglyceriden und Verfahren zu deren Herstellung
US5843470A (en) 1995-10-06 1998-12-01 Mdv Technologies, Inc. Method and composition for inhibiting post-surgical adhesions
CA2232855C (en) * 1997-04-10 2007-10-09 Roche Consumer Health (Worldwide) Sa Pharmaceutical formulation
WO1998051281A1 (fr) * 1997-05-14 1998-11-19 Senju Pharmaceutical Co., Ltd. Preparations a base de suspensions aqueuses possedant d'excellentes proprietes de redispersion
EP1039932A1 (en) * 1997-12-23 2000-10-04 Alliance Pharmaceutical Corporation Methods and compositions for the delivery of pharmaceutical agents and/or the prevention of adhesions
US6197347B1 (en) 1998-06-29 2001-03-06 Andrx Pharmaceuticals, Inc. Oral dosage for the controlled release of analgesic
ES2155027B1 (es) * 1999-05-24 2001-12-01 Univ Pais Vasco Geles para propositos multiples, reversibles y degradables.
ES2273702T3 (es) * 1999-06-11 2007-05-16 Cytyc Corporation Composicion liquido en gel para cartografiar un conducto galactoforo mamario antes de la escxision quirurgica del conducto o de otro tejido mamario.
US6576224B1 (en) * 1999-07-06 2003-06-10 Sinuspharma, Inc. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
US20020061281A1 (en) * 1999-07-06 2002-05-23 Osbakken Robert S. Aerosolized anti-infectives, anti-inflammatories, and decongestants for the treatment of sinusitis
JP2001158750A (ja) * 1999-12-02 2001-06-12 Lion Corp 眼科用組成物及び抗アレルギー薬の持続性向上方法
JP3450805B2 (ja) * 2000-08-08 2003-09-29 わかもと製薬株式会社 水性医薬組成物
US7420030B2 (en) 2000-09-08 2008-09-02 The Board Of Regents Of The University Of Texas System Aminopeptidase A (APA) targeting peptides for the treatment of cancer
AU2001291159A1 (en) * 2000-09-20 2002-04-02 Shahinian Jr., Lee Self-preserved nasal, inhalable, and topical ophthalmic preparations and medications
JP4820024B2 (ja) * 2001-01-10 2011-11-24 昭和薬品化工株式会社 局所麻酔用組成物
CA2454357A1 (en) * 2001-07-18 2003-01-30 Wadih Arap An anti-angiogenic state in mice and humans with retinal photoreceptor cell degeneration
US20040048243A1 (en) * 2001-09-07 2004-03-11 Wadih Arap Methods and compositions for in vitro targeting
US6846846B2 (en) * 2001-10-23 2005-01-25 The Trustees Of Columbia University In The City Of New York Gentle-acting skin disinfectants
US7745425B2 (en) * 2002-02-07 2010-06-29 The Trustees Of Columbia University In The City Of New York Non-irritating compositions containing zinc salts
US7879365B2 (en) * 2002-02-07 2011-02-01 The Trustees Of Columbia University In The City Of New York Zinc salt compositions for the prevention of dermal and mucosal irritation
CA2475224C (en) * 2002-02-07 2011-11-01 The Trustees Of Columbia University In The City Of New York Zinc salt compositions for the prevention of mucosal irritation from spermicides and microbicides
KR20100102749A (ko) * 2002-02-22 2010-09-24 산텐 세이야꾸 가부시키가이샤 미립자 결막하 투여를 위한 약물 수송 시스템
US20030211173A1 (en) * 2002-05-08 2003-11-13 Veach Tom C. Lubrication composition
AU2003264498A1 (en) * 2002-09-18 2004-04-08 Wakamoto Pharmaceutical Co., Ltd. Transparent and reversibly heat-gelling aqueous compositions
US7220431B2 (en) 2002-11-27 2007-05-22 Regents Of The University Of Minnesota Methods and compositions for applying pharmacologic agents to the ear
JP2004196787A (ja) * 2002-12-04 2004-07-15 Santen Pharmaceut Co Ltd 結膜下デポによるドラッグデリバリーシステム
KR20050086903A (ko) * 2002-12-10 2005-08-30 쇼와 야쿠힝 가코 가부시키가이샤 국소마취용 조성물
US20050085446A1 (en) * 2003-04-14 2005-04-21 Babu M.K. M. Fluoroquinolone formulations and methods of making and using the same
JP4669960B2 (ja) * 2003-06-03 2011-04-13 株式会社 メドレックス 局所麻酔薬を含有する口中用または咽頭部用製剤
CA2532730C (en) * 2003-07-17 2013-02-26 The Trustees Of Columbia University In The City Of New York Antimicrobial compositions containing synergistic combinations of quaternary ammonium compounds and essential oils and/or constituents thereof
TWI347847B (en) * 2003-08-20 2011-09-01 Santen Pharmaceutical Co Ltd Drug delivery system for sub-tenon administration of fine particles
FR2860718B1 (fr) * 2003-10-09 2006-02-24 Jean Pascal Conduzorgues Nouvelle formulation et ses applications dans le domaines cosmetiques ou pharmaceutiques
US20070110689A1 (en) * 2004-01-15 2007-05-17 Mark Feldschuh Oral anaesthetic gel
US7658947B2 (en) 2004-06-25 2010-02-09 Kimberly-Clark Worldwide, Inc. Thermo-gelling composition
JP2007277095A (ja) * 2004-07-02 2007-10-25 Wakamoto Pharmaceut Co Ltd アジスロマイシン含有可逆性熱ゲル化水性組成物
US7459416B2 (en) * 2004-07-12 2008-12-02 Panasonic Corporation Fluid bearing unit and spindle motor using the same
EP1858482B1 (en) 2005-03-10 2014-04-23 3M Innovative Properties Company Methods of reducing microbial contamination
JP4979258B2 (ja) * 2005-04-08 2012-07-18 ロート製薬株式会社 アシタザノラスト含有水性組成物
CN100463668C (zh) * 2005-05-09 2009-02-25 凌沛学 可逆性热凝胶化水性药物组合物
CN100430069C (zh) * 2005-07-28 2008-11-05 凌沛学 一种中药及其复方的可逆性热凝胶化水性药物组合物
DE602006012865D1 (de) * 2005-10-17 2010-04-22 Kowa Co Indometacin enthaltende flüssige zubereitung zur externen anwendung
EA008737B1 (ru) * 2005-12-07 2007-08-31 Леонид Андреевич Кожемякин Средство для профилактики и лечения конъюнктивитов и кератитов различной этиологии (варианты), способ его применения
US7759327B2 (en) 2006-01-06 2010-07-20 The Trustees Of Columbia University In The City Of New York Compositions containing zinc salts for coating medical articles
US20070249546A1 (en) * 2006-04-22 2007-10-25 Sawaya Assad S Ophthalmic and related aqueous solutions containing antifungal agents, uses therefor and methods for preparing them
US20070254854A1 (en) * 2006-05-01 2007-11-01 Medi-Flex, Inc. Aqueous Antiseptic Solution and Compatible Anionic Dye for Staining Skin
US20080108674A1 (en) * 2006-05-01 2008-05-08 Enturia, Inc. Cationic antiseptic and dye formulation
US20070253909A1 (en) * 2006-05-01 2007-11-01 Medi-Flex, Inc. Aqueous Antiseptic Solution and Compatible Cationic Dye for Staining Skin
TW200808375A (en) * 2006-05-12 2008-02-16 Otsuka Pharma Co Ltd Hydrogel suspension and manufacturing process thereof
EA014780B1 (ru) * 2007-01-05 2011-02-28 Промед Экспортс Пвт. Лтд. Офтальмическая композиция
DE102007002073A1 (de) * 2007-01-09 2008-07-10 Matthias Habenicht Mittel zur Pflege und antimikrobiellen Behandlung der Haut
JP5340149B2 (ja) * 2007-06-26 2013-11-13 わかもと製薬株式会社 水性組成物
WO2009028674A1 (ja) * 2007-08-29 2009-03-05 Wakamoto Pharmaceutical Co., Ltd. ラタノプロスト含有水性医薬組成物
WO2009074853A2 (en) * 2007-12-10 2009-06-18 Promed Research Centre Ophthalmic composition comprising phenylephrine
CA2723458C (en) * 2008-05-14 2014-01-28 Otonomy, Inc. Controlled release corticosteroid compositions and methods for the treatment of otic disorders
US10517839B2 (en) * 2008-06-09 2019-12-31 Cornell University Mast cell inhibition in diseases of the retina and vitreous
TW201023912A (en) * 2008-12-05 2010-07-01 Alcon Res Ltd Pharmaceutical suspension
CN105362221A (zh) * 2009-03-03 2016-03-02 爱尔康研究有限公司 向眼部递送受体酪氨酸激酶抑制性(RTKi)化合物的药物组合物
US8912236B2 (en) * 2009-03-03 2014-12-16 Alcon Research, Ltd. Pharmaceutical composition for delivery of receptor tyrosine kinase inhibiting (RTKi) compounds to the eye
MX2011008731A (es) * 2009-03-03 2011-09-29 Alcon Res Ltd Composicion farmaceutica para el suministro de compuestos inhibidores de la tirosina cinasa receptora (rtki) para los ojos.
US8299079B2 (en) 2009-05-22 2012-10-30 Kaufman Herbert E Preparations and methods for ameliorating or reducing presbyopia
US20100298335A1 (en) * 2009-05-22 2010-11-25 Kaufman Herbert E Preparations and Methods for Ameliorating or Reducing Presbyopia
US20130149394A1 (en) 2010-08-27 2013-06-13 Wakamoto Pharmaceutical Co., Ltd. Aqueous ophthalmic composition
TWI544922B (zh) 2011-05-19 2016-08-11 愛爾康研究有限公司 高濃度歐羅派特錠(olopatadine)眼用組成物
WO2013169458A1 (en) * 2012-05-11 2013-11-14 Bausch & Lomb Incorporated Pharmaceutical compositions and methods for treating, controlling, ameliorating, or reversing conditions of dry eye
RU2485939C1 (ru) * 2012-06-19 2013-06-27 Станислав Анатольевич Кедик Офтальмологический препарат в виде глазных капель, содержащий дисульфирам и таурин
US10507245B2 (en) * 2012-07-19 2019-12-17 Luis Felipe Vejarano Restrepo Ophthalmic formulation and method for ameliorating presbyopia
RU2517033C1 (ru) * 2013-03-05 2014-05-27 федеральное государственное бюджетное учреждение "Межотраслевой научно-технический комплекс "Микрохирургия глаза" имени академика С.Н. Федорова" Министерства здравоохранения Российской Федерации Композиция для комплексного лечения больных с первичной открытоугольной глаукомой и заболеваниями глазной поверхности
CN103239390B (zh) * 2013-05-15 2014-08-06 中国人民解放军第三军医大学第二附属医院 托吡卡胺眼用温度敏感原位凝胶及其制备方法
EP3082868A1 (en) * 2013-12-20 2016-10-26 The Procter & Gamble Company Stable liquid medication containing diphenhydramine
JP6714247B2 (ja) * 2017-10-06 2020-06-24 有限会社ジーエヌコーポレーション 尿道狭窄治療剤および尿道狭窄治療方法
WO2019230750A1 (ja) * 2018-05-29 2019-12-05 学校法人 神野学園 外用組成物
WO2020112655A1 (en) * 2018-11-26 2020-06-04 Aiviva Biopharma, Inc. Pharmaceutical biodissolvable gels for drug delivery

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3311577A (en) * 1965-03-29 1967-03-28 Burton Parsons Chemicals Inc Underwater contact lens solution
US4100271A (en) * 1976-02-26 1978-07-11 Cooper Laboratories, Inc. Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
US4188373A (en) * 1976-02-26 1980-02-12 Cooper Laboratories, Inc. Clear, water-miscible, liquid pharmaceutical vehicles and compositions which gel at body temperature for drug delivery to mucous membranes
DE2714065A1 (de) * 1977-03-30 1978-10-12 Boehringer Mannheim Gmbh Instillationszubereitung
US4478822A (en) * 1983-05-16 1984-10-23 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels
US4474752A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Drug delivery system utilizing thermosetting gels
US4474753A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Topical drug delivery system utilizing thermosetting gels
US4474751A (en) * 1983-05-16 1984-10-02 Merck & Co., Inc. Ophthalmic drug delivery system utilizing thermosetting gels
FR2588189B1 (fr) * 1985-10-03 1988-12-02 Merck Sharp & Dohme Composition pharmaceutique de type a transition de phase liquide-gel
GB2203039B (en) * 1987-03-02 1990-10-24 American Cyanamid Co Stable ophthalmic preparations containing acetazolamide
US5252318A (en) * 1990-06-15 1993-10-12 Allergan, Inc. Reversible gelation compositions and methods of use
US5077033A (en) * 1990-08-07 1991-12-31 Mediventures Inc. Ophthalmic drug delivery with thermo-irreversible gels of polxoxyalkylene polymer and ionic polysaccharide
MX9200339A (es) * 1991-01-28 1992-08-01 Hoechst Ag Preparado para la liberacion controlada de sustancias activas, que son apropiadas como terapeuticos o para mejorar el crecimiento y el aprovechamiento de los piensos en rumiantes
AU679937B2 (en) * 1992-11-18 1997-07-17 Johnson & Johnson Consumer Products, Inc. Extrudable compositions for topical or transdermal drug delivery

Also Published As

Publication number Publication date
FI953575A0 (sv) 1995-07-26
KR960700075A (ko) 1996-01-19
NO953189D0 (no) 1995-08-14
HU220864B1 (en) 2002-06-29
FI953575A (sv) 1995-07-26
DK0694310T3 (da) 2000-06-05
HK1017805A1 (en) 1999-11-26
CN1097593A (zh) 1995-01-25
CA2153234A1 (en) 1994-10-27
AU668447B2 (en) 1996-05-02
CA2153234C (en) 1999-02-16
RU2108112C1 (ru) 1998-04-10
NO953189L (no) 1995-08-14
IL107626A0 (en) 1994-02-27
DE69327878D1 (de) 2000-03-23
AU5433394A (en) 1994-11-08
HUT71676A (en) 1996-01-29
ES2141775T3 (es) 2000-04-01
US5624962A (en) 1997-04-29
EP0694310A4 (en) 1996-04-24
CN1048393C (zh) 2000-01-19
EP0694310A1 (en) 1996-01-31
HU9502086D0 (en) 1995-09-28
WO1994023750A1 (en) 1994-10-27
ATE189772T1 (de) 2000-03-15
DE69327878T2 (de) 2000-06-15
EP0694310B1 (en) 2000-02-16
NO311635B1 (no) 2001-12-27
KR0162025B1 (ko) 1998-12-01
FI112778B (sv) 2004-01-15

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