IL104740A - Hypolipidaemic benzothiazepine compounds their preparation and pharmaceutical compositions containing them - Google Patents

Hypolipidaemic benzothiazepine compounds their preparation and pharmaceutical compositions containing them

Info

Publication number
IL104740A
IL104740A IL10474093A IL10474093A IL104740A IL 104740 A IL104740 A IL 104740A IL 10474093 A IL10474093 A IL 10474093A IL 10474093 A IL10474093 A IL 10474093A IL 104740 A IL104740 A IL 104740A
Authority
IL
Israel
Prior art keywords
compound
formula
ethyl
solvate
butyl
Prior art date
Application number
IL10474093A
Other languages
English (en)
Other versions
IL104740A0 (en
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of IL104740A0 publication Critical patent/IL104740A0/xx
Publication of IL104740A publication Critical patent/IL104740A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
IL10474093A 1992-02-17 1993-02-16 Hypolipidaemic benzothiazepine compounds their preparation and pharmaceutical compositions containing them IL104740A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929203347A GB9203347D0 (en) 1992-02-17 1992-02-17 Hypolipidaemic compounds

Publications (2)

Publication Number Publication Date
IL104740A0 IL104740A0 (en) 1993-06-10
IL104740A true IL104740A (en) 1996-09-12

Family

ID=10710542

Family Applications (1)

Application Number Title Priority Date Filing Date
IL10474093A IL104740A (en) 1992-02-17 1993-02-16 Hypolipidaemic benzothiazepine compounds their preparation and pharmaceutical compositions containing them

Country Status (21)

Country Link
US (2) US5663165A (OSRAM)
EP (1) EP0626952B1 (OSRAM)
JP (1) JP2904926B2 (OSRAM)
KR (1) KR100265529B1 (OSRAM)
AT (1) ATE178897T1 (OSRAM)
AU (1) AU675419B2 (OSRAM)
CA (1) CA2117485A1 (OSRAM)
DE (1) DE69324479T2 (OSRAM)
DK (1) DK0626952T3 (OSRAM)
ES (1) ES2131106T3 (OSRAM)
FI (1) FI943775A0 (OSRAM)
GB (1) GB9203347D0 (OSRAM)
GR (1) GR3030491T3 (OSRAM)
HU (1) HUT71487A (OSRAM)
IL (1) IL104740A (OSRAM)
MX (1) MX9300821A (OSRAM)
MY (1) MY129970A (OSRAM)
NZ (1) NZ249189A (OSRAM)
TW (1) TW274547B (OSRAM)
WO (1) WO1993016055A1 (OSRAM)
ZA (1) ZA931073B (OSRAM)

Families Citing this family (126)

* Cited by examiner, † Cited by third party
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JP2025539895A (ja) 2022-12-09 2025-12-09 アルビレオ・アクチボラグ 腎臓の疾患の治療におけるａｓｂｔ阻害剤
WO2025146507A1 (en) 2024-01-05 2025-07-10 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators
WO2025146508A1 (en) 2024-01-05 2025-07-10 Albireo Ab Benzothia(di)azepine compounds and their use as bile acid modulators

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US3362962A (en) * 1964-01-24 1968-01-09 Hoffmann La Roche Certain benzothiazepine derivatives
US5276025A (en) * 1992-09-09 1994-01-04 Merck & Co., Inc. Heterobicyclic sulfonamides

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DE69324479D1 (de) 1999-05-20
US5859240A (en) 1999-01-12
US5663165A (en) 1997-09-02
EP0626952A1 (en) 1994-12-07
HUT71487A (en) 1995-11-28
HU9402365D0 (en) 1994-10-28
KR950700265A (ko) 1995-01-16
DK0626952T3 (da) 1999-10-25
AU675419B2 (en) 1997-02-06
ATE178897T1 (de) 1999-04-15
WO1993016055A1 (en) 1993-08-19
HK1004217A1 (en) 1998-11-20
AU3508293A (en) 1993-09-03
MX9300821A (es) 1993-09-01
FI943775L (fi) 1994-08-16
TW274547B (OSRAM) 1996-04-21
KR100265529B1 (ko) 2000-11-01
IL104740A0 (en) 1993-06-10
JPH07503724A (ja) 1995-04-20
GB9203347D0 (en) 1992-04-01
ES2131106T3 (es) 1999-07-16
MY129970A (en) 2007-05-31
FI943775A7 (fi) 1994-08-16
NZ249189A (en) 1996-02-27
FI943775A0 (fi) 1994-08-16
JP2904926B2 (ja) 1999-06-14
EP0626952B1 (en) 1999-04-14
DE69324479T2 (de) 1999-09-16
GR3030491T3 (en) 1999-10-29
CA2117485A1 (en) 1993-08-19
ZA931073B (en) 1994-08-16

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