IL103054A - Method for identifying light absorbing subclasses of cells in whole blood - Google Patents

Method for identifying light absorbing subclasses of cells in whole blood

Info

Publication number
IL103054A
IL103054A IL103054A IL10305492A IL103054A IL 103054 A IL103054 A IL 103054A IL 103054 A IL103054 A IL 103054A IL 10305492 A IL10305492 A IL 10305492A IL 103054 A IL103054 A IL 103054A
Authority
IL
Israel
Prior art keywords
cells
subclasses
light
whole blood
light absorbing
Prior art date
Application number
IL103054A
Other languages
English (en)
Other versions
IL103054A0 (en
Original Assignee
Bayer Corp Ny
Sinai School Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Corp Ny, Sinai School Medicine filed Critical Bayer Corp Ny
Publication of IL103054A0 publication Critical patent/IL103054A0/xx
Publication of IL103054A publication Critical patent/IL103054A/xx

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/80Fluorescent dyes, e.g. rhodamine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/10Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497Preparation composition [e.g., lysing or precipitation, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Ecology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
IL103054A 1991-12-05 1992-09-04 Method for identifying light absorbing subclasses of cells in whole blood IL103054A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/802,593 US5350695A (en) 1991-12-05 1991-12-05 Methods for the identification and characterization of reticulocytes in whole blood

Publications (2)

Publication Number Publication Date
IL103054A0 IL103054A0 (en) 1993-02-21
IL103054A true IL103054A (en) 1997-07-13

Family

ID=25184159

Family Applications (1)

Application Number Title Priority Date Filing Date
IL103054A IL103054A (en) 1991-12-05 1992-09-04 Method for identifying light absorbing subclasses of cells in whole blood

Country Status (12)

Country Link
US (2) US5350695A (xx)
EP (1) EP0545314B1 (xx)
JP (1) JP2802710B2 (xx)
KR (1) KR100276144B1 (xx)
AT (1) ATE161952T1 (xx)
AU (1) AU2816592A (xx)
CA (1) CA2077788C (xx)
DE (1) DE69223930T2 (xx)
DK (1) DK0545314T3 (xx)
ES (1) ES2111599T3 (xx)
IL (1) IL103054A (xx)
TW (1) TW287232B (xx)

Families Citing this family (50)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0698211B1 (en) * 1993-05-14 2003-04-02 Coulter International Corporation Reticulocyte analyzing method and apparatus utilizing light scatter techniques
US5563070A (en) * 1993-05-28 1996-10-08 Omron Corporation Method of counting reticulocytes
JP3320869B2 (ja) * 1993-12-22 2002-09-03 シスメックス株式会社 白血球分析用試薬
ES2156927T3 (es) * 1994-10-20 2001-08-01 Sysmex Corp Reactivo y metodo para analizar componentes solidos en orina.
US5691204A (en) * 1995-04-21 1997-11-25 Abbott Laboratories Compositions and methods for the rapid analysis of reticulocytes
DE19521231A1 (de) * 1995-06-10 1996-12-12 Boehringer Mannheim Gmbh Neue Oxazinfarbstoffe und ihre Verwendung als Fluoreszenzmarker
US5733784A (en) * 1995-11-20 1998-03-31 Abbott Laboratories Reagent system and method for the differentiation and identification of reticulocytes
US5817519A (en) * 1995-12-28 1998-10-06 Bayer Corporation Automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
US6025201A (en) * 1995-12-28 2000-02-15 Bayer Corporation Highly sensitive, accurate, and precise automated method and device for identifying and quantifying platelets and for determining platelet activation state using whole blood samples
TW379284B (en) * 1996-04-12 2000-01-11 Toa Medical Electronics Agent for detecting reticulocyte
FR2759166B1 (fr) * 1997-01-31 1999-04-23 Abx Sa Reactif de coloration pour la determination de cellules sanguines
US6114173A (en) * 1997-04-03 2000-09-05 Bayer Corporation Fully automated method and reagent composition therefor for rapid identification and characterization of reticulocytes erythrocytes and platelets in whole blood
JP3350442B2 (ja) * 1998-04-09 2002-11-25 科学技術振興事業団 顕微鏡システム
US6060322A (en) * 1998-10-20 2000-05-09 Coulter International Corp. Method for identification of reticulated cells
US6271035B1 (en) 1998-10-20 2001-08-07 Coulter International Corp. Methods and compositions for rapid staining of nucleic acids in whole cells
JP3886271B2 (ja) * 1998-11-27 2007-02-28 シスメックス株式会社 赤芽球の分類計数用試薬及び分類計数方法
EP1166110A1 (en) * 1999-03-31 2002-01-02 Bayer Corporation Single channel, single dilution detection method
US6784981B1 (en) 2000-06-02 2004-08-31 Idexx Laboratories, Inc. Flow cytometry-based hematology system
KR100381725B1 (ko) * 2000-12-29 2003-04-26 (학)가톨릭학원가톨릭중앙의료원 용혈성 빈혈 검사 방법
US6630990B2 (en) 2001-06-05 2003-10-07 Abbott Laboratories Optical method and apparatus for red blood cell differentiation on a cell-by-cell basis, and simultaneous analysis of white blood cell differentiation
DE10212960A1 (de) * 2002-03-22 2003-10-23 Gnothis Holding Sa Ecublens Verwendung von Oxazin-Farbstoffen als Markierungsgruppen für die Einzelmolekülanalyse
CA2428740A1 (en) 2002-05-20 2003-11-20 Bayer Corporation Automated method and reagent therefor for assaying body fluid samples such as cerebrospinal fluid (csf)
JP4417143B2 (ja) * 2004-03-11 2010-02-17 シスメックス株式会社 試料分析装置、プログラムおよびそのプログラムを記録した記録媒体
US7625712B2 (en) 2004-05-21 2009-12-01 Beckman Coulter, Inc. Method for a fully automated monoclonal antibody-based extended differential
US7674598B2 (en) * 2004-05-21 2010-03-09 Beckman Coulter, Inc. Method for a fully automated monoclonal antibody-based extended differential
US7110192B2 (en) * 2005-01-12 2006-09-19 Dako Denmark A/S System and method for a composite lens for a flow cytometer
US9345745B2 (en) 2005-04-29 2016-05-24 Bo Wang Methods for treating inflammatory disorders and traumatic brain injury using stabilized non-hematopoietic EPO short peptides
US8653028B2 (en) 2005-04-29 2014-02-18 Rui Rong Yuan Erythropoietin-derived short peptide and its mimics as immuno/inflammatory modulators
CN101252994B (zh) * 2005-07-01 2011-04-13 霍尼韦尔国际公司 用于红血细胞分析的微流体卡
US7804594B2 (en) 2006-12-29 2010-09-28 Abbott Laboratories, Inc. Method and apparatus for rapidly counting and identifying biological particles in a flow stream
US7728974B2 (en) * 2007-02-07 2010-06-01 Cytopeia, Inc. Enhanced detection system and method
CN101349644B (zh) * 2007-07-20 2012-06-27 深圳迈瑞生物医疗电子股份有限公司 一种白细胞分类试剂和其使用方法
US8102161B2 (en) * 2007-09-25 2012-01-24 Tdk Corporation Stable output in a switching power supply by smoothing the output of the secondary coil
EP2215219A4 (en) * 2007-10-29 2011-04-13 Beckman Coulter Inc METHOD FOR RAPID ANALYSIS BASED ON ANTIBODIES OF POPULATIONS OF PLATELETS
US8159670B2 (en) * 2007-11-05 2012-04-17 Abbott Laboratories Method and apparatus for rapidly counting and identifying biological particles in a flow stream
CN101475754A (zh) * 2008-01-04 2009-07-08 深圳迈瑞生物医疗电子股份有限公司 不对称菁类荧光染料,组合物及在生物样品染色中的用途
CN101602762B (zh) * 2008-06-10 2013-10-16 深圳迈瑞生物医疗电子股份有限公司 不对称菁类化合物、其制备方法及应用
CN101726579B (zh) * 2008-10-17 2014-06-18 深圳迈瑞生物医疗电子股份有限公司 血液检测试剂和方法
CN101750274B (zh) * 2008-12-17 2014-06-25 深圳迈瑞生物医疗电子股份有限公司 白细胞分类计数试剂、试剂盒以及白细胞分类计数的方法
WO2010085632A2 (en) 2009-01-23 2010-07-29 University Of Washington Virtual core flow cytometry
JP4969596B2 (ja) * 2009-02-04 2012-07-04 シスメックス株式会社 試料分析装置、試料分析方法およびプログラム
JP5871792B2 (ja) 2009-04-27 2016-03-01 アボット・ラボラトリーズAbbott Laboratories 自動血液分析器において、レーザーからの前方散乱を用いることによる、赤血球細胞を白血球細胞から判別する方法
CN101988082B (zh) * 2009-07-31 2015-04-08 深圳迈瑞生物医疗电子股份有限公司 白细胞分类计数试剂、试剂盒及其制备方法和白细胞分类计数的方法
US8906308B2 (en) 2010-01-15 2014-12-09 Abbott Laboratories Method for determining volume and hemoglobin content of individual red blood cells
US9097704B2 (en) 2010-05-05 2015-08-04 Abbott Laboratories Method for hematology analysis
US10107746B2 (en) 2015-01-08 2018-10-23 University Of Washington System and method for immersion flow cytometry
WO2017106439A1 (en) * 2015-12-18 2017-06-22 Abbott Laboratories Particle detection methods and systems for practicing same
US10509024B2 (en) 2016-05-04 2019-12-17 LabThroughput LLC System and method for distinguishing blood components
AU2019242902B2 (en) 2018-03-30 2021-10-28 Idexx Laboratories, Inc. Laser optics assembly of flow cytometer
EP4168773A1 (en) 2020-06-17 2023-04-26 Idexx Laboratories, Inc. Flow cytometer and laser optics assembly thereof

Family Cites Families (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3684377A (en) * 1970-07-13 1972-08-15 Bio Physics Systems Inc Method for analysis of blood by optical analysis of living cells
US3883247A (en) * 1973-10-30 1975-05-13 Bio Physics Systems Inc Method for fluorescence analysis of white blood cells
US4346018A (en) * 1980-06-16 1982-08-24 Coulter Electronics, Inc. Multi-purpose blood diluent and lysing agent for differential determination of lymphoid-myeloid population of leukocytes
US4325706A (en) * 1980-08-15 1982-04-20 Ortho Diagnostic Systems Inc. Automated detection of platelets and reticulocytes in whole blood
US4336029A (en) * 1980-08-15 1982-06-22 Ortho Diagnostic Systems Inc. Method and reagents for quantitative determination of reticulocytes and platelets in whole blood
US4412004A (en) * 1981-06-26 1983-10-25 Technicon Instruments Corporation Method for treating red blood cells to effect sphering and reagent therefor
IT1140209B (it) * 1981-09-25 1986-09-24 Anic Spa Reagenti per immunoluorescenza e metodo per la loro preparazione
US4571388A (en) * 1983-01-24 1986-02-18 Becton Dickinson And Company Detection of reticulocytes
US4490353A (en) * 1983-07-13 1984-12-25 Colgate-Palmolive Company Antiplaque dentifrice with improved fluoride stability
US4735504A (en) * 1983-10-31 1988-04-05 Technicon Instruments Corporation Method and apparatus for determining the volume & index of refraction of particles
US4575490A (en) * 1984-02-29 1986-03-11 Technicon Instruments Corporation One step method for sphering and fixing whole blood erythrocytes
JPS61502280A (ja) * 1984-05-31 1986-10-09 ク−ルタ−・エレクトロニクス・インコ−ポレ−テッド 白血球のクラスおよびサブクラスの同定、計数並びに試験方法およびそれに用いる試薬系
US4652517A (en) * 1984-06-11 1987-03-24 Diagnostic Research Limited Partnership Methods for the in vitro detection and identification of unknown pathogens or genetic entities
JPS6179163A (ja) * 1984-09-26 1986-04-22 Toa Medical Electronics Co Ltd 血球測定用試薬
JPS61280565A (ja) * 1985-06-06 1986-12-11 Toa Medical Electronics Co Ltd フロ−サイトメトリ−用網状血球測定試薬
US4745071A (en) * 1985-09-05 1988-05-17 Sequoia-Turner Corporation Method for the volumetric differentiation of blood cells types
US4978624A (en) * 1985-09-06 1990-12-18 Technicon Instruments Corporation Reagent for the determination of a differential white blood cell count
US4707451A (en) * 1985-09-18 1987-11-17 Becton, Dickinson And Company Detection of reticulocytes
DE3677916D1 (de) * 1985-11-01 1991-04-11 Becton Dickinson Co Nachweis von retikulozyten.
US4883867A (en) * 1985-11-01 1989-11-28 Becton, Dickinson And Company Detection of reticulocytes, RNA or DNA
US5039613A (en) * 1986-11-27 1991-08-13 Toa Medical Electronics Co., Ltd. Reagents used in a method of classifying leukocytes by flow cytometry
JPH0746102B2 (ja) * 1987-07-31 1995-05-17 東亜医用電子株式会社 フロ−サイトメトリ用網状赤血球測定試薬
JP2549665B2 (ja) * 1987-07-31 1996-10-30 東亜医用電子株式会社 フロ−サイトメトリ用網状赤血球測定試薬
IT8921788A0 (it) * 1989-09-21 1989-09-21 Diesse Diagnostica Reattivo utile per la rilevazione e la determinazione quantitativa dei leucociti in fluidi biologici.
JPH0782013B2 (ja) * 1989-10-27 1995-09-06 三菱化学株式会社 網状赤血球計数装置
US5075556A (en) * 1989-12-01 1991-12-24 Technicon Instruments Corporation Acridine orange derivatives and their use in the quantitation of reticulocytes in whole blood

Also Published As

Publication number Publication date
EP0545314B1 (en) 1998-01-07
EP0545314A1 (en) 1993-06-09
DK0545314T3 (da) 1998-09-07
AU2816592A (en) 1993-06-10
DE69223930D1 (de) 1998-02-12
US5438003A (en) 1995-08-01
IL103054A0 (en) 1993-02-21
CA2077788C (en) 1998-07-14
TW287232B (xx) 1996-10-01
ATE161952T1 (de) 1998-01-15
ES2111599T3 (es) 1998-03-16
KR100276144B1 (ko) 2000-12-15
CA2077788A1 (en) 1993-06-06
JPH06180314A (ja) 1994-06-28
JP2802710B2 (ja) 1998-09-24
US5350695A (en) 1994-09-27
DE69223930T2 (de) 1998-04-30

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