ES2111599T3 - Composiciones reactivas y su uso para identificar y caracterizar reticulocitos en sangre completa. - Google Patents

Composiciones reactivas y su uso para identificar y caracterizar reticulocitos en sangre completa.

Info

Publication number
ES2111599T3
ES2111599T3 ES92120308T ES92120308T ES2111599T3 ES 2111599 T3 ES2111599 T3 ES 2111599T3 ES 92120308 T ES92120308 T ES 92120308T ES 92120308 T ES92120308 T ES 92120308T ES 2111599 T3 ES2111599 T3 ES 2111599T3
Authority
ES
Spain
Prior art keywords
reticulocytes
cell
erythrocytes
measured
hemoglobin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92120308T
Other languages
English (en)
Inventor
Gregory M Colella
Daniel Ben-David
Albert Cupo
Sophie S Fan
Gena Fischer
Grace E Martin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Corp
Icahn School of Medicine at Mount Sinai
Original Assignee
Bayer AG
Bayer Corp
Mount Sinai School of Medicine
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG, Bayer Corp, Mount Sinai School of Medicine filed Critical Bayer AG
Application granted granted Critical
Publication of ES2111599T3 publication Critical patent/ES2111599T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/80—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood groups or blood types or red blood cells
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5094—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for blood cell populations
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/80—Fluorescent dyes, e.g. rhodamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/101666—Particle count or volume standard or control [e.g., platelet count standards, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Ecology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

METODOS PARA CARACTERIZAR E IDENTIFICAR RETICULOCITOS Y HEMATIES UTILIZAN COMPOSICIONES REACTIVAS QUE INCLUYEN TINTES CATIONICOS ORGANICOS PARA TEÑIR LOS RETICULOCITOS DE LAS MUESTRAS SANGUINEAS Y SOLUCIONES AMORTIGUADORAS PARA MANTENER UN PH ENTRE 6 A 9. LOS TINTES PUEDEN SER LOS TINTES DE ABSORCION DE AZUL OXAZINA 750 O NUEVO AZUL DE METILENO. CUANDO UN SUPERFICIACTIVO ZWITERONICO SE INCLUYE EN LA COMPOSICION REACTIVA PARA HACER ESFERICOS ISOVOLUMETRICAMENTE LOS RETICULOCITOS Y ERITROCITOS, Y LA COMPOSICION REACTIVA Y TODA LA MUESTRA DE SANGRE SE PASA POR LA REGION SENSIBLE DE UN CITOMETRO DE FLUJO, SE MIDE LA LUZ ESPARCIDA Y ABSORBIDA POR CADA CELULA; LOS ERITROCITOS PUEDEN DISTINGUIRSE DE LOS RETICULOCITOS, Y EL VOLUMEN Y CONCENTRACION DE HEMOGLOBINA Y EL CONTENIDO DE HEMOGLOBINA DE CADA RETICULOCITO Y ERITROCITO, Y EL VOLUMEN CELULAR MEDIO, CONCENTRACION DE HEMOGLOBINA CORPUSCULAR MEDIA Y HEMOGLOBINA CELULAR MEDIA DE LOS RETICULOCITOS Y ERITROCITOS SE CALCULA DEL VOLUMEN CELULA POR CELULA MEDIDO Y CONCENTRACION DE HEMOGLOBINA. EL METODO INCLUYE ASIMISMO AJUSTAR LAS SEÑALES DE ABSORCION PARA SEUDO-ABSORCION.
ES92120308T 1991-12-05 1992-11-27 Composiciones reactivas y su uso para identificar y caracterizar reticulocitos en sangre completa. Expired - Lifetime ES2111599T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/802,593 US5350695A (en) 1991-12-05 1991-12-05 Methods for the identification and characterization of reticulocytes in whole blood

Publications (1)

Publication Number Publication Date
ES2111599T3 true ES2111599T3 (es) 1998-03-16

Family

ID=25184159

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92120308T Expired - Lifetime ES2111599T3 (es) 1991-12-05 1992-11-27 Composiciones reactivas y su uso para identificar y caracterizar reticulocitos en sangre completa.

Country Status (12)

Country Link
US (2) US5350695A (es)
EP (1) EP0545314B1 (es)
JP (1) JP2802710B2 (es)
KR (1) KR100276144B1 (es)
AT (1) ATE161952T1 (es)
AU (1) AU2816592A (es)
CA (1) CA2077788C (es)
DE (1) DE69223930T2 (es)
DK (1) DK0545314T3 (es)
ES (1) ES2111599T3 (es)
IL (1) IL103054A (es)
TW (1) TW287232B (es)

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Also Published As

Publication number Publication date
EP0545314B1 (en) 1998-01-07
EP0545314A1 (en) 1993-06-09
DK0545314T3 (da) 1998-09-07
AU2816592A (en) 1993-06-10
DE69223930D1 (de) 1998-02-12
US5438003A (en) 1995-08-01
IL103054A0 (en) 1993-02-21
CA2077788C (en) 1998-07-14
IL103054A (en) 1997-07-13
TW287232B (es) 1996-10-01
ATE161952T1 (de) 1998-01-15
KR100276144B1 (ko) 2000-12-15
CA2077788A1 (en) 1993-06-06
JPH06180314A (ja) 1994-06-28
JP2802710B2 (ja) 1998-09-24
US5350695A (en) 1994-09-27
DE69223930T2 (de) 1998-04-30

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