ES2067598T3 - Reactivo util para la deteccion y determinacion cuantitativa de leucocitos en fluidos biologicos y metodo para su uso. - Google Patents

Reactivo util para la deteccion y determinacion cuantitativa de leucocitos en fluidos biologicos y metodo para su uso.

Info

Publication number
ES2067598T3
ES2067598T3 ES90113305T ES90113305T ES2067598T3 ES 2067598 T3 ES2067598 T3 ES 2067598T3 ES 90113305 T ES90113305 T ES 90113305T ES 90113305 T ES90113305 T ES 90113305T ES 2067598 T3 ES2067598 T3 ES 2067598T3
Authority
ES
Spain
Prior art keywords
leukocytes
detection
biological fluids
quantitative determination
useful reagent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90113305T
Other languages
English (en)
Inventor
Franco Meiattini
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diesse Diagnostica Senese SRL
Original Assignee
Diesse Diagnostica Senese SRL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Diesse Diagnostica Senese SRL filed Critical Diesse Diagnostica Senese SRL
Application granted granted Critical
Publication of ES2067598T3 publication Critical patent/ES2067598T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00—Chemistry: analytical and immunological testing
    • Y10S436/904—Oxidation - reduction indicators
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/107497—Preparation composition [e.g., lysing or precipitation, etc.]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/10—Composition for standardization, calibration, simulation, stabilization, preparation or preservation; processes of use in preparation for chemical testing
    • Y10T436/108331—Preservative, buffer, anticoagulant or diluent

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

EL INVENTO ES CON RELACION A UN REACTIVO DETERMINANTE PARA DETECTAR Y CUANTIFICAR LOS LEUCOCITOS PARA MEDIR LA MIELOPERIDASE (MPO) MUESTRA LA ACTIVIDAD BIOLOGICA, QUE ES BASTANTE SENSIBLE PARA REVELAR SOLO EL NIVEL DE LEUCOCITO, SIN INTERFERENCIAS CAUSADAS POR EL NIVEL DE LA HEMOGLOBINA EN LA PRESENCIA DE VARIOS ERITOCITOS, Y ES CONVENIENTE PARA LA LECTURA FOTOMETRICA EL VISIBLE ASPECTO DE LA REGION. EL REACTIVO COMPRENDE UN AMORTIGUADOR, UN CROMOGEN, UN AGENTE ACTIVO TRANSPORTADO, Y AL MENOS UN METAL ALCALINO HALIDO, Y UN COMPUESTO OPCIONAL PROMOVIDO A REACCION. EL INVENTO TAMBIEN RELATA UN METODO REACTIVO USADO PARA DIVIDIR EN DOS COMPONENTES
ES90113305T 1989-09-21 1990-07-12 Reactivo util para la deteccion y determinacion cuantitativa de leucocitos en fluidos biologicos y metodo para su uso. Expired - Lifetime ES2067598T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8921788A IT8921788A0 (it) 1989-09-21 1989-09-21 Reattivo utile per la rilevazione e la determinazione quantitativa dei leucociti in fluidi biologici.

Publications (1)

Publication Number Publication Date
ES2067598T3 true ES2067598T3 (es) 1995-04-01

Family

ID=11186861

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90113305T Expired - Lifetime ES2067598T3 (es) 1989-09-21 1990-07-12 Reactivo util para la deteccion y determinacion cuantitativa de leucocitos en fluidos biologicos y metodo para su uso.

Country Status (7)

Country Link
US (1) US5128265A (es)
EP (1) EP0418486B1 (es)
AT (1) ATE113663T1 (es)
DE (1) DE69013834T2 (es)
DK (1) DK0418486T3 (es)
ES (1) ES2067598T3 (es)
IT (1) IT8921788A0 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6046019A (en) * 1991-07-09 2000-04-04 Goumeniouk; Alexander P. Diagnostic kits and methods for making granulocyte cell counts
US5360739A (en) * 1991-12-05 1994-11-01 Miles Inc. Methods for the identification and characterization of reticulocytes in whole blood
US5350695A (en) * 1991-12-05 1994-09-27 Miles Inc. Methods for the identification and characterization of reticulocytes in whole blood
US5776780A (en) * 1993-05-28 1998-07-07 Chimera Research & Chemical, Inc. Method for quantitatively measuring white blood cells esterase activity in urine
US5516700A (en) * 1993-05-28 1996-05-14 Chimera Research And Chemical, Inc. Automated urinalysis method
JP3324050B2 (ja) * 1994-10-31 2002-09-17 日本光電工業株式会社 白血球分類用試薬および白血球分類方法
US5639630A (en) * 1995-05-16 1997-06-17 Bayer Corporation Method and reagent composition for performing leukocyte differential counts on fresh and aged whole blood samples, based on intrinsic peroxidase activity of leukocytes
US7780950B2 (en) 2002-01-02 2010-08-24 The Cleveland Clinic Foundation Systemic marker for monitoring anti-inflammatory and antioxidant actions of therapeutic agents
DK1353666T3 (da) 2001-01-02 2013-10-14 Cleveland Clinic Foundation Myeloperoxidase, en risikoindikator for cardiovasculær sygdom
US7459286B1 (en) 2003-10-22 2008-12-02 The Cleveland Clinic Foundation Assessing the risk of a major adverse cardiac event in patients with chest pain
US20100228600A1 (en) * 2009-03-09 2010-09-09 Eric Lempel System and method for sponsorship recognition
US20110287468A1 (en) * 2010-04-19 2011-11-24 General Atomics Methods and compositions for assaying enzymatic activity of myeloperoxidase in blood samples

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3087794A (en) * 1960-05-23 1963-04-30 Miles Lab Chemical test for differentiating leucocytes from erythrocytes
IT986838B (it) * 1972-05-12 1975-01-30 Sclavo Inst Sieroterapeut Complesso di reagenti per la deter minazione enzimatica del glucosio sistema glucosio ossidasi perossi dasi con metodo manuale e automati co con lettura a termine o in cinetica
DE2856487A1 (de) * 1977-12-29 1979-07-12 Wako Pure Chem Ind Ltd Verfahren zur bestimmung von peroxidischen substanzen und hierfuer brauchbare verbindungen
JPS56145352A (en) * 1980-04-14 1981-11-12 Kyowa Hakko Kogyo Co Ltd Quantifying method for material peroxide
ZA841078B (en) * 1983-03-01 1984-09-26 Warner Lambert Co Peroxidase activity detection composition
JPS614960A (ja) * 1984-06-19 1986-01-10 Fuji Photo Film Co Ltd 分析試薬および多層化学分析要素
US4755472A (en) * 1986-01-16 1988-07-05 Miles Inc. Stable composition for the determination of peroxidatively active substances

Also Published As

Publication number Publication date
EP0418486A3 (en) 1991-11-06
EP0418486B1 (en) 1994-11-02
DK0418486T3 (da) 1994-11-21
DE69013834T2 (de) 1995-03-23
DE69013834D1 (de) 1994-12-08
IT8921788A0 (it) 1989-09-21
EP0418486A2 (en) 1991-03-27
ATE113663T1 (de) 1994-11-15
US5128265A (en) 1992-07-07

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