IE49547B1 - Pyrimidine derivatives - Google Patents
Pyrimidine derivativesInfo
- Publication number
- IE49547B1 IE49547B1 IE477/80A IE47780A IE49547B1 IE 49547 B1 IE49547 B1 IE 49547B1 IE 477/80 A IE477/80 A IE 477/80A IE 47780 A IE47780 A IE 47780A IE 49547 B1 IE49547 B1 IE 49547B1
- Authority
- IE
- Ireland
- Prior art keywords
- pyrimidine
- hydroxy
- isopropylamino
- general formula
- hydroxy group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/47—One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7908494 | 1979-03-10 | ||
GB7914987 | 1979-04-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
IE800477L IE800477L (en) | 1980-09-10 |
IE49547B1 true IE49547B1 (en) | 1985-10-30 |
Family
ID=26270867
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IE477/80A IE49547B1 (en) | 1979-03-10 | 1980-03-07 | Pyrimidine derivatives |
Country Status (24)
Country | Link |
---|---|
JP (1) | JPS55122768A (fi) |
AR (1) | AR222691A1 (fi) |
AU (1) | AU533547B2 (fi) |
BE (1) | BE881752A (fi) |
CA (1) | CA1132561A (fi) |
CH (1) | CH644368A5 (fi) |
DE (3) | DE3009071C2 (fi) |
EG (1) | EG14282A (fi) |
FI (1) | FI66357C (fi) |
FR (2) | FR2451191A1 (fi) |
GB (1) | GB2045756B (fi) |
HK (1) | HK55383A (fi) |
IE (1) | IE49547B1 (fi) |
IN (1) | IN153791B (fi) |
LU (1) | LU82185A1 (fi) |
MX (1) | MX6218E (fi) |
MY (1) | MY8400200A (fi) |
NL (1) | NL184833C (fi) |
NO (1) | NO154054C (fi) |
NZ (1) | NZ192927A (fi) |
OA (1) | OA06484A (fi) |
PT (1) | PT70882A (fi) |
SE (1) | SE435180B (fi) |
SG (1) | SG22683G (fi) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE894517A (fr) * | 1981-10-16 | 1983-01-17 | Sod Conseils Rech Applic | Nouveau derive de l'isopropylamino pyrimidine, sa preparation et composition therapeutiques a base de ses composes |
US4673677A (en) * | 1983-10-03 | 1987-06-16 | Pfizer Inc. | Method for treatment of gastrointestinal disorders |
US4554276A (en) * | 1983-10-03 | 1985-11-19 | Pfizer Inc. | 2-Amino-5-hydroxy-4-methylpyrimidine derivatives |
US4711888A (en) | 1985-07-24 | 1987-12-08 | Pfizer Inc. | Hydroxy and alkoxy pyrimidines |
WO1989000423A1 (en) * | 1987-07-09 | 1989-01-26 | Pfizer Inc. | 2-amino-5-hydroxy-4-pyrimidones |
US4910204A (en) * | 1988-06-28 | 1990-03-20 | Pfizer Inc. | 2-amino-5-hydroxy-4-pyrimidones |
HU206337B (en) * | 1988-12-29 | 1992-10-28 | Mitsui Petrochemical Ind | Process for producing pyrimidine derivatives and pharmaceutical compositions |
US5264435A (en) * | 1988-12-29 | 1993-11-23 | Mitsui Petrochemical Industries, Ltd. | Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines |
US4940712A (en) * | 1989-05-26 | 1990-07-10 | Pfizer Inc. | Derivatives of hydroxyprimidines as leukotriene synthesis inhibitors |
US5270319A (en) * | 1991-09-09 | 1993-12-14 | Warner-Lambert Company | 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents |
US5220025A (en) * | 1992-02-24 | 1993-06-15 | Warner-Lambert Company | 2-substituted amino-4, 6-di-tertiary-butyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents |
US5196431A (en) * | 1992-02-24 | 1993-03-23 | Warner-Lambert Company | 2-substituted amino-4, 6-di-tertiary-buthyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents |
US9133212B1 (en) * | 2005-06-15 | 2015-09-15 | Vanderbilt University | Inhibitors of hemeprotein-catalyzed lipid peroxidation |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB741667A (en) * | 1952-12-05 | 1955-12-07 | Ici Ltd | New pyrimidine derivatives |
GB756189A (en) * | 1954-02-01 | 1956-08-29 | Ici Ltd | New pyrimidine derivatives |
ZA711152B (en) * | 1970-03-02 | 1971-11-24 | Ici Ltd | Manufacture of pyrimidines |
GB1525995A (en) * | 1976-02-18 | 1978-09-27 | Soc D Etudes Prod Chimique | Aminopyrimidine salt |
-
1980
- 1980-02-12 IN IN103/DEL/80A patent/IN153791B/en unknown
- 1980-02-15 BE BE0/199421A patent/BE881752A/fr not_active IP Right Cessation
- 1980-02-20 NZ NZ192927A patent/NZ192927A/xx unknown
- 1980-02-20 LU LU82185A patent/LU82185A1/fr unknown
- 1980-02-26 FI FI800566A patent/FI66357C/fi not_active IP Right Cessation
- 1980-02-27 AR AR280106A patent/AR222691A1/es active
- 1980-02-29 PT PT70882A patent/PT70882A/pt unknown
- 1980-03-03 CH CH165080A patent/CH644368A5/fr not_active IP Right Cessation
- 1980-03-04 CA CA346,981A patent/CA1132561A/en not_active Expired
- 1980-03-04 NL NLAANVRAGE8001289,A patent/NL184833C/xx not_active IP Right Cessation
- 1980-03-07 GB GB8007908A patent/GB2045756B/en not_active Expired
- 1980-03-07 NO NO800664A patent/NO154054C/no unknown
- 1980-03-07 IE IE477/80A patent/IE49547B1/en unknown
- 1980-03-07 AU AU56248/80A patent/AU533547B2/en not_active Ceased
- 1980-03-07 SE SE8001812A patent/SE435180B/sv not_active IP Right Cessation
- 1980-03-09 EG EG131/80A patent/EG14282A/xx active
- 1980-03-10 FR FR8005277A patent/FR2451191A1/fr active Granted
- 1980-03-10 MX MX808702U patent/MX6218E/es unknown
- 1980-03-10 OA OA57049A patent/OA06484A/xx unknown
- 1980-03-10 FR FR8005278A patent/FR2451370A1/fr active Granted
- 1980-03-10 DE DE3009071A patent/DE3009071C2/de not_active Expired
- 1980-03-10 DE DE3050999A patent/DE3050999C2/de not_active Expired
- 1980-03-10 JP JP2931280A patent/JPS55122768A/ja active Granted
- 1980-04-30 DE DE19803016752 patent/DE3016752A1/de active Granted
-
1983
- 1983-04-28 SG SG226/83A patent/SG22683G/en unknown
- 1983-11-17 HK HK553/83A patent/HK55383A/xx unknown
-
1984
- 1984-12-30 MY MY200/84A patent/MY8400200A/xx unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CH631696A5 (de) | Verfahren zur herstellung von olefinischen derivaten von aminosaeuren. | |
IE49547B1 (en) | Pyrimidine derivatives | |
US4426391A (en) | [(Alkoxycarbonyl)oxy]alkyl esters of methyldopa | |
US4324787A (en) | 2-Oxo-1-pyrrolidineacetic acid compounds and their medicinal use | |
EP0546548A1 (de) | Guanidinalkyl-1,1-bisphosphonsäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung | |
US4073895A (en) | Isopropylamino pyrimidine orthophosphate | |
DE69806189T2 (de) | Acronycinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen | |
US4085214A (en) | Stable pro-drug forms of theophylline | |
US4451473A (en) | 3,7-Diazabicyclo [3.3.1] nonanes having anti-arrhythmic activity | |
GB2054556A (en) | Preparation of hydroxy derivatives of 2-isopropylamino-pyrimidine | |
US4267181A (en) | Halogeno derivatives of isopropylamino pyrimidine and therapeutic use | |
GB2093027A (en) | 2-amino-3-(halobenzoyl)-methylphenylacetic acids, esters and salts thereof | |
EP0058079B1 (en) | 4-(1-imidazolylmethyl)cinnamic acid hydrochloride monohydrate, method of preparation thereof, and pharmaceutical composition containing same | |
US4187311A (en) | 3-Aryloxy-1-carboalkoxyethylpyridinium compounds and compositions | |
US4338320A (en) | Esters of 6'-hydroxycinchonine, and a method of treating arrythmia with them | |
US3553267A (en) | 3-dimethylamino-1,2,3,4-tetrahydrofluorene | |
JP2860385B2 (ja) | ビスべンジルイソキノリン誘導体 | |
KR840001708B1 (ko) | 하이드록시 피리미딘 유도체의 제조방법 | |
GB1565022A (en) | Methylamine derivatives and provesses for preparing the same | |
US4358441A (en) | Nicotinic derivatives of glucosamine and related pharmaceutical compositions | |
GB1565217A (en) | 4-aminoquinolines process for their preparation and pharmaceutical compositions containing them | |
HU209245B (en) | Process for producing new cimetidine derivatives, as well as new gastric acid secretion inhibiting and gastrocytoprotective pharmaceuitcal compositions | |
KR840000910B1 (ko) | 술포늄 화합물의 제조방법 | |
KR840001985B1 (ko) | 이소프로필 아미노-피리미딘 하이드록시 유도체의 제법 | |
EP0172383B1 (en) | Pharmacologically active salt derivatives of 1,2,3,6-tetrahydro-1,3-dimethyl-2,6 dioxopurine-7-acetic acid |