IE49547B1 - Pyrimidine derivatives - Google Patents

Pyrimidine derivatives

Info

Publication number
IE49547B1
IE49547B1 IE477/80A IE47780A IE49547B1 IE 49547 B1 IE49547 B1 IE 49547B1 IE 477/80 A IE477/80 A IE 477/80A IE 47780 A IE47780 A IE 47780A IE 49547 B1 IE49547 B1 IE 49547B1
Authority
IE
Ireland
Prior art keywords
pyrimidine
hydroxy
isopropylamino
general formula
hydroxy group
Prior art date
Application number
IE477/80A
Other languages
English (en)
Other versions
IE800477L (en
Original Assignee
Soc D Etudes Prod Chimique
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26270867&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IE49547(B1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Soc D Etudes Prod Chimique filed Critical Soc D Etudes Prod Chimique
Publication of IE800477L publication Critical patent/IE800477L/xx
Publication of IE49547B1 publication Critical patent/IE49547B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/47One nitrogen atom and one oxygen or sulfur atom, e.g. cytosine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D239/00Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/46Two or more oxygen, sulphur or nitrogen atoms
    • C07D239/52Two oxygen atoms
    • C07D239/54Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
    • C07D239/545Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IE477/80A 1979-03-10 1980-03-07 Pyrimidine derivatives IE49547B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB7908494 1979-03-10
GB7914987 1979-04-30

Publications (2)

Publication Number Publication Date
IE800477L IE800477L (en) 1980-09-10
IE49547B1 true IE49547B1 (en) 1985-10-30

Family

ID=26270867

Family Applications (1)

Application Number Title Priority Date Filing Date
IE477/80A IE49547B1 (en) 1979-03-10 1980-03-07 Pyrimidine derivatives

Country Status (24)

Country Link
JP (1) JPS55122768A (fi)
AR (1) AR222691A1 (fi)
AU (1) AU533547B2 (fi)
BE (1) BE881752A (fi)
CA (1) CA1132561A (fi)
CH (1) CH644368A5 (fi)
DE (3) DE3009071C2 (fi)
EG (1) EG14282A (fi)
FI (1) FI66357C (fi)
FR (2) FR2451191A1 (fi)
GB (1) GB2045756B (fi)
HK (1) HK55383A (fi)
IE (1) IE49547B1 (fi)
IN (1) IN153791B (fi)
LU (1) LU82185A1 (fi)
MX (1) MX6218E (fi)
MY (1) MY8400200A (fi)
NL (1) NL184833C (fi)
NO (1) NO154054C (fi)
NZ (1) NZ192927A (fi)
OA (1) OA06484A (fi)
PT (1) PT70882A (fi)
SE (1) SE435180B (fi)
SG (1) SG22683G (fi)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE894517A (fr) * 1981-10-16 1983-01-17 Sod Conseils Rech Applic Nouveau derive de l'isopropylamino pyrimidine, sa preparation et composition therapeutiques a base de ses composes
US4673677A (en) * 1983-10-03 1987-06-16 Pfizer Inc. Method for treatment of gastrointestinal disorders
US4554276A (en) * 1983-10-03 1985-11-19 Pfizer Inc. 2-Amino-5-hydroxy-4-methylpyrimidine derivatives
US4711888A (en) 1985-07-24 1987-12-08 Pfizer Inc. Hydroxy and alkoxy pyrimidines
WO1989000423A1 (en) * 1987-07-09 1989-01-26 Pfizer Inc. 2-amino-5-hydroxy-4-pyrimidones
US4910204A (en) * 1988-06-28 1990-03-20 Pfizer Inc. 2-amino-5-hydroxy-4-pyrimidones
HU206337B (en) * 1988-12-29 1992-10-28 Mitsui Petrochemical Ind Process for producing pyrimidine derivatives and pharmaceutical compositions
US5264435A (en) * 1988-12-29 1993-11-23 Mitsui Petrochemical Industries, Ltd. Pyrimidines and their pharmaceutical acceptable salts, and their use as medicines
US4940712A (en) * 1989-05-26 1990-07-10 Pfizer Inc. Derivatives of hydroxyprimidines as leukotriene synthesis inhibitors
US5270319A (en) * 1991-09-09 1993-12-14 Warner-Lambert Company 5-hydroxy-2-pyrimidinylmethylene derivatives useful as antiinflammatory agents
US5220025A (en) * 1992-02-24 1993-06-15 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-butyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
US5196431A (en) * 1992-02-24 1993-03-23 Warner-Lambert Company 2-substituted amino-4, 6-di-tertiary-buthyl-5-hydroxy-1, 3-pyrimidines as antiinflammatory agents
US9133212B1 (en) * 2005-06-15 2015-09-15 Vanderbilt University Inhibitors of hemeprotein-catalyzed lipid peroxidation

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB741667A (en) * 1952-12-05 1955-12-07 Ici Ltd New pyrimidine derivatives
GB756189A (en) * 1954-02-01 1956-08-29 Ici Ltd New pyrimidine derivatives
ZA711152B (en) * 1970-03-02 1971-11-24 Ici Ltd Manufacture of pyrimidines
GB1525995A (en) * 1976-02-18 1978-09-27 Soc D Etudes Prod Chimique Aminopyrimidine salt

Also Published As

Publication number Publication date
FI66357C (fi) 1984-10-10
HK55383A (en) 1983-11-25
FI800566A (fi) 1980-09-11
GB2045756B (en) 1983-01-26
DE3009071A1 (de) 1980-09-11
EG14282A (en) 1983-09-30
NZ192927A (en) 1981-07-13
JPS55122768A (en) 1980-09-20
SE435180B (sv) 1984-09-10
DE3050999C2 (de) 1986-08-14
PT70882A (en) 1980-03-01
LU82185A1 (fr) 1980-06-06
DE3016752A1 (de) 1980-12-04
NL184468B (nl) 1989-03-01
IN153791B (fi) 1984-08-18
FR2451191A1 (fr) 1980-10-10
NO154054C (no) 1986-07-09
OA06484A (fr) 1981-07-31
SE8001812L (sv) 1980-09-11
NL184833C (nl) 1989-11-16
DE3050999A1 (fi) 1985-08-14
FR2451191B1 (fi) 1983-04-29
DE3009071C2 (de) 1985-11-14
SG22683G (en) 1983-12-16
NO800664L (no) 1980-09-11
FI66357B (fi) 1984-06-29
GB2045756A (en) 1980-11-05
FR2451370B1 (fi) 1983-05-13
CH644368A5 (en) 1984-07-31
MX6218E (es) 1984-12-21
FR2451370A1 (fr) 1980-10-10
NL184833B (nl) 1989-06-16
AU533547B2 (en) 1983-12-01
JPS6126996B2 (fi) 1986-06-23
AR222691A1 (es) 1981-06-15
AU5624880A (en) 1980-09-18
CA1132561A (en) 1982-09-28
DE3016752C2 (fi) 1987-06-25
IE800477L (en) 1980-09-10
NO154054B (no) 1986-04-01
NL8001289A (nl) 1980-09-12
MY8400200A (en) 1984-12-31
BE881752A (fr) 1980-05-30

Similar Documents

Publication Publication Date Title
CH631696A5 (de) Verfahren zur herstellung von olefinischen derivaten von aminosaeuren.
IE49547B1 (en) Pyrimidine derivatives
US4426391A (en) [(Alkoxycarbonyl)oxy]alkyl esters of methyldopa
US4324787A (en) 2-Oxo-1-pyrrolidineacetic acid compounds and their medicinal use
EP0546548A1 (de) Guanidinalkyl-1,1-bisphosphonsäurederivate, Verfahren zu ihrer Herstellung und ihre Verwendung
US4073895A (en) Isopropylamino pyrimidine orthophosphate
DE69806189T2 (de) Acronycinderivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
US4085214A (en) Stable pro-drug forms of theophylline
US4451473A (en) 3,7-Diazabicyclo [3.3.1] nonanes having anti-arrhythmic activity
GB2054556A (en) Preparation of hydroxy derivatives of 2-isopropylamino-pyrimidine
US4267181A (en) Halogeno derivatives of isopropylamino pyrimidine and therapeutic use
GB2093027A (en) 2-amino-3-(halobenzoyl)-methylphenylacetic acids, esters and salts thereof
EP0058079B1 (en) 4-(1-imidazolylmethyl)cinnamic acid hydrochloride monohydrate, method of preparation thereof, and pharmaceutical composition containing same
US4187311A (en) 3-Aryloxy-1-carboalkoxyethylpyridinium compounds and compositions
US4338320A (en) Esters of 6'-hydroxycinchonine, and a method of treating arrythmia with them
US3553267A (en) 3-dimethylamino-1,2,3,4-tetrahydrofluorene
JP2860385B2 (ja) ビスべンジルイソキノリン誘導体
KR840001708B1 (ko) 하이드록시 피리미딘 유도체의 제조방법
GB1565022A (en) Methylamine derivatives and provesses for preparing the same
US4358441A (en) Nicotinic derivatives of glucosamine and related pharmaceutical compositions
GB1565217A (en) 4-aminoquinolines process for their preparation and pharmaceutical compositions containing them
HU209245B (en) Process for producing new cimetidine derivatives, as well as new gastric acid secretion inhibiting and gastrocytoprotective pharmaceuitcal compositions
KR840000910B1 (ko) 술포늄 화합물의 제조방법
KR840001985B1 (ko) 이소프로필 아미노-피리미딘 하이드록시 유도체의 제법
EP0172383B1 (en) Pharmacologically active salt derivatives of 1,2,3,6-tetrahydro-1,3-dimethyl-2,6 dioxopurine-7-acetic acid