IE43768B1 - Oximes - Google Patents

Oximes

Info

Publication number
IE43768B1
IE43768B1 IE567/76A IE56776A IE43768B1 IE 43768 B1 IE43768 B1 IE 43768B1 IE 567/76 A IE567/76 A IE 567/76A IE 56776 A IE56776 A IE 56776A IE 43768 B1 IE43768 B1 IE 43768B1
Authority
IE
Ireland
Prior art keywords
formula
group
compound
oxime
pharmaceutically acceptable
Prior art date
Application number
IE567/76A
Other languages
English (en)
Other versions
IE43768L (en
Original Assignee
Duphar Int Res
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Duphar Int Res filed Critical Duphar Int Res
Publication of IE43768L publication Critical patent/IE43768L/xx
Publication of IE43768B1 publication Critical patent/IE43768B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32Oximes
    • C07C251/50Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
    • C07C251/58Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C249/00Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C249/04Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes
    • C07C249/08Preparation of compounds containing nitrogen atoms doubly-bound to a carbon skeleton of oximes by reaction of hydroxylamines with carbonyl compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IE567/76A 1975-03-20 1976-03-18 Oximes IE43768B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL7503310A NL7503310A (nl) 1975-03-20 1975-03-20 Verbindingen met antidepressieve werking.

Publications (2)

Publication Number Publication Date
IE43768L IE43768L (en) 1976-09-20
IE43768B1 true IE43768B1 (en) 1981-05-20

Family

ID=19823424

Family Applications (1)

Application Number Title Priority Date Filing Date
IE567/76A IE43768B1 (en) 1975-03-20 1976-03-18 Oximes

Country Status (27)

Country Link
US (1) US4085225A (OSRAM)
JP (1) JPS6026776B2 (OSRAM)
AR (2) AR211011A1 (OSRAM)
AT (1) AT340895B (OSRAM)
AU (1) AU505358B2 (OSRAM)
BE (1) BE839744A (OSRAM)
CA (1) CA1076142A (OSRAM)
CH (4) CH626057A5 (OSRAM)
DD (1) DD128332A5 (OSRAM)
DE (1) DE2610886A1 (OSRAM)
DK (1) DK144942C (OSRAM)
ES (1) ES446192A1 (OSRAM)
FI (1) FI61875C (OSRAM)
FR (1) FR2304336A1 (OSRAM)
GB (1) GB1535226A (OSRAM)
GR (1) GR60052B (OSRAM)
HU (1) HU171030B (OSRAM)
IE (1) IE43768B1 (OSRAM)
IL (1) IL49238A (OSRAM)
IT (1) IT1063064B (OSRAM)
MX (1) MX9203723A (OSRAM)
NL (1) NL7503310A (OSRAM)
PL (3) PL100614B1 (OSRAM)
SE (1) SE410312B (OSRAM)
SU (3) SU635867A3 (OSRAM)
YU (1) YU39345B (OSRAM)
ZA (1) ZA761434B (OSRAM)

Families Citing this family (66)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1110460B (it) * 1977-03-02 1985-12-23 Ciba Geigy Ag Prodotti che favoriscono la crescita delle piante e prodotti che proteggono le piante a base di eteri di ossime e di esteri di ossime loro preparazione e loro impiego
FR2639942B1 (fr) * 1988-12-02 1991-03-29 Sanofi Sa Ethers oximes de propenone, procede pour leur preparation et compositions pharmaceutiques les contenant
US5665756A (en) * 1994-08-03 1997-09-09 Hoechst Marion Roussel, Inc. Aminoalkyloximes useful in the treatment of depression and obsessive compulsive disorders
US6548084B2 (en) * 1995-07-20 2003-04-15 Smithkline Beecham Plc Controlled release compositions
AU6776196A (en) * 1995-08-16 1997-03-12 Eli Lilly And Company Potentiation of serotonin response
IN182588B (OSRAM) 1998-05-12 1999-05-08 Sun Pharmaceutical Ind Ltd
IE990406A1 (en) 1999-05-20 2000-12-27 Elan Corp Plc Multiparticulate controlled release selective serotonin reuptake inhibitor formulations.
IN186677B (OSRAM) 1999-11-12 2001-10-20 Sun Pharmaceutical Ind Ltd
AU5702201A (en) * 2000-04-13 2001-10-30 Mayo Foundation Abeta<sub>42</sub> lowering agents
US20080021085A1 (en) * 2000-04-13 2008-01-24 Mayo Foundation For Medical Education And Research Method of reducing abeta42 and treating diseases
WO2001080845A2 (en) * 2000-04-24 2001-11-01 Aryx Therapeutics (2-aminoethyl) oxime derivatives for the treatment of depression
US7256191B2 (en) * 2000-04-24 2007-08-14 Aryx Therapeutics Materials and methods for the treatment of depression
CN101921267A (zh) * 2001-10-12 2010-12-22 阿泽范药品公司 β-内酰胺后叶加压素V1a拮抗剂
CA2477088A1 (en) 2002-02-22 2003-10-02 New River Pharmaceuticals Inc. Active agent delivery systems and methods for protecting and administering active agents
WO2004071431A2 (en) * 2003-02-05 2004-08-26 Myriad Genetics, Inc. Method and composition for treating neurodegenerative disorders
AU2004311577A1 (en) * 2003-07-11 2005-07-21 Myriad Genetics, Inc. Pharmaceutical methods, dosing regimes and dosage forms for the treatment of Alzheimer's disease
CA2537402C (en) 2003-09-12 2009-05-05 Pfizer Inc. Combinations comprising alpha-2-delta ligands and serotonin / noradrenaline re-uptake inhibitors
WO2005051919A1 (en) * 2003-11-26 2005-06-09 Pfizer Products Inc. Aminopyrazole derivatives as gsk-3 inhibitors
PL1691811T3 (pl) 2003-12-11 2014-12-31 Sunovion Pharmaceuticals Inc Skojarzenie leku uspokajającego i modulatora neuroprzekaźnikowego oraz sposoby poprawy jakości snu i leczenia depresji
US20070293538A1 (en) * 2004-04-13 2007-12-20 Myriad Genetics, Incorporated Pharmaceutical Composition And Methods For Treating Neurodegenerative Disorders
EP1737473A4 (en) * 2004-04-19 2009-08-26 Noven Therapeutics Llc COMBINATIONS OF LITHIUM AND USES THEREOF
US20050252144A1 (en) * 2004-04-29 2005-11-17 Macdonald Robert A Veneers for walls, retaining walls and the like
WO2006020852A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020850A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
WO2006020853A2 (en) * 2004-08-11 2006-02-23 Myriad Genetics, Inc. Pharmaceutical composition and method for treating neurodegenerative disorders
US9597314B2 (en) 2005-03-22 2017-03-21 Azevan Pharmaceuticals, Inc. Beta-lactamylalkanoic acids for treating premenstrual disorders
CN101163689A (zh) * 2005-04-22 2008-04-16 惠氏公司 {[(2r)-7-(2,6-二氯苯基)-5-氟-2,3-二氢-1-苯并呋喃-2-基]甲基}胺盐酸盐的晶形
CA2604916A1 (en) 2005-04-22 2006-11-02 Wyeth Dihydrobenzofuran derivatives and uses thereof
TW200719886A (en) * 2005-04-22 2007-06-01 Wyeth Corp Dihydrobenzofuran derivatives and uses thereof
CA2605554A1 (en) * 2005-04-22 2006-11-02 Wyeth Benzofuranyl alkanamine derivatives and uses thereof as 5-ht2c agonists
WO2007008758A2 (en) 2005-07-08 2007-01-18 Braincells, Inc. Methods for identifying agents and conditions that modulate neurogenesis
US20070015832A1 (en) * 2005-07-14 2007-01-18 Myriad Genetics, Incorporated Methods of treating overactive bladder and urinary incontinence
US8048874B2 (en) 2005-07-19 2011-11-01 Azevan Pharmaceuticals, Inc. Beta-lactamyl phenylalanine, cysteine, and serine vasopressin antagonists
NZ564789A (en) * 2005-07-22 2010-07-30 Myriad Genetics Inc High drug load formulations and dosage forms
JP2009512711A (ja) 2005-10-21 2009-03-26 ブレインセルス,インコーポレイティド Pde阻害による神経新生の調節
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
FR2912057B1 (fr) * 2007-02-07 2009-04-17 Sanofi Aventis Sa Composition pharmaceutique contenant en association le saredutant et un inhibiteur selectif de la recapture de la serotonine ou un inhibiteur de la recapture de la serotonine/norepinephrine
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
KR20080105104A (ko) * 2006-03-24 2008-12-03 와이어쓰 우울증 치료를 위한 신규한 치료학적 병용제
JP4615470B2 (ja) * 2006-03-29 2011-01-19 卓郎 簑和田 大脳の認知力を用いた疾患治療・予防の方法および医薬
US7858611B2 (en) * 2006-05-09 2010-12-28 Braincells Inc. Neurogenesis by modulating angiotensin
WO2007134136A2 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
EP2026813A2 (en) 2006-05-09 2009-02-25 Braincells, Inc. 5 ht receptor mediated neurogenesis
EP2046119A2 (en) * 2006-07-07 2009-04-15 Myriad Genetics, Inc. Treatment of psychiatric disorders
TW200817003A (en) * 2006-07-31 2008-04-16 Sanofi Aventis Pharmaceutical composition comprising, in combination, saredutant and a selective serotonin peuptake inhibitor or a serotonin/norepinephrine reuptake inhibitor
WO2008030651A1 (en) 2006-09-08 2008-03-13 Braincells, Inc. Combinations containing a 4-acylaminopyridine derivative
US20100016274A1 (en) * 2006-09-14 2010-01-21 Koppel Gary A Beta-lactam cannabinoid receptor modulators
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20080167363A1 (en) * 2006-12-28 2008-07-10 Braincells, Inc Modulation of Neurogenesis By Melatoninergic Agents
CA2675132A1 (en) * 2007-01-11 2008-07-17 Braincells, Inc. Modulation of neurogenesis with use of modafinil
WO2009128058A1 (en) 2008-04-18 2009-10-22 UNIVERSITY COLLEGE DUBLIN, NATIONAL UNIVERSITY OF IRELAND, DUBLIN et al Psycho-pharmaceuticals
US20100092479A1 (en) * 2008-08-18 2010-04-15 Combinatorx (Singapore) Pte. Ltd. Compositions and methods for treatment of viral diseases
WO2010099217A1 (en) 2009-02-25 2010-09-02 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
SI2491038T1 (sl) 2009-10-23 2016-08-31 Janssen Pharmaceutica N.V. Disubstituirani oktahil-dropirolo(3,4-c)piroli kot modulatorji oreksinskega receptorja
CA2783699C (en) 2009-12-08 2019-01-15 Case Western Reserve University Primary amine compounds for treating ocular disorders
ES2662350T3 (es) 2010-07-01 2018-04-06 Azevan Pharmaceuticals, Inc. Procedimientos para el tratamiento del trastorno por estrés postraumático
EP2685966A1 (en) 2011-03-17 2014-01-22 Lupin Limited Controlled release pharmaceutical compositions of selective serotonin reuptake inhibitor
KR101427221B1 (ko) * 2012-08-29 2014-08-13 주식회사 에스텍파마 플루복사민 자유 염기의 정제방법 및 이를 이용한 고순도 플루복사민 말레이트의 제조방법
PT2981518T (pt) * 2013-04-03 2021-06-04 Zcl Chemicals Ltd Um processo melhorado para a preparação de maleato de fluvoxamina
PL3104847T3 (pl) 2014-02-07 2021-07-05 Támogatott Kutatócsoportok Irodája Nowe zastosowanie związków agonistycznych receptora sigma-1
MX382453B (es) 2014-03-28 2025-03-13 Azevan Pharmaceuticals Inc Composiciones y metodos para tratar enfermedades neurodegenerativas
PH12018501903B1 (en) 2016-03-10 2023-03-17 Janssen Pharmaceutica Nv Methods of treating depression using orexin-2 receptor antagonists
US12239125B2 (en) 2016-11-24 2025-03-04 SigmaDrugs Kutató Korlátolt Felelsség Társaság Compositions for organ preservation
CN111295373B (zh) 2017-09-15 2024-12-10 阿泽凡药物公司 用于治疗脑损伤的组合物和方法
WO2021016112A2 (en) 2019-07-19 2021-01-28 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens
US11806334B1 (en) 2023-01-12 2023-11-07 Bioxcel Therapeutics, Inc. Non-sedating dexmedetomidine treatment regimens

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3692835A (en) * 1967-04-05 1972-09-19 Jan Van Dijk Pharmacologically active amino-ethyl oximes

Also Published As

Publication number Publication date
AU505358B2 (en) 1979-11-15
DK144942B (da) 1982-07-12
NL7503310A (nl) 1976-09-22
YU39345B (en) 1984-10-31
JPS51125345A (en) 1976-11-01
AR211153A1 (es) 1977-10-31
SU645559A3 (ru) 1979-01-30
IE43768L (en) 1976-09-20
FI760699A7 (OSRAM) 1976-09-21
AR211011A1 (es) 1977-10-14
AU1214776A (en) 1977-09-22
DE2610886A1 (de) 1976-10-07
MX9203723A (es) 1992-07-01
SE410312B (sv) 1979-10-08
FR2304336B1 (OSRAM) 1979-09-28
DD128332A5 (de) 1977-11-09
PL100614B1 (pl) 1978-10-31
US4085225A (en) 1978-04-18
IT1063064B (it) 1985-02-11
SE7603341L (sv) 1976-09-21
AT340895B (de) 1978-01-10
FI61875C (fi) 1982-10-11
CH629477A5 (de) 1982-04-30
SU620206A3 (ru) 1978-08-15
FI61875B (fi) 1982-06-30
YU71476A (en) 1982-10-31
CH629761A5 (de) 1982-05-14
FR2304336A1 (fr) 1976-10-15
ATA195476A (de) 1977-05-15
JPS6026776B2 (ja) 1985-06-25
HU171030B (hu) 1977-10-28
DK144942C (da) 1982-12-06
SU635867A3 (ru) 1978-11-30
GR60052B (en) 1978-04-04
ES446192A1 (es) 1977-10-01
IL49238A0 (en) 1976-05-31
PL100052B1 (pl) 1978-08-31
CH626057A5 (OSRAM) 1981-10-30
CA1076142A (en) 1980-04-22
ZA761434B (en) 1977-10-26
PL101951B1 (pl) 1979-02-28
CH629184A5 (de) 1982-04-15
DK115976A (da) 1976-09-21
IL49238A (en) 1978-08-31
DE2610886C2 (OSRAM) 1987-09-24
BE839744A (fr) 1976-09-20
GB1535226A (en) 1978-12-13

Similar Documents

Publication Publication Date Title
IE43768B1 (en) Oximes
EP0170213B1 (en) Glutarimide antianxiety and antihypertensive agents
RU2434851C1 (ru) Циклические n, n&#39;-диарилтиомочевины или n, n&#39;-диарилмочевины - антагонисты андрогенных рецепторов, противораковое средство, способ получения и применения
SK285165B6 (sk) Tetrahydropyridoétery, farmaceutický prostriedok s ich obsahom a ich použitie
US4575508A (en) 2-Substituted 1-(3&#39;-aminoalkyl)-1,2,3,4-tetrahydro-β-carbolines, and their use as antiarrhythmic agents
JPS63295589A (ja) 生理活性物質k−252の誘導体
JPH03170481A (ja) 置換ピリミドベンズイミダゾール誘導体
RU2138501C1 (ru) Имидазопиридиназолидиноны, их соли и лекарственное средство
US4081551A (en) Oxime ethers having anti-depressive activity
HU182070B (en) Process for producing phenyl-piperazine derivatives
US4086361A (en) Aminoethyl oximes having anti-depressive activity
IE902788A1 (en) 2,3-Dihydro-1-(pyridinylamino)-indoles, a process for their preparation and their use as medicaments
EP0315112B1 (en) Novel amide compounds
HK24194A (en) Pyrrolo[1,2-a][4,1]benzoxazepines, process for their preparation, pharmaceutical compositions containing these compounds and therapeutical use
KR100382998B1 (ko) 6-메톡시-1h-벤조트리아졸-5-카르복사미드유도체,그제조방법및그것을함유하는의약조성물
US4060631A (en) Aminoethyl oxime ethers having anti-depressive activity
US4081552A (en) Oxime ethers having anti-depressive activity
US3262978A (en) O-arylamino-and-aralkyl-amino-alkylhydroxyl-amines
GB2100261A (en) Aminophenylalkylamine derivatives, a process for their preparation and their use as pharmaceuticals
HU184965B (en) Process for producing phenyl-piperazine derivatives of anti-agression activity
WO1997040046A1 (en) Benzoquinolizine derivatives and medicinal compositions
EP0084292A1 (en) N,N-disubstituted alkenamides and phenylalkenamides, processes for their production and their use as pharmaceuticals
FI74004C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara piperazinylpyrido/2,3-b/- och -/3,4-b/ pyrazinderivat.
JPS6342625B2 (OSRAM)
JPH0533950B2 (OSRAM)

Legal Events

Date Code Title Description
MK9A Patent expired