IE36530B1 - 2-nitro-imidazole derivatives and methods for their preparation - Google Patents
2-nitro-imidazole derivatives and methods for their preparationInfo
- Publication number
- IE36530B1 IE36530B1 IE944/72A IE94472A IE36530B1 IE 36530 B1 IE36530 B1 IE 36530B1 IE 944/72 A IE944/72 A IE 944/72A IE 94472 A IE94472 A IE 94472A IE 36530 B1 IE36530 B1 IE 36530B1
- Authority
- IE
- Ireland
- Prior art keywords
- nitro
- preparation
- methods
- group
- imidazole derivatives
- Prior art date
Links
- 150000004959 2-nitroimidazoles Chemical class 0.000 title abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 125000004005 formimidoyl group Chemical group [H]\N=C(/[H])* 0.000 abstract 2
- -1 formylvinyl Chemical group 0.000 abstract 2
- 125000004174 2-benzimidazolyl group Chemical group [H]N1C(*)=NC2=C([H])C([H])=C([H])C([H])=C12 0.000 abstract 1
- 125000001931 aliphatic group Chemical group 0.000 abstract 1
- 230000000845 anti-microbial effect Effects 0.000 abstract 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004674 methylcarbonyl group Chemical group CC(=O)* 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 125000005504 styryl group Chemical group 0.000 abstract 1
- 125000000391 vinyl group Chemical group [H]C([*])=C([H])[H] 0.000 abstract 1
- 229920002554 vinyl polymer Polymers 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT4297871 | 1971-07-30 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE36530L IE36530L (en) | 1973-01-30 |
| IE36530B1 true IE36530B1 (en) | 1976-11-24 |
Family
ID=11254772
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE944/72A IE36530B1 (en) | 1971-07-30 | 1972-07-05 | 2-nitro-imidazole derivatives and methods for their preparation |
Country Status (27)
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1480192A (en) * | 1975-01-15 | 1977-07-20 | Lepetit Spa | 1-methyl-2-nitro-imidazole-5-methanol derivatives |
| GB1526451A (en) * | 1976-01-27 | 1978-09-27 | Lepetit Spa | Alpha,alpha,1-trimethyl-2-nitroimidazole-5-methanol derivatives |
| US4218460A (en) * | 1976-09-29 | 1980-08-19 | Basf Aktiengesellschaft | Nitroimidazoles |
| US4199592A (en) * | 1978-08-29 | 1980-04-22 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-2-nitroimidazoles |
| ZW24982A1 (en) * | 1981-11-30 | 1983-06-15 | Hoffmann La Roche | 2-nitroimidazoles |
| JPH10338673A (ja) * | 1997-06-04 | 1998-12-22 | Nippon Bayeragrochem Kk | イソニコチン酸ヒドラジド誘導体および有害生物防除剤 |
| ZA200507752B (en) | 2003-03-28 | 2007-01-31 | Threshold Pharmaceuticals Inc | Compositions and methods for treating cancer |
| HRP20120803T1 (hr) | 2005-06-29 | 2012-11-30 | Threshold Pharmaceuticals, Inc. | Prolijekovi alkilatora fosforamidata |
| ES2884044T3 (es) | 2006-12-26 | 2021-12-10 | Immunogenesis Inc | Profármaco alquilante de fosforamidato para el tratamiento del cáncer |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL124627C (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1964-08-12 | |||
| NL143227B (nl) * | 1968-11-15 | 1974-09-16 | Lepetit Spa | Werkwijze ter bereiding van imidazoolderivaten met bactericide werking. |
| US3583985A (en) * | 1969-04-09 | 1971-06-08 | Richardson Merrell Inc | Nitroimidazolyl nitrones |
| US3711495A (en) * | 1970-01-07 | 1973-01-16 | Merck & Co Inc | Isoxazalin-3-yl-substituted-5-nitroimidazoles |
-
1972
- 1972-06-15 DE DE2229248A patent/DE2229248C3/de not_active Expired
- 1972-06-15 DE DE2229223A patent/DE2229223C3/de not_active Expired
- 1972-06-16 BE BE785024A patent/BE785024A/xx not_active IP Right Cessation
- 1972-06-30 FI FI1864/72A patent/FI57255C/fi active
- 1972-07-05 IE IE944/72A patent/IE36530B1/xx unknown
- 1972-07-05 AU AU44228/72A patent/AU462723B2/en not_active Expired
- 1972-07-11 ZA ZA724723A patent/ZA724723B/xx unknown
- 1972-07-11 IL IL39880A patent/IL39880A/en unknown
- 1972-07-13 GB GB3288672A patent/GB1362444A/en not_active Expired
- 1972-07-20 AR AR243170A patent/AR193999A1/es active
- 1972-07-20 AR AR243171A patent/AR193885A1/es active
- 1972-07-20 AR AR243172A patent/AR199084A1/es active
- 1972-07-25 SU SU1812191A patent/SU463263A3/ru active
- 1972-07-25 SU SU1812193A patent/SU466684A3/ru active
- 1972-07-26 US US05/275,415 patent/US3954789A/en not_active Expired - Lifetime
- 1972-07-26 DK DK369072A patent/DK154295C/da not_active IP Right Cessation
- 1972-07-27 JP JP47075507A patent/JPS5038111B1/ja active Pending
- 1972-07-27 JP JP47075508A patent/JPS528832B1/ja active Pending
- 1972-07-27 NL NL727210339A patent/NL148602B/xx not_active IP Right Cessation
- 1972-07-27 NL NL727210340A patent/NL149491B/xx not_active IP Right Cessation
- 1972-07-27 NO NO2693/72A patent/NO135591C/no unknown
- 1972-07-27 NO NO2694/72A patent/NO135592C/no unknown
- 1972-07-27 CS CS7200005305A patent/CS180585B2/cs unknown
- 1972-07-28 FR FR7227293A patent/FR2148073B1/fr not_active Expired
- 1972-07-28 CH CH1127672A patent/CH580596A5/xx not_active IP Right Cessation
- 1972-07-28 RO RO7200079770A patent/RO63048A/ro unknown
- 1972-07-28 CH CH1521175A patent/CH574934A5/xx not_active IP Right Cessation
- 1972-07-28 RO RO7200079771A patent/RO63049A/ro unknown
- 1972-07-28 PL PL1972156989A patent/PL85190B1/pl unknown
- 1972-07-28 AT AT686873A patent/AT323736B/de not_active IP Right Cessation
- 1972-07-28 HU HULE663A patent/HU167622B/hu unknown
- 1972-07-28 PL PL1972156990A patent/PL82980B1/pl unknown
- 1972-07-28 SE SE7209898A patent/SE392615B/xx unknown
- 1972-07-28 CH CH1127772A patent/CH572040A5/xx not_active IP Right Cessation
- 1972-07-28 CH CH1521075A patent/CH574933A5/xx not_active IP Right Cessation
- 1972-07-28 SE SE7209897A patent/SE417711B/xx unknown
- 1972-07-28 HU HULE664A patent/HU164926B/hu unknown
- 1972-07-28 DD DD164754A patent/DD99995A5/xx unknown
- 1972-07-28 RO RO7200079769A patent/RO63047A/ro unknown
- 1972-07-28 RO RO7200075751A patent/RO63453A/ro unknown
- 1972-07-28 LU LU65816D patent/LU65816A1/xx unknown
- 1972-07-28 RO RO71770A patent/RO61517A/ro unknown
- 1972-07-28 PL PL1972175045A patent/PL84350B1/pl unknown
- 1972-07-28 DD DD164752A patent/DD99996A5/xx unknown
- 1972-07-28 PL PL1972163819A patent/PL87673B1/pl unknown
- 1972-07-28 RO RO71769A patent/RO62787A/ro unknown
- 1972-07-28 AT AT652872A patent/AT315164B/de not_active IP Right Cessation
- 1972-07-28 AT AT652772A patent/AT316545B/de not_active IP Right Cessation
- 1972-07-29 ES ES405341A patent/ES405341A1/es not_active Expired
- 1972-07-29 ES ES405343A patent/ES405343A1/es not_active Expired
- 1972-07-31 CA CA148,336A patent/CA997340A/en not_active Expired
-
1973
- 1973-06-27 SU SU7301932092A patent/SU581863A3/ru active
- 1973-08-02 AR AR249413A patent/AR199680A1/es active
- 1973-09-20 ES ES418921A patent/ES418921A1/es not_active Expired
- 1973-12-24 SU SU7301978810A patent/SU567404A3/ru active
-
1975
- 1975-03-18 SE SE7503080A patent/SE417200B/xx not_active IP Right Cessation
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