IE32006B1 - Process for the preparation of the optical isomers of 1-ethyl-2-aminomethylpyrrolidine - Google Patents
Process for the preparation of the optical isomers of 1-ethyl-2-aminomethylpyrrolidineInfo
- Publication number
- IE32006B1 IE32006B1 IE395/68A IE39568A IE32006B1 IE 32006 B1 IE32006 B1 IE 32006B1 IE 395/68 A IE395/68 A IE 395/68A IE 39568 A IE39568 A IE 39568A IE 32006 B1 IE32006 B1 IE 32006B1
- Authority
- IE
- Ireland
- Prior art keywords
- pyrrolidine
- ethyl
- tartrate
- aminomethyl
- optically active
- Prior art date
Links
- UNRBEYYLYRXYCG-UHFFFAOYSA-N (1-ethylpyrrolidin-2-yl)methanamine Chemical class CCN1CCCC1CN UNRBEYYLYRXYCG-UHFFFAOYSA-N 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 3
- 230000003287 optical effect Effects 0.000 title abstract 2
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 abstract 4
- RWRDLPDLKQPQOW-UHFFFAOYSA-N Pyrrolidine Chemical compound C1CCNC1 RWRDLPDLKQPQOW-UHFFFAOYSA-N 0.000 abstract 3
- 238000002425 crystallisation Methods 0.000 abstract 2
- 230000008025 crystallization Effects 0.000 abstract 2
- 150000003892 tartrate salts Chemical class 0.000 abstract 2
- FEWJPZIEWOKRBE-XIXRPRMCSA-N Mesotartaric acid Chemical compound OC(=O)[C@@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-XIXRPRMCSA-N 0.000 abstract 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 239000013078 crystal Substances 0.000 abstract 1
- 229960001270 d- tartaric acid Drugs 0.000 abstract 1
- 239000000706 filtrate Substances 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- FEWJPZIEWOKRBE-LWMBPPNESA-N levotartaric acid Chemical compound OC(=O)[C@@H](O)[C@H](O)C(O)=O FEWJPZIEWOKRBE-LWMBPPNESA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229960001367 tartaric acid Drugs 0.000 abstract 1
- 235000002906 tartaric acid Nutrition 0.000 abstract 1
- 239000011975 tartaric acid Substances 0.000 abstract 1
- 229940095064 tartrate Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/08—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
- C07D207/09—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR104008A FR1528014A (fr) | 1967-04-24 | 1967-04-24 | Procédé de préparation des isomères optiques de la éthyl-1, aminométhyl-2-pyrrolidine |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IE32006L IE32006L (en) | 1968-10-24 |
| IE32006B1 true IE32006B1 (en) | 1973-03-07 |
Family
ID=8629548
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IE395/68A IE32006B1 (en) | 1967-04-24 | 1968-04-05 | Process for the preparation of the optical isomers of 1-ethyl-2-aminomethylpyrrolidine |
Country Status (19)
| Country | Link |
|---|---|
| AT (1) | AT278771B (cs) |
| BE (1) | BE712925A (cs) |
| BR (1) | BR6898525D0 (cs) |
| CH (1) | CH484899A (cs) |
| CS (1) | CS153010B2 (cs) |
| DE (1) | DE1795712A1 (cs) |
| DK (1) | DK129285B (cs) |
| ES (1) | ES352901A1 (cs) |
| FR (1) | FR1528014A (cs) |
| GB (1) | GB1207752A (cs) |
| IE (1) | IE32006B1 (cs) |
| IL (1) | IL29781A (cs) |
| IT (1) | IT954025B (cs) |
| MC (1) | MC715A1 (cs) |
| NL (1) | NL6805746A (cs) |
| OA (1) | OA02787A (cs) |
| PL (1) | PL72570B1 (cs) |
| SE (1) | SE323375B (cs) |
| YU (1) | YU32376B (cs) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL52645A (en) * | 1976-08-05 | 1980-02-29 | Synthelabo | Optically active 1 substituted 2 aminomethyl pyrrolidines stereospecifics synthesis thereof and process for the preparation of optically active 2 methoxy n pyrrolidylmethyl benzamides |
| SE447991B (sv) * | 1982-09-30 | 1987-01-12 | Astra Pharma Prod | Diastereomerer av di-p-toluoyltartrat med 1-etyl-2-aminometylpyrrolidin och forfarande for framstellning av dessa |
| DE4425070A1 (de) * | 1994-07-15 | 1996-01-18 | Degussa | Verfahren zur Herstellung optisch aktiver l-substituierter 2-(Aminomethyl)pyrrolidine |
-
1967
- 1967-04-24 FR FR104008A patent/FR1528014A/fr not_active Expired
-
1968
- 1968-03-29 BE BE712925D patent/BE712925A/xx not_active IP Right Cessation
- 1968-04-02 MC MC754A patent/MC715A1/fr unknown
- 1968-04-03 OA OA53237A patent/OA02787A/xx unknown
- 1968-04-05 IE IE395/68A patent/IE32006B1/xx unknown
- 1968-04-08 IL IL29781A patent/IL29781A/en unknown
- 1968-04-08 DE DE19681795712 patent/DE1795712A1/de active Pending
- 1968-04-19 ES ES352901A patent/ES352901A1/es not_active Expired
- 1968-04-19 YU YU0939/68A patent/YU32376B/xx unknown
- 1968-04-20 IT IT36469/68A patent/IT954025B/it active
- 1968-04-22 GB GB08932/68A patent/GB1207752A/en not_active Expired
- 1968-04-23 PL PL1968126595A patent/PL72570B1/pl unknown
- 1968-04-23 NL NL6805746A patent/NL6805746A/xx unknown
- 1968-04-23 DK DK181368AA patent/DK129285B/da unknown
- 1968-04-23 CH CH596068A patent/CH484899A/fr not_active IP Right Cessation
- 1968-04-23 BR BR198525/68A patent/BR6898525D0/pt unknown
- 1968-04-23 SE SE5404/68A patent/SE323375B/xx unknown
- 1968-04-24 CS CS303668A patent/CS153010B2/cs unknown
- 1968-04-24 AT AT400868A patent/AT278771B/de not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| YU93968A (en) | 1974-04-30 |
| DE1795712A1 (de) | 1973-10-18 |
| BE712925A (cs) | 1968-09-30 |
| CH484899A (fr) | 1970-01-31 |
| FR1528014A (fr) | 1968-06-07 |
| IE32006L (en) | 1968-10-24 |
| IL29781A0 (en) | 1968-06-20 |
| DK129285B (da) | 1974-09-23 |
| DK129285C (cs) | 1975-02-10 |
| GB1207752A (en) | 1970-10-07 |
| SE323375B (cs) | 1970-05-04 |
| OA02787A (fr) | 1970-12-15 |
| NL6805746A (cs) | 1968-10-25 |
| CS153010B2 (cs) | 1974-02-22 |
| AT278771B (de) | 1970-02-10 |
| MC715A1 (fr) | 1969-02-05 |
| IL29781A (en) | 1971-08-25 |
| PL72570B1 (cs) | 1974-08-30 |
| YU32376B (en) | 1974-10-31 |
| IT954025B (it) | 1973-08-30 |
| BR6898525D0 (pt) | 1973-05-10 |
| ES352901A1 (es) | 1969-09-01 |
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