ID27884A - Asam-asam indolealkanoat yang disubstitusikan. - Google Patents

Asam-asam indolealkanoat yang disubstitusikan.

Info

Publication number
ID27884A
ID27884A IDW20002212A ID20002212A ID27884A ID 27884 A ID27884 A ID 27884A ID W20002212 A IDW20002212 A ID W20002212A ID 20002212 A ID20002212 A ID 20002212A ID 27884 A ID27884 A ID 27884A
Authority
ID
Indonesia
Prior art keywords
indolealanic
acids substituted
acids
substituted
indolealanic acids
Prior art date
Application number
IDW20002212A
Other languages
English (en)
Indonesian (id)
Inventor
Michael Lee Jones
David Gunn
John Howard Jones
Michael C Van Zandt
Original Assignee
Inst For Pharm Discovery Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Inst For Pharm Discovery Inc filed Critical Inst For Pharm Discovery Inc
Publication of ID27884A publication Critical patent/ID27884A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hematology (AREA)
  • Neurology (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Biomedical Technology (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
IDW20002212A 1998-03-31 1999-03-31 Asam-asam indolealkanoat yang disubstitusikan. ID27884A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8014398P 1998-03-31 1998-03-31

Publications (1)

Publication Number Publication Date
ID27884A true ID27884A (id) 2001-05-03

Family

ID=22155536

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20002212A ID27884A (id) 1998-03-31 1999-03-31 Asam-asam indolealkanoat yang disubstitusikan.

Country Status (29)

Country Link
US (9) US6214991B1 (zh)
EP (1) EP1066283B1 (zh)
JP (2) JP3494990B2 (zh)
KR (1) KR100584650B1 (zh)
CN (1) CN1205207C (zh)
AP (1) AP2000001929A0 (zh)
AT (1) ATE269861T1 (zh)
AU (1) AU774929B2 (zh)
BG (1) BG65446B1 (zh)
BR (1) BR9909358A (zh)
CA (1) CA2383983C (zh)
CZ (1) CZ300706B6 (zh)
DE (1) DE69918278T2 (zh)
EE (1) EE200000573A (zh)
ES (1) ES2224632T3 (zh)
HU (1) HUP0101672A3 (zh)
ID (1) ID27884A (zh)
IL (2) IL138711A0 (zh)
MX (1) MXPA02003122A (zh)
NO (1) NO20004900L (zh)
NZ (1) NZ507172A (zh)
OA (1) OA11622A (zh)
PL (1) PL201645B1 (zh)
SK (1) SK7522001A3 (zh)
TR (1) TR200002869T2 (zh)
TW (1) TWI243163B (zh)
WO (1) WO1999050268A2 (zh)
YU (1) YU59600A (zh)
ZA (1) ZA200005577B (zh)

Families Citing this family (51)

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CN1205207C (zh) * 1998-03-31 2005-06-08 药品发现学会公司 取代的吲哚链烷酸
TNSN99224A1 (fr) * 1998-12-01 2005-11-10 Inst For Pharm Discovery Inc Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
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AU2001238718A1 (en) * 2000-03-02 2001-09-12 The Institutes For Pharmaceutical Discovery, Llc Compositions containing a substituted indolealkanoic acid and an angiotensin converting enzyme inhibitor
US20020012630A1 (en) * 2000-05-09 2002-01-31 James Nolan Methods for testing compounds useful in treating diabetic complications
WO2002051805A1 (de) 2000-12-27 2002-07-04 Bayer Aktiengesellschaft Indol-derivate
DK1397130T3 (da) 2001-06-20 2007-11-12 Wyeth Corp Substituerede indolsyrederivater som inhibitorer af plasminogenaktivatorinhibitor-1 (PAI-1)
TWI224101B (en) 2001-06-20 2004-11-21 Wyeth Corp Substituted naphthyl indole derivatives as inhibitors of plasminogen activator inhibitor type-1 (PAI-1)
US6770655B2 (en) 2002-01-18 2004-08-03 Aryx Therapeutics 5-HT3 receptor antagonists and methods of use
CA2395871A1 (en) * 2002-07-26 2004-01-26 The Institutes For Pharmaceutical Discovery, Llc Substituted indolealkanoic acids derivatives and formulations containing same for use in treatment of diabetic complications
MXPA05001011A (es) * 2002-07-26 2005-06-08 Inst For Pharm Discovery Inc Derivado de acidos indolalcanoicos substituidos y formulaciones que lo contienen para uso en tratamiento de complicaciones diabeticas.
DK1537078T3 (da) * 2002-08-29 2010-08-02 Merck Sharp & Dohme Indoler med anti-diabetisk aktivitet
ATE411288T1 (de) 2002-12-10 2008-10-15 Wyeth Corp Aryl-, aryloxy- und alkyloxysubstituierte 1h- indol-3-yl-glyoxylsäurederivateals inhibitoren des plasminogenaktivatorinhibitors-1 (pai-1)
UA80453C2 (en) 2002-12-10 2007-09-25 Derivatives of substituted dyhydropyranoindol-3,4-dion as inhibitors of plasminogen activator inhibitor-1 (pai-1)
MXPA05006288A (es) 2002-12-10 2005-08-19 Wyeth Corp Derivados del acido 3-carbonil-1h-indol-1-ilacetico sustituidos como inhibidores del inhibidor del activador de plasminogeno 1 (pai-1).
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TNSN99224A1 (fr) * 1998-12-01 2005-11-10 Inst For Pharm Discovery Inc Methodes de reduction des niveaux de glucose et triglyceride en serum et pour suppression de l'antigenese utilisant les acides la indolealkanoique
AU2001238718A1 (en) * 2000-03-02 2001-09-12 The Institutes For Pharmaceutical Discovery, Llc Compositions containing a substituted indolealkanoic acid and an angiotensin converting enzyme inhibitor

Also Published As

Publication number Publication date
SK7522001A3 (en) 2002-02-05
CZ300706B6 (cs) 2009-07-22
US20120270912A1 (en) 2012-10-25
ZA200005577B (en) 2002-02-11
US7304079B2 (en) 2007-12-04
IL138711A0 (en) 2001-10-31
AU774929B2 (en) 2004-07-15
US6214991B1 (en) 2001-04-10
TWI243163B (en) 2005-11-11
OA11622A (en) 2004-09-16
PL201645B1 (pl) 2009-04-30
WO1999050268A2 (en) 1999-10-07
ATE269861T1 (de) 2004-07-15
US7105514B2 (en) 2006-09-12
US20080214540A1 (en) 2008-09-04
TR200002869T2 (tr) 2000-12-21
EP1066283B1 (en) 2004-06-23
PL348244A1 (en) 2002-05-20
HUP0101672A3 (en) 2002-05-28
NO20004900D0 (no) 2000-09-29
NO20004900L (no) 2000-10-17
US20100324039A1 (en) 2010-12-23
JP2002509931A (ja) 2002-04-02
MXPA02003122A (es) 2004-04-21
CZ20003607A3 (cs) 2001-03-14
JP2003155274A (ja) 2003-05-27
BG104819A (en) 2001-05-31
US6426344B2 (en) 2002-07-30
US8163932B2 (en) 2012-04-24
BG65446B1 (bg) 2008-08-29
US20030018053A1 (en) 2003-01-23
US20010016661A1 (en) 2001-08-23
KR20010042330A (ko) 2001-05-25
YU59600A (sh) 2002-12-10
NZ507172A (en) 2003-10-31
JP3494990B2 (ja) 2004-02-09
US20100137301A1 (en) 2010-06-03
IL138711A (en) 2006-09-05
DE69918278T2 (de) 2005-07-14
CA2383983C (en) 2009-09-29
ES2224632T3 (es) 2005-03-01
WO1999050268A3 (en) 1999-12-16
EE200000573A (et) 2002-04-15
EP1066283A2 (en) 2001-01-10
HUP0101672A2 (hu) 2002-04-29
CN1296485A (zh) 2001-05-23
BR9909358A (pt) 2000-12-12
AP2000001929A0 (en) 2000-09-30
CN1205207C (zh) 2005-06-08
CA2383983A1 (en) 1999-10-07
DE69918278D1 (de) 2004-07-29
KR100584650B1 (ko) 2006-05-30
US7659269B2 (en) 2010-02-09
AU3459599A (en) 1999-10-18
US6730794B2 (en) 2004-05-04
US20070093530A1 (en) 2007-04-26
US20040235933A1 (en) 2004-11-25

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