ID26783A - Proses produksi r-(+)-6-karboksamido-3-n-metilamino-1,2,3,4-tetrahidrokarbazol - Google Patents

Proses produksi r-(+)-6-karboksamido-3-n-metilamino-1,2,3,4-tetrahidrokarbazol

Info

Publication number
ID26783A
ID26783A IDW20002365A ID20002365A ID26783A ID 26783 A ID26783 A ID 26783A ID W20002365 A IDW20002365 A ID W20002365A ID 20002365 A ID20002365 A ID 20002365A ID 26783 A ID26783 A ID 26783A
Authority
ID
Indonesia
Prior art keywords
tetrahidrokarbazol
carboxamoid
methylamino
production process
production
Prior art date
Application number
IDW20002365A
Other languages
English (en)
Indonesian (id)
Inventor
Ian Brackenridge
Caroline Mc Gee
John Knight
David Hartley
Steven Mc Intyre
Original Assignee
Vernalis Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vernalis Ltd filed Critical Vernalis Ltd
Publication of ID26783A publication Critical patent/ID26783A/id

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/80—[b, c]- or [b, d]-condensed
    • C07D209/82—Carbazoles; Hydrogenated carbazoles
    • C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
IDW20002365A 1998-04-16 1999-04-16 Proses produksi r-(+)-6-karboksamido-3-n-metilamino-1,2,3,4-tetrahidrokarbazol ID26783A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9808069.0A GB9808069D0 (en) 1998-04-16 1998-04-16 Novel processes

Publications (1)

Publication Number Publication Date
ID26783A true ID26783A (id) 2001-02-08

Family

ID=10830430

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20002365A ID26783A (id) 1998-04-16 1999-04-16 Proses produksi r-(+)-6-karboksamido-3-n-metilamino-1,2,3,4-tetrahidrokarbazol

Country Status (34)

Country Link
US (1) US6359146B1 (pl)
EP (1) EP1070051B1 (pl)
JP (1) JP4756740B2 (pl)
KR (1) KR100612183B1 (pl)
CN (1) CN1200931C (pl)
AR (1) AR015771A1 (pl)
AU (1) AU3437099A (pl)
BR (1) BR9909627A (pl)
CA (1) CA2328345C (pl)
CY (1) CY1116418T1 (pl)
CZ (1) CZ297303B6 (pl)
DK (1) DK1070051T3 (pl)
EA (1) EA004586B1 (pl)
EE (1) EE05156B1 (pl)
ES (1) ES2541432T3 (pl)
GB (1) GB9808069D0 (pl)
HK (1) HK1037615A1 (pl)
HR (1) HRP20000683B1 (pl)
HU (1) HU230559B1 (pl)
ID (1) ID26783A (pl)
IL (1) IL139017A (pl)
MX (1) MXPA00010127A (pl)
MY (1) MY126530A (pl)
NO (1) NO317883B1 (pl)
PL (1) PL210864B1 (pl)
PT (1) PT1070051E (pl)
SI (1) SI1070051T1 (pl)
SK (1) SK286425B6 (pl)
TR (1) TR200100142T2 (pl)
TW (1) TWI255812B (pl)
UA (1) UA70943C2 (pl)
WO (1) WO1999054302A1 (pl)
YU (1) YU62800A (pl)
ZA (1) ZA200006303B (pl)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010073253A1 (en) * 2008-12-22 2010-07-01 Natco Pharma Limited Method for preparing an optically active frovatriptan
WO2011095803A1 (en) * 2010-02-02 2011-08-11 Generics [Uk] Limited Hplc method for analyzing frovatriptan
EP2816030A1 (en) 2013-06-20 2014-12-24 Duke Chem, S. A. Process for the preparation of frovatriptan and its enantiomer
CN103421855B (zh) * 2013-08-13 2016-04-13 凯莱英医药集团（天津）股份有限公司 一种制备琥珀酸夫罗曲坦关键中间体的方法
CN104529871A (zh) * 2014-12-22 2015-04-22 青岛正大海尔制药有限公司 一种琥珀酸呋罗曲坦的制备方法

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2528267A (en) * 1950-10-31 Eobeet j
NL7514300A (nl) * 1975-12-09 1977-06-13 Stamicarbon Werkwijze voor de bereiding van optisch actief fenylglycineamide.
JPS6259274A (ja) * 1985-05-29 1987-03-14 Sumitomo Pharmaceut Co Ltd 光学活性なフエニルセリン誘導体の製造方法
US5827871A (en) 1991-06-26 1998-10-27 Smithkline Beecham Plc Medicaments 1,2,3,4-tetrahydrocarbazoles and 5-HT1 agonist use thereof
GB9113802D0 (en) 1991-06-26 1991-08-14 Smithkline Beecham Plc Medicaments
US5616603A (en) 1995-05-26 1997-04-01 Smithkline Beecham Plc Enantiomers of carbazole derivatives as 5-HT1 -like agonists
GB9226530D0 (en) * 1992-12-21 1993-02-17 Smithkline Beecham Plc Compounds
IL110255A (en) * 1993-07-16 1998-12-06 Merck & Co Inc Creation and resolution of 2 tert-butylcarboxamidopiprazine
JPH07229341A (ja) * 1994-02-15 1995-08-29 Takero Mori 観音開き扉用ロック
US5618948A (en) 1995-05-26 1997-04-08 Smithkline Beecham P.L.C. Process for preparing an enantiomer of a carbazole derivative
US5917054A (en) 1995-07-18 1999-06-29 Smithkline Beecham P.L.C. Process for preparing enantiomers of carbazole derivatives as 5-HT1 -like agonists

Also Published As

Publication number Publication date
HRP20000683B1 (hr) 2016-01-01
AU3437099A (en) 1999-11-08
CZ20003823A3 (cs) 2001-08-15
ZA200006303B (en) 2001-05-30
CN1200931C (zh) 2005-05-11
HU230559B1 (hu) 2016-12-28
HUP0101445A2 (hu) 2001-09-28
TWI255812B (en) 2006-06-01
HRP20000683A2 (en) 2001-04-30
SI1070051T1 (sl) 2015-07-31
NO20005158D0 (no) 2000-10-13
SK286425B6 (sk) 2008-09-05
GB9808069D0 (en) 1998-06-17
MY126530A (en) 2006-10-31
IL139017A (en) 2005-08-31
US6359146B1 (en) 2002-03-19
WO1999054302A1 (en) 1999-10-28
KR100612183B1 (ko) 2006-08-16
BR9909627A (pt) 2001-11-06
EP1070051A1 (en) 2001-01-24
NO20005158L (no) 2000-10-31
MXPA00010127A (es) 2002-08-06
NO317883B1 (no) 2004-12-27
CY1116418T1 (el) 2017-02-08
JP2002512227A (ja) 2002-04-23
HUP0101445A3 (en) 2002-12-28
TR200100142T2 (tr) 2001-07-23
KR20010042661A (ko) 2001-05-25
PL343528A1 (en) 2001-08-27
EP1070051B1 (en) 2015-06-03
HK1037615A1 (en) 2002-02-15
CN1305460A (zh) 2001-07-25
UA70943C2 (uk) 2004-11-15
CZ297303B6 (cs) 2006-11-15
AR015771A1 (es) 2001-05-16
CA2328345A1 (en) 1999-10-28
ES2541432T3 (es) 2015-07-20
EE05156B1 (et) 2009-04-15
JP4756740B2 (ja) 2011-08-24
DK1070051T3 (en) 2015-07-06
EE200000597A (et) 2002-04-15
EA004586B1 (ru) 2004-06-24
PL210864B1 (pl) 2012-03-30
SK15182000A3 (sk) 2001-06-11
CA2328345C (en) 2010-12-07
PT1070051E (pt) 2015-08-24
IL139017A0 (en) 2001-11-25
YU62800A (sh) 2002-11-15
EA200001080A1 (ru) 2001-06-25

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