HK1037615A1 - Process for the production of R-(+)-6-carboxamido-3-N-methylamino -1,2,3,4-tetrahydrocarbazole. - Google Patents
Process for the production of R-(+)-6-carboxamido-3-N-methylamino -1,2,3,4-tetrahydrocarbazole.Info
- Publication number
- HK1037615A1 HK1037615A1 HK01108166A HK01108166A HK1037615A1 HK 1037615 A1 HK1037615 A1 HK 1037615A1 HK 01108166 A HK01108166 A HK 01108166A HK 01108166 A HK01108166 A HK 01108166A HK 1037615 A1 HK1037615 A1 HK 1037615A1
- Authority
- HK
- Hong Kong
- Prior art keywords
- tetrahydrocarbazole
- carboxamido
- methylamino
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/56—Ring systems containing three or more rings
- C07D209/80—[b, c]- or [b, d]-condensed
- C07D209/82—Carbazoles; Hydrogenated carbazoles
- C07D209/88—Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9808069.0A GB9808069D0 (en) | 1998-04-16 | 1998-04-16 | Novel processes |
| PCT/GB1999/001167 WO1999054302A1 (en) | 1998-04-16 | 1999-04-16 | Process for the production of r-(+)-6- carboxamido- 3-n- methylamino- 1,2,3,4- tetrahydrocarbazole |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HK1037615A1 true HK1037615A1 (en) | 2002-02-15 |
Family
ID=10830430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HK01108166A HK1037615A1 (en) | 1998-04-16 | 2001-11-20 | Process for the production of R-(+)-6-carboxamido-3-N-methylamino -1,2,3,4-tetrahydrocarbazole. |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US6359146B1 (pl) |
| EP (1) | EP1070051B1 (pl) |
| JP (1) | JP4756740B2 (pl) |
| KR (1) | KR100612183B1 (pl) |
| CN (1) | CN1200931C (pl) |
| AR (1) | AR015771A1 (pl) |
| AU (1) | AU3437099A (pl) |
| BR (1) | BR9909627A (pl) |
| CA (1) | CA2328345C (pl) |
| CY (1) | CY1116418T1 (pl) |
| CZ (1) | CZ297303B6 (pl) |
| DK (1) | DK1070051T3 (pl) |
| EA (1) | EA004586B1 (pl) |
| EE (1) | EE05156B1 (pl) |
| ES (1) | ES2541432T3 (pl) |
| GB (1) | GB9808069D0 (pl) |
| HK (1) | HK1037615A1 (pl) |
| HR (1) | HRP20000683B1 (pl) |
| HU (1) | HU230559B1 (pl) |
| ID (1) | ID26783A (pl) |
| IL (1) | IL139017A (pl) |
| MX (1) | MXPA00010127A (pl) |
| MY (1) | MY126530A (pl) |
| NO (1) | NO317883B1 (pl) |
| PL (1) | PL210864B1 (pl) |
| PT (1) | PT1070051E (pl) |
| SI (1) | SI1070051T1 (pl) |
| SK (1) | SK286425B6 (pl) |
| TR (1) | TR200100142T2 (pl) |
| TW (1) | TWI255812B (pl) |
| UA (1) | UA70943C2 (pl) |
| WO (1) | WO1999054302A1 (pl) |
| YU (1) | YU62800A (pl) |
| ZA (1) | ZA200006303B (pl) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010073253A1 (en) * | 2008-12-22 | 2010-07-01 | Natco Pharma Limited | Method for preparing an optically active frovatriptan |
| WO2011095803A1 (en) * | 2010-02-02 | 2011-08-11 | Generics [Uk] Limited | Hplc method for analyzing frovatriptan |
| EP2816030A1 (en) | 2013-06-20 | 2014-12-24 | Duke Chem, S. A. | Process for the preparation of frovatriptan and its enantiomer |
| CN103421855B (zh) * | 2013-08-13 | 2016-04-13 | 凯莱英医药集团（天津）股份有限公司 | 一种制备琥珀酸夫罗曲坦关键中间体的方法 |
| CN104529871A (zh) * | 2014-12-22 | 2015-04-22 | 青岛正大海尔制药有限公司 | 一种琥珀酸呋罗曲坦的制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2528267A (en) * | 1950-10-31 | Eobeet j | ||
| NL7514300A (nl) * | 1975-12-09 | 1977-06-13 | Stamicarbon | Werkwijze voor de bereiding van optisch actief fenylglycineamide. |
| JPS6259274A (ja) * | 1985-05-29 | 1987-03-14 | Sumitomo Pharmaceut Co Ltd | 光学活性なフエニルセリン誘導体の製造方法 |
| US5827871A (en) | 1991-06-26 | 1998-10-27 | Smithkline Beecham Plc | Medicaments 1,2,3,4-tetrahydrocarbazoles and 5-HT1 agonist use thereof |
| GB9113802D0 (en) | 1991-06-26 | 1991-08-14 | Smithkline Beecham Plc | Medicaments |
| US5616603A (en) | 1995-05-26 | 1997-04-01 | Smithkline Beecham Plc | Enantiomers of carbazole derivatives as 5-HT1 -like agonists |
| GB9226530D0 (en) * | 1992-12-21 | 1993-02-17 | Smithkline Beecham Plc | Compounds |
| IL110255A (en) * | 1993-07-16 | 1998-12-06 | Merck & Co Inc | Creation and resolution of 2 tert-butylcarboxamidopiprazine |
| JPH07229341A (ja) * | 1994-02-15 | 1995-08-29 | Takero Mori | 観音開き扉用ロック |
| US5618948A (en) | 1995-05-26 | 1997-04-08 | Smithkline Beecham P.L.C. | Process for preparing an enantiomer of a carbazole derivative |
| US5917054A (en) | 1995-07-18 | 1999-06-29 | Smithkline Beecham P.L.C. | Process for preparing enantiomers of carbazole derivatives as 5-HT1 -like agonists |
-
1998
- 1998-04-16 GB GBGB9808069.0A patent/GB9808069D0/en not_active Ceased
-
1999
- 1999-04-16 MY MYPI99001476A patent/MY126530A/en unknown
- 1999-04-16 MX MXPA00010127A patent/MXPA00010127A/es active IP Right Grant
- 1999-04-16 ES ES99915957.7T patent/ES2541432T3/es not_active Expired - Lifetime
- 1999-04-16 HU HU0101445A patent/HU230559B1/hu unknown
- 1999-04-16 PL PL343528A patent/PL210864B1/pl unknown
- 1999-04-16 AR ARP990101781A patent/AR015771A1/es active IP Right Grant
- 1999-04-16 JP JP2000544643A patent/JP4756740B2/ja not_active Expired - Lifetime
- 1999-04-16 CA CA2328345A patent/CA2328345C/en not_active Expired - Lifetime
- 1999-04-16 IL IL13901799A patent/IL139017A/xx not_active IP Right Cessation
- 1999-04-16 YU YU62800A patent/YU62800A/sh unknown
- 1999-04-16 WO PCT/GB1999/001167 patent/WO1999054302A1/en active IP Right Grant
- 1999-04-16 EA EA200001080A patent/EA004586B1/ru not_active IP Right Cessation
- 1999-04-16 TR TR2001/00142T patent/TR200100142T2/xx unknown
- 1999-04-16 KR KR1020007011362A patent/KR100612183B1/ko active Protection Beyond IP Right Term
- 1999-04-16 EE EEP200000597A patent/EE05156B1/xx unknown
- 1999-04-16 CZ CZ20003823A patent/CZ297303B6/cs not_active IP Right Cessation
- 1999-04-16 ID IDW20002365A patent/ID26783A/id unknown
- 1999-04-16 UA UA2000116417A patent/UA70943C2/uk unknown
- 1999-04-16 SI SI9931077T patent/SI1070051T1/sl unknown
- 1999-04-16 AU AU34370/99A patent/AU3437099A/en not_active Abandoned
- 1999-04-16 SK SK1518-2000A patent/SK286425B6/sk not_active IP Right Cessation
- 1999-04-16 PT PT99915957T patent/PT1070051E/pt unknown
- 1999-04-16 CN CNB998072516A patent/CN1200931C/zh not_active Expired - Lifetime
- 1999-04-16 BR BR9909627-7A patent/BR9909627A/pt not_active Application Discontinuation
- 1999-04-16 DK DK99915957.7T patent/DK1070051T3/en active
- 1999-04-16 EP EP99915957.7A patent/EP1070051B1/en not_active Expired - Lifetime
- 1999-05-03 TW TW088107131A patent/TWI255812B/zh active
-
2000
- 2000-10-13 US US09/689,661 patent/US6359146B1/en not_active Expired - Lifetime
- 2000-10-13 NO NO20005158A patent/NO317883B1/no not_active IP Right Cessation
- 2000-10-16 HR HRP20000683AA patent/HRP20000683B1/hr not_active IP Right Cessation
- 2000-11-03 ZA ZA200006303A patent/ZA200006303B/en unknown
-
2001
- 2001-11-20 HK HK01108166A patent/HK1037615A1/xx unknown
-
2015
- 2015-06-23 CY CY20151100532T patent/CY1116418T1/el unknown
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