ID25534A - Glucagon-seperti kristal peptida-1 - Google Patents

Glucagon-seperti kristal peptida-1

Info

Publication number
ID25534A
ID25534A IDW20001139A ID20001139A ID25534A ID 25534 A ID25534 A ID 25534A ID W20001139 A IDW20001139 A ID W20001139A ID 20001139 A ID20001139 A ID 20001139A ID 25534 A ID25534 A ID 25534A
Authority
ID
Indonesia
Prior art keywords
glucagon
peptides
crystal
crystal peptides
Prior art date
Application number
IDW20001139A
Other languages
English (en)
Indonesian (id)
Inventor
James Arthur Hoffmann
Ronald Norbert Hermeling
Chakravarthy Narasimhan
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ID25534A publication Critical patent/ID25534A/id

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/26—Glucagons
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/605—Glucagons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
IDW20001139A 1997-12-16 1998-12-14 Glucagon-seperti kristal peptida-1 ID25534A (id)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US6972897P 1997-12-16 1997-12-16

Publications (1)

Publication Number Publication Date
ID25534A true ID25534A (id) 2000-10-12

Family

ID=22090845

Family Applications (1)

Application Number Title Priority Date Filing Date
IDW20001139A ID25534A (id) 1997-12-16 1998-12-14 Glucagon-seperti kristal peptida-1

Country Status (24)

Country Link
US (3) US6380357B2 (fr)
EP (1) EP0926159A3 (fr)
JP (1) JP2002508332A (fr)
KR (1) KR20010033146A (fr)
CN (1) CN1281369A (fr)
AR (1) AR019806A1 (fr)
AU (1) AU1821899A (fr)
BR (1) BR9813658A (fr)
CA (1) CA2315243A1 (fr)
CO (1) CO5040043A1 (fr)
CZ (1) CZ20002104A3 (fr)
EA (1) EA200000652A1 (fr)
HR (1) HRP20000409A2 (fr)
HU (1) HUP0100046A2 (fr)
ID (1) ID25534A (fr)
IL (1) IL136377A0 (fr)
NO (1) NO20003081L (fr)
NZ (1) NZ505182A (fr)
PE (1) PE20000059A1 (fr)
PL (1) PL341210A1 (fr)
SV (1) SV1998000147A (fr)
TR (1) TR200001726T2 (fr)
WO (1) WO1999030731A1 (fr)
ZA (1) ZA9811466B (fr)

Families Citing this family (102)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6849708B1 (en) * 1986-05-05 2005-02-01 The General Hospital Corporation Insulinotropic hormone and uses thereof
US7138486B2 (en) 1986-05-05 2006-11-21 The General Hospital Corporation Insulinotropic hormone derivatives and uses thereof
US6380357B2 (en) * 1997-12-16 2002-04-30 Eli Lilly And Company Glucagon-like peptide-1 crystals
US9006175B2 (en) * 1999-06-29 2015-04-14 Mannkind Corporation Potentiation of glucose elimination
PT1196430E (pt) 1999-06-29 2012-04-18 Mannkind Corp Purificação e estabilização de péptidos e proteínas em agentes farmacêuticos
DE60102899T2 (de) 2000-01-27 2005-03-31 Eli Lilly And Co., Indianapolis Verfahren zur lösung von glucagon-ähnlichen peptid-1 (glp-1) verbindungen
US6844321B2 (en) * 2000-01-31 2005-01-18 Novo Nordisk A/S Crystallization of a GLP-1 analogue
AU2001228327A1 (en) * 2000-01-31 2001-08-14 Novo-Nordisk A/S Crystallisation of a glp-1 analogue
WO2001087322A2 (fr) * 2000-05-17 2001-11-22 Bionebraska, Inc. Preparations pharmaceutiques peptidiques
CZ304002B6 (cs) * 2000-06-16 2013-08-14 Eli Lilly And Company Analogy peptidu-1 podobného glukagonu
EP1351984A2 (fr) * 2000-12-13 2003-10-15 Eli Lilly And Company Glp-1 amide
AU3938402A (en) 2000-12-13 2002-06-24 Lilly Co Eli Chronic treatment regimen using glucagon-like insulinotropic peptides
US20030119734A1 (en) * 2001-06-28 2003-06-26 Flink James M. Stable formulation of modified GLP-1
JP4227894B2 (ja) * 2001-08-23 2009-02-18 イーライ リリー アンド カンパニー グルカゴン様ペプチド１アナログ
JP5424521B2 (ja) 2001-12-21 2014-02-26 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド アルブミン融合タンパク質
CN1332711C (zh) * 2002-02-20 2007-08-22 埃米球科技有限公司 施用glp－1分子的方法
EP1894591B1 (fr) 2002-03-20 2013-06-26 MannKind Corporation Cartouche pour un appareil d'inhalation
US20080260838A1 (en) * 2003-08-01 2008-10-23 Mannkind Corporation Glucagon-like peptide 1 (glp-1) pharmaceutical formulations
SG176314A1 (en) 2002-12-31 2011-12-29 Altus Pharmaceuticals Inc Human growth hormone crystals and methods for preparing them
NZ571243A (en) * 2002-12-31 2010-04-30 Altus Pharmaceuticals Inc Complexes of protein crystals and ionic polymers comprising human growth hormone and protamine
US7687625B2 (en) * 2003-03-25 2010-03-30 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7638638B2 (en) 2003-05-14 2009-12-29 Takeda San Diego, Inc. Dipeptidyl peptidase inhibitors
KR101308912B1 (ko) * 2003-06-03 2013-09-23 노보 노르디스크 에이/에스 안정화된 약학적 펩티드 조성물
WO2004105790A1 (fr) * 2003-06-03 2004-12-09 Novo Nordisk A/S Compositions peptidiques pharmaceutiques stabilisees
AU2004243531B2 (en) * 2003-06-03 2009-11-05 Novo Nordisk A/S Stabilized pharmaceutical peptide compositions
US7008957B2 (en) * 2003-07-25 2006-03-07 Sanofi-Aventis Deutschland Gmbh Bicyclic cyanoheterocycles, process for their preparation and their use as medicaments
US7094800B2 (en) * 2003-07-25 2006-08-22 Sanofi-Aventis Deutschland Gmbh Cyanopyrrolidides, process for their preparation and their use as medicaments
US7094794B2 (en) * 2003-07-28 2006-08-22 Sanofi-Aventis Deutschland Gmbh Substituted thiazole-benzoisothiazole dioxide derivatives, process for their preparation and their use
US8921311B2 (en) 2003-08-01 2014-12-30 Mannkind Corporation Method for treating hyperglycemia
DE10335092B3 (de) * 2003-08-01 2005-02-03 Aventis Pharma Deutschland Gmbh Substituierte Benzoylureido-o-benzoylamide, Verfahren zu deren Herstellung und deren Verwendung
US7169926B1 (en) 2003-08-13 2007-01-30 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
US7678909B1 (en) 2003-08-13 2010-03-16 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
CN1867560A (zh) * 2003-08-13 2006-11-22 武田药品工株式会社 4－嘧啶酮衍生物及其作为肽基肽酶抑制剂的用途
US20060247167A1 (en) * 2003-09-01 2006-11-02 Novo Nordisk A/S Stable formulations of peptides
EP1663295A2 (fr) * 2003-09-01 2006-06-07 Novo Nordisk A/S Formulations de peptides stables
EP1699777B1 (fr) * 2003-09-08 2012-12-12 Takeda Pharmaceutical Company Limited Inhibiteurs de la dipeptidylpeptidase
WO2005030751A2 (fr) * 2003-09-08 2005-04-07 Takeda Pharmaceutical Company Limited Inhibiteurs de dipeptidyle peptidase
CN104826116A (zh) * 2003-11-20 2015-08-12 诺沃挪第克公司 对于生产和用于注射装置中是最佳的含有丙二醇的肽制剂
AR047776A1 (es) * 2003-12-16 2006-02-22 Sod Conseils Rech Applic Composiciones farmaceuticas glp - 1
US20060286129A1 (en) * 2003-12-19 2006-12-21 Emisphere Technologies, Inc. Oral GLP-1 formulations
US7732446B1 (en) 2004-03-11 2010-06-08 Takeda Pharmaceutical Company Limited Dipeptidyl peptidase inhibitors
BRPI0418639B8 (pt) 2004-03-15 2021-05-25 Takeda Pharmaceutical compostos inibidores de dipeptidil peptidase, assim como composição farmacêutica contendo os mesmos
WO2005118555A1 (fr) * 2004-06-04 2005-12-15 Takeda Pharmaceutical Company Limited Inhibiteurs de la dipeptidyl peptidase
WO2006019965A2 (fr) 2004-07-16 2006-02-23 Takeda San Diego, Inc. Inhibiteurs de la dipeptidyl peptidase
DK1786784T3 (da) 2004-08-20 2011-02-14 Mannkind Corp Katalyse af diketopiperazinsyntese
ES2543007T3 (es) 2004-08-23 2015-08-13 Mannkind Corporation Micropartículas que comprenden sales de dicetopiperazina para la administración de fármacos
JP4965446B2 (ja) * 2004-08-31 2012-07-04 ノヴォ ノルディスク アー／エス ペプチド、ポリペプチド及びタンパク質の安定化のためのトリス（ヒドロキシメチル）アミノメタンの使用
ES2458991T3 (es) 2004-11-12 2014-05-07 Novo Nordisk A/S Formulaciones estables de péptidos insulinotrópicos
EP1828192B1 (fr) 2004-12-21 2014-12-03 Takeda Pharmaceutical Company Limited Inhibiteurs de dipeptidyle peptidase
KR20070115947A (ko) 2005-02-11 2007-12-06 아밀린 파마슈티칼스, 인크. 선택가능한 특성들을 가지는 ｇｉｐ 유사체 및 하이브리드폴리펩타이드
AU2006265814B2 (en) * 2005-06-30 2012-05-10 Ipsen Pharma S.A.S. GLP-1 pharmaceutical compositions
US20070004616A1 (en) * 2005-06-30 2007-01-04 Roland Cherif-Cheikh GLP-1 pharmaceutical compositions
PE20070622A1 (es) * 2005-09-14 2007-08-22 Takeda Pharmaceutical Administracion de inhibidores de dipeptidil peptidasa
HRP20140091T4 (hr) * 2005-09-14 2021-12-24 Takeda Pharmaceutical Company Limited Davanje inhibitora dipeptidil peptidaze
NZ566799A (en) 2005-09-14 2011-04-29 Takeda Pharmaceutical Dipeptidyl peptidase inhibitors for treating diabetes
IN2014DN09128A (fr) 2005-09-14 2015-07-10 Mannkind Corp
TW200745079A (en) * 2005-09-16 2007-12-16 Takeda Pharmaceuticals Co Polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile and methods of use therefor
CN101360723A (zh) * 2005-09-16 2009-02-04 武田药品工业株式会社 制备嘧啶二酮衍生物的方法
TW200745080A (en) * 2005-09-16 2007-12-16 Takeda Pharmaceuticals Co Polymorphs of tartrate salt of 2-[2-(3-(R)-amino-piperidin-1-yl)-5-fluoro-6-oxo-6H-pyrimidin-1-ylmethyl]-benzonitrile and methods of use therefor
WO2007102946A2 (fr) * 2006-01-23 2007-09-13 Amgen Inc. Polypeptides cristallins
US8039431B2 (en) 2006-02-22 2011-10-18 Mannkind Corporation Method for improving the pharmaceutic properties of microparticles comprising diketopiperazine and an active agent
WO2007112347A1 (fr) 2006-03-28 2007-10-04 Takeda Pharmaceutical Company Limited Inhibiteurs de la dipeptidyl peptidase
JP2009531456A (ja) * 2006-03-28 2009-09-03 武田薬品工業株式会社 （ｒ）−３−アミノピペリジン二塩酸塩の調製
EP2015769A4 (fr) * 2006-04-13 2013-12-25 Ipsen Pharma Compositions pharmaceutiques de hglp-1, exendine 4 et leurs analogues
PE20121528A1 (es) * 2006-09-13 2012-12-12 Smithkline Beecham Corp Metodos para administrar agentes hipoglucemiantes de larga duracion
EA017799B1 (ru) * 2006-09-13 2013-03-29 Такеда Фармасьютикал Компани Лимитед Применение 2-[6-(3-аминопиперидин-1-ил)-3-метил-2,4-диоксо-3,4-дигидро-2н-пиримидин-1-илметил]-4-фторбензонитрила
US8324383B2 (en) 2006-09-13 2012-12-04 Takeda Pharmaceutical Company Limited Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile
TW200838536A (en) * 2006-11-29 2008-10-01 Takeda Pharmaceutical Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor
US8093236B2 (en) 2007-03-13 2012-01-10 Takeda Pharmaceuticals Company Limited Weekly administration of dipeptidyl peptidase inhibitors
BRPI0818874A2 (pt) * 2007-10-24 2015-05-05 Mannkind Corp Liberação de agentes ativos
US8785396B2 (en) 2007-10-24 2014-07-22 Mannkind Corporation Method and composition for treating migraines
HUE025485T2 (en) * 2007-10-24 2016-02-29 Mannkind Corp Respiratory dry powder formulation containing GLP-1 for use in the treatment of hyperglycemia and diabetes by pulmonary administration
EP3281663B8 (fr) 2008-06-13 2022-09-21 MannKind Corporation Inhalateur de poudre sèche alimenté par la respiration pour l'administration de médicaments
US8485180B2 (en) 2008-06-13 2013-07-16 Mannkind Corporation Dry powder drug delivery system
WO2009155581A1 (fr) 2008-06-20 2009-12-23 Mannkind Corporation Appareil interactif pour l’établissement en temps réel d’un profil des efforts d’inhalation
TWI614024B (zh) 2008-08-11 2018-02-11 曼凱公司 超快起作用胰島素之用途
PT2373681T (pt) 2008-12-10 2017-04-11 Glaxosmithkline Llc Composições farmacêuticas de albiglutida
US8314106B2 (en) 2008-12-29 2012-11-20 Mannkind Corporation Substituted diketopiperazine analogs for use as drug delivery agents
JP5918539B2 (ja) 2009-01-08 2016-05-18 マンカインド コーポレイション Ｇｌｐ−１を用いる高血糖症の治療方法
EP2216042A1 (fr) 2009-02-09 2010-08-11 Ipsen Pharma S.A.S. Compositions pharmaceutiques analogues au GLP-1
DK2405963T3 (da) 2009-03-11 2013-12-16 Mannkind Corp Apparat, system og fremgangsmåde til at måle modstand i en inhalator
WO2010144789A2 (fr) 2009-06-12 2010-12-16 Mannkind Corporation Microparticules de dicétopipérazine avec des surfaces spécifiques définies
EP2482840A4 (fr) * 2009-08-07 2013-06-26 Mannkind Corp Composition glp-1 val (8) et procédé de traitement de la dyspepsie fonctionnelle et/ou du syndrome du côlon irritable
WO2011056889A1 (fr) 2009-11-03 2011-05-12 Mannkind Corporation Appareil et méthode de simulation d'efforts d'inhalation
US8691763B2 (en) 2010-05-04 2014-04-08 Glaxosmithkline Llc Methods for treating or preventing cardiovascular disorders and providing cardiovascular protection
JP6385673B2 (ja) 2010-06-21 2018-09-05 マンカインド コーポレイション 乾燥粉末薬物送達システム
EP2600887A4 (fr) 2010-07-09 2014-01-22 Amylin Pharmaceuticals Llc Agonistes microcristallins des récepteurs y
DK2694402T3 (en) 2011-04-01 2017-07-03 Mannkind Corp BLISTER PACKAGE FOR PHARMACEUTICAL CYLINDER AMPULS
WO2012174472A1 (fr) 2011-06-17 2012-12-20 Mannkind Corporation Microparticules de dicétopipérazine de capacité élevée
BR112014009686A2 (pt) 2011-10-24 2018-08-07 Mannkind Corp composição analgésica inalável, pó seco e método para tratar dor
MX354163B (es) 2012-07-12 2018-02-15 Mannkind Corp Sistemas y métodos de suministro de fármaco en polvo seco.
EP2911690A1 (fr) 2012-10-26 2015-09-02 MannKind Corporation Compositions et procédés de vaccin antigrippal inhalable
KR102391750B1 (ko) 2013-03-15 2022-04-28 맨카인드 코포레이션 미세결정성 디케토피페라진 조성물 및 방법
CN110038118A (zh) * 2013-04-16 2019-07-23 石药集团百克(山东)生物制药有限公司 重组胰高血糖素样肽-1受体激动剂的注射用药物组合物
MX2016000739A (es) 2013-07-18 2017-04-06 Mannkind Corp Composiciones farmacéuticas en polvo seco estables al calor y métodos.
EP3030294B1 (fr) 2013-08-05 2020-10-07 MannKind Corporation Appareil d'insufflation
AR100306A1 (es) 2014-02-18 2016-09-28 Novo Nordisk As Análogos de glucagón estables y uso para el tratamiento de la hipoglucemia
WO2015148905A1 (fr) 2014-03-28 2015-10-01 Mannkind Corporation Utilisation d'insuline à action ultrarapide
US10561806B2 (en) 2014-10-02 2020-02-18 Mannkind Corporation Mouthpiece cover for an inhaler
CN111050750A (zh) 2017-08-24 2020-04-21 诺沃挪第克公司 Glp-1组合物及其用途
CN108042794B (zh) * 2018-01-05 2022-01-25 北京博康健基因科技有限公司 重组促胰岛素分泌素的稳定制剂及其制备方法
KR20220143036A (ko) 2020-02-18 2022-10-24 노보 노르디스크 에이/에스 약학적 제형

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120712A (en) 1986-05-05 1992-06-09 The General Hospital Corporation Insulinotropic hormone
US5118666A (en) 1986-05-05 1992-06-02 The General Hospital Corporation Insulinotropic hormone
US5545618A (en) 1990-01-24 1996-08-13 Buckley; Douglas I. GLP-1 analogs useful for diabetes treatment
US5780599A (en) * 1990-07-13 1998-07-14 Novo Nordisk A/S Growth hormone crystals and a process for production of growth hormone crystals
CZ315594A3 (en) 1992-06-15 1995-07-12 Pfizer Peptide of glucagon type, insulinotropic derivatives, process of their preparation, pharmaceutical composition containing such compounds and use
SE9302278D0 (sv) * 1992-10-28 1993-07-02 Kabi Pharmacia Ab Growth hormone
US6284727B1 (en) * 1993-04-07 2001-09-04 Scios, Inc. Prolonged delivery of peptides
HU225496B1 (en) 1993-04-07 2007-01-29 Scios Inc Pharmaceutical compositions of prolonged delivery, containing peptides
AU7531094A (en) 1993-08-24 1995-03-21 Novo Nordisk A/S Protracted glp-1
US5705483A (en) * 1993-12-09 1998-01-06 Eli Lilly And Company Glucagon-like insulinotropic peptides, compositions and methods
EP0658568A1 (fr) * 1993-12-09 1995-06-21 Eli Lilly And Company Peptides insulinotropes de type glucagon, compositions les contenant et méthode de préparation
US5512549A (en) 1994-10-18 1996-04-30 Eli Lilly And Company Glucagon-like insulinotropic peptide analogs, compositions, and methods of use
EP0796106B1 (fr) 1994-12-23 2003-03-19 Novo Nordisk A/S Compositions a base de glp-1 et a action prolongee
US5766620A (en) 1995-10-23 1998-06-16 Theratech, Inc. Buccal delivery of glucagon-like insulinotropic peptides
ATE356830T1 (de) 1996-08-30 2007-04-15 Novo Nordisk As Glp-1 derivate
UA65549C2 (uk) 1996-11-05 2004-04-15 Елі Ліллі Енд Компані Спосіб регулювання ожиріння шляхом периферійного введення аналогів та похідних glp-1 (варіанти) та фармацевтична композиція
ATE366584T1 (de) 1996-11-12 2007-08-15 Novo Nordisk As Verwendung von glp-1 peptiden
CA2283834A1 (fr) 1997-03-31 1998-10-08 James Arthur Hoffmann Analogues de peptide 1 assimile au glucagon (glp-1)
US6380357B2 (en) * 1997-12-16 2002-04-30 Eli Lilly And Company Glucagon-like peptide-1 crystals

Also Published As

Publication number Publication date
EP0926159A2 (fr) 1999-06-30
US6555521B2 (en) 2003-04-29
IL136377A0 (en) 2001-06-14
TR200001726T2 (tr) 2000-10-23
CZ20002104A3 (cs) 2001-08-15
HRP20000409A2 (en) 2000-10-31
US20030045464A1 (en) 2003-03-06
NO20003081D0 (no) 2000-06-15
NZ505182A (en) 2002-05-31
NO20003081L (no) 2000-08-08
AU1821899A (en) 1999-07-05
SV1998000147A (es) 1999-08-18
WO1999030731A1 (fr) 1999-06-24
US20010014666A1 (en) 2001-08-16
USRE41133E1 (en) 2010-02-16
EP0926159A3 (fr) 2003-11-26
PL341210A1 (en) 2001-03-26
EA200000652A1 (ru) 2000-12-25
US6380357B2 (en) 2002-04-30
PE20000059A1 (es) 2000-02-09
CO5040043A1 (es) 2001-05-29
CN1281369A (zh) 2001-01-24
BR9813658A (pt) 2000-10-10
JP2002508332A (ja) 2002-03-19
ZA9811466B (en) 2000-06-14
AR019806A1 (es) 2002-03-20
KR20010033146A (ko) 2001-04-25
CA2315243A1 (fr) 1999-06-24
HUP0100046A2 (hu) 2001-05-28

Similar Documents

Publication Publication Date Title
ID25534A (id) Glucagon-seperti kristal peptida-1
ID25660A (id) Teripatide kristal
DE69826244D1 (de) Programmierbarer kristalloszillator
DE69822774D1 (de) Armbanduhr
DE69738993D1 (de) Flüssigkristallanzeige
DE69708981T2 (de) Flüssigkristallanzeige
DE69710512T2 (de) Flüssigkristallanzeige
DE69840837D1 (de) Flüssigkristallanzeige
PT1021439E (pt) Polimorfo antifungico cristalino
TR199801513A3 (tr) N-(4-Triflormetilfenil)- 5- metil-izoksazol-4-karboksamidin kristal formu.
DE69839563D1 (de) Kohlenhydrat-vernetzte glykoproteinkristalle
ID19914A (id) Kacamata
KR970705775A (ko) 강유전성 액정 장치(Ferroeletric loquid crystal devices)
DE69531247D1 (de) Orientierte kristallanordnung
DE69800559T2 (de) Ferrielektrische Flüssigkristallverbindung
DE69710146T2 (de) Kristallhaltevorrichtung
DE69823908D1 (de) Einkristallziehvorrichtung
DE69935146D1 (de) Nichtlinearer optischer kristall
DE29707964U1 (de) Hintergrundleuchte
ID27596A (id) Bentuk paroksetina kristal
DE69508469D1 (de) Oxyde-Granat-Einkristall
DE69920662D1 (de) Sibe-kristall
DE29707135U1 (de) Brillenbügel
ATA182397A (de) Armbanduhr
KR950025617U (ko) 액정표시소자