HUT77361A - 1,2-Etándiol-származékot vagy sóját tartalmazó gyógyszerkészítmény ideg növekedési faktor (NFG) aktivitás potenciálására - Google Patents

1,2-Etándiol-származékot vagy sóját tartalmazó gyógyszerkészítmény ideg növekedési faktor (NFG) aktivitás potenciálására

Info

Publication number
HUT77361A
HUT77361A HU9701903A HU9701903A HUT77361A HU T77361 A HUT77361 A HU T77361A HU 9701903 A HU9701903 A HU 9701903A HU 9701903 A HU9701903 A HU 9701903A HU T77361 A HUT77361 A HU T77361A
Authority
HU
Hungary
Prior art keywords
salt
pharmaceutical composition
growth factor
nerve growth
factor containing
Prior art date
Application number
HU9701903A
Other languages
English (en)
Other versions
HU226980B1 (en
Inventor
Kazunari Hirata
Mutsuko Maekawa
Hirokazu Narita
Satoshi Ono
Original Assignee
Toyama Chemical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP6284273A external-priority patent/JPH08268883A/ja
Application filed by Toyama Chemical Co., Ltd. filed Critical Toyama Chemical Co., Ltd.
Publication of HUT77361A publication Critical patent/HUT77361A/hu
Publication of HU226980B1 publication Critical patent/HU226980B1/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/02Drugs for disorders of the nervous system for peripheral neuropathies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/06Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted
    • C07C217/08Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom
    • C07C217/10Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having only one etherified hydroxy group and one amino group bound to the carbon skeleton, which is not further substituted the oxygen atom of the etherified hydroxy group being further bound to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/54Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D453/00Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08Bridged systems
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
HU9701903A 1994-10-25 1995-10-20 Use of 1,2-ethanediol derivatives or salts thereof for the preparation of pharmaceutical compositions having nerve growth factor (nfg) potentiator activity HU226980B1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP6284273A JPH08268883A (ja) 1994-10-25 1994-10-25 1−フェニル−1,2−エタンジオール誘導体またはそ の塩を含有する神経成長因子の作用増強剤
JP28427294 1994-10-25
PCT/JP1995/002162 WO1996012717A1 (fr) 1994-10-25 1995-10-20 Potentialisateur de l'activite du facteur de croissance nerveuse contenant un derive de 1,2-ethanediol ou un sel de celui-ci

Publications (2)

Publication Number Publication Date
HUT77361A true HUT77361A (hu) 1998-03-30
HU226980B1 HU226980B1 (en) 2010-04-28

Family

ID=26555404

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9701903A HU226980B1 (en) 1994-10-25 1995-10-20 Use of 1,2-ethanediol derivatives or salts thereof for the preparation of pharmaceutical compositions having nerve growth factor (nfg) potentiator activity

Country Status (16)

Country Link
US (6) US5807887A (hu)
EP (3) EP0790246B1 (hu)
JP (1) JP3218247B2 (hu)
KR (1) KR100447738B1 (hu)
AU (1) AU700561B2 (hu)
CA (1) CA2202032C (hu)
CZ (1) CZ293528B6 (hu)
DE (2) DE69531877T2 (hu)
DK (2) DK1020427T3 (hu)
ES (2) ES2208156T3 (hu)
HU (1) HU226980B1 (hu)
NZ (1) NZ294328A (hu)
PL (2) PL187004B1 (hu)
RO (1) RO119196B1 (hu)
TW (1) TW341570B (hu)
WO (1) WO1996012717A1 (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100447738B1 (ko) * 1994-10-25 2005-09-20 도야마 가가쿠 고교 가부시키가이샤 1,2-에탄디올유도체또는그의염을함유한의약조성물
ZA973394B (en) * 1996-04-22 1997-11-20 Toyama Chemical Co Ltd Plaster containing 1,2-ethanediol derivative or a salt thereof.
AU1506499A (en) * 1997-12-12 1999-07-05 Toyama Chemical Co. Ltd. Alkyl ether derivatives or salts thereof and calcium antagonists containing the same
JP4549452B2 (ja) * 1997-12-12 2010-09-22 富山化学工業株式会社 アルキルエーテル誘導体またはその塩並びにそれらを含有するカルシウム拮抗剤
DK1186594T3 (da) * 1999-06-11 2009-09-14 Toyama Chemical Co Ltd N-alkoxylkyl-N,N-dialkylamin-derivater eller salte deraf og midler mod neurodegenerative sygdomme, som indeholder disse
AU9235101A (en) * 2000-10-10 2002-04-22 Toyama Chemical Co Ltd Remedies for retinal nerve diseases containing 1,2-ethanediol derivatives or salts thereof
HU230407B1 (hu) 2001-10-19 2016-04-28 Toyama Chemical Co., Ltd. Alkil-éter-származékok és sóik
MXPA04012534A (es) 2002-06-14 2005-04-19 Toyama Chemical Co Ltd Composicion farmaceutica para mejorar la funcion cerebral y metodo para mejorar la funcion cerebral.
EP2248899B8 (en) 2003-03-19 2015-07-15 Biogen MA Inc. NOGO receptor binding protein
US8486893B2 (en) 2004-06-24 2013-07-16 Biogen Idec Ma Inc. Treatment of conditions involving demyelination
EP1904104B1 (en) 2005-07-08 2013-09-11 Biogen Idec MA Inc. Sp35 antibodies and uses thereof
JP2009544703A (ja) 2006-07-24 2009-12-17 バイオジェン・アイデック・エムエイ・インコーポレイテッド Sp35またはTrkAアンタゴニストの投与により髄鞘形成、ニューロンの生存および希乏突起膠細胞の分化を促進するための方法
JP5674469B2 (ja) * 2007-10-11 2015-02-25 バイオジェン・アイデック・エムエイ・インコーポレイテッド LINGO−1アンタゴニストおよびTrkBアゴニストの投与を介して圧力誘導性の視神経障害を処置し、神経変性を防ぎ、ニューロン細胞の生存を促進する方法
US20110123553A1 (en) * 2007-11-08 2011-05-26 Biogen Idec Ma Inc. Use of LINGO-4 Antagonists in the Treatment of Conditions Involving Demyelination
AU2009269099B2 (en) 2008-07-09 2016-03-10 Biogen Ma Inc. Compositions comprising antibodies to LINGO or fragments thereof
NZ702178A (en) 2012-05-14 2017-01-27 Biogen Ma Inc Lingo-2 antagonists for treatment of conditions involving motor neurons
EP3242893A1 (en) 2015-01-08 2017-11-15 Biogen MA Inc. Lingo-1 antagonists and uses for treatment of demyelinating disorders

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3894058A (en) * 1974-05-17 1975-07-08 Hoechst Co American Tetrahydrobenzofuranylphenoxypropylamines
US5254595A (en) * 1988-12-23 1993-10-19 Elf Sanofi Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them
NZ232493A (en) * 1989-02-14 1992-06-25 Toyama Chemical Co Ltd Aryl- or heterocyclyl-substituted 1,2-ethanediol derivatives and pharmaceutical compositions
US5280032A (en) * 1989-02-14 1994-01-18 Toyama Chemical Co., Ltd. 1,2-ethanediol derivative and salt thereof, process for producing the same, and cerebral function-improving agent comprising the same
JP3044055B2 (ja) * 1990-08-09 2000-05-22 富山化学工業株式会社 1,2―エタンジオール誘導体およびその塩
JPH05230103A (ja) * 1992-02-18 1993-09-07 Taisho Pharmaceut Co Ltd ガングリオシド化合物
KR100447738B1 (ko) * 1994-10-25 2005-09-20 도야마 가가쿠 고교 가부시키가이샤 1,2-에탄디올유도체또는그의염을함유한의약조성물

Also Published As

Publication number Publication date
PL187490B1 (pl) 2004-07-30
RO119196B1 (ro) 2004-05-28
DE69525063D1 (de) 2002-02-21
AU700561B2 (en) 1999-01-07
US5968935A (en) 1999-10-19
US6034119A (en) 2000-03-07
WO1996012717A1 (fr) 1996-05-02
ES2208156T3 (es) 2004-06-16
EP0790246A4 (en) 1998-03-11
US5922721A (en) 1999-07-13
TW341570B (en) 1998-10-01
DK0790246T3 (da) 2002-03-18
CA2202032A1 (en) 1996-05-02
KR970707114A (ko) 1997-12-01
KR100447738B1 (ko) 2005-09-20
EP1020427A1 (en) 2000-07-19
US6103754A (en) 2000-08-15
PL187004B1 (pl) 2004-04-30
EP0790246A1 (en) 1997-08-20
US5932620A (en) 1999-08-03
ES2171559T3 (es) 2002-09-16
US5807887A (en) 1998-09-15
CZ293528B6 (cs) 2004-05-12
AU3709795A (en) 1996-05-15
DK1020427T3 (da) 2004-02-09
CA2202032C (en) 2009-06-16
DE69525063T2 (de) 2002-08-14
EP1020427B1 (en) 2003-10-01
DE69531877D1 (de) 2003-11-06
DE69531877T2 (de) 2004-07-29
CZ124997A3 (en) 1997-10-15
NZ294328A (en) 1998-06-26
EP1223169A1 (en) 2002-07-17
JP3218247B2 (ja) 2001-10-15
PL319940A1 (en) 1997-09-01
HU226980B1 (en) 2010-04-28
EP0790246B1 (en) 2002-01-16

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Legal Events

Date Code Title Description
MM4A Lapse of definitive patent protection due to non-payment of fees