HUT65910A - Process for preparing oxygen containing macrocyclic organic compounds - Google Patents

Process for preparing oxygen containing macrocyclic organic compounds Download PDF

Info

Publication number
HUT65910A
HUT65910A HU9303444A HU9303444A HUT65910A HU T65910 A HUT65910 A HU T65910A HU 9303444 A HU9303444 A HU 9303444A HU 9303444 A HU9303444 A HU 9303444A HU T65910 A HUT65910 A HU T65910A
Authority
HU
Hungary
Prior art keywords
formula
hydrogen
compound
methoxy
hydroxy
Prior art date
Application number
HU9303444A
Other languages
English (en)
Hungarian (hu)
Other versions
HU9303444D0 (en
Inventor
Michael Morris Dreyfuss
Joerg Schnyder
Henri Mattes
Andrew Roland Mackenzie
Rene Paul Traber
Albert Leutwiler
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HU9303444D0 publication Critical patent/HU9303444D0/hu
Publication of HUT65910A publication Critical patent/HUT65910A/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D313/00Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungal isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02Oxygen as only ring hetero atoms
    • C12P17/08Oxygen as only ring hetero atoms containing a hetero ring of at least seven ring members, e.g. zearalenone, macrolide aglycons
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Botany (AREA)
  • Vascular Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Dermatology (AREA)
  • Mycology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pyrane Compounds (AREA)
HU9303444A 1992-12-04 1993-12-03 Process for preparing oxygen containing macrocyclic organic compounds HUT65910A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB929225396A GB9225396D0 (en) 1992-12-04 1992-12-04 Improvements in or relating to organic compounds

Publications (2)

Publication Number Publication Date
HU9303444D0 HU9303444D0 (en) 1994-04-28
HUT65910A true HUT65910A (en) 1994-07-28

Family

ID=10726140

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9303444A HUT65910A (en) 1992-12-04 1993-12-03 Process for preparing oxygen containing macrocyclic organic compounds

Country Status (18)

Country Link
EP (1) EP0606044A1 (fi)
JP (1) JPH06228122A (fi)
KR (1) KR940014377A (fi)
CN (1) CN1095417A (fi)
AU (1) AU5211293A (fi)
CA (1) CA2110553A1 (fi)
CZ (1) CZ261493A3 (fi)
FI (1) FI935409A (fi)
GB (1) GB9225396D0 (fi)
HU (1) HUT65910A (fi)
IL (1) IL107838A0 (fi)
MX (1) MX9307608A (fi)
NO (1) NO934372L (fi)
NZ (1) NZ250344A (fi)
PL (1) PL301281A1 (fi)
SK (1) SK135493A3 (fi)
TW (1) TW258736B (fi)
ZA (1) ZA939088B (fi)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4228328C2 (de) * 1992-08-26 1999-02-11 Agie Sa Maschine und Verfahren zum funkenerosiven Drahtschneiden mit einer im Querschnitt verformten Drahtelektrode
US5795910A (en) * 1994-10-28 1998-08-18 Cor Therapeutics, Inc. Method and compositions for inhibiting protein kinases
US5731343A (en) * 1995-02-24 1998-03-24 The Scripps Research Institute Method of use of radicicol for treatment of immunopathological disorders
EP0823429B1 (en) * 1995-04-26 2000-07-12 Kyowa Hakko Kogyo Co., Ltd. Radicicol derivatives
AU779438B2 (en) * 1998-12-24 2005-01-27 Novation Pharmaceuticals Inc. Compounds which affect mRNA stability and uses therefor
ATE328888T1 (de) 2000-08-25 2006-06-15 Sloan Kettering Inst Cancer Radicicol und monocillin und ihre analogen und ihre anwendungen
JP2004292314A (ja) * 2000-12-14 2004-10-21 Chugai Pharmaceut Co Ltd ケラチノサイト増殖抑制剤
JP2004292315A (ja) * 2000-12-14 2004-10-21 Chugai Pharmaceut Co Ltd Tak1阻害剤
GB0112522D0 (en) * 2001-05-23 2001-07-11 Ici Plc Catalytic process
PL221491B1 (pl) 2002-03-08 2016-04-29 Eisai R&D Man Co Związki makrocykliczne, środek farmaceutyczny zawierający te związki oraz zastosowanie tych związków
US7915306B2 (en) * 2002-03-08 2011-03-29 Eisai Co., Ltd. Macrocyclic compounds useful as pharmaceuticals
CA2482940A1 (en) * 2002-04-17 2003-10-23 Taisho Pharmaceuticals Co., Ltd. Hair growth tonic
WO2006036941A2 (en) * 2004-09-27 2006-04-06 Kosan Biosciences Incorporated Specific kinase inhibitors
US7601852B2 (en) 2006-05-11 2009-10-13 Kosan Biosciences Incorporated Macrocyclic kinase inhibitors
JP5484327B2 (ja) 2007-07-25 2014-05-07 エーザイ・アール・アンド・ディー・マネジメント株式会社 癌の処置において使用するための多キナーゼインヒビター
EP2215471B1 (en) 2007-10-29 2012-02-08 Eisai R&D Management Co., Ltd. Methods for prognosing the ability of a zearalenone analog compound to treat cancer
WO2009075823A1 (en) 2007-12-07 2009-06-18 Eisai R & D Management Co., Ltd. Intermediates in the synthesis of zearalenone macrolide analogs
WO2010045342A1 (en) 2008-10-17 2010-04-22 Wisconsin Alumni Research Foundation Method of making biologically active alpha-beta peptides

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3196019A (en) * 1964-04-06 1965-07-20 Purdue Research Foundation Anabolic and estrogenic compound and process of making

Also Published As

Publication number Publication date
EP0606044A1 (en) 1994-07-13
IL107838A0 (en) 1994-04-12
NO934372D0 (no) 1993-12-02
CZ261493A3 (en) 1994-07-13
KR940014377A (ko) 1994-07-18
GB9225396D0 (en) 1993-01-27
NZ250344A (en) 1995-10-26
PL301281A1 (en) 1994-06-13
CN1095417A (zh) 1994-11-23
NO934372L (no) 1994-06-06
JPH06228122A (ja) 1994-08-16
TW258736B (fi) 1995-10-01
MX9307608A (es) 1995-01-31
AU5211293A (en) 1994-06-16
ZA939088B (en) 1995-06-05
FI935409A (fi) 1994-06-05
CA2110553A1 (en) 1994-06-05
FI935409A0 (fi) 1993-12-02
SK135493A3 (en) 1994-08-10
HU9303444D0 (en) 1994-04-28

Similar Documents

Publication Publication Date Title
HUT65910A (en) Process for preparing oxygen containing macrocyclic organic compounds
US6596518B2 (en) Percyquinnin, a process for its production and its use as a pharmaceutical
US5468773A (en) Methods for inhibiting bone loss and cartilage degradation using wortmannin and its analogs
DK149095B (da) Fremgangsmaade til fremstilling af en cholesterolsynteseinhiberende forbindelse kaldet monacolin k
BG100699A (bg) Карбоциклични съединения
US20060167080A1 (en) Wortmannin analogs and methods of using same
US6365610B1 (en) Ozonide compounds with inhibitory activity for urokinase production and angiogenesis
EP1318991A1 (en) Benzoic acid derivatives and uses thereof
RU2171260C2 (ru) Циклопептолиды
KR20020037730A (ko) 해양 방선균류로부터 분리된 신규한 인돌로카바졸알칼로이드
AU665488B2 (en) New compound, leustroducsin H, its preparation and its therapeutic use
US6380257B1 (en) Aromatic di-keto derivatives, processes for their production and their use as a pharmaceutical
CZ20032426A3 (cs) Deriváty caloporosidu, léčiva s jejich obsahem, způsob přípravy těchto látek pomocí mikroorganismu a tento mikroorganismus
JP3942422B2 (ja) 抗腫瘍・抗炎症作用を有する新規物質
KR100322240B1 (ko) 페니실리움 속(Penicillium sp.)F70614(KCTC 8918P)와 α-글루코시다제 저해제
JP4452787B2 (ja) 新規発酵生産物
KR100321844B1 (ko) 4'-오-데메틸-에피포도필로톡신-베타-디-글루코시드의새로운아세탈유도체,이의제조방법및이를포함하는항암제조성물
JPH09286779A (ja) 新規化合物レブラスタチン
WO1996026956A1 (en) Protein phosphatase inhibitor
JPS62270527A (ja) 4181−2物質及びその誘導体を有効成分とする抗腫瘍剤
JPH08507551A (ja) 抗腫瘍剤としての3−(7−オキソ−1−アザ−4−オキサビシクロ[3.2.0]ヘプト−3−イル)アラニン誘導体
JPH1017527A (ja) 抗菌性物質be−39589類及びその製造法
JPH10147551A (ja) ヒドロナフタレン誘導体を有効成分とする抗炎症剤、抗癌剤及び新規ヒドロナフタレン誘導体
JPH07258242A (ja) 抗腫瘍性物質be−39891類

Legal Events

Date Code Title Description
DFA9 Temporary protection cancelled due to abandonment