HUT63858A - Process for producing new insulin complexes - Google Patents

Process for producing new insulin complexes Download PDF

Info

Publication number
HUT63858A
HUT63858A HU922721Q HU272191Q HUT63858A HU T63858 A HUT63858 A HU T63858A HU 922721 Q HU922721 Q HU 922721Q HU 272191 Q HU272191 Q HU 272191Q HU T63858 A HUT63858 A HU T63858A
Authority
HU
Hungary
Prior art keywords
insulin
iii
cobalt
mixture
water
Prior art date
Application number
HU922721Q
Other languages
English (en)
Hungarian (hu)
Other versions
HU9202721D0 (en
Inventor
Jorgen Frederik Hansen
Ulla Ribel-Madsen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of HU9202721D0 publication Critical patent/HU9202721D0/hu
Publication of HUT63858A publication Critical patent/HUT63858A/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/28—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/52—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an inorganic compound, e.g. an inorganic ion that is complexed with the active ingredient
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Chairs For Special Purposes, Such As Reclining Chairs (AREA)
  • Medicinal Preparation (AREA)
HU922721Q 1990-02-21 1991-02-21 Process for producing new insulin complexes HUT63858A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK045590A DK45590D0 (OSRAM) 1990-02-21 1990-02-21

Publications (2)

Publication Number Publication Date
HU9202721D0 HU9202721D0 (en) 1992-12-28
HUT63858A true HUT63858A (en) 1993-10-28

Family

ID=8093754

Family Applications (1)

Application Number Title Priority Date Filing Date
HU922721Q HUT63858A (en) 1990-02-21 1991-02-21 Process for producing new insulin complexes

Country Status (12)

Country Link
EP (1) EP0516704B1 (OSRAM)
JP (1) JPH05503940A (OSRAM)
AU (1) AU641991B2 (OSRAM)
CA (1) CA2075982A1 (OSRAM)
DE (1) DE69100626D1 (OSRAM)
DK (1) DK45590D0 (OSRAM)
HU (1) HUT63858A (OSRAM)
IE (1) IE910579A1 (OSRAM)
NZ (1) NZ237176A (OSRAM)
PT (1) PT96841A (OSRAM)
WO (1) WO1991012817A1 (OSRAM)
ZA (1) ZA911279B (OSRAM)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9316895D0 (en) * 1993-08-13 1993-09-29 Guy S And St Thomas Hospitals Hepatoselective insulin analogues
US6342225B1 (en) 1993-08-13 2002-01-29 Deutshces Wollforschungsinstitut Pharmaceutical active conjugates
US6011007A (en) * 1993-09-17 2000-01-04 Novo Nordisk A/S Acylated insulin
US6869930B1 (en) 1993-09-17 2005-03-22 Novo Nordisk A/S Acylated insulin
DE122004000035I2 (de) * 1993-09-17 2009-08-06 Novo Nordisk As Acyliertes insulin
US6251856B1 (en) 1995-03-17 2001-06-26 Novo Nordisk A/S Insulin derivatives
US6451762B1 (en) 1997-10-24 2002-09-17 Novo Nordisk A/S Aggregates of human insulin derivatives
EP2107069B1 (en) 2003-08-05 2013-01-16 Novo Nordisk A/S Novel insulin derivatives
PT2107069E (pt) 2003-08-05 2013-04-23 Novo Nordisk As Novos derivados de insulina
EP2256130B1 (en) 2005-02-02 2013-09-25 Novo Nordisk A/S Novel insulin derivatives
EP2505593A1 (en) 2005-12-28 2012-10-03 Novo Nordisk A/S Compositions comprising an acylated insulin and zinc and method of making the said compositions
JP5550338B2 (ja) 2006-07-31 2014-07-16 ノボ・ノルデイスク・エー／エス ペグ化持続型インスリン
EP2074141B1 (en) 2006-09-22 2016-08-10 Novo Nordisk A/S Protease resistant insulin analogues
WO2008132224A2 (en) 2007-04-30 2008-11-06 Novo Nordisk A/S Method for drying a protein composition, a dried protein composition and a pharmaceutical composition comprising the dried protein
CN101677947B (zh) 2007-06-13 2013-07-17 诺沃-诺迪斯克有限公司 包含胰岛素衍生物的药物制剂
CN101970477B (zh) 2008-03-14 2014-12-31 诺沃-诺迪斯克有限公司 蛋白酶稳定的胰岛素类似物
PT2910570T (pt) 2008-03-18 2017-01-24 Novo Nordisk As Análogos de insulina acilados, estabilizados contra proteases
AU2009309623B9 (en) 2008-10-30 2014-10-02 Novo Nordisk A/S Treating diabetes melitus using insulin injections with less than daily injection frequency
RU2013123515A (ru) 2010-10-27 2014-12-10 Ново Нордиск А/С Лечение сахарного диабета с помощью инъекций инсулина, вводимых с различными интервалами
BR112014025132A2 (pt) 2012-04-11 2017-07-11 Novo Nordisk As formulações de insulina
WO2014177623A1 (en) 2013-04-30 2014-11-06 Novo Nordisk A/S Novel administration regime
PT3055325T (pt) 2013-10-07 2018-04-06 Novo Nordisk As Novo derivado de um análogo de insulina
PT3554534T (pt) 2016-12-16 2021-11-05 Novo Nordisk As Composições farmacêuticas contendo insulina
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin
US12343383B2 (en) 2019-07-12 2025-07-01 Novo Nordisk A/S High concentration insulin formulation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE971500C (de) * 1950-11-22 1959-02-05 Organon Nv Verfahren zur Herstellung von Insulin-Suspensionen mit verlaengerter Wirkung
DE1107374B (de) * 1958-01-31 1961-05-25 Organon Nv Verfahren zur Herstellung eines Insulin-Praeparates

Also Published As

Publication number Publication date
CA2075982A1 (en) 1991-08-22
EP0516704B1 (en) 1993-11-10
WO1991012817A1 (en) 1991-09-05
IE910579A1 (en) 1991-08-28
DE69100626D1 (de) 1993-12-16
ZA911279B (en) 1991-10-30
PT96841A (pt) 1991-11-29
EP0516704A1 (en) 1992-12-09
DK45590D0 (OSRAM) 1990-02-21
AU641991B2 (en) 1993-10-07
JPH05503940A (ja) 1993-06-24
HU9202721D0 (en) 1992-12-28
NZ237176A (en) 1991-12-23
AU7337891A (en) 1991-09-18

Similar Documents

Publication Publication Date Title
HUT63858A (en) Process for producing new insulin complexes
DE69429169T2 (de) Pharmazeutisches präparat, das heparin, heparinfragmente oder -derivate in kombination mit glycerinestern enthält
US4877778A (en) Method of enhancing lipophile transport using cyclodextrin derivatives
DE3880346T2 (de) Insulinderivate.
DE69815877T2 (de) Aggregate von menschlichen insulinderivaten
KR890004687B1 (ko) 생물학적 활성 서방출성 조성물
JP2004500423A (ja) 徐放製剤
HUT67853A (en) Insulin formulation
AU2001259111A1 (en) Sustained release formulations comprising growth hormone
EP3554534B1 (en) Insulin containing pharmaceutical compositions
JP2002500196A (ja) 安定化させたインスリン組成物
CN1556712A (zh) 含dds化合物的药用组合物
CA1335924C (en) Mixed crystals of insulin and insulin derivatives, a process for the preparation of these mixed crystals, pharmaceutical agents containing these mixed crystals, and the use thereof for the treatment of diabetes mellitus
CS114290A3 (en) Specifically glycosylated insulin derivatives
EP3630166B1 (en) Rapid-acting insulin compositions
EP1620072B1 (en) Zinc-containing sustained-release composition, its preparation, and method for producing the same
EP3834818B1 (en) Stable infusion solution composition containing sugar and amino acid
JP2716497B2 (ja) ヘモグロビン コンプレツクス
EP3996679A1 (en) High concentration insulin formulation
JPH09124512A (ja) 肝臓ターゲティングのための水溶性の薬物−プルラン結合体製剤
JPH0363299A (ja) 修飾エリスロポエチン
HK40016003B (en) Rapid-acting insulin compositions
JPS61251627A (ja) 非経口的投与のための水分散性および水溶性のポリマ−組成物
HRP930063A2 (en) Novel compositions containing hyaluronic acid associates and a process for preparing the same

Legal Events

Date Code Title Description
DFC9 Refusal of application