HUT58796A - Process for producing acetylized heterologue polypeptides - Google Patents

Process for producing acetylized heterologue polypeptides Download PDF

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Publication number
HUT58796A
HUT58796A HU903721A HU372190A HUT58796A HU T58796 A HUT58796 A HU T58796A HU 903721 A HU903721 A HU 903721A HU 372190 A HU372190 A HU 372190A HU T58796 A HUT58796 A HU T58796A
Authority
HU
Hungary
Prior art keywords
rbst
somatotropin
lysine
positions
fermentation
Prior art date
Application number
HU903721A
Other languages
English (en)
Hungarian (hu)
Other versions
HU903721D0 (en
Inventor
David Paul Brunner
Robert Lee Garlick
Gary Clyde Harbour
Stephen Baker Lyle
John Edward Mott
Jules A Shafer
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of HU903721D0 publication Critical patent/HU903721D0/hu
Publication of HUT58796A publication Critical patent/HUT58796A/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
HU903721A 1989-03-15 1990-01-23 Process for producing acetylized heterologue polypeptides HUT58796A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32390189A 1989-03-15 1989-03-15

Publications (2)

Publication Number Publication Date
HU903721D0 HU903721D0 (en) 1991-12-30
HUT58796A true HUT58796A (en) 1992-03-30

Family

ID=23261207

Family Applications (1)

Application Number Title Priority Date Filing Date
HU903721A HUT58796A (en) 1989-03-15 1990-01-23 Process for producing acetylized heterologue polypeptides

Country Status (11)

Country Link
EP (2) EP0719792A2 (OSRAM)
JP (1) JPH04504060A (OSRAM)
KR (1) KR920700292A (OSRAM)
AT (1) ATE142270T1 (OSRAM)
AU (1) AU629929B2 (OSRAM)
CA (1) CA2045173A1 (OSRAM)
DE (1) DE69028396T2 (OSRAM)
DK (1) DK0463115T3 (OSRAM)
ES (1) ES2091241T3 (OSRAM)
HU (1) HUT58796A (OSRAM)
WO (1) WO1990010706A1 (OSRAM)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140071A (en) * 1994-01-27 2000-10-31 Somatogen, Inc. Proteins with mutations to decrease N-terminal methylation
US7547529B1 (en) * 2000-05-10 2009-06-16 Asubio Pharma Co., Ltd. Methods for reducing the formation of by-products in the production of recombinant polypeptides

Also Published As

Publication number Publication date
AU5406090A (en) 1990-10-09
JPH04504060A (ja) 1992-07-23
HU903721D0 (en) 1991-12-30
EP0463115A1 (en) 1992-01-02
CA2045173A1 (en) 1990-09-16
EP0719792A2 (en) 1996-07-03
EP0463115B1 (en) 1996-09-04
KR920700292A (ko) 1992-02-19
AU629929B2 (en) 1992-10-15
DE69028396T2 (de) 1997-02-13
DE69028396D1 (de) 1996-10-10
EP0719792A3 (OSRAM) 1996-07-24
ES2091241T3 (es) 1996-11-01
ATE142270T1 (de) 1996-09-15
WO1990010706A1 (en) 1990-09-20
DK0463115T3 (OSRAM) 1997-02-17

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DFD9 Temporary protection cancelled due to non-payment of fee