AU629929B2 - Acetylated heterologous polypeptides - Google Patents

Acetylated heterologous polypeptides

Info

Publication number
AU629929B2
AU629929B2 AU54060/90A AU5406090A AU629929B2 AU 629929 B2 AU629929 B2 AU 629929B2 AU 54060/90 A AU54060/90 A AU 54060/90A AU 5406090 A AU5406090 A AU 5406090A AU 629929 B2 AU629929 B2 AU 629929B2
Authority
AU
Australia
Prior art keywords
rbst
somatotropin
replaced
acetylated
arginine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU54060/90A
Other languages
English (en)
Other versions
AU5406090A (en
Inventor
David Paul Brunner
Robert Lee Garlick
Gary Clyde Harbour
Stephen Baker Lyle
John Edward Mott
Jules A. Shafer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AU5406090A publication Critical patent/AU5406090A/en
Application granted granted Critical
Publication of AU629929B2 publication Critical patent/AU629929B2/en
Assigned to PHARMACIA & UPJOHN COMPANY reassignment PHARMACIA & UPJOHN COMPANY Request to Amend Deed and Register Assignors: UPJOHN COMPANY, THE
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Endocrinology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU54060/90A 1989-03-15 1990-01-23 Acetylated heterologous polypeptides Ceased AU629929B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32390189A 1989-03-15 1989-03-15
US323901 1989-03-15

Publications (2)

Publication Number Publication Date
AU5406090A AU5406090A (en) 1990-10-09
AU629929B2 true AU629929B2 (en) 1992-10-15

Family

ID=23261207

Family Applications (1)

Application Number Title Priority Date Filing Date
AU54060/90A Ceased AU629929B2 (en) 1989-03-15 1990-01-23 Acetylated heterologous polypeptides

Country Status (11)

Country Link
EP (2) EP0719792A2 (OSRAM)
JP (1) JPH04504060A (OSRAM)
KR (1) KR920700292A (OSRAM)
AT (1) ATE142270T1 (OSRAM)
AU (1) AU629929B2 (OSRAM)
CA (1) CA2045173A1 (OSRAM)
DE (1) DE69028396T2 (OSRAM)
DK (1) DK0463115T3 (OSRAM)
ES (1) ES2091241T3 (OSRAM)
HU (1) HUT58796A (OSRAM)
WO (1) WO1990010706A1 (OSRAM)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6140071A (en) * 1994-01-27 2000-10-31 Somatogen, Inc. Proteins with mutations to decrease N-terminal methylation
US7547529B1 (en) * 2000-05-10 2009-06-16 Asubio Pharma Co., Ltd. Methods for reducing the formation of by-products in the production of recombinant polypeptides

Also Published As

Publication number Publication date
AU5406090A (en) 1990-10-09
JPH04504060A (ja) 1992-07-23
HU903721D0 (en) 1991-12-30
EP0463115A1 (en) 1992-01-02
CA2045173A1 (en) 1990-09-16
EP0719792A2 (en) 1996-07-03
EP0463115B1 (en) 1996-09-04
KR920700292A (ko) 1992-02-19
DE69028396T2 (de) 1997-02-13
DE69028396D1 (de) 1996-10-10
HUT58796A (en) 1992-03-30
EP0719792A3 (OSRAM) 1996-07-24
ES2091241T3 (es) 1996-11-01
ATE142270T1 (de) 1996-09-15
WO1990010706A1 (en) 1990-09-20
DK0463115T3 (OSRAM) 1997-02-17

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired