HUT50345A - Process for production of cefem-derivatives and their intermediers - Google Patents

Process for production of cefem-derivatives and their intermediers

Info

Publication number
HUT50345A
HUT50345A HU891247A HU124789A HUT50345A HU T50345 A HUT50345 A HU T50345A HU 891247 A HU891247 A HU 891247A HU 124789 A HU124789 A HU 124789A HU T50345 A HUT50345 A HU T50345A
Authority
HU
Hungary
Prior art keywords
sub
compound
intermediers
cefem
derivatives
Prior art date
Application number
HU891247A
Other languages
English (en)
Other versions
HU215925B (hu
Inventor
Takashi Kamiya
Toshihiko Naito
Yuuki Komatu
Yasunobu Kai
Takaharu Nakamura
Manabu Sasho
Shigeto Negi
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of HUT50345A publication Critical patent/HUT50345A/hu
Publication of HU215925B publication Critical patent/HU215925B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D498/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08Bridged systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C237/00Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
    • C07C237/02Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
    • C07C237/04Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C237/06Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
HU891247A 1988-03-16 1989-03-16 Eljárás cefemszármazékok előállítására HU215925B (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP6051188 1988-03-16

Publications (2)

Publication Number Publication Date
HUT50345A true HUT50345A (en) 1990-01-29
HU215925B HU215925B (hu) 1999-03-29

Family

ID=13144412

Family Applications (1)

Application Number Title Priority Date Filing Date
HU891247A HU215925B (hu) 1988-03-16 1989-03-16 Eljárás cefemszármazékok előállítására

Country Status (12)

Country Link
US (1) US5128465A (hu)
EP (3) EP0764648B1 (hu)
JP (1) JPH07179472A (hu)
CN (1) CN1022837C (hu)
AT (2) ATE212027T1 (hu)
CA (1) CA1339738C (hu)
DE (2) DE68929368T2 (hu)
ES (1) ES2013403A6 (hu)
GR (1) GR1000462B (hu)
HU (1) HU215925B (hu)
PT (1) PT90022B (hu)
YU (1) YU46998B (hu)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254545A (en) * 1989-09-30 1993-10-19 Eisai Co., Ltd. Injectable preparations containing cephalosporin medicament
FR2663332B1 (fr) * 1990-06-15 1997-11-07 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
US5126336A (en) * 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
AT396108B (de) * 1991-08-21 1993-06-25 Biochemie Gmbh Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
KR950014571B1 (ko) * 1991-11-18 1995-12-08 제일제당주식회사 세펨 유도체의 제조방법
GB9216759D0 (en) * 1992-08-07 1992-09-23 Finpael Spa Process for the production of 7-amino thiazolyl cephalosporins
JPH07173168A (ja) * 1993-07-14 1995-07-11 Sumitomo Chem Co Ltd セフェム系化合物、その製法、およびそれのセフェム系抗生物質製造への利用
FR2722790B1 (fr) 1994-07-19 1996-10-04 Roussel Uclaf Nouvelles cephalosporines comportant en position 7 un radical benzyloxymino subtitue, leur procede de preparation leur application comme medicaments
JPH08151354A (ja) 1994-11-29 1996-06-11 Eisai Kagaku Kk アミノアセトアミド誘導体の製造法
KR0174117B1 (ko) * 1995-12-28 1999-02-01 윤원영 새로운 세팔로스포린 유도체 및 그 제조방법
IT1283489B1 (it) * 1996-07-23 1998-04-21 Chiesi Farma Spa Ammidi di alfa-amminoacidi,loro preparazione e loro impiego terapeutico
CA2216259A1 (en) * 1996-09-25 1998-03-25 Eisai Chemical Co., Ltd. Production process of cephem compound
KR100414336B1 (ko) * 1998-06-22 2004-01-07 바실리어 파마슈티카 아게 프로페닐 세팔로스포린 유도체
KR100441901B1 (ko) * 2001-07-02 2004-07-27 일동제약주식회사 세팔로스포린 유도체의 개선된 제조방법
US7214825B2 (en) 2003-10-17 2007-05-08 Honeywell International Inc. O-(3-chloropropenyl) hydroxylamine free base
DK2484680T3 (da) 2005-12-07 2013-09-08 Basilea Pharmaceutica Ag Nyttige kombinationer af monolactam-antibiotika med beta-lactamase-inhibitorer
CN105418641B (zh) * 2015-12-30 2018-08-10 广东金城金素制药有限公司 一种原研制品质头孢曲松钠及其药物制剂
WO2018185211A1 (en) 2017-04-06 2018-10-11 Syngenta Participations Ag Microbiocidal oxadiazole derivatives

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB762850A (en) * 1953-11-09 1956-12-05 Dow Chemical Co Alpha-amino-beta-alkoxy-propionamides
FR1467942A (fr) * 1965-12-23 1967-02-03 Procédé de préparation de dérivés nu-disubstitués de l'aminoacétamide et nouveaux dérivés de ce type
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives
CA1276929C (en) * 1984-04-09 1990-11-27 Masahisa Oka Cephalosporin antibacterial agents
US4751295A (en) * 1984-04-09 1988-06-14 Bristol-Myers Company Cephalosporin derivatives
DE3419012A1 (de) * 1984-05-22 1985-11-28 Bayer Ag, 5090 Leverkusen Ss-lactamantibiotika, verfahren zu deren herstellung sowie ihre verwendung als arzneimittel oder wachstumsfoerderer in der tieraufzucht oder als antioxidantien
DE3650157T2 (de) * 1985-12-26 1995-05-04 Eisai Co Ltd Cephalosporin-verbindungen.
JPH0796502B2 (ja) * 1986-06-16 1995-10-18 東レ株式会社 アミド基の加水分解方法
IL84128A (en) * 1986-10-13 1992-12-01 Eisai Co Ltd 3-propenylcephem derivatives, their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
ATE155469T1 (de) 1997-08-15
EP0764648B1 (en) 2002-01-16
EP0612751A3 (en) 1994-09-21
DE68928174T2 (de) 1997-12-18
EP0333154A3 (en) 1991-10-09
HU215925B (hu) 1999-03-29
PT90022B (pt) 1994-05-31
EP0764648A1 (en) 1997-03-26
YU54189A (en) 1990-12-31
YU46998B (sh) 1994-11-15
EP0333154B1 (en) 1997-07-16
JPH07179472A (ja) 1995-07-18
ES2013403A6 (es) 1990-05-01
EP0612751A2 (en) 1994-08-31
CN1022837C (zh) 1993-11-24
DE68929368D1 (de) 2002-02-21
US5128465A (en) 1992-07-07
ATE212027T1 (de) 2002-02-15
EP0333154A2 (en) 1989-09-20
DE68928174D1 (de) 1997-08-21
PT90022A (pt) 1989-11-10
GR890100162A (en) 1990-01-19
GR1000462B (el) 1992-07-30
DE68929368T2 (de) 2002-08-14
CN1036769A (zh) 1989-11-01
CA1339738C (en) 1998-03-17

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Legal Events

Date Code Title Description
HMM4 Cancellation of final prot. due to non-payment of fee