HUS1500030I1 - Eljárás az ospemifene biohasznosulásának javítására - Google Patents
Eljárás az ospemifene biohasznosulásának javításáraInfo
- Publication number
- HUS1500030I1 HUS1500030I1 HUS1500030C HUS1500030C HUS1500030I1 HU S1500030 I1 HUS1500030 I1 HU S1500030I1 HU S1500030 C HUS1500030 C HU S1500030C HU S1500030 C HUS1500030 C HU S1500030C HU S1500030 I1 HUS1500030 I1 HU S1500030I1
- Authority
- HU
- Hungary
- Prior art keywords
- bioavailability
- ospemifene
- improving
- compound
- stereoisomer
- Prior art date
Links
- LUMKNAVTFCDUIE-VHXPQNKSSA-N ospemifene Chemical compound C1=CC(OCCO)=CC=C1C(\C=1C=CC=CC=1)=C(\CCCl)C1=CC=CC=C1 LUMKNAVTFCDUIE-VHXPQNKSSA-N 0.000 title 1
- 229960003969 ospemifene Drugs 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000002708 enhancing effect Effects 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 239000002207 metabolite Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/30—Dietetic or nutritional methods, e.g. for losing weight
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nutrition Science (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Mycology (AREA)
- Reproductive Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Rheumatology (AREA)
- Physiology (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/777,211 US8236861B2 (en) | 2004-02-13 | 2004-02-13 | Method for enhancing the bioavailablity of ospemifene |
| EP05701734A EP1713458B1 (en) | 2004-02-13 | 2005-01-14 | Method for enhancing the bioavailability of ospemifene |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUS1500030I1 true HUS1500030I1 (hu) | 2015-08-28 |
Family
ID=34837941
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUS1500030C HUS1500030I1 (hu) | 2004-02-13 | 2015-06-16 | Eljárás az ospemifene biohasznosulásának javítására |
Country Status (23)
| Country | Link |
|---|---|
| US (5) | US8236861B2 (en:Method) |
| EP (1) | EP1713458B1 (en:Method) |
| JP (2) | JP5577011B2 (en:Method) |
| CN (1) | CN1925847A (en:Method) |
| AT (1) | ATE387910T1 (en:Method) |
| AU (1) | AU2005211958B2 (en:Method) |
| BE (1) | BE2015C033I2 (en:Method) |
| BR (1) | BRPI0507661A (en:Method) |
| CA (1) | CA2556089C (en:Method) |
| CY (2) | CY1111014T1 (en:Method) |
| DE (1) | DE602005005165T2 (en:Method) |
| DK (1) | DK1713458T5 (en:Method) |
| ES (1) | ES2302177T3 (en:Method) |
| FR (1) | FR15C0041I2 (en:Method) |
| HU (1) | HUS1500030I1 (en:Method) |
| LT (1) | LTC1713458I2 (en:Method) |
| LU (1) | LU92736I2 (en:Method) |
| MX (1) | MXPA06009274A (en:Method) |
| NO (2) | NO337656B1 (en:Method) |
| PL (1) | PL1713458T3 (en:Method) |
| PT (1) | PT1713458E (en:Method) |
| RU (1) | RU2385716C2 (en:Method) |
| WO (1) | WO2005077350A1 (en:Method) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8236861B2 (en) | 2004-02-13 | 2012-08-07 | Hormos Medical Corporation | Method for enhancing the bioavailablity of ospemifene |
| US8642079B2 (en) * | 2004-02-23 | 2014-02-04 | Hormos Medical Corporation | Solid formulations of ospemifene |
| SI1742618T1 (sl) | 2004-05-04 | 2012-12-31 | Hormos Medical Ltd. | Tekoäśe oralne formulacije ospemifena |
| US8758821B2 (en) * | 2004-05-04 | 2014-06-24 | Hormos Medical Ltd. | Oral formulations of ospemifene |
| WO2007099410A2 (en) * | 2005-11-09 | 2007-09-07 | Hormos Medical Ltd. | Formulations of fispemifene |
| US8637706B2 (en) | 2005-11-28 | 2014-01-28 | Gtx, Inc. | Nuclear receptor binding agents |
| EA023472B1 (ru) * | 2005-11-28 | 2016-06-30 | Джи Ти Икс, ИНК. | Агенты, связывающиеся с ядерными рецепторами |
| US9409856B2 (en) | 2005-11-28 | 2016-08-09 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
| US8546451B2 (en) | 2005-11-28 | 2013-10-01 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
| US8158828B2 (en) * | 2005-11-28 | 2012-04-17 | Gtx, Inc. | Nuclear receptor binding agents |
| US7504530B2 (en) * | 2007-02-14 | 2009-03-17 | Hormos Medical Ltd. | Methods for the preparation of fispemifene from ospemifene |
| KR101510646B1 (ko) * | 2007-02-14 | 2015-04-10 | 호르모스 메디칼 리미티드 | 치료적으로 유용한 트리페닐부텐 유도체의 제조 방법 |
| US9427418B2 (en) | 2009-02-23 | 2016-08-30 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
| US9624161B2 (en) | 2009-02-23 | 2017-04-18 | Gtx, Inc. | Estrogen receptor ligands and methods of use thereof |
| US9321712B2 (en) | 2012-10-19 | 2016-04-26 | Fermion Oy | Process for the preparation of ospemifene |
| CN103739456A (zh) * | 2013-12-03 | 2014-04-23 | 镇江圣安医药有限公司 | 2-（对-（（z-4-氯-1,2-二苯基-1-丁烯基）苯氧基）乙醇的新型衍生物及其应用 |
| GR1009542B (el) | 2018-04-25 | 2019-06-07 | Φαρματεν Α.Β.Ε.Ε. | Καψουλα μαλακης γελης που περιλαμβανει εναν εκλεκτικο ρυθμιστη οιστρογονικων υποδοχεων |
| DK3790548T3 (da) | 2018-05-11 | 2023-11-13 | Xenon Pharmaceuticals Inc | Fremgangsmåder til forbedring af biotilgængeligheden og eksponeringen af en åbner af spændingsstyret kaliumkanal |
| TWI886158B (zh) | 2019-10-10 | 2025-06-11 | 加拿大商再諾製藥公司 | 選擇性鉀通道調節劑之固態晶型 |
| TW202128162A (zh) | 2019-11-08 | 2021-08-01 | 加拿大商再諾製藥公司 | 憂鬱症之治療方法 |
| JP2024508660A (ja) | 2021-02-09 | 2024-02-28 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | 快感消失の治療に使用するための電位依存性カリウムチャネル開口薬 |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9007052D0 (en) * | 1990-03-29 | 1990-05-30 | Skua Investments Ltd | Pharmaceutical formulations |
| GB9207437D0 (en) * | 1992-04-03 | 1992-05-20 | Orion Yhtymae Oy | Topical administration of toremifene and its metabolites |
| GB9418067D0 (en) | 1994-09-07 | 1994-10-26 | Orion Yhtymae Oy | Triphenylethylenes for the prevention and treatment of osteoporosis |
| GB9604577D0 (en) | 1996-03-04 | 1996-05-01 | Orion Yhtymae Oy | Serum cholesterol lowering agent |
| ES2255294T3 (es) * | 1998-08-07 | 2006-06-16 | Chiron Corporation | Derivados de isoxazol sustituidos como moduladores del receptor de estrogenos. |
| US6219674B1 (en) * | 1999-11-24 | 2001-04-17 | Classen Immunotherapies, Inc. | System for creating and managing proprietary product data |
| US6245819B1 (en) * | 2000-07-21 | 2001-06-12 | Hormos Medical Oy, Ltd. | Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause |
| US6653639B1 (en) * | 2000-10-17 | 2003-11-25 | Nikon Corporation | Chuck for mounting reticle to a reticle stage |
| CA2438816A1 (en) | 2001-02-22 | 2002-09-06 | Classen Immunotherapies, Inc. | Improved algorithms and methods for products safety |
| FR2826811B1 (fr) | 2001-06-27 | 2003-11-07 | France Telecom | Procede d'authentification cryptographique |
| PT1509215E (pt) | 2002-06-06 | 2007-01-31 | Hormos Medical Ltd | Tratamento ou profilaxia da atrofia urogenital e seus sintomas em mulheres |
| US8236861B2 (en) | 2004-02-13 | 2012-08-07 | Hormos Medical Corporation | Method for enhancing the bioavailablity of ospemifene |
| US8642079B2 (en) * | 2004-02-23 | 2014-02-04 | Hormos Medical Corporation | Solid formulations of ospemifene |
| US20050187302A1 (en) * | 2004-02-23 | 2005-08-25 | Hormos Medical Corporation | Method for treatment or prevention of osteoporosis in individuals with high bone turnover |
| US8758821B2 (en) * | 2004-05-04 | 2014-06-24 | Hormos Medical Ltd. | Oral formulations of ospemifene |
| US20060293294A1 (en) | 2004-09-03 | 2006-12-28 | Hormos Medical Corporation | Method for treatment or prevention of androgen deficiency |
| KR100665758B1 (ko) * | 2005-09-15 | 2007-01-09 | 제일모직주식회사 | 반사방지성을 갖는 하드마스크 조성물 |
-
2004
- 2004-02-13 US US10/777,211 patent/US8236861B2/en active Active
-
2005
- 2005-01-14 EP EP05701734A patent/EP1713458B1/en not_active Expired - Lifetime
- 2005-01-14 BR BRPI0507661-7A patent/BRPI0507661A/pt not_active Application Discontinuation
- 2005-01-14 CA CA2556089A patent/CA2556089C/en not_active Expired - Lifetime
- 2005-01-14 WO PCT/FI2005/000018 patent/WO2005077350A1/en not_active Ceased
- 2005-01-14 DE DE602005005165T patent/DE602005005165T2/de not_active Expired - Lifetime
- 2005-01-14 CN CNA200580004550XA patent/CN1925847A/zh active Pending
- 2005-01-14 ES ES05701734T patent/ES2302177T3/es not_active Expired - Lifetime
- 2005-01-14 JP JP2006552639A patent/JP5577011B2/ja not_active Expired - Fee Related
- 2005-01-14 AT AT05701734T patent/ATE387910T1/de active
- 2005-01-14 PT PT05701734T patent/PT1713458E/pt unknown
- 2005-01-14 DK DK05701734T patent/DK1713458T5/da active
- 2005-01-14 AU AU2005211958A patent/AU2005211958B2/en not_active Ceased
- 2005-01-14 RU RU2006132719/15A patent/RU2385716C2/ru active
- 2005-01-14 MX MXPA06009274A patent/MXPA06009274A/es active IP Right Grant
- 2005-01-14 PL PL05701734T patent/PL1713458T3/pl unknown
-
2006
- 2006-09-05 NO NO20063960A patent/NO337656B1/no unknown
-
2008
- 2008-04-24 CY CY20081100456T patent/CY1111014T1/el unknown
-
2012
- 2012-07-06 US US13/543,166 patent/US8470890B2/en not_active Expired - Fee Related
-
2013
- 2013-05-29 US US13/904,818 patent/US8772353B2/en not_active Expired - Lifetime
-
2014
- 2014-05-12 JP JP2014098549A patent/JP6023119B2/ja not_active Expired - Fee Related
- 2014-06-20 US US14/310,822 patent/US9241915B2/en not_active Expired - Fee Related
-
2015
- 2015-06-10 BE BE2015C033C patent/BE2015C033I2/fr unknown
- 2015-06-10 LU LU92736C patent/LU92736I2/xx unknown
- 2015-06-11 FR FR15C0041C patent/FR15C0041I2/fr active Active
- 2015-06-16 HU HUS1500030C patent/HUS1500030I1/hu unknown
- 2015-06-25 LT LTPA2015023C patent/LTC1713458I2/lt unknown
- 2015-07-08 CY CY2015027C patent/CY2015027I2/el unknown
- 2015-11-25 NO NO20151603A patent/NO339190B1/no unknown
- 2015-12-16 US US14/971,252 patent/US9855224B2/en not_active Expired - Lifetime
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