HUP0302455A3 - Combination pharmaceutical compositions containing amplodipine and benazepril and their use - Google Patents

Combination pharmaceutical compositions containing amplodipine and benazepril and their use

Info

Publication number
HUP0302455A3
HUP0302455A3 HU0302455A HUP0302455A HUP0302455A3 HU P0302455 A3 HUP0302455 A3 HU P0302455A3 HU 0302455 A HU0302455 A HU 0302455A HU P0302455 A HUP0302455 A HU P0302455A HU P0302455 A3 HUP0302455 A3 HU P0302455A3
Authority
HU
Hungary
Prior art keywords
amplodipine
benazepril
pharmaceutical compositions
compositions containing
combination pharmaceutical
Prior art date
Application number
HU0302455A
Other languages
English (en)
Hungarian (hu)
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21742073&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0302455(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of HUP0302455A2 publication Critical patent/HUP0302455A2/hu
Publication of HUP0302455A3 publication Critical patent/HUP0302455A3/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pulmonology (AREA)
  • Emergency Medicine (AREA)
  • Vascular Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
HU0302455A 2000-12-18 2000-12-18 Combination pharmaceutical compositions containing amplodipine and benazepril and their use HUP0302455A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/034246 WO2002049645A1 (en) 2000-12-18 2000-12-18 Therapeutic combination of amlodipine and benazepril

Publications (2)

Publication Number Publication Date
HUP0302455A2 HUP0302455A2 (hu) 2003-11-28
HUP0302455A3 true HUP0302455A3 (en) 2005-05-30

Family

ID=21742073

Family Applications (2)

Application Number Title Priority Date Filing Date
HU0302455A HUP0302455A3 (en) 2000-12-18 2000-12-18 Combination pharmaceutical compositions containing amplodipine and benazepril and their use
HU0302456A HUP0302456A3 (en) 2000-12-18 2001-12-17 Combination pharmaceutical compositions containing of amlodipine and benazepril and their use and preparation

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU0302456A HUP0302456A3 (en) 2000-12-18 2001-12-17 Combination pharmaceutical compositions containing of amlodipine and benazepril and their use and preparation

Country Status (26)

Country Link
EP (3) EP1365761A1 (https=)
JP (3) JP2004516266A (https=)
KR (3) KR20040007420A (https=)
CN (2) CN1461218A (https=)
AT (1) ATE338549T1 (https=)
AU (4) AU2581601A (https=)
BR (2) BR0017386A (https=)
CA (2) CA2432638A1 (https=)
CY (1) CY1106275T1 (https=)
CZ (2) CZ20031678A3 (https=)
DE (1) DE60122928T2 (https=)
DK (1) DK1345607T3 (https=)
EC (1) ECSP034658A (https=)
ES (1) ES2272565T3 (https=)
HU (2) HUP0302455A3 (https=)
IL (4) IL156136A0 (https=)
MX (2) MXPA03005462A (https=)
NO (2) NO20032766L (https=)
NZ (1) NZ526467A (https=)
PL (2) PL362252A1 (https=)
PT (1) PT1345607E (https=)
RU (1) RU2292206C2 (https=)
SI (1) SI1345607T1 (https=)
SK (2) SK7652003A3 (https=)
WO (2) WO2002049645A1 (https=)
ZA (1) ZA200304514B (https=)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2467095A1 (en) * 2001-11-23 2003-05-30 Solvay Pharmaceuticals Gmbh Hypertonia treatment during the acute phase of a cerebrovascular accident
US20040229901A1 (en) * 2003-02-24 2004-11-18 Lauren Otsuki Method of treatment of disease using an adenosine A1 receptor antagonist
MXPA05011371A (es) 2003-04-25 2005-12-01 Novacardia Inc Metodo para mejorar la diuresis en individuos con la funcion renal deteriorada.
TW200524591A (en) * 2003-10-20 2005-08-01 Novartis Ag Use of organic compounds
WO2005074927A1 (en) * 2004-02-09 2005-08-18 Novartis Ag Therapeutic combination of amlodipine and benazepril/ benazeprilat for the treatment of hypertension
WO2005079772A2 (en) * 2004-02-18 2005-09-01 Sepracor Inc. Combination of (s)-amlodipine and an ace inhibitor, and methods for reducing hypertension
DE102004011512B4 (de) 2004-03-08 2022-01-13 Boehringer Ingelheim Vetmedica Gmbh Pharmazeutische Zubereitung enthaltend Pimobendan
US8980894B2 (en) 2004-03-25 2015-03-17 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the treatment of asymptomatic (occult) heart failure
EP1579862A1 (en) 2004-03-25 2005-09-28 Boehringer Ingelheim Vetmedica Gmbh Use of PDE III inhibitors for the reduction of heart size in mammals suffering from heart failure
WO2006085208A2 (en) * 2005-02-11 2006-08-17 Ranbaxy Laboratories Limited Stable solid dosage forms of amlodipine and benazepril
WO2006092732A2 (en) * 2005-03-04 2006-09-08 Aurobindo Pharma Ltd Stable solid dosage form of antihypertensive agent
AU2006224161A1 (en) 2005-03-15 2006-09-21 Lupin Limited Pharmaceutical compositions of amlodipine and benazepril
US8158146B2 (en) 2005-09-28 2012-04-17 Teva Pharmaceutical Industries Ltd. Stable combinations of amlodipine besylate and benazepril hydrochloride
WO2007040511A1 (en) * 2005-09-28 2007-04-12 Teva Pharmaceutical Industries Ltd. Stable combinations of amlodipine besylate and benazepril hydrochloride
DK1797885T3 (da) * 2005-09-28 2008-07-14 Teva Pharma Stabil kombination af amlodipinbesylat og benazeprilhydrochlorid
EP1920785A1 (en) 2006-11-07 2008-05-14 Boehringer Ingelheim Vetmedica Gmbh Liquid preparation comprising a complex of pimobendan and cyclodextrin
IT1398168B1 (it) * 2010-02-16 2013-02-14 Chiesi Farma Spa Uso di ingredienti attivi in combinazione per il trattamento delle complicanze del diabete.
EP2585051B2 (en) 2010-06-23 2020-04-08 KRKA, tovarna zdravil, d.d., Novo mesto Pharmaceutical oral dosage forms comprising lercanidipine and enalapril and their pharmaceutically acceptable salts
CN102389431A (zh) * 2011-09-28 2012-03-28 济南龙华医药技术有限公司 一种含有盐酸贝尼地平和盐酸贝那普利的复方制剂及其应用
AU2012357795B2 (en) 2011-12-21 2017-04-06 Elanco Tiergesundheit Ag New combination
EP3167876B1 (en) 2012-03-15 2021-09-08 Boehringer Ingelheim Vetmedica GmbH Pharmaceutical tablet formulation for the veterinary medical sector, method of production and use thereof
WO2014035707A1 (en) * 2012-08-25 2014-03-06 The Johns Hopkins University Gapdh cascade inhibitor compounds and methods of use and treatment of stress induced disorders including mental illness
EP3021832B9 (en) 2013-07-19 2023-03-15 Boehringer Ingelheim Vetmedica GmbH Preserved etherified cyclodextrin derivatives containing liquid aqueous pharmaceutical composition
CA2930033C (en) 2013-12-04 2022-12-13 Boehringer Ingelheim Vetmedica Gmbh Improved pharmaceutical compositions of pimobendan
CN108778334A (zh) * 2016-03-24 2018-11-09 第三共株式会社 用于治疗肾脏疾病的药物
US10537570B2 (en) 2016-04-06 2020-01-21 Boehringer Ingelheim Vetmedica Gmbh Use of pimobendan for the reduction of heart size and/or the delay of onset of clinical symptoms in patients with asymptomatic heart failure due to mitral valve disease
UA124884C2 (uk) 2016-11-16 2021-12-08 Лундбек Ла Джолла Ресеарч Центер, Інк. Фармацевтичні склади
MA46866B1 (fr) 2016-11-16 2021-11-30 H Lundbeck As Une forme cristalline d'un inhibiteur de magl

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6162802A (en) * 1992-03-10 2000-12-19 Papa; Joseph Synergistic combination therapy using benazepril and amlodipine for the treatment of cardiovascular disorders and compositions therefor
JPH11500140A (ja) * 1995-03-16 1999-01-06 ファイザー・インコーポレーテッド アムロジピン、アムロジピン塩、もしくはフェロジピンとａｃｅ阻害薬とを含有する組成物
TR199701121T1 (xx) * 1995-04-07 1998-03-21 Novartis Ag Benazepril veya benazeprilat ve valsartan i�eren kombinasyon bile�imleri.
EP0795327A1 (en) * 1996-03-13 1997-09-17 Pfizer Inc. Use of Amlodipine for the treatment and prophylaxis of congestive cardiac failure of non-ischaemic origin

Also Published As

Publication number Publication date
EP1674099A1 (en) 2006-06-28
NO20032765L (no) 2003-08-14
AU2002232620B9 (en) 2005-11-24
AU2002232620B2 (en) 2005-11-03
ES2272565T3 (es) 2007-05-01
NO20032765D0 (no) 2003-06-17
CY1106275T1 (el) 2011-10-12
PL362252A1 (en) 2004-10-18
KR20030061840A (ko) 2003-07-22
RU2292206C2 (ru) 2007-01-27
IL190802A0 (en) 2008-11-03
PT1345607E (pt) 2007-01-31
EP1365761A1 (en) 2003-12-03
CA2432282A1 (en) 2002-06-27
HUP0302455A2 (hu) 2003-11-28
CN1461218A (zh) 2003-12-10
EP1345607B1 (en) 2006-09-06
ECSP034658A (es) 2003-07-25
SK7652003A3 (en) 2003-12-02
ZA200304514B (en) 2004-05-10
CZ20031677A3 (cs) 2003-10-15
ATE338549T1 (de) 2006-09-15
JP2004519440A (ja) 2004-07-02
IL156267A0 (en) 2004-01-04
CN1481241A (zh) 2004-03-10
RU2003121019A (ru) 2005-01-20
DK1345607T3 (da) 2006-12-27
SI1345607T1 (sl) 2007-02-28
DE60122928T2 (de) 2007-09-06
SK7642003A3 (en) 2003-11-04
IL190801A0 (en) 2008-11-03
DE60122928D1 (de) 2006-10-19
KR20090033914A (ko) 2009-04-06
MXPA03005462A (es) 2003-09-25
KR20040007420A (ko) 2004-01-24
CZ301424B6 (cs) 2010-02-24
HK1059566A1 (en) 2004-07-09
NZ526467A (en) 2005-04-29
JP2010043111A (ja) 2010-02-25
PL360989A1 (en) 2004-09-20
AU3262002A (en) 2002-07-01
WO2002049645A1 (en) 2002-06-27
IL156136A0 (en) 2003-12-23
BR0017386A (pt) 2004-01-13
NO20032766L (no) 2003-08-14
HUP0302456A2 (hu) 2003-11-28
AU2001225816B2 (en) 2005-10-13
CZ20031678A3 (cs) 2003-10-15
AU2581601A (en) 2002-07-01
BR0116228A (pt) 2003-12-30
EP1345607A1 (en) 2003-09-24
NO20032766D0 (no) 2003-06-17
MXPA03005463A (es) 2003-09-25
JP2004516266A (ja) 2004-06-03
CA2432638A1 (en) 2002-06-27
WO2002049646A1 (en) 2002-06-27
HUP0302456A3 (en) 2004-05-28

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Legal Events

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