DK1797885T3 - Stabil kombination af amlodipinbesylat og benazeprilhydrochlorid - Google Patents

Stabil kombination af amlodipinbesylat og benazeprilhydrochlorid

Info

Publication number
DK1797885T3
DK1797885T3 DK05256202T DK05256202T DK1797885T3 DK 1797885 T3 DK1797885 T3 DK 1797885T3 DK 05256202 T DK05256202 T DK 05256202T DK 05256202 T DK05256202 T DK 05256202T DK 1797885 T3 DK1797885 T3 DK 1797885T3
Authority
DK
Denmark
Prior art keywords
amlodipine besylate
stable combination
benazepril hydrochloride
benazepril
hydrochloride
Prior art date
Application number
DK05256202T
Other languages
English (en)
Inventor
Mali Kadosh
Fanny Leska
Original Assignee
Teva Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/238,496 external-priority patent/US8158146B2/en
Priority claimed from PCT/US2005/034930 external-priority patent/WO2007040511A1/en
Application filed by Teva Pharma filed Critical Teva Pharma
Application granted granted Critical
Publication of DK1797885T3 publication Critical patent/DK1797885T3/da

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/44221,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4858Organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841Filling excipients; Inactive ingredients
    • A61K9/4866Organic macromolecular compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5084Mixtures of one or more drugs in different galenical forms, at least one of which being granules, microcapsules or (coated) microparticles according to A61K9/16 or A61K9/50, e.g. for obtaining a specific release pattern or for combining different drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1635Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK05256202T 2005-09-28 2005-10-04 Stabil kombination af amlodipinbesylat og benazeprilhydrochlorid DK1797885T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/238,496 US8158146B2 (en) 2005-09-28 2005-09-28 Stable combinations of amlodipine besylate and benazepril hydrochloride
PCT/US2005/034930 WO2007040511A1 (en) 2005-09-28 2005-09-28 Stable combinations of amlodipine besylate and benazepril hydrochloride

Publications (1)

Publication Number Publication Date
DK1797885T3 true DK1797885T3 (da) 2008-07-14

Family

ID=35455329

Family Applications (1)

Application Number Title Priority Date Filing Date
DK05256202T DK1797885T3 (da) 2005-09-28 2005-10-04 Stabil kombination af amlodipinbesylat og benazeprilhydrochlorid

Country Status (6)

Country Link
EP (3) EP1797885B1 (da)
DE (1) DE602005005706T2 (da)
DK (1) DK1797885T3 (da)
ES (1) ES2303198T3 (da)
HK (1) HK1103658A1 (da)
PT (1) PT1797885E (da)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2024052498A1 (en) 2022-09-07 2024-03-14 Kinast Lasse An immediate-release oral pharmaceutical form of amlodipine with increased api content

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8608335D0 (en) * 1986-04-04 1986-05-08 Pfizer Ltd Pharmaceutically acceptable salts
US6162802A (en) 1992-03-10 2000-12-19 Papa; Joseph Synergistic combination therapy using benazepril and amlodipine for the treatment of cardiovascular disorders and compositions therefor
WO1999018957A1 (en) * 1998-03-26 1999-04-22 Reddy-Cheminor, Inc. Stable pharmaceutical composition containing amlodipine besylate and atenolol
US8168616B1 (en) * 2000-11-17 2012-05-01 Novartis Ag Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension
IL156136A0 (en) * 2000-12-18 2003-12-23 Novartis Ag Therapeutic combination of amlodipine and benazepril
AT5874U1 (de) * 2000-12-29 2003-01-27 Bioorg Bv Pharmazeutische zubereitungen enthaltend amlodipinmaleat
CA2343949A1 (en) * 2001-04-12 2002-10-12 Bernard Charles Sherman Benazepril hydrochloride tablet formulations
US20040001886A1 (en) * 2001-10-17 2004-01-01 Dr. Reddy's Laboratories Limited Stabilized pharmaceutical formulations containing amlodipine maleate
GB2394660A (en) * 2003-12-17 2004-05-05 Niche Generics Ltd Stabilisation of pharmaceutical compositions comprising ACE inhibitor by absence of acidic excipients having large specific surface area, eg silicon dioxide

Also Published As

Publication number Publication date
EP1932528A1 (en) 2008-06-18
DE602005005706D1 (de) 2008-05-08
HK1103658A1 (en) 2007-12-28
DE602005005706T2 (de) 2009-04-16
EP1930008A1 (en) 2008-06-11
ES2303198T3 (es) 2008-08-01
PT1797885E (pt) 2008-05-20
EP1797885A1 (en) 2007-06-20
EP1797885B1 (en) 2008-03-26

Similar Documents

Publication Publication Date Title
DK1802579T3 (da) Derivater af 3-arylaminopyridin
DK1937824T3 (da) Sammensætninger af tRNA og anvendelser deraf
DK3385267T3 (da) Syntese af boronestere og syreforbindelser
DE502005007430D1 (de) Akkuschrauber
DE502005005415D1 (de) Akkuschrauber
DK1954140T3 (da) Glycerollevulinatketaler og deres anvendelse
DK1771446T3 (da) Azaindolinhibitorer af MTP og APOB
DK1992697T3 (da) Fremstilling af TNFR-Fc
DK1831154T3 (da) Fremstilling af pregabalin og relaterede forbindelser
DK2363414T3 (da) Stedstyret modifikation af FVIII
NO20055837D0 (no) Immunsupprimerende forbindelser og sammensetninger
DE602005002793D1 (de) Klemmeinsatz
DK1737971T3 (da) Blandinger af bindingsproteiner
DE602005004072D1 (de) Sicherungsanordnung
DK1814977T3 (da) Arthrospira-baserede sammensætninger og anvendelser deraf
EP1773339A4 (en) CRYSTALLINE FORM OF DONEPEZIL HYDROCHLORIDE
IS8705A (is) Kristallaður basi af essítalóprami og munndreifitöflur sem samanstanda af essítalópram basa
IS8109A (is) Nýjar 3-dekladínósýl 9a-N-karbamóýl og 9a-N-þíókarbamóýl afleiður af 9-deoxó-9-díhýdró-9a-asa-9a-hómóerýþrómýsíni A
IL189613A0 (en) Stable combinations of amlodipine besylate and benazepril hydrochloride
DK1772113T3 (da) Sæt af vinklede understøtningselementer udformet ud i ét
DE502004006154D1 (de) Brandmelder
FI20040193A (fi) Rakennus
ZA200708126B (en) Lercanidipine free base
DK1797885T3 (da) Stabil kombination af amlodipinbesylat og benazeprilhydrochlorid
FI20040129A (fi) Ympäristösulake