HUP0301791A2 - Eljárás klimaktériummal összefüggő rendellenességek kezelésére nőkben a menopauza alatt vagy után - Google Patents
Eljárás klimaktériummal összefüggő rendellenességek kezelésére nőkben a menopauza alatt vagy utánInfo
- Publication number
- HUP0301791A2 HUP0301791A2 HU0301791A HUP0301791A HUP0301791A2 HU P0301791 A2 HUP0301791 A2 HU P0301791A2 HU 0301791 A HU0301791 A HU 0301791A HU P0301791 A HUP0301791 A HU P0301791A HU P0301791 A2 HUP0301791 A2 HU P0301791A2
- Authority
- HU
- Hungary
- Prior art keywords
- menopause
- treatment
- women during
- climacteric disorders
- deaminohydroxy
- Prior art date
Links
- 230000009245 menopause Effects 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- 206010047791 Vulvovaginal dryness Diseases 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 150000002148 esters Chemical class 0.000 abstract 2
- 239000002207 metabolite Substances 0.000 abstract 2
- LUMKNAVTFCDUIE-VHXPQNKSSA-N ospemifene Chemical compound C1=CC(OCCO)=CC=C1C(\C=1C=CC=CC=1)=C(\CCCl)C1=CC=CC=C1 LUMKNAVTFCDUIE-VHXPQNKSSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 208000012201 sexual and gender identity disease Diseases 0.000 abstract 2
- 208000015891 sexual disease Diseases 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
- A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/075—Ethers or acetals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/30—Oestrogens
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Gynecology & Obstetrics (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Plant Substances (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Steroid Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A találmány tárgya eljárás vaginakiszáradás vagy szexuális zavarokkezelésére menopauza alatti vagy utáni nőkben, ahol a nőnek a(deaminohidroxi)-toremifén kémiai nevű vegyület vagy annakgyógyászatilag elfogadható sója, észtere vagy metabolitja hatásosmennyiségét adják be. A találmány tárgya továbbá a (deaminohidroxi)-toremifén kémiai nevű vegyület, annak gyógyászatilag elfogadható sója,észtere vagy metabolitja alkalmazása nőkben menopauza alatt vagy utánvaginakiszáradás vagy szexuális zavarok kezelésére szolgálógyógyszerkészítmény előállítására. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/625,199 US6245819B1 (en) | 2000-07-21 | 2000-07-21 | Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause |
PCT/FI2001/000414 WO2002007718A1 (en) | 2000-07-21 | 2001-05-02 | Method for the treatment of climacteric disorders in women during or after the menopause |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0301791A2 true HUP0301791A2 (hu) | 2003-12-29 |
HUP0301791A3 HUP0301791A3 (en) | 2008-01-28 |
HU229361B1 HU229361B1 (en) | 2013-11-28 |
Family
ID=24504996
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0301791A HU229361B1 (en) | 2000-07-21 | 2001-05-02 | Method for the treatment of climacteric disorders in women during or after the menopause |
Country Status (31)
Country | Link |
---|---|
US (5) | US6245819B1 (hu) |
EP (1) | EP1305014B1 (hu) |
JP (2) | JP5575351B2 (hu) |
KR (1) | KR100880564B1 (hu) |
CN (1) | CN1287775C (hu) |
AT (1) | ATE300289T1 (hu) |
AU (2) | AU2001258449B2 (hu) |
BG (1) | BG65943B1 (hu) |
BR (1) | BR0112659A (hu) |
CA (1) | CA2416480C (hu) |
CY (1) | CY1105370T1 (hu) |
CZ (1) | CZ299439B6 (hu) |
DE (1) | DE60112301T2 (hu) |
DK (1) | DK1305014T3 (hu) |
EE (1) | EE05344B1 (hu) |
ES (1) | ES2241819T3 (hu) |
HK (1) | HK1056694A1 (hu) |
HR (1) | HRP20030024A2 (hu) |
HU (1) | HU229361B1 (hu) |
IL (1) | IL153823A (hu) |
MX (1) | MXPA03000378A (hu) |
NO (1) | NO329954B1 (hu) |
NZ (1) | NZ524181A (hu) |
PL (1) | PL202654B1 (hu) |
PT (1) | PT1305014E (hu) |
RU (1) | RU2268035C2 (hu) |
SI (1) | SI1305014T1 (hu) |
SK (1) | SK287096B6 (hu) |
UA (1) | UA74386C2 (hu) |
WO (1) | WO2002007718A1 (hu) |
ZA (1) | ZA200300342B (hu) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL120266A (en) | 1996-02-28 | 2005-05-17 | Pfizer | Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions |
US20020013327A1 (en) * | 2000-04-18 | 2002-01-31 | Lee Andrew G. | Compositions and methods for treating female sexual dysfunction |
AU2001261244B2 (en) * | 2000-05-09 | 2006-08-03 | Nitromed, Inc. | Infrared thermography and methods of use |
US6245819B1 (en) * | 2000-07-21 | 2001-06-12 | Hormos Medical Oy, Ltd. | Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause |
CN101406464A (zh) * | 2002-06-06 | 2009-04-15 | 霍尔莫斯医疗有限公司 | 抑制女性萎缩或治疗或预防与女性萎缩相关的症状的方法 |
JP2006515276A (ja) * | 2002-10-22 | 2006-05-25 | オスコテック株式会社 | 骨粗鬆症の予防及び治療効果を有するフラン誘導体並びにこれを含む薬学的組成物 |
US20040248989A1 (en) | 2003-06-05 | 2004-12-09 | Risto Santti | Method for the treatment or prevention of lower urinary tract symptoms |
US8236861B2 (en) | 2004-02-13 | 2012-08-07 | Hormos Medical Corporation | Method for enhancing the bioavailablity of ospemifene |
US8642079B2 (en) * | 2004-02-23 | 2014-02-04 | Hormos Medical Corporation | Solid formulations of ospemifene |
US20050187302A1 (en) * | 2004-02-23 | 2005-08-25 | Hormos Medical Corporation | Method for treatment or prevention of osteoporosis in individuals with high bone turnover |
DK1742618T3 (da) | 2004-05-04 | 2012-10-01 | Hormos Medical Ltd | Flydende orale formuleringer af ospemifen |
US8758821B2 (en) | 2004-05-04 | 2014-06-24 | Hormos Medical Ltd. | Oral formulations of ospemifene |
KR100734942B1 (ko) | 2007-01-02 | 2007-07-03 | 김재현 | 여성 갱년기 증후군에 유효한 건강기능식품 조성물 |
US7504530B2 (en) * | 2007-02-14 | 2009-03-17 | Hormos Medical Ltd. | Methods for the preparation of fispemifene from ospemifene |
ES2389961T3 (es) | 2007-02-14 | 2012-11-05 | Hormos Medical Ltd. | Método para la preparación de derivados de trifenilbuteno con valor terapéutico |
US20080293683A1 (en) * | 2007-05-24 | 2008-11-27 | University Of Kansas Medical Center | Hormone Replacement Therapy |
RU2535112C2 (ru) * | 2012-09-19 | 2014-12-10 | Государственное бюджетное образовательное учреждение высшего профессионального образования "Дагестанская государственная медицинская академия министерства здравоохранения и социального развития" | Способ лечения климактерических и урогенитальных расстройств у женщин в постменопаузе на фоне гипотириоза |
US9321712B2 (en) | 2012-10-19 | 2016-04-26 | Fermion Oy | Process for the preparation of ospemifene |
RU2694832C2 (ru) | 2015-03-10 | 2019-07-17 | Шионоги Инк. | Твёрдые дисперсии |
CN107530321B (zh) * | 2015-03-19 | 2022-12-30 | Gto制药有限责任公司 | 针对女性性障碍的治疗化合物和治疗形式 |
RU2636619C1 (ru) * | 2017-02-20 | 2017-11-24 | Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени академика В.И. Кулакова" Министерства здравоохранения Российской Федерации | Способ лечения вагинальной атрофии у женщин в постменопаузе с учетом состояния эпителия и микробиоценоза влагалища |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5352699A (en) | 1992-04-30 | 1994-10-04 | University Of Massachusetts Medical Center | Use of retinioc acid to treat vaginal atrophy |
US5461064A (en) | 1993-12-21 | 1995-10-24 | Eli Lilly And Company | Methods of inhibiting atrophy of the skin and vagina |
GB9418067D0 (en) | 1994-09-07 | 1994-10-26 | Orion Yhtymae Oy | Triphenylethylenes for the prevention and treatment of osteoporosis |
US5747059A (en) | 1996-01-11 | 1998-05-05 | Novo Nordisk A/S | Atrophy of skin/mucous membrane |
GB9604577D0 (en) | 1996-03-04 | 1996-05-01 | Orion Yhtymae Oy | Serum cholesterol lowering agent |
CO5271697A1 (es) * | 2000-01-12 | 2003-04-30 | Pfizer Prod Inc | Composiciones y procedimientos para el tratamiento de afecciones que responden a un aumento de testosterona |
SK9592002A3 (en) | 2000-01-28 | 2003-12-02 | Endorech Inc | A method for reduction or elimination of the incidence of menopausal symptoms, method of treatment or decreasing the risk of an acquiring disease, a pharmaceutical composition and a kit |
US20010034340A1 (en) | 2000-03-20 | 2001-10-25 | American Home Products Corporation | Hormone replacement therapy |
US6245819B1 (en) | 2000-07-21 | 2001-06-12 | Hormos Medical Oy, Ltd. | Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause |
-
2000
- 2000-07-21 US US09/625,199 patent/US6245819B1/en active Active
-
2001
- 2001-02-05 UA UA2003021522A patent/UA74386C2/uk unknown
- 2001-05-02 DE DE60112301T patent/DE60112301T2/de not_active Expired - Lifetime
- 2001-05-02 JP JP2002513454A patent/JP5575351B2/ja not_active Expired - Lifetime
- 2001-05-02 RU RU2003105159/14A patent/RU2268035C2/ru active
- 2001-05-02 DK DK01931746T patent/DK1305014T3/da active
- 2001-05-02 PL PL359506A patent/PL202654B1/pl unknown
- 2001-05-02 EE EEP200300031A patent/EE05344B1/xx unknown
- 2001-05-02 ES ES01931746T patent/ES2241819T3/es not_active Expired - Lifetime
- 2001-05-02 CA CA002416480A patent/CA2416480C/en not_active Expired - Lifetime
- 2001-05-02 BR BR0112659-8A patent/BR0112659A/pt not_active Application Discontinuation
- 2001-05-02 SK SK1607-2002A patent/SK287096B6/sk not_active IP Right Cessation
- 2001-05-02 AT AT01931746T patent/ATE300289T1/de active
- 2001-05-02 MX MXPA03000378A patent/MXPA03000378A/es active IP Right Grant
- 2001-05-02 AU AU2001258449A patent/AU2001258449B2/en not_active Expired
- 2001-05-02 CN CNB018130194A patent/CN1287775C/zh not_active Expired - Lifetime
- 2001-05-02 WO PCT/FI2001/000414 patent/WO2002007718A1/en active IP Right Grant
- 2001-05-02 CZ CZ20030026A patent/CZ299439B6/cs not_active IP Right Cessation
- 2001-05-02 EP EP01931746A patent/EP1305014B1/en not_active Expired - Lifetime
- 2001-05-02 SI SI200130410T patent/SI1305014T1/sl unknown
- 2001-05-02 IL IL153823A patent/IL153823A/en active IP Right Grant
- 2001-05-02 HU HU0301791A patent/HU229361B1/hu unknown
- 2001-05-02 KR KR1020027015576A patent/KR100880564B1/ko active IP Right Grant
- 2001-05-02 NZ NZ524181A patent/NZ524181A/en not_active IP Right Cessation
- 2001-05-02 PT PT01931746T patent/PT1305014E/pt unknown
- 2001-05-02 AU AU5844901A patent/AU5844901A/xx active Pending
-
2002
- 2002-06-06 US US10/162,708 patent/US6984665B2/en not_active Expired - Lifetime
-
2003
- 2003-01-13 ZA ZA200300342A patent/ZA200300342B/en unknown
- 2003-01-17 HR HR20030024A patent/HRP20030024A2/xx not_active Application Discontinuation
- 2003-01-17 BG BG107472A patent/BG65943B1/bg unknown
- 2003-01-20 NO NO20030273A patent/NO329954B1/no not_active IP Right Cessation
- 2003-12-17 HK HK03109192A patent/HK1056694A1/xx not_active IP Right Cessation
-
2005
- 2005-08-11 US US11/201,098 patent/US20050272825A1/en not_active Abandoned
- 2005-10-26 CY CY20051101313T patent/CY1105370T1/el unknown
-
2010
- 2010-07-15 US US12/837,292 patent/US9566252B2/en not_active Expired - Lifetime
-
2012
- 2012-10-25 JP JP2012235543A patent/JP5629746B2/ja not_active Expired - Lifetime
-
2014
- 2014-01-24 US US14/163,757 patent/US20140142195A1/en not_active Abandoned
Also Published As
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