BR0112659A - Processo para o tratamento de secura vaginal ou disfunção sexual em mulheres durante ou depois da menopausa e utilização do composto (diaminoidroxi)toremifeno ou de um sal, éster ou metabolito farmaceuticamente aceitável do mesmo - Google Patents

Processo para o tratamento de secura vaginal ou disfunção sexual em mulheres durante ou depois da menopausa e utilização do composto (diaminoidroxi)toremifeno ou de um sal, éster ou metabolito farmaceuticamente aceitável do mesmo

Info

Publication number
BR0112659A
BR0112659A BR0112659-8A BR0112659A BR0112659A BR 0112659 A BR0112659 A BR 0112659A BR 0112659 A BR0112659 A BR 0112659A BR 0112659 A BR0112659 A BR 0112659A
Authority
BR
Brazil
Prior art keywords
menopause
toremifene
ester
metabolite
compound
Prior art date
Application number
BR0112659-8A
Other languages
English (en)
Inventor
Kaija Halonen
Lauri Kangas
Michael W Degregorio
Original Assignee
Hormos Medical Corp
Tess Diagnostics And Pharmaceu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24504996&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BR0112659(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hormos Medical Corp, Tess Diagnostics And Pharmaceu filed Critical Hormos Medical Corp
Publication of BR0112659A publication Critical patent/BR0112659A/pt

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A61K31/085—Ethers or acetals having an ether linkage to aromatic ring nuclear carbon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/075—Ethers or acetals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/12—Drugs for genital or sexual disorders; Contraceptives for climacteric disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/30—Oestrogens

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Diabetes (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

"PROCESSO PARA O TRATAMENTO DE SECURA VAGINAL OU DISFUNçãO SEXUAL EM MULHERES DURANTE OU DEPOIS DA MENOPAUSA E UTILIZAçãO DO COMPOSTO (DIAMINOIDRóXI) TOREMIFENO OU DE UM SAL, éSTER OU METABOLITO FARMACEUTICAMENTE ACEITáVEL DO MESMO". A presente invenção relaciona-se com um processo para o tratamento de secura vaginal ou disfunção sexual em mulheres durante ou depois da menopausa, o dito processo compreendendo administrar à mulher uma quantidade efetiva do composto (deaminoidróxi) toremifeno ou um sal, ou um éster, ou um metabolito farmaceuticamente aceitável do mesmo.
BR0112659-8A 2000-07-21 2001-05-02 Processo para o tratamento de secura vaginal ou disfunção sexual em mulheres durante ou depois da menopausa e utilização do composto (diaminoidroxi)toremifeno ou de um sal, éster ou metabolito farmaceuticamente aceitável do mesmo BR0112659A (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/625,199 US6245819B1 (en) 2000-07-21 2000-07-21 Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause
PCT/FI2001/000414 WO2002007718A1 (en) 2000-07-21 2001-05-02 Method for the treatment of climacteric disorders in women during or after the menopause

Publications (1)

Publication Number Publication Date
BR0112659A true BR0112659A (pt) 2003-06-24

Family

ID=24504996

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0112659-8A BR0112659A (pt) 2000-07-21 2001-05-02 Processo para o tratamento de secura vaginal ou disfunção sexual em mulheres durante ou depois da menopausa e utilização do composto (diaminoidroxi)toremifeno ou de um sal, éster ou metabolito farmaceuticamente aceitável do mesmo

Country Status (31)

Country Link
US (5) US6245819B1 (pt)
EP (1) EP1305014B1 (pt)
JP (2) JP5575351B2 (pt)
KR (1) KR100880564B1 (pt)
CN (1) CN1287775C (pt)
AT (1) ATE300289T1 (pt)
AU (2) AU2001258449B2 (pt)
BG (1) BG65943B1 (pt)
BR (1) BR0112659A (pt)
CA (1) CA2416480C (pt)
CY (1) CY1105370T1 (pt)
CZ (1) CZ299439B6 (pt)
DE (1) DE60112301T2 (pt)
DK (1) DK1305014T3 (pt)
EE (1) EE05344B1 (pt)
ES (1) ES2241819T3 (pt)
HK (1) HK1056694A1 (pt)
HR (1) HRP20030024A2 (pt)
HU (1) HU229361B1 (pt)
IL (1) IL153823A (pt)
MX (1) MXPA03000378A (pt)
NO (1) NO329954B1 (pt)
NZ (1) NZ524181A (pt)
PL (1) PL202654B1 (pt)
PT (1) PT1305014E (pt)
RU (1) RU2268035C2 (pt)
SI (1) SI1305014T1 (pt)
SK (1) SK287096B6 (pt)
UA (1) UA74386C2 (pt)
WO (1) WO2002007718A1 (pt)
ZA (1) ZA200300342B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL120266A (en) 1996-02-28 2005-05-17 Pfizer Use of estrogen antagonists and estrogen agonists in the preparation of medicaments for inhibiting pathological conditions
US20020013327A1 (en) * 2000-04-18 2002-01-31 Lee Andrew G. Compositions and methods for treating female sexual dysfunction
CA2408399A1 (en) * 2000-05-09 2001-11-15 Nitromed, Inc. Infrared thermography and methods of use
US6245819B1 (en) * 2000-07-21 2001-06-12 Hormos Medical Oy, Ltd. Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause
PT1509215E (pt) * 2002-06-06 2007-01-31 Hormos Medical Ltd Tratamento ou profilaxia da atrofia urogenital e seus sintomas em mulheres
US20060004088A1 (en) * 2002-10-22 2006-01-05 Oct Inc. Furan derivatives for preventing and curing osteoporosis and pharmaceutical compositions containing the same
US20040248989A1 (en) 2003-06-05 2004-12-09 Risto Santti Method for the treatment or prevention of lower urinary tract symptoms
US8236861B2 (en) 2004-02-13 2012-08-07 Hormos Medical Corporation Method for enhancing the bioavailablity of ospemifene
US8642079B2 (en) * 2004-02-23 2014-02-04 Hormos Medical Corporation Solid formulations of ospemifene
US20050187302A1 (en) * 2004-02-23 2005-08-25 Hormos Medical Corporation Method for treatment or prevention of osteoporosis in individuals with high bone turnover
US8758821B2 (en) 2004-05-04 2014-06-24 Hormos Medical Ltd. Oral formulations of ospemifene
ES2391626T3 (es) * 2004-05-04 2012-11-28 Hormos Medical Ltd. Nuevas composiciones orales de ospemifeno
KR100734942B1 (ko) 2007-01-02 2007-07-03 김재현 여성 갱년기 증후군에 유효한 건강기능식품 조성물
PL2121553T3 (pl) 2007-02-14 2012-11-30 Hormos Medical Ltd Sposób wytwarzania cennych terapeutycznie pochodnych trifenylobutenu
US7504530B2 (en) * 2007-02-14 2009-03-17 Hormos Medical Ltd. Methods for the preparation of fispemifene from ospemifene
US20080293683A1 (en) * 2007-05-24 2008-11-27 University Of Kansas Medical Center Hormone Replacement Therapy
RU2535112C2 (ru) * 2012-09-19 2014-12-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Дагестанская государственная медицинская академия министерства здравоохранения и социального развития" Способ лечения климактерических и урогенитальных расстройств у женщин в постменопаузе на фоне гипотириоза
WO2014060639A1 (en) 2012-10-19 2014-04-24 Fermion Oy A process for the preparation of ospemifene
ES2960344T3 (es) 2015-03-10 2024-03-04 Shionogi Inc Dispersiones sólidas que comprenden ospemifeno
CN107530321B (zh) * 2015-03-19 2022-12-30 Gto制药有限责任公司 针对女性性障碍的治疗化合物和治疗形式
RU2636619C1 (ru) * 2017-02-20 2017-11-24 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр акушерства, гинекологии и перинатологии имени академика В.И. Кулакова" Министерства здравоохранения Российской Федерации Способ лечения вагинальной атрофии у женщин в постменопаузе с учетом состояния эпителия и микробиоценоза влагалища

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352699A (en) 1992-04-30 1994-10-04 University Of Massachusetts Medical Center Use of retinioc acid to treat vaginal atrophy
US5461064A (en) * 1993-12-21 1995-10-24 Eli Lilly And Company Methods of inhibiting atrophy of the skin and vagina
GB9418067D0 (en) 1994-09-07 1994-10-26 Orion Yhtymae Oy Triphenylethylenes for the prevention and treatment of osteoporosis
US5747059A (en) 1996-01-11 1998-05-05 Novo Nordisk A/S Atrophy of skin/mucous membrane
GB9604577D0 (en) * 1996-03-04 1996-05-01 Orion Yhtymae Oy Serum cholesterol lowering agent
CO5271697A1 (es) * 2000-01-12 2003-04-30 Pfizer Prod Inc Composiciones y procedimientos para el tratamiento de afecciones que responden a un aumento de testosterona
CN1400904A (zh) 2000-01-28 2003-03-05 恩多研究公司 与雌激素联合的选择性雌激素受体调节剂
US20010034340A1 (en) 2000-03-20 2001-10-25 American Home Products Corporation Hormone replacement therapy
US6245819B1 (en) * 2000-07-21 2001-06-12 Hormos Medical Oy, Ltd. Method for the treatment of vaginal dryness and sexual dysfunction in women during or after the menopause

Also Published As

Publication number Publication date
US6245819B1 (en) 2001-06-12
CZ299439B6 (cs) 2008-07-30
NO329954B1 (no) 2011-01-31
NO20030273L (no) 2003-01-20
NZ524181A (en) 2003-07-25
IL153823A0 (en) 2003-07-31
ES2241819T3 (es) 2005-11-01
AU5844901A (en) 2002-02-05
DE60112301D1 (de) 2005-09-01
DE60112301T2 (de) 2006-05-24
EP1305014A1 (en) 2003-05-02
CN1446085A (zh) 2003-10-01
JP5575351B2 (ja) 2014-08-20
US20140142195A1 (en) 2014-05-22
EE200300031A (et) 2004-10-15
JP2004504345A (ja) 2004-02-12
PL202654B1 (pl) 2009-07-31
US20050272825A1 (en) 2005-12-08
US6984665B2 (en) 2006-01-10
HU229361B1 (en) 2013-11-28
NO20030273D0 (no) 2003-01-20
BG107472A (bg) 2003-11-28
CN1287775C (zh) 2006-12-06
EE05344B1 (et) 2010-10-15
PL359506A1 (en) 2004-08-23
RU2268035C2 (ru) 2006-01-20
AU2001258449B2 (en) 2004-07-29
ZA200300342B (en) 2004-02-13
SK16072002A3 (sk) 2003-06-03
CA2416480C (en) 2009-12-08
EP1305014B1 (en) 2005-07-27
HUP0301791A3 (en) 2008-01-28
US9566252B2 (en) 2017-02-14
DK1305014T3 (da) 2005-08-22
JP2013060445A (ja) 2013-04-04
US20030036566A1 (en) 2003-02-20
US20100280131A1 (en) 2010-11-04
CZ200326A3 (cs) 2003-05-14
WO2002007718A8 (en) 2002-11-14
CY1105370T1 (el) 2010-04-28
HRP20030024A2 (en) 2006-12-31
KR100880564B1 (ko) 2009-01-30
ATE300289T1 (de) 2005-08-15
BG65943B1 (bg) 2010-06-30
CA2416480A1 (en) 2002-01-31
MXPA03000378A (es) 2003-09-22
WO2002007718A1 (en) 2002-01-31
UA74386C2 (uk) 2005-12-15
HUP0301791A2 (hu) 2003-12-29
IL153823A (en) 2008-03-20
PT1305014E (pt) 2005-09-30
JP5629746B2 (ja) 2014-11-26
SK287096B6 (sk) 2009-12-07
SI1305014T1 (sl) 2005-12-31
HK1056694A1 (en) 2004-02-27
KR20030048378A (ko) 2003-06-19

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Legal Events

Date Code Title Description
B25A Requested transfer of rights approved

Owner name: HORMOS MEDICAL CORPORATION (FI)

Free format text: TRANSFERIDO DE: TESS DIAGNOSTICS AND PHARMACEUTICALS, INC.

B06F Objections, documents and/or translations needed after an examination request according [chapter 6.6 patent gazette]

Free format text: DE ACORDO COM ART. 34 " II " DA LPI ( LEI 9279, DE 14/05/96 ) , O EXAME FICA SUSPENSO PARA QUE O REQUERENTE APRESENTE DOCUMENTOS NECESSARIOS A REGULARIZACAO DO PROCESSO E EXAME DO PEDIDO.

B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B09B Patent application refused [chapter 9.2 patent gazette]

Free format text: INDEFIRO O PEDIDO DE ACORDO COM O(S) ARTIGO(S) DA LPI

B12B Appeal against refusal [chapter 12.2 patent gazette]