HUP0103557A2 - Antraciklinszármazék alkalmazása májtumor kezelésére - Google Patents

Antraciklinszármazék alkalmazása májtumor kezelésére

Info

Publication number
HUP0103557A2
HUP0103557A2 HU0103557A HUP0103557A HUP0103557A2 HU P0103557 A2 HUP0103557 A2 HU P0103557A2 HU 0103557 A HU0103557 A HU 0103557A HU P0103557 A HUP0103557 A HU P0103557A HU P0103557 A2 HUP0103557 A2 HU P0103557A2
Authority
HU
Hungary
Prior art keywords
treatment
mmdx
liver tumors
liver tumor
anthracycline derivative
Prior art date
Application number
HU0103557A
Other languages
English (en)
Inventor
David Kerr
Maria Adele Pacciarini
Olga Valota
Original Assignee
Pharmacia & Upjohn S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia & Upjohn S.P.A. filed Critical Pharmacia & Upjohn S.P.A.
Publication of HUP0103557A2 publication Critical patent/HUP0103557A2/hu
Publication of HUP0103557A3 publication Critical patent/HUP0103557A3/hu
Publication of HU229186B1 publication Critical patent/HU229186B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5355—Non-condensed oxazines and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7034—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin
    • A61K31/704—Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a carbocyclic compound, e.g. phloridzin attached to a condensed carbocyclic ring system, e.g. sennosides, thiocolchicosides, escin, daunorubicin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Dermatology (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)

Abstract

A találmány az alábbi képletű (metoxi-morfolino)-doxorubicinnek humánmájtumorok kezelésében történő intrahepaticus beadáshoz formáltgyógyszerkészítmények előállítására történő felhasználására, valamintaz ilyen gyógyszerkészítményekre vonatkozik. A találmány továbbitárgyát képezi egy eljárás humán májtumor kezelésére, amelynek soránegy ilyen kezelést igénylő betegnek terápiásan hatásos mennyiségbenMMDX-et intrahepaticus úton adnak be. Ugyancsak a találmány tárgyátképezi egy eljárás májtumorban szenvedő betegek szisztémás MMDXterhelésének csökkentésére, amelynek során a betegnek az MMDXterápiásan hatásos mennyiségét intrahepaticus úton adják be. Ó
HU0103557A 1998-09-14 1999-08-27 Use of an anthracycline derivative for the treatment of a liver tumor HU229186B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9820012.4A GB9820012D0 (en) 1998-09-14 1998-09-14 Use of an anthracycline derivative for the treatment of a liver tumor
PCT/EP1999/006298 WO2000015203A2 (en) 1998-09-14 1999-08-27 Use of methoxymorpholino doxorubicin for the treatment of a liver tumor

Publications (3)

Publication Number Publication Date
HUP0103557A2 true HUP0103557A2 (hu) 2002-01-28
HUP0103557A3 HUP0103557A3 (en) 2002-12-28
HU229186B1 HU229186B1 (en) 2013-09-30

Family

ID=10838847

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0103557A HU229186B1 (en) 1998-09-14 1999-08-27 Use of an anthracycline derivative for the treatment of a liver tumor

Country Status (26)

Country Link
EP (1) EP1112066B1 (hu)
JP (2) JP5529360B2 (hu)
KR (1) KR100685155B1 (hu)
CN (1) CN1168452C (hu)
AT (1) ATE245029T1 (hu)
AU (1) AU773451B2 (hu)
BR (1) BR9913627A (hu)
CA (1) CA2343120C (hu)
CZ (1) CZ295901B6 (hu)
DE (1) DE69909636T2 (hu)
DK (1) DK1112066T3 (hu)
EA (1) EA004570B1 (hu)
ES (1) ES2203175T3 (hu)
GB (1) GB9820012D0 (hu)
HK (1) HK1050853A1 (hu)
HU (1) HU229186B1 (hu)
ID (1) ID28035A (hu)
IL (2) IL141645A0 (hu)
MY (1) MY124247A (hu)
NO (1) NO329746B1 (hu)
NZ (1) NZ510445A (hu)
PL (1) PL198025B1 (hu)
PT (1) PT1112066E (hu)
TW (1) TWI222868B (hu)
UA (1) UA69423C2 (hu)
WO (1) WO2000015203A2 (hu)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9909925D0 (en) * 1999-04-29 1999-06-30 Pharmacia & Upjohn Spa Combined preparations comprising anthracycline derivatives
AU2003276087A1 (en) * 2002-10-28 2004-05-13 Pharmacia Italia Spa Method for optimizing therapeutic efficacy of nemorubicin
WO2004075904A1 (en) * 2003-02-26 2004-09-10 Pharmacia Italia Spa Method for treating liver cancer by intrahepatic administration of nemorubicin
WO2008138758A1 (en) * 2007-05-11 2008-11-20 Nerviano Medical Sciences S.R.L. Pharmaceutical composition of an anthracycline
JP2016124818A (ja) * 2014-12-26 2016-07-11 日本化薬株式会社 転移性肝癌治療薬及び転移性肝癌の治療方法
PL244818B1 (pl) * 2021-11-03 2024-03-11 Urteste Spolka Z Ograniczona Odpowiedzialnoscia Związek-marker diagnostyczny raka wątroby, sposób wykrywania aktywności enzymatycznej, sposób diagnozowania raka wątroby, zestaw zawierający taki związek oraz związek do zastosowania medycznego

Also Published As

Publication number Publication date
KR100685155B1 (ko) 2007-02-22
NZ510445A (en) 2003-01-31
JP5529360B2 (ja) 2014-06-25
IL141645A (en) 2007-05-15
GB9820012D0 (en) 1998-11-04
PL198025B1 (pl) 2008-05-30
CZ2001895A3 (cs) 2001-08-15
DK1112066T3 (da) 2003-11-03
CZ295901B6 (cs) 2005-11-16
PT1112066E (pt) 2003-11-28
CA2343120A1 (en) 2000-03-23
BR9913627A (pt) 2001-05-22
UA69423C2 (uk) 2004-09-15
HU229186B1 (en) 2013-09-30
EP1112066B1 (en) 2003-07-16
CN1383382A (zh) 2002-12-04
NO20011116L (no) 2001-05-14
WO2000015203A3 (en) 2000-07-20
AU773451B2 (en) 2004-05-27
WO2000015203A2 (en) 2000-03-23
CN1168452C (zh) 2004-09-29
MY124247A (en) 2006-06-30
HUP0103557A3 (en) 2002-12-28
IL141645A0 (en) 2002-03-10
JP2014088398A (ja) 2014-05-15
ID28035A (id) 2001-05-03
DE69909636D1 (de) 2003-08-21
ATE245029T1 (de) 2003-08-15
EA004570B1 (ru) 2004-06-24
NO20011116D0 (no) 2001-03-05
CA2343120C (en) 2009-11-24
EP1112066A2 (en) 2001-07-04
HK1050853A1 (en) 2003-07-11
NO329746B1 (no) 2010-12-13
DE69909636T2 (de) 2004-06-09
AU5742199A (en) 2000-04-03
PL348749A1 (en) 2002-06-03
ES2203175T3 (es) 2004-04-01
EA200100353A1 (ru) 2001-10-22
JP2002524496A (ja) 2002-08-06
TWI222868B (en) 2004-11-01
KR20010075074A (ko) 2001-08-09

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Legal Events

Date Code Title Description
GB9A Succession in title

Owner name: NERVIANO MEDICAL SCIENCES S.R.L., IT

Free format text: FORMER OWNER(S): PHARMACIA & UPJOHN S.P.A., IT

MM4A Lapse of definitive patent protection due to non-payment of fees