HUP0300417A2 - Hajnövesztő kompozíciók és eljárás azok stabilizálására a kristálykiválás gátlásával - Google Patents

Hajnövesztő kompozíciók és eljárás azok stabilizálására a kristálykiválás gátlásával

Info

Publication number
HUP0300417A2
HUP0300417A2 HU0300417A HUP0300417A HUP0300417A2 HU P0300417 A2 HUP0300417 A2 HU P0300417A2 HU 0300417 A HU0300417 A HU 0300417A HU P0300417 A HUP0300417 A HU P0300417A HU P0300417 A2 HUP0300417 A2 HU P0300417A2
Authority
HU
Hungary
Prior art keywords
weight
hair growth
compositions
precipitation
stabilization
Prior art date
Application number
HU0300417A
Other languages
English (en)
Inventor
Taro Horie
Koji Imamura
Susumu Morioka
Rumi Ochiai
Takako Okajima
Original Assignee
Taisho Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taisho Pharmaceutical Co., Ltd. filed Critical Taisho Pharmaceutical Co., Ltd.
Publication of HUP0300417A2 publication Critical patent/HUP0300417A2/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00—Preparations for affecting hair growth
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/34—Alcohols
    • A61K8/345—Alcohols containing more than one hydroxy group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4953—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom containing pyrimidine ring derivatives, e.g. minoxidil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Emergency Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

A találmány hatóanyagként minoxidilt tartalmazó, alacsonyhőmérsékleten is stabil hajnövesztő kompozíciókra és olyan eljárásravonatkozik, amellyel gátolni lehet ezekben a kompozíciókban akristálykiválást. A találmány szerinti hajnövesztő kompozíciók 10-50tömeg%-ban vizet, legalább 3 tömeg%-ban minoxidilt, valamint 8-30tömeg%-ban egy vagy több többértékű alkoholt tartalmaznak, és pH-értékük 5,5 és 6,5 között van. A találmány szerinti eljárással úgygátolják a találmány szerinti hajnövesztő kompozíciókban akristálykiválást, hogy a 10-50 tömeg% vizet és legalább 3 tömeg%minoxidilt tartalmazó elegyekbe belekevernek 8-30 tömeg% mennyiségűtöbbértékű alkoholt, majd az így kapott kompozíciók pH-ját 5,5 és 6,5közötti értékre állítják be. Ó
HU0300417A 2000-04-07 2001-04-05 Hajnövesztő kompozíciók és eljárás azok stabilizálására a kristálykiválás gátlásával HUP0300417A2 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2000106500 2000-04-07
PCT/JP2001/002942 WO2001076541A1 (fr) 2000-04-07 2001-04-05 Compositions stimulant la pousse des cheveux

Publications (1)

Publication Number Publication Date
HUP0300417A2 true HUP0300417A2 (hu) 2003-08-28

Family

ID=18619657

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0300417A HUP0300417A2 (hu) 2000-04-07 2001-04-05 Hajnövesztő kompozíciók és eljárás azok stabilizálására a kristálykiválás gátlásával

Country Status (18)

Country Link
US (2) US20030108500A1 (hu)
EP (1) EP1269973B1 (hu)
JP (2) JP5527787B2 (hu)
KR (1) KR100774074B1 (hu)
CN (1) CN100361644C (hu)
AT (1) ATE305765T1 (hu)
AU (2) AU4473101A (hu)
BR (1) BR0110146A (hu)
CA (1) CA2405452A1 (hu)
DE (1) DE60113822T2 (hu)
ES (1) ES2245980T3 (hu)
HK (1) HK1057708A1 (hu)
HU (1) HUP0300417A2 (hu)
NZ (1) NZ521830A (hu)
RU (1) RU2274440C2 (hu)
TW (1) TWI289459B (hu)
WO (1) WO2001076541A1 (hu)
ZA (1) ZA200208013B (hu)

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AUPO983897A0 (en) 1997-10-17 1997-11-06 Soltec Research Pty Ltd Topical antifungal composition
AUPP310798A0 (en) 1998-04-22 1998-05-14 Soltec Research Pty Ltd Vehicle system for a composition comprising a piperidinopyrimidine derivative
WO2001078662A1 (fr) * 2000-04-07 2001-10-25 Taisho Pharmaceutical Co. Ltd. Compositions de toniques capillaires a action durable
KR100445966B1 (ko) * 2002-06-15 2004-08-25 (주) 아름다운 화장품 액상의 모발 보습영양제 조성물
WO2005067873A1 (en) * 2003-12-22 2005-07-28 Regrowth, Llc Topical solutions comprising high concentrations of piperidinopyrimidine derivatives and methods of use thereof
JP2005206536A (ja) * 2004-01-23 2005-08-04 Kao Corp 育毛剤組成物
US20050163811A1 (en) * 2004-01-23 2005-07-28 Richard Lee Topical solutions comprising high concentrations of piperidinopyrimidine derivatives and methods of use thereof
US8147815B2 (en) * 2005-12-16 2012-04-03 Celmatrix Corporation Topical administration carrier composition and therapeutic formulations comprising same
ES2315115B1 (es) * 2006-07-31 2009-12-30 Desarrollo Biotecnologico, S.L. Nueva solucion capilar concentrada a base de minoxidil.
US8021649B2 (en) 2007-02-22 2011-09-20 Cronk Peter J Continuous spray scalp therapy and dispensing systems for same
US20080206156A1 (en) * 2007-02-22 2008-08-28 Cronk Peter J Continuous spray scalp therapy and dispensing systems for same
ES2454652T3 (es) 2008-03-11 2014-04-11 Basf Se Microcápsulas con liberación inducida por radiación o térmica
JP2009269844A (ja) * 2008-05-02 2009-11-19 Fujifilm Corp 頭髪用組成物
US8729033B2 (en) * 2008-11-03 2014-05-20 Giuliani S.P.A. Therapeutic, dietary or cosmetic use of compounds with specific anti-apoptotic activity toward caspase-3, and compositions containing these compounds
JP5622187B2 (ja) * 2009-09-08 2014-11-12 群泰生物科技股▲ふん▼有限公司 水溶性ミノキシジル組成物
EP2510930A1 (en) 2011-04-15 2012-10-17 Bionanoplus, S.L. Nanoparticles comprising half esters of poly (methyl vinyl ether-co-maleic anhydride) and uses thereof
WO2013078259A2 (en) * 2011-11-25 2013-05-30 Jackson Adrianna Janell Oil compositions and methods for increasing hair growth and/or preventing hair loss
EP2883538A1 (en) * 2012-07-27 2015-06-17 Taisho Pharmaceutical Co., Ltd. Composition for agent for external use
WO2014122436A1 (en) * 2013-02-07 2014-08-14 Cipla House Topical pharmaceutical compositions comprising minoxidil
JP6244101B2 (ja) * 2013-04-24 2017-12-06 ロート製薬株式会社 ミノキシジル含有外用組成物
JP6528194B2 (ja) * 2015-02-06 2019-06-12 ダイヤ製薬株式会社 ミノキシジル含有外用液剤および外用液剤の製造方法
JP6052686B2 (ja) * 2015-02-06 2016-12-27 ダイヤ製薬株式会社 外用液剤
JP2018048105A (ja) * 2016-01-22 2018-03-29 大正製薬株式会社 外用組成物
JP2018048104A (ja) * 2016-01-22 2018-03-29 大正製薬株式会社 外用組成物
JP6880871B2 (ja) * 2016-03-30 2021-06-02 大正製薬株式会社 エアゾール剤
US9962444B2 (en) 2016-09-27 2018-05-08 Shane Malek Pharmacokinetically extended action topical hair growth formulation, and administration method
JP7124435B2 (ja) * 2017-05-18 2022-08-24 大正製薬株式会社 外用組成物
JP2020037517A (ja) * 2017-09-04 2020-03-12 ロート製薬株式会社 ミノキシジルを含有する外用組成物、および、ミノキシジルの析出防止方法
JP2020023467A (ja) * 2018-01-19 2020-02-13 ロート製薬株式会社 外用製剤、液切れ性を改善する方法、および、液切れ性改善剤
JP6628059B2 (ja) * 2018-02-09 2020-01-08 ダイヤ製薬株式会社 ミノキシジル含有外用剤
JP7488634B2 (ja) * 2019-07-10 2024-05-22 ロート製薬株式会社 外用製剤
JP2021134164A (ja) * 2020-02-26 2021-09-13 東亜薬品株式会社 ミノキシジル及びパントテニールエチルエーテルを含有する育毛外用剤、並びにそのパントテニールエチルエーテルの安定化及びミノキシジル等の結晶化抑制方法
BR102021003531A2 (pt) 2021-02-24 2022-08-30 Eurofarma Laboratorios S.A. Composição farmacêutica tópica espumável

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63145217A (ja) * 1986-12-09 1988-06-17 Taisho Pharmaceut Co Ltd 経皮投与組成物
US5030442A (en) * 1987-03-30 1991-07-09 Liposome Technology, Inc. Non-crystalline minoxidil composition
JP2810041B2 (ja) * 1987-09-09 1998-10-15 株式会社資生堂 頭皮・頭髪用養毛料
JP2675111B2 (ja) * 1988-02-18 1997-11-12 ジ・アップジョン・カンパニー ミノキシジルゲル
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JPH06211681A (ja) * 1993-01-12 1994-08-02 Taisho Pharmaceut Co Ltd テストステロン−５α−リダクターゼ阻害剤
FR2700952B1 (fr) * 1993-01-29 1995-03-17 Oreal Nouvelles compositions cosmétiques ou dermopharmaceutiques sous forme de gels aqueux modifiés par addition de microsphères expansées.
US6001812A (en) * 1995-04-28 1999-12-14 Societe L'oreal S.A. Modulating body/cranial hair growth with derivatives of the α-type melanocyte-stimulating hormone
JPH10265343A (ja) * 1997-01-23 1998-10-06 Taisho Pharmaceut Co Ltd 持効性育毛剤
WO1998032417A1 (fr) * 1997-01-23 1998-07-30 Taisho Pharmaceutical Co., Ltd. Tonique capillaire persistant
AU757601B2 (en) * 1998-04-22 2003-02-27 Stiefel Research Australia Pty Ltd Pharmaceutical composition
AUPP310798A0 (en) * 1998-04-22 1998-05-14 Soltec Research Pty Ltd Vehicle system for a composition comprising a piperidinopyrimidine derivative
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US6124362A (en) * 1998-07-17 2000-09-26 The Procter & Gamble Company Method for regulating hair growth
US6482857B1 (en) * 1998-07-17 2002-11-19 The University Of Texas Southwestern Medical Center Compositions which contain triterpenes for regulating hair growth

Also Published As

Publication number Publication date
JPWO2001076541A1 (ja) 2004-01-08
JP5561264B2 (ja) 2014-07-30
NZ521830A (en) 2004-07-30
RU2002126557A (ru) 2004-03-20
ZA200208013B (en) 2003-07-24
AU2001244731B2 (en) 2005-02-17
CN100361644C (zh) 2008-01-16
EP1269973B1 (en) 2005-10-05
WO2001076541A1 (fr) 2001-10-18
RU2274440C2 (ru) 2006-04-20
AU4473101A (en) 2001-10-23
HK1057708A1 (en) 2004-04-16
TWI289459B (en) 2007-11-11
EP1269973A1 (en) 2003-01-02
ATE305765T1 (de) 2005-10-15
US20040204433A1 (en) 2004-10-14
KR100774074B1 (ko) 2007-11-06
DE60113822T2 (de) 2006-08-03
JP5527787B2 (ja) 2014-06-25
BR0110146A (pt) 2003-12-30
EP1269973A4 (en) 2003-07-09
ES2245980T3 (es) 2006-02-01
US20030108500A1 (en) 2003-06-12
DE60113822D1 (de) 2006-02-16
CA2405452A1 (en) 2001-10-18
JP2012025770A (ja) 2012-02-09
CN1434698A (zh) 2003-08-06
KR20020081600A (ko) 2002-10-28

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Legal Events

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FD9A Lapse of provisional protection due to non-payment of fees