ATE238339T1 - Verbindungen zur regulierung der meiose - Google Patents

Verbindungen zur regulierung der meiose

Info

Publication number
ATE238339T1
ATE238339T1 AT97948753T AT97948753T ATE238339T1 AT E238339 T1 ATE238339 T1 AT E238339T1 AT 97948753 T AT97948753 T AT 97948753T AT 97948753 T AT97948753 T AT 97948753T AT E238339 T1 ATE238339 T1 AT E238339T1
Authority
AT
Austria
Prior art keywords
compounds
meiosis
useful
compounds regulating
regulating meiosis
Prior art date
Application number
AT97948753T
Other languages
English (en)
Inventor
Christian Grondahl
Frederik Christian Gronvald
Peter Faarup
Anthony Murray
Jan Lund Ottesen
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Application granted granted Critical
Publication of ATE238339T1 publication Critical patent/ATE238339T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/16—Masculine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/18—Feminine contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Reproductive Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Endocrinology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • General Induction Heating (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Oscillators With Electromechanical Resonators (AREA)
AT97948753T 1996-12-20 1997-12-19 Verbindungen zur regulierung der meiose ATE238339T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK147896 1996-12-20
US4148897P 1997-02-11 1997-02-11
PCT/DK1997/000584 WO1998028323A1 (en) 1996-12-20 1997-12-19 Meiosis regulating compounds

Publications (1)

Publication Number Publication Date
ATE238339T1 true ATE238339T1 (de) 2003-05-15

Family

ID=26065809

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97948753T ATE238339T1 (de) 1996-12-20 1997-12-19 Verbindungen zur regulierung der meiose

Country Status (12)

Country Link
US (3) US6486145B2 (de)
EP (1) EP0946584B1 (de)
JP (1) JP2001506656A (de)
KR (1) KR20000069616A (de)
AT (1) ATE238339T1 (de)
AU (1) AU746878B2 (de)
CA (1) CA2275683A1 (de)
DE (1) DE69721304T2 (de)
HU (1) HUP9904616A3 (de)
IL (1) IL130249A0 (de)
NO (1) NO313144B1 (de)
WO (1) WO1998028323A1 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030004148A1 (en) * 1994-06-23 2003-01-02 Byskov Anne G. Regulation of meiosis
CN1326461A (zh) * 1998-05-13 2001-12-12 诺沃挪第克公司 减数分裂调控化合物
KR20010043558A (ko) 1998-05-13 2001-05-25 한센 핀 베네드, 안네 제헤르, 웨이콥 마리안느 감수분열 조절 화합물
EP1087988A1 (de) * 1998-06-19 2001-04-04 Novo Nordisk A/S Die meiose regulierende verbindungen
AU759344B2 (en) * 1998-12-11 2003-04-10 Akzo Nobel N.V. 22S-hydroxycholesta-8, 14-diene derivatives with meiosis regulating activity
EP1150993A1 (de) * 1999-02-10 2001-11-07 Schering Aktiengesellschaft Ungesättigte cholestan derivate und ihre verwendung zur herstellung von meiose regulierenden medikamente
HUP0200157A3 (en) * 1999-02-24 2002-06-28 Novo Nordisk As Treatment of infertility
JP2002537348A (ja) 1999-02-24 2002-11-05 ノボ ノルディスク アクティーゼルスカブ 不妊症の治療
AU2914800A (en) 1999-03-02 2000-09-21 Akzo Nobel N.V. (androst-5-en-17beta-yl)alkyl sulfoxides and sulfones and their use for control of fertility
DK1163258T3 (da) * 1999-03-09 2003-03-31 Akzo Nobel Nv Derivater af 22R-hydroxycholesta-8, 14-dien til inhiberingen af meiosis
US6902528B1 (en) * 1999-04-14 2005-06-07 Stereotaxis, Inc. Method and apparatus for magnetically controlling endoscopes in body lumens and cavities
RU2263516C2 (ru) * 1999-09-16 2005-11-10 Ново Нордиск А/С Композиция для оплодотворения in vitro
EP1127890A1 (de) 2000-02-22 2001-08-29 Schering Aktiengesellschaft Steroid Derivate mit einem an Ring A des Steroidgerüstes kondensierten Ring zur Regulierung der Meiose
EP1257279A2 (de) * 2000-02-25 2002-11-20 Schering Aktiengesellschaft Verbesserung von implantierungsrate mit ff-mas
WO2001076360A2 (en) * 2000-04-06 2001-10-18 Novo Nordisk A/S Synchronization of the cytoplasmatic and the nuclear maturation of oocytes in vitro
DE60225117T2 (de) * 2001-02-06 2009-02-26 Novo Nordisk A/S Behältnis mit niedrigem sauerstoffgehalt, das ff-mas enthält
US6988613B2 (en) 2001-02-06 2006-01-24 Novo Nordisk A/S Composition for IVF
EP1245572A1 (de) 2001-03-26 2002-10-02 Schering Aktiengesellschaft Aminosterol-Verbindungen, ihre Verwendung zur Herstellung Meiose-regulierender Medikamenten und ein Vefahren zu ihrer Herstellung
US8969543B2 (en) * 2003-04-03 2015-03-03 Bioneer Corporation SiRNA-hydrophilic polymer conjugates for intracellular delivery of siRNA and method thereof
US20080312673A1 (en) * 2007-06-05 2008-12-18 Viswanathan Raju R Method and apparatus for CTO crossing
US9447139B2 (en) 2010-04-09 2016-09-20 The Research Foundation Of State University Of New York Ship inhibitors and uses thereof

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1224738B (de) 1960-12-29 1966-09-15 Takeda Chemical Industries Ltd Verfahren zur Herstellung von Cholestan-3, 5, 6-triol-3-estern oder -3, 6-diestern soowie von deren Salzen
DE1183079B (de) 1961-11-27 1964-12-10 Vismara Francesco Spa Verfahren zur Herstellung von gesaettigten 4-Hydroxy-3-keto-5alpha-steroiden
CH470374A (de) 1965-09-24 1969-03-31 Hoffmann La Roche Verfahren zur Herstellung von Steroiden
DE1593492A1 (de) 1966-01-29 1970-07-16 Schering Ag 6-Ketosteroide aus 20-Formyl-6-keto-Steroide
IL38540A0 (en) 1971-01-18 1972-03-28 Dauten Sa Method for the extraction of insect moulting steroid hormones
ZA725157B (en) 1971-07-29 1973-04-25 Dauten Sa New steroid of insecticide action and process for its production
US4670190A (en) 1973-01-10 1987-06-02 Hesse Robert H 1-α-hydroxy vitamin D compounds and process for preparing same
DE2409971C3 (de) 1973-03-02 1978-03-23 Eisai Co., Ltd., Tokio 5-Cholestenderivate und Verfahren zu ihrer Herstellung
IL41923A (en) 1973-04-01 1978-08-31 Yeda Res & Dev Preparation of hydroxylated derivatives of cholestanol and some such compounds
US3931403A (en) 1973-05-25 1976-01-06 Intellectual Property Development Corporation Antimicrobial compositions
US3887545A (en) 1973-11-12 1975-06-03 Hoffmann La Roche Synthesis of 1{60 -hydroxylated cholesterol derivatives
JPS5119752A (en) 1974-08-07 1976-02-17 Masayuki Ishikawa 1 arufua* 2 arufuaa jihidorokishikorekarushifuerooruno seiho
IL45897A (en) 1974-10-22 1978-12-17 Yeda Res & Dev Process for the preparation of 1 hydroxy-provitamin d3
JPS6039278B2 (ja) 1977-05-23 1985-09-05 中外製薬株式会社 ステロイド誘導体
CA1138859A (en) 1979-02-15 1983-01-04 Teijin Limited 25-hydroxy-24-oxocholestane derivatives and preparation thereof
US4230626A (en) 1979-07-30 1980-10-28 G. D. Searle & Co. 25-Halocholest-5-ene-3β,22-diols and esters thereof
US4254045A (en) 1980-04-21 1981-03-03 Wisconsin Alumni Research Foundation 1α-Hydroxy-2β-fluorocholecalciferol
GB2089811B (en) 1980-09-22 1984-09-26 Wisconsin Alumni Res Found 23,25-dihydroxyvitamin d3
EP0063678B1 (de) 1981-04-29 1985-08-21 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Verfahren zur Herstellung von Cholesterinderivaten und Zwischenprodukte dafür
US4329295A (en) 1981-06-29 1982-05-11 G. D. Searle & Co. 24-Cyclopropylcholene-3β, 22-diols and esters thereof
US4348328A (en) 1981-11-09 1982-09-07 G.D. Searle & Co. 25-Substituted-5α-cholestane-3β,22S-diol
US4871727A (en) 1987-12-21 1989-10-03 Merck & Co, Inc. Anti-inflammatory and antidegenerative compounds isolated from L-681,512
JPH0749435B2 (ja) 1988-07-04 1995-05-31 帝人株式会社 １α，３β，２４−トリヒドロキシ−△▲上５▼−ステロイド類の製造方法
US5716777A (en) * 1994-06-23 1998-02-10 Novo Nordisk A/S Regulation of meiosis using sterols
AU717180B2 (en) * 1995-03-06 2000-03-16 Novo Nordisk A/S Stimulation of meiosis

Also Published As

Publication number Publication date
AU746878B2 (en) 2002-05-02
US20010005757A1 (en) 2001-06-28
DE69721304D1 (de) 2003-05-28
NO993009D0 (no) 1999-06-18
US20030032824A1 (en) 2003-02-13
JP2001506656A (ja) 2001-05-22
KR20000069616A (ko) 2000-11-25
US6759400B2 (en) 2004-07-06
HUP9904616A2 (hu) 2000-06-28
US20050004382A1 (en) 2005-01-06
EP0946584A1 (de) 1999-10-06
NO313144B1 (no) 2002-08-19
HUP9904616A3 (en) 2001-02-28
AU7878998A (en) 1998-07-17
EP0946584B1 (de) 2003-04-23
NO993009L (no) 1999-08-19
IL130249A0 (en) 2000-06-01
CA2275683A1 (en) 1998-07-02
DE69721304T2 (de) 2004-03-04
US6486145B2 (en) 2002-11-26
WO1998028323A1 (en) 1998-07-02

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Legal Events

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