HUP0203655A2 - Telítetlen 14,15-ciklopropano-androsztánok, előállításukat szolgáló eljárás és ezen vegyületeket tartalmazó gyógyszerészeti készítmények - Google Patents

Telítetlen 14,15-ciklopropano-androsztánok, előállításukat szolgáló eljárás és ezen vegyületeket tartalmazó gyógyszerészeti készítmények

Info

Publication number
HUP0203655A2
HUP0203655A2 HU0203655A HUP0203655A HUP0203655A2 HU P0203655 A2 HUP0203655 A2 HU P0203655A2 HU 0203655 A HU0203655 A HU 0203655A HU P0203655 A HUP0203655 A HU P0203655A HU P0203655 A2 HUP0203655 A2 HU P0203655A2
Authority
HU
Hungary
Prior art keywords
androstanes
cyclopropane
unsaturated
compounds
production
Prior art date
Application number
HU0203655A
Other languages
English (en)
Inventor
Walter Elger
Günter Kaufmann
Sven Ring
Original Assignee
Jenapharm Gmbh & Co. Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Jenapharm Gmbh & Co. Kg filed Critical Jenapharm Gmbh & Co. Kg
Publication of HUP0203655A2 publication Critical patent/HUP0203655A2/hu
Publication of HUP0203655A3 publication Critical patent/HUP0203655A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
    • C07J53/002—Carbocyclic rings fused
    • C07J53/004—3 membered carbocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/08—Drugs for genital or sexual disorders; Contraceptives for gonadal disorders or for enhancing fertility, e.g. inducers of ovulation or of spermatogenesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/34—Gestagens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Endocrinology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

A találmány tárgya gyógyszerészeti hormonkészítmények, amelyekorálisan adagolhatók, kombinált ösztrogén-progesztogén keverékbőlállnak, amelyek lehetővé teszik egy ösztrogén komponens 0,3-3 mgközötti dózisban történő és egy 19-norprogeszteron-származékprogesztogén komponens 0,3-1 ,5 mg közötti dózisban történő egyidejűadagolását egy vagy több nemtoxikus, inert, gyógyszerészetilegalkalmazható hordozóanyaggal együtt vagy azzal összekeverve. Ó
HU0203655A 1999-12-08 2000-11-21 Unsaturated 14,15-cyclopropane-androstanes, a method for their production and pharmaceutical compositions containing these compounds HUP0203655A3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19959696A DE19959696A1 (de) 1999-12-08 1999-12-08 Ungesättigte 14,15-Cyclopropano-Androstane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
PCT/EP2000/011557 WO2001042275A1 (de) 1999-12-08 2000-11-21 Ungesättigte 14,15-cyclopropano-androstane, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische zusammensetzungen

Publications (2)

Publication Number Publication Date
HUP0203655A2 true HUP0203655A2 (hu) 2003-03-28
HUP0203655A3 HUP0203655A3 (en) 2004-07-28

Family

ID=7932216

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0203655A HUP0203655A3 (en) 1999-12-08 2000-11-21 Unsaturated 14,15-cyclopropane-androstanes, a method for their production and pharmaceutical compositions containing these compounds

Country Status (26)

Country Link
US (2) USRE39862E1 (hu)
EP (1) EP1235850B1 (hu)
JP (1) JP3793088B2 (hu)
KR (1) KR100468341B1 (hu)
CN (1) CN1205219C (hu)
AT (1) ATE275576T1 (hu)
AU (1) AU774384B2 (hu)
BG (1) BG106861A (hu)
BR (1) BR0016737A (hu)
CA (1) CA2393758C (hu)
CZ (1) CZ20022005A3 (hu)
DE (2) DE19959696A1 (hu)
DK (1) DK1235850T3 (hu)
EE (1) EE200200302A (hu)
ES (1) ES2226949T3 (hu)
HU (1) HUP0203655A3 (hu)
IL (2) IL150082A0 (hu)
MX (1) MXPA02005644A (hu)
NO (1) NO323376B1 (hu)
PL (1) PL356061A1 (hu)
PT (1) PT1235850E (hu)
RU (1) RU2244718C2 (hu)
SI (1) SI1235850T1 (hu)
SK (1) SK8092002A3 (hu)
WO (1) WO2001042275A1 (hu)
ZA (1) ZA200205362B (hu)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10104327A1 (de) * 2001-01-24 2002-07-25 Schering Ag 11beta-Halogensteroide, deren Herstellung und Verwendung zur Herstellung von Arzneimitteln sowie 11beta-Halogensteroide enthaltende pharmazeutische Präparate

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE31269C (de) * B.GERVAIS in Montmorillon Vienne, Frankreich Transportable Brauerei für Kleinbetrieb
DE33136C (de) * J. KENDAL und M. LAVAL in London Uhr mit zwei Zifferblättern und dazu gehörigem Zeigerstellwerk
NL110102C (hu) * 1956-03-26
CH376097A (de) * 1956-04-23 1964-03-31 Farmaceutici Italia Verfahren zur Herstellung von 4-Halogen-3-keto- 4-steroiden
US2895969A (en) * 1957-09-23 1959-07-21 Syntex Sa Cyclopentanophenanthrene derivatives
GB839908A (en) * 1957-12-24 1960-06-29 Farmaceutici Italia 4,17ª‡-dihydroxy progesterone and its esters and the preparation thereof
GB874572A (en) * 1959-02-18 1961-08-10 Farmaceutici Italia A method for the production of new ketosteroid compounds
GB928714A (en) * 1961-02-10 1963-06-12 Farmaceutici Italia Process for the preparation of 4-hydroxy-3-keto-í¸-steroids
GB991804A (en) * 1962-03-13 1965-05-12 Piero Gomarasca New derivatives of cyclopentanophenanthrene and processes for their preparation
US3239512A (en) * 1964-08-04 1966-03-08 Syntex Corp 17-tetrahydropyranylether of 4-chlorotestosterone
DE19537626A1 (de) * 1995-10-10 1997-04-17 Jenapharm Gmbh Steroide mit einer 14, 15-Methylengruppe
DE19827523A1 (de) * 1998-06-22 1999-12-23 Jenapharm Gmbh Ungesättigte 14,15-Cyclopropano-Androstane, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Präparate

Also Published As

Publication number Publication date
BR0016737A (pt) 2002-11-05
NO20022712D0 (no) 2002-06-07
AU774384B2 (en) 2004-06-24
WO2001042275A1 (de) 2001-06-14
DE50007708D1 (de) 2004-10-14
EP1235850A1 (de) 2002-09-04
IL150082A0 (en) 2002-12-01
ZA200205362B (en) 2003-10-06
BG106861A (bg) 2003-02-28
IL150082A (en) 2007-05-15
JP2003516416A (ja) 2003-05-13
CN1205219C (zh) 2005-06-08
US6710039B1 (en) 2004-03-23
CZ20022005A3 (cs) 2002-10-16
CA2393758C (en) 2007-06-12
RU2244718C2 (ru) 2005-01-20
PT1235850E (pt) 2005-01-31
CN1433425A (zh) 2003-07-30
NO323376B1 (no) 2007-04-16
NO20022712L (no) 2002-06-07
ES2226949T3 (es) 2005-04-01
HUP0203655A3 (en) 2004-07-28
EE200200302A (et) 2003-06-16
KR100468341B1 (ko) 2005-01-27
JP3793088B2 (ja) 2006-07-05
SK8092002A3 (en) 2003-05-02
DE19959696A1 (de) 2001-06-21
USRE39862E1 (en) 2007-09-25
DK1235850T3 (da) 2005-01-17
PL356061A1 (en) 2004-06-14
CA2393758A1 (en) 2001-06-14
MXPA02005644A (es) 2002-12-13
AU1703801A (en) 2001-06-18
ATE275576T1 (de) 2004-09-15
SI1235850T1 (en) 2005-04-30
KR20030028448A (ko) 2003-04-08
EP1235850B1 (de) 2004-09-08

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