HUP0202021A2 - Ambroxoltartalmú szopogatós tabletta - Google Patents

Ambroxoltartalmú szopogatós tabletta

Info

Publication number
HUP0202021A2
HUP0202021A2 HU0202021A HUP0202021A HUP0202021A2 HU P0202021 A2 HUP0202021 A2 HU P0202021A2 HU 0202021 A HU0202021 A HU 0202021A HU P0202021 A HUP0202021 A HU P0202021A HU P0202021 A2 HUP0202021 A2 HU P0202021A2
Authority
HU
Hungary
Prior art keywords
tablet
amount
ambroxol
talc
subject
Prior art date
Application number
HU0202021A
Other languages
English (en)
Inventor
Holger Hans-Hermann Heydt
Frieder März
Horst Schmitt
Original Assignee
Boehringer Ingelheim International Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=7914872&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HUP0202021(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Boehringer Ingelheim International Gmbh. filed Critical Boehringer Ingelheim International Gmbh.
Publication of HUP0202021A2 publication Critical patent/HUP0202021A2/hu
Publication of HUP0202021A3 publication Critical patent/HUP0202021A3/hu
Publication of HU229040B1 publication Critical patent/HU229040B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2009—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/10—Expectorants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2031—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Dry Formation Of Fiberboard And The Like (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Confectionery (AREA)
  • Chemical And Physical Treatments For Wood And The Like (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Jellies, Jams, And Syrups (AREA)
  • Fats And Perfumes (AREA)
  • Cosmetics (AREA)

Abstract

A találmány tárgyát ambroxoltartalmú olyan szopogatós tabletta képezi,amely mátrixanyagként egy cukoralkoholt, előnyösen szorbitot;gyógyszerészetileg elfogadható rétegszilikátként talkumot; egy 3500 és20000 közötti, előnyösen 6000 molekulatömegű polietilénglikolt,édesítőszerként a szacharin nátriumsóját; aromaanyagkéntborsmentaaromát tartalmaz. Az 1,5 g össztömegű tablettában a hatóanyagambroxol-hidroklorid mennyisége 1 és 50 mg között, a talkum mennyisége5 és 100mg között van. A többi segéd-, illetve ízesítőanyag mennyiségenem kritikus. A találmány tárgyát képezi továbbá a fenti szopogatóstabletta előállítására szolgáló, a komponensek ismert eljárásokszerinti összekeveréséből álló eljárás és a tablettának váladékoldótulajdonságú gyógyszer előállítására való alkalmazása is. A találmányszerinti tabletta nem tapad a tablettázó eszközökre és a bomlástermék-tartalom még hosszabb ideig tartó tárolás esetén is a kimutatási határalatt van. Ó
HU0202021A 1999-07-20 2000-07-07 Ambroxol-containing lozenge HU229040B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19933148A DE19933148A1 (de) 1999-07-20 1999-07-20 Ambroxolhaltige Lutschtablette
PCT/EP2000/006437 WO2001005378A1 (de) 1999-07-20 2000-07-07 Ambroxolhaltige lutschtablette

Publications (3)

Publication Number Publication Date
HUP0202021A2 true HUP0202021A2 (hu) 2002-11-28
HUP0202021A3 HUP0202021A3 (en) 2004-05-28
HU229040B1 HU229040B1 (en) 2013-07-29

Family

ID=7914872

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0202021A HU229040B1 (en) 1999-07-20 2000-07-07 Ambroxol-containing lozenge

Country Status (33)

Country Link
US (1) US6663889B1 (hu)
EP (2) EP1352646A3 (hu)
JP (1) JP3776041B2 (hu)
KR (1) KR100743846B1 (hu)
CN (1) CN1164263C (hu)
AT (1) ATE246493T1 (hu)
AU (1) AU776906B2 (hu)
BG (1) BG65503B1 (hu)
BR (1) BRPI0012553B8 (hu)
CA (1) CA2379314C (hu)
CZ (1) CZ301981B6 (hu)
DE (2) DE19933148A1 (hu)
DK (1) DK1200070T3 (hu)
EA (1) EA004044B1 (hu)
EE (1) EE04797B1 (hu)
ES (1) ES2173823T3 (hu)
HK (1) HK1045946B (hu)
HR (1) HRP20020050B1 (hu)
HU (1) HU229040B1 (hu)
IL (2) IL147261A0 (hu)
ME (1) MEP36808A (hu)
MX (1) MXPA02000546A (hu)
NO (1) NO331306B1 (hu)
NZ (1) NZ516987A (hu)
PL (1) PL197175B1 (hu)
PT (1) PT1200070E (hu)
RS (1) RS50246B (hu)
SI (1) SI1200070T1 (hu)
SK (1) SK284290B6 (hu)
TR (1) TR200200106T2 (hu)
UA (1) UA73313C2 (hu)
WO (1) WO2001005378A1 (hu)
ZA (1) ZA200200384B (hu)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10125883A1 (de) 2001-05-28 2002-12-12 Serumwerk Bernburg Ag Arzneimittel enthaltend einen Effektor des Glutathionmetabolismus zusammen mit alpha-Liponsäure im Rahmen der Nierenersatztherapie
DE10208313A1 (de) * 2002-02-27 2003-09-11 Boehringer Ingelheim Pharma Ambroxol für die Behandlung von schmerzhaften Zuständen im Mund und Rachenraum
US20030166732A1 (en) * 2002-02-27 2003-09-04 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol for the treatment of painful conditions in the mouth and pharyngeal cavity
US20050075403A1 (en) * 2003-10-02 2005-04-07 Boehringer Ingelheim Pharma Gmbh & Co. Kg Ambroxol for the treatment of inflammation in the pharynx
ITMI20032463A1 (it) * 2003-12-16 2005-06-17 Advance Holdings Ltd Soluzione acquosa concentrata a base di ambroxolo
GB0409104D0 (en) * 2004-04-23 2004-05-26 Norgine Europe Bv Compressed pharmaceutical compositions
DE102004021992A1 (de) * 2004-05-03 2005-11-24 Boehringer Ingelheim Pharma Gmbh & Co. Kg Topische Zubereitung enthaltend Ambroxol
DE102005018561A1 (de) * 2005-04-21 2006-11-02 Giesecke & Devrient Gmbh Verfahren zum Betreiben eines Systems mit einem tragbaren Datenträger und einem Endgerät
DE102010009369A1 (de) 2010-02-25 2011-08-25 Boehringer Ingelheim International GmbH, 55218 Kindergesicherte Verpackung für Ambroxolhaltige Lutschtabletten
AR084537A1 (es) 2010-12-23 2013-05-22 Advance Holdings Ltd Solucion acuosa de ambroxol
JP6320931B2 (ja) 2011-12-22 2018-05-09 セントジーン アイピー ゲーエムベーハー リソソーム酵素を再構成する能力を有する化合物ならびにアンブロキソールおよび／またはアンブロキソールの誘導体の組み合わせ
CN115607531A (zh) 2016-11-14 2023-01-17 王明武 用于治疗眼表疾病的制剂
MX2017014725A (es) * 2017-11-16 2019-05-17 Productos Farm S A De C V Dropropizina en combinacion con ambroxol en la forma farmaceutica de jarabe y tabletas.

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3034975C2 (de) * 1980-09-17 1986-11-27 Dr. Karl Thomae Gmbh, 7950 Biberach Arzneimittelkombination zur Behandlung infektiöser Atemwegerkrankungen
EP0138020B1 (de) * 1983-09-17 1992-06-03 Dr. Karl Thomae GmbH Antiadhäsive Prophylactica und Arzneimittel enthaltend ein sekretolytisch wirksames Benzylaminderivat
IT1252185B (it) * 1991-12-11 1995-06-05 Therapicon Srl Preparazioni farmaceutiche a liberazione programmata
DE4420735C2 (de) * 1994-06-15 1996-09-05 Allphamed Arzneimittel Gmbh Verfahren zur Herstellung mechanisch stabiler, sich mit hoher Auflösegeschwindigkeit auszeichnender Brausetabletten
DE19648576C2 (de) * 1996-11-23 1999-08-12 Lohmann Therapie Syst Lts Lutschtablette zur modifizierten Freisetzung von Wirkstoffen im Gastrointestinaltrakt

Also Published As

Publication number Publication date
EE04797B1 (et) 2007-04-16
AU776906B2 (en) 2004-09-23
DE19933148A1 (de) 2001-01-25
YU3802A (sh) 2004-09-03
KR100743846B1 (ko) 2007-08-02
UA73313C2 (uk) 2005-07-15
BR0012553B1 (pt) 2014-05-27
ZA200200384B (en) 2002-10-30
PL197175B1 (pl) 2008-03-31
RS50246B (sr) 2009-07-15
SK812002A3 (en) 2002-06-04
SI1200070T1 (en) 2003-12-31
BG65503B1 (bg) 2008-10-31
EE200200027A (et) 2003-04-15
HK1045946B (zh) 2005-01-28
DK1200070T3 (da) 2003-10-06
BRPI0012553B8 (pt) 2021-05-25
NO331306B1 (no) 2011-11-21
ES2173823T3 (es) 2004-04-16
JP3776041B2 (ja) 2006-05-17
EA004044B1 (ru) 2003-12-25
PL352276A1 (en) 2003-08-11
US6663889B1 (en) 2003-12-16
PT1200070E (pt) 2003-12-31
EP1200070A1 (de) 2002-05-02
NO20020274D0 (no) 2002-01-18
DE50003209D1 (de) 2003-09-11
EP1352646A3 (de) 2004-01-07
MEP36808A (en) 2011-02-10
HU229040B1 (en) 2013-07-29
CZ20014633A3 (cs) 2002-03-13
EA200200091A1 (ru) 2002-06-27
BG106316A (en) 2002-08-30
NZ516987A (en) 2003-08-29
CA2379314C (en) 2007-09-11
HRP20020050B1 (en) 2004-06-30
ATE246493T1 (de) 2003-08-15
EP1200070B1 (de) 2003-08-06
CN1164263C (zh) 2004-09-01
WO2001005378A1 (de) 2001-01-25
IL147261A0 (en) 2002-08-14
SK284290B6 (sk) 2005-01-03
MXPA02000546A (es) 2002-07-30
CA2379314A1 (en) 2001-01-25
BR0012553A (pt) 2002-04-16
ES2173823T1 (es) 2002-11-01
HK1045946A1 (en) 2002-12-20
HUP0202021A3 (en) 2004-05-28
JP2003522125A (ja) 2003-07-22
EP1352646A2 (de) 2003-10-15
NO20020274L (no) 2002-03-13
KR20020012316A (ko) 2002-02-15
CN1364075A (zh) 2002-08-14
HRP20020050A2 (en) 2003-06-30
IL147261A (en) 2006-12-31
TR200200106T2 (tr) 2002-07-22
CZ301981B6 (cs) 2010-08-25
AU6269900A (en) 2001-02-05

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