HUP0103433A3 - Novel isoxazolinone antibacterial agents, their use and process for preparation the compounds - Google Patents
Novel isoxazolinone antibacterial agents, their use and process for preparation the compoundsInfo
- Publication number
- HUP0103433A3 HUP0103433A3 HU0103433A HUP0103433A HUP0103433A3 HU P0103433 A3 HUP0103433 A3 HU P0103433A3 HU 0103433 A HU0103433 A HU 0103433A HU P0103433 A HUP0103433 A HU P0103433A HU P0103433 A3 HUP0103433 A3 HU P0103433A3
- Authority
- HU
- Hungary
- Prior art keywords
- compounds
- preparation
- antibacterial agents
- novel
- isoxazolinone antibacterial
- Prior art date
Links
- JGRCHNVLXORPNM-UHFFFAOYSA-N 1,2-oxazol-4-one Chemical compound O=C1CON=C1 JGRCHNVLXORPNM-UHFFFAOYSA-N 0.000 title 1
- 239000003242 anti bacterial agent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D261/00—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings
- C07D261/02—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings
- C07D261/06—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members
- C07D261/10—Heterocyclic compounds containing 1,2-oxazole or hydrogenated 1,2-oxazole rings not condensed with other rings having two or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D261/12—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9757498P | 1998-08-24 | 1998-08-24 | |
| PCT/US1999/019265 WO2000010566A1 (fr) | 1998-08-24 | 1999-08-23 | Nouveaux agents antibacteriens a base d'isoxazolinone |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| HUP0103433A2 HUP0103433A2 (hu) | 2002-01-28 |
| HUP0103433A3 true HUP0103433A3 (en) | 2002-08-28 |
Family
ID=22264103
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HU0103433A HUP0103433A3 (en) | 1998-08-24 | 1999-08-23 | Novel isoxazolinone antibacterial agents, their use and process for preparation the compounds |
Country Status (22)
| Country | Link |
|---|---|
| EP (1) | EP1107756A4 (fr) |
| JP (1) | JP2002523369A (fr) |
| KR (1) | KR20010072945A (fr) |
| CN (1) | CN1314813A (fr) |
| AR (1) | AR020250A1 (fr) |
| AU (1) | AU748750B2 (fr) |
| BR (1) | BR9913225A (fr) |
| CA (1) | CA2341271A1 (fr) |
| CO (1) | CO5160266A1 (fr) |
| CZ (1) | CZ2001669A3 (fr) |
| HU (1) | HUP0103433A3 (fr) |
| ID (1) | ID27690A (fr) |
| IL (1) | IL141542A0 (fr) |
| NO (1) | NO20010916L (fr) |
| NZ (1) | NZ509867A (fr) |
| PE (1) | PE20001063A1 (fr) |
| PL (1) | PL346267A1 (fr) |
| TR (1) | TR200100672T2 (fr) |
| TW (1) | TW572757B (fr) |
| UY (1) | UY25677A1 (fr) |
| WO (1) | WO2000010566A1 (fr) |
| ZA (1) | ZA200101505B (fr) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6465456B2 (en) | 2000-06-29 | 2002-10-15 | Bristol-Myers Squibb Company | Isoxazolinone antibacterial agents |
| JP2002020366A (ja) * | 2000-07-05 | 2002-01-23 | Sumitomo Seika Chem Co Ltd | アルキルチオフェニル酢酸類の製造方法 |
| PE20030044A1 (es) | 2000-11-17 | 2003-02-09 | Upjohn Co | Isoxazolinonas biciclicas de formula i |
| PE20020689A1 (es) | 2000-11-17 | 2002-08-03 | Upjohn Co | Oxazolidinonas con un heterociclo de 6 o 7 miembros unidos con enlace anular al benceno |
| US6861433B2 (en) | 2000-12-15 | 2005-03-01 | Pharmacia & Upjohn Company | Oxazolidinone photoaffinity probes |
| US6689769B2 (en) | 2000-12-21 | 2004-02-10 | Pharmacia & Upjohn Company | Antimicrobial quinolone derivatives and use of the same to treat bacterial infections |
| ES2180456B1 (es) * | 2001-07-20 | 2004-05-01 | Laboratorios S.A.L.V.A.T., S.A. | Isoxazoles sustituidos y su utilizacion como antibioticos. |
| WO2003031443A1 (fr) | 2001-10-04 | 2003-04-17 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Antibiotiques a action duale renfermant une oxazolidinone et une quinolone ou une fraction de naphthyridinone |
| US7022705B2 (en) | 2001-10-25 | 2006-04-04 | Astrazeneca Ab | Isoxazoline derivatives useful as antimicrobials |
| US6875784B2 (en) | 2002-10-09 | 2005-04-05 | Pharmacia & Upjohn Company | Antimibicrobial [3.1.0.] bicyclic oxazolidinone derivatives |
| US7105547B2 (en) | 2002-10-10 | 2006-09-12 | Pharmacia And Upjohn Company | Antimicrobial 1-aryl dihydropyridone compounds |
| EP1594865A2 (fr) * | 2003-02-07 | 2005-11-16 | Warner-Lambert Company LLC | Agents antibacteriens |
| DE602004014361D1 (de) | 2003-04-30 | 2008-07-24 | Morphochem Ag Komb Chemie | Verwendung von oxazolidinon-chinolin-hybrid-antibiotika zur behandlung von anthrax und anderen infektionen |
| JP2007525468A (ja) * | 2003-06-03 | 2007-09-06 | リブ−エックス ファーマシューティカルズ，インコーポレイテッド | スルホンアミド化合物ならびにその製造方法および使用方法 |
| US8324398B2 (en) | 2003-06-03 | 2012-12-04 | Rib-X Pharmaceuticals, Inc. | Process for the synthesis of biaryl oxazolidinones |
| TWI378092B (en) | 2003-06-03 | 2012-12-01 | Rib X Pharmaceuticals Inc | Biaryl heterocyclic compounds and methods of making and using the same |
| EP1664001A2 (fr) * | 2003-07-29 | 2006-06-07 | Rib-X Pharmaceuticals, Inc. | Composes contenant des biarylamines heterocycliques, des amides et du soufre, et procedes de production et d'utilisation de ces composes |
| DE10340485B4 (de) * | 2003-09-03 | 2015-05-13 | Morphochem AG Aktiengesellschaft für kombinatorische Chemie | Verfahren zur Herstellung von Oxazolidinon-Chinolon Hybriden |
| US7304050B2 (en) * | 2003-09-16 | 2007-12-04 | Pfizer Inc. | Antibacterial agents |
| EP1713785A1 (fr) | 2003-12-17 | 2006-10-25 | Rib-X Pharmaceuticals, Inc. | Composes heterocycliques de biaryle halogenes et methodes de fabrication et d'utilisation |
| ES2310299T5 (es) | 2003-12-18 | 2014-02-10 | Morphochem Aktiengesellschaft für kombinatorische Chemie | Antibióticos híbridos a base de oxazolidinona-quinolona |
| US8158797B2 (en) | 2003-12-18 | 2012-04-17 | Morphochem Aktiengesellschaft Fur Kombinatorische Chemie | Oxazolidinone-quinolone hybrid antibiotics |
| WO2005082900A2 (fr) * | 2004-01-28 | 2005-09-09 | Pharmacia & Upjohn Company Llc | Amidoxines d'oxazolidinone utilisees en tant qu'agents antibacteriens |
| JP5534497B2 (ja) | 2005-06-08 | 2014-07-02 | メリンタ セラピューティクス，インコーポレイテッド | トリアゾール類の合成方法 |
| AT503354B1 (de) * | 2006-02-22 | 2008-07-15 | Dsm Fine Chem Austria Gmbh | Verfahren zur herstellung von 3,4-disubstituierten phenylessigsäuren, sowie neue zwischenverbindungen |
| JP4518066B2 (ja) * | 2006-10-25 | 2010-08-04 | 宇部興産株式会社 | ジアルコキシニトリル誘導体及びその製法 |
| CN110423610B (zh) * | 2019-08-29 | 2023-05-12 | 浙江理工大学 | 一种检测双光子汞离子荧光探针及其制备方法与使用方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2045049A1 (de) * | 1970-09-11 | 1972-03-23 | Dr Karl Thomae GmbH, 7950 Biberach | Neue Nitrofurandenvate und Ver fahren zu ihrer Herstellung |
| US4000155A (en) * | 1975-12-11 | 1976-12-28 | Eli Lilly And Company | Herbicidal 2-methyl-4-phenyl-5-pyrazolinones[and isoxazolinones] |
| RU2119484C1 (ru) * | 1992-12-08 | 1998-09-27 | Дзе Апджон Компани | Тропонзамещенный фенилоксазолидинон или его фармацевтически приемлемые соли или гидраты |
| ATE229014T1 (de) * | 1995-09-15 | 2002-12-15 | Upjohn Co | Alpha,beta-gesättigte und -ungesättigte 3-aryl-5- aminomethyl-butyrolactone antibakterielle mittel |
| GB9521508D0 (en) * | 1995-10-20 | 1995-12-20 | Zeneca Ltd | Chemical compounds |
| JP2000516245A (ja) * | 1996-08-21 | 2000-12-05 | ファルマシア・アンド・アップジョン・カンパニー | 抗菌剤として有用なイソオキサゾリン誘導体類 |
-
1999
- 1999-08-19 TW TW88114208A patent/TW572757B/zh active
- 1999-08-23 NZ NZ509867A patent/NZ509867A/en unknown
- 1999-08-23 CN CN99809894A patent/CN1314813A/zh active Pending
- 1999-08-23 EP EP99945157A patent/EP1107756A4/fr not_active Withdrawn
- 1999-08-23 CA CA002341271A patent/CA2341271A1/fr not_active Abandoned
- 1999-08-23 CZ CZ2001669A patent/CZ2001669A3/cs unknown
- 1999-08-23 PL PL99346267A patent/PL346267A1/xx not_active Application Discontinuation
- 1999-08-23 CO CO99053191A patent/CO5160266A1/es unknown
- 1999-08-23 ID IDW20010439A patent/ID27690A/id unknown
- 1999-08-23 JP JP2000565887A patent/JP2002523369A/ja active Pending
- 1999-08-23 TR TR2001/00672T patent/TR200100672T2/xx unknown
- 1999-08-23 WO PCT/US1999/019265 patent/WO2000010566A1/fr not_active Application Discontinuation
- 1999-08-23 IL IL14154299A patent/IL141542A0/xx unknown
- 1999-08-23 AU AU57833/99A patent/AU748750B2/en not_active Ceased
- 1999-08-23 KR KR1020017002377A patent/KR20010072945A/ko not_active Application Discontinuation
- 1999-08-23 HU HU0103433A patent/HUP0103433A3/hu unknown
- 1999-08-23 BR BR9913225-7A patent/BR9913225A/pt not_active IP Right Cessation
- 1999-08-24 AR ARP990104229A patent/AR020250A1/es not_active Application Discontinuation
- 1999-08-24 UY UY25677A patent/UY25677A1/es unknown
- 1999-08-24 PE PE1999000853A patent/PE20001063A1/es not_active Application Discontinuation
-
2001
- 2001-02-22 ZA ZA200101505A patent/ZA200101505B/en unknown
- 2001-02-23 NO NO20010916A patent/NO20010916L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| JP2002523369A (ja) | 2002-07-30 |
| CA2341271A1 (fr) | 2000-03-02 |
| AU748750B2 (en) | 2002-06-13 |
| HUP0103433A2 (hu) | 2002-01-28 |
| AR020250A1 (es) | 2002-05-02 |
| CN1314813A (zh) | 2001-09-26 |
| ID27690A (id) | 2001-04-19 |
| UY25677A1 (es) | 2001-08-27 |
| TR200100672T2 (tr) | 2001-07-23 |
| AU5783399A (en) | 2000-03-14 |
| BR9913225A (pt) | 2001-05-22 |
| ZA200101505B (en) | 2002-02-22 |
| IL141542A0 (en) | 2002-03-10 |
| NO20010916D0 (no) | 2001-02-23 |
| KR20010072945A (ko) | 2001-07-31 |
| TW572757B (en) | 2004-01-21 |
| NO20010916L (no) | 2001-04-10 |
| EP1107756A4 (fr) | 2003-02-26 |
| PE20001063A1 (es) | 2000-12-24 |
| PL346267A1 (en) | 2002-01-28 |
| WO2000010566A1 (fr) | 2000-03-02 |
| CO5160266A1 (es) | 2002-05-30 |
| NZ509867A (en) | 2003-08-29 |
| EP1107756A1 (fr) | 2001-06-20 |
| CZ2001669A3 (cs) | 2001-08-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD9A | Lapse of provisional protection due to non-payment of fees |