PL351312A1 - New compounds, their preparation and use - Google Patents

New compounds, their preparation and use

Info

Publication number
PL351312A1
PL351312A1 PL00351312A PL35131200A PL351312A1 PL 351312 A1 PL351312 A1 PL 351312A1 PL 00351312 A PL00351312 A PL 00351312A PL 35131200 A PL35131200 A PL 35131200A PL 351312 A1 PL351312 A1 PL 351312A1
Authority
PL
Poland
Prior art keywords
preparation
use
new compounds
compounds
new
Prior art date
Application number
PL00351312A
Inventor
Anthony Murray
Per Sauerberg
Lone Jeppesen
Ingrid Pettersson
Paul Stanley Bury
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to DKPA199900533 priority Critical
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Priority to PCT/DK2000/000190 priority patent/WO2000063153A1/en
Publication of PL351312A1 publication Critical patent/PL351312A1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulfur atoms
    • C07D213/30Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/58Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • C07C59/68Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings the oxygen atom of the ether group being bound to a non-condensed six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/734Ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/40Radicals substituted by oxygen atoms
    • C07D307/42Singly bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulfur
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulfur with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/14Radicals substituted by singly bound hetero atoms other than halogen
    • C07D333/16Radicals substituted by singly bound hetero atoms other than halogen by oxygen atoms
PL00351312A 1999-04-20 2000-04-17 New compounds, their preparation and use PL351312A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
DKPA199900533 1999-04-20
PCT/DK2000/000190 WO2000063153A1 (en) 1999-04-20 2000-04-17 New compounds, their preparation and use

Publications (1)

Publication Number Publication Date
PL351312A1 true PL351312A1 (en) 2003-04-07

Family

ID=8094620

Family Applications (1)

Application Number Title Priority Date Filing Date
PL00351312A PL351312A1 (en) 1999-04-20 2000-04-17 New compounds, their preparation and use

Country Status (15)

Country Link
EP (1) EP1171414A1 (en)
JP (1) JP2002542218A (en)
CN (1) CN1348439A (en)
AU (1) AU3958000A (en)
BR (1) BR0009864A (en)
CA (1) CA2367356A1 (en)
CZ (1) CZ20013558A3 (en)
HU (1) HU0200807A3 (en)
IL (1) IL145789D0 (en)
NO (1) NO20015113L (en)
PL (1) PL351312A1 (en)
RU (1) RU2001131111A (en)
TW (1) TW553931B (en)
WO (1) WO2000063153A1 (en)
ZA (1) ZA200107983B (en)

Families Citing this family (54)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU0204574A3 (en) * 2000-01-28 2003-08-28 Novo Nordisk As Propionic acid derivatives and their use in the treatment of diabetes and obesity, pharmaceutical compositions containing them and their preparation
US6555577B1 (en) 2000-01-28 2003-04-29 Novo Nordisk A/S Compounds, their preparation and use
WO2001066135A1 (en) 2000-03-08 2001-09-13 Novo Nordisk A/S Lowering serum lipids
EP1911462A3 (en) 2001-01-26 2011-11-30 Schering Corporation Compositions comprising a sterol absorption inhibitor
US6869967B2 (en) 2001-07-30 2005-03-22 Novo Nordisk A/S Peroxisome proliferator-activated receptor (PPAR) active vinyl carboxylic acid derivatives
US7067530B2 (en) 2001-07-30 2006-06-27 Novo Nordisk A/S Compounds, their preparation and use
MXPA04000891A (en) * 2001-07-30 2004-05-21 Novo Nordisk As Novel vinyl carboxylic acid derivatives and their use as antidiabetics etc.
JP2004536152A (en) * 2001-07-30 2004-12-02 ノボ ノルディスク アクティーゼルスカブNovo Nordisk Aktie Selsxab Novel vinyl N- (2-benzoylphenyl) -L-tyrosine derivatives and their use for antidiabetic agents and the like
JP2005503377A (en) * 2001-07-30 2005-02-03 ノボ ノルディスク アクティーゼルスカブNovo Nordisk Aktie Selsxab Novel vinyl N- (2-benzoylphenyl) -L-tyrosine derivatives and their use in antidiabetic agents, etc.
WO2003031432A1 (en) 2001-10-12 2003-04-17 Novo Nordisk A/S Substituted piperidines and their use for the treatment of diseases related to the histamine h3 receptor
PL370989A1 (en) 2001-12-21 2005-06-13 Novo Nordisk A/S Amide derivatives as gk activators
US7015345B2 (en) 2002-02-21 2006-03-21 Asahi Kasei Pharma Corporation Propionic acid derivatives
US6716842B2 (en) 2002-04-05 2004-04-06 Warner-Lambert Company, Llc Antidiabetic agents
JP4881559B2 (en) 2002-06-27 2012-02-22 ノボ・ノルデイスク・エー/エス Arylcarbonyl derivatives as therapeutic agents
RU2005109555A (en) 2002-09-05 2005-11-10 Ново Нордиск А/С (DK) New vinyl carboxylic acid derivatives and their therapeutic application
AT472526T (en) 2002-10-28 2010-07-15 High Point Pharmaceuticals Llc New compounds and their use as ppar modulators
MXPA05004405A (en) * 2002-10-28 2005-07-05 Novo Nordisk As Novel compounds useful in treating ppar mediated diseases.
CN100491316C (en) 2002-10-28 2009-05-27 高点制药有限责任公司 Novel compounds, their preparation and use
US7129268B2 (en) * 2002-10-28 2006-10-31 Novo Nordisk A/S Peroxisome proliferator activated receptor-active arylene acetic acid derivatives
US7816385B2 (en) 2002-12-20 2010-10-19 High Point Pharmaceuticals, Llc Dimeric dicarboxylic acid derivatives, their preparation and use
EP1578716A1 (en) * 2002-12-20 2005-09-28 Novo Nordisk A/S Dicarboxylic acid derivatives as ppar-agonists
WO2004101505A1 (en) 2003-05-14 2004-11-25 Novo Nordisk A/S Novel compounds for treatment of obesity
PL1667964T3 (en) 2003-09-19 2010-01-29 Janssen Pharmaceutica Nv 4-((phenoxyalkyl)thio)-phenoxyacetic acids and analogs
KR20060089874A (en) 2003-09-30 2006-08-09 노보 노르디스크 에이/에스 Novel melanocortin receptor agonists
JP4865565B2 (en) 2003-12-09 2012-02-01 ノヴォ ノルディスク アー/エス Controlling food selection using GLP-1 agonists
WO2005066145A1 (en) 2004-01-06 2005-07-21 Novo Nordisk A/S Heteroaryl-ureas and their use as glucokinase activators
JP2007536344A (en) 2004-05-04 2007-12-13 ノボ ノルディスク アクティーゼルスカブNovo Nordisk Aktie Selsxab New indole derivatives
AT486838T (en) * 2004-05-05 2010-11-15 High Point Pharmaceuticals Llc New compounds, its manufacture and use
WO2005105736A1 (en) 2004-05-05 2005-11-10 Novo Nordisk A/S Novel compounds, their preparation and use
EP1758575A1 (en) 2004-06-11 2007-03-07 Novo Nordisk A/S Counteracting drug-induced obesity using glp-1 agonists
JP4874989B2 (en) 2004-11-22 2012-02-15 ノヴォ ノルディスク アー/エス Soluble and stable insulin-containing formulation
CA2590720A1 (en) 2004-12-03 2006-06-08 Lone Jeppesen Heteroaromatic glucokinase activators
FR2882359A1 (en) * 2005-02-24 2006-08-25 Negma Lerads Soc Par Actions S New phenyl compounds are peroxisome proliferator activated receptor activators useful to treat hyperlipidemia and atherosclerosis
EP1856072A4 (en) * 2005-02-25 2009-10-21 Seoul Nat Univ Ind Foundation Thiazole derivatives as ppar delta ligands and their manufacturing process
ES2375929T3 (en) 2005-07-04 2012-03-07 High Point Pharmaceuticals, Llc Histamine receiver antagonists h3.
AU2006268589B2 (en) 2005-07-14 2011-09-29 Vtv Therapeutics Llc Urea glucokinase activators
EP1910317B1 (en) 2005-07-20 2013-07-03 Eli Lilly And Company 1-amino linked compounds
PT1951658E (en) 2005-11-17 2012-11-12 Lilly Co Eli Glucagon receptor antagonists, preparation and therapeutic uses
CN103224477A (en) 2005-12-22 2013-07-31 高点制药有限责任公司 Phenoxy acetic acids as PPAR delta activators
JP2009531376A (en) 2006-03-28 2009-09-03 ハイ ポイント ファーマシューティカルズ,リミティド ライアビリティ カンパニー Benzothiazole having histamine H3 receptor activity
BRPI0711370A2 (en) 2006-05-29 2011-11-01 High Point Pharmaceuticals Llc 3- (1,3-benzodioxol-5-yl) -6- (4-cyclopropylpiperazin-1-yl) pyridazine and its salts and solvates and their use as a histamine h3 receptor antagonist
US8022066B2 (en) 2006-11-15 2011-09-20 High Point Pharmaceuticals, Llc 2-(2-hydroxyphenyl) benzothiadiazines useful for treating obesity and diabetes
EP2097388B1 (en) 2006-11-15 2011-09-07 High Point Pharmaceuticals, LLC Novel 2-(2-hydroxyphenyl)benzimidazoles useful for treating obesity and diabetes
WO2008084044A1 (en) 2007-01-11 2008-07-17 Novo Nordisk A/S Urea glucokinase activators
US20130012432A1 (en) 2010-02-26 2013-01-10 Novo Nordisk A/S Peptides for Treatment of Obesity
BR112012021231A2 (en) 2010-02-26 2015-09-08 Basf Plant Science Co Gmbh method for enhancing plant yield, plant, construct, use of a construct, method for producing a transgenic plant, collectable parts of a plant, products derived from a plant, use of a nucleic acid and method for producing a product
CN102918055B (en) 2010-03-26 2017-03-29 诺沃—诺迪斯克有限公司 New glucagon analogs
US20130156720A1 (en) 2010-08-27 2013-06-20 Ironwood Pharmaceuticals, Inc. Compositions and methods for treating or preventing metabolic syndrome and related diseases and disorders
US10130684B2 (en) 2011-02-03 2018-11-20 Pharmedica Ltd. Oral dissolving films for insulin administration, for treating diabetes
CA2830974A1 (en) 2011-03-28 2012-10-04 Jesper F. Lau Novel glucagon analogues
CA2849673A1 (en) 2011-09-23 2013-03-28 Novo Nordisk A/S Novel glucagon analogues
SI2986313T1 (en) 2013-04-18 2019-09-30 Novo Nordisk A/S Stable, protracted glp-1/glucagon receptor co-agonists for medical use
WO2018167194A1 (en) 2017-03-15 2018-09-20 Novo Nordisk A/S Bicyclic compounds capable of binding to melanocortin 4 receptor
WO2019219714A1 (en) 2018-05-15 2019-11-21 Novo Nordisk A/S Compounds capable of binding to melanocortin 4 receptor

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1996004261A1 (en) * 1994-07-29 1996-02-15 Smithkline Beecham Plc Benzoxazoles and pryridine derivatives useful in the treatment of the type ii diabetes
GB9600464D0 (en) * 1996-01-09 1996-03-13 Smithkline Beecham Plc Novel method
GB9604242D0 (en) * 1996-02-28 1996-05-01 Glaxo Wellcome Inc Chemical compounds
ES2200248T3 (en) * 1997-09-19 2004-03-01 Ssp Co., Ltd. Derivatives of acudi fenilpropionico replaced in alfa and medicinal product containing them.
AU1198699A (en) * 1997-10-27 1999-04-23 Dr. Reddy's Research Foundation Novel heterocyclic compounds and their use in medicine, process for their reparation and pharmaceutical compositions containing them
JP2002507543A (en) * 1998-05-27 2002-03-12 ドクター・レディーズ・リサーチ・ファウンデーション Bicyclic compounds, pharmaceutical compositions containing the preparation and their
WO1999019313A1 (en) * 1997-10-27 1999-04-22 Dr. Reddy's Research Foundation Novel tricyclic compounds and their use in medicine; process for their preparation and pharmaceutical compositions containing them
EP1051403A1 (en) * 1998-01-29 2000-11-15 Dr. Reddy's Research Foundation Novel alkanoic acids and their use in medicine, process for their preparation and pharmaceutical compositions containing them
EP1073643B1 (en) * 1998-04-23 2004-12-29 Dr. Reddy's Laboratories Ltd. New heterocyclic compounds and their use in medicine, process for their preparation and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP1171414A1 (en) 2002-01-16
TW553931B (en) 2003-09-21
HU0200807A3 (en) 2003-03-28
RU2001131111A (en) 2003-08-10
WO2000063153A1 (en) 2000-10-26
CN1348439A (en) 2002-05-08
ZA200107983B (en) 2002-05-29
AU3958000A (en) 2000-11-02
NO20015113L (en) 2001-12-19
BR0009864A (en) 2002-01-08
CZ20013558A3 (en) 2002-05-15
CA2367356A1 (en) 2000-10-26
IL145789D0 (en) 2002-07-25
JP2002542218A (en) 2002-12-10
NO20015113D0 (en) 2001-10-19
HU0200807A2 (en) 2002-07-29

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Legal Events

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REFS Decisions on refusal to grant patents (taken after the publication of the particulars of the applications)