HUP0102125A2 - Levotiroxin-nátriumot tartalmazó gyógyszerészeti készítmény - Google Patents

Levotiroxin-nátriumot tartalmazó gyógyszerészeti készítmény

Info

Publication number
HUP0102125A2
HUP0102125A2 HU0102125A HUP0102125A HUP0102125A2 HU P0102125 A2 HUP0102125 A2 HU P0102125A2 HU 0102125 A HU0102125 A HU 0102125A HU P0102125 A HUP0102125 A HU P0102125A HU P0102125 A2 HUP0102125 A2 HU P0102125A2
Authority
HU
Hungary
Prior art keywords
pharmaceutical preparation
levothyroxine sodium
preparation containing
containing levothyroxine
sodium
Prior art date
Application number
HU0102125A
Other languages
English (en)
Inventor
Marion Nischwitz
Sven Schreder
Original Assignee
Merck Patent Gmbh.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh. filed Critical Merck Patent Gmbh.
Publication of HUP0102125A2 publication Critical patent/HUP0102125A2/hu
Publication of HUP0102125A3 publication Critical patent/HUP0102125A3/hu
Publication of HU228958B1 publication Critical patent/HU228958B1/hu

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2063—Proteins, e.g. gelatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
    • A61P5/16—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4 for decreasing, blocking or antagonising the activity of the thyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

A találmány tárgya gyógyszerészeti készítmény, amely levotiroxin-nátriumot, zselatint és töltőanyagokat tartalmaz, és szerves oldószer-maradéktól mentes. A találmány a készítmény előállítására szolgálóeljárást is magában foglalja. Ó
HU0102125A 1998-05-15 1999-05-05 Pharmaceutical preparation containing levothyroxine sodium and gelatine and their preparation HU228958B1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19821625A DE19821625C1 (de) 1998-05-15 1998-05-15 Pharmazeutische Zubereitung
PCT/EP1999/003087 WO1999059551A1 (de) 1998-05-15 1999-05-05 Levothyroxin natrium enthaltende pharmazeutische zubereitung

Publications (3)

Publication Number Publication Date
HUP0102125A2 true HUP0102125A2 (hu) 2001-11-28
HUP0102125A3 HUP0102125A3 (en) 2001-12-28
HU228958B1 HU228958B1 (en) 2013-07-29

Family

ID=7867752

Family Applications (1)

Application Number Title Priority Date Filing Date
HU0102125A HU228958B1 (en) 1998-05-15 1999-05-05 Pharmaceutical preparation containing levothyroxine sodium and gelatine and their preparation

Country Status (25)

Country Link
US (2) US6646007B1 (hu)
EP (1) EP1077681B1 (hu)
JP (1) JP4709379B2 (hu)
CN (1) CN1145479C (hu)
AR (1) AR018607A1 (hu)
AT (1) ATE225651T1 (hu)
AU (1) AU742382B2 (hu)
BR (1) BRPI9910445B8 (hu)
CA (1) CA2333193A1 (hu)
CZ (1) CZ300908B6 (hu)
DE (2) DE19821625C1 (hu)
DK (1) DK1077681T3 (hu)
ES (1) ES2184452T3 (hu)
HU (1) HU228958B1 (hu)
ID (1) ID27281A (hu)
MY (1) MY120570A (hu)
NO (1) NO331655B1 (hu)
PL (1) PL194088B1 (hu)
PT (1) PT1077681E (hu)
RU (1) RU2225711C2 (hu)
SK (1) SK284155B6 (hu)
TW (1) TW561058B (hu)
UA (1) UA73474C2 (hu)
WO (1) WO1999059551A1 (hu)
ZA (1) ZA200007509B (hu)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030224047A1 (en) * 2001-02-15 2003-12-04 Franz G. Andrew Levothyroxine compositions and methods
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
ITMI20011401A1 (it) * 2001-07-02 2003-01-02 Altergon Sa Formulazioni farmaceutiche per ormoni tiroidei
US20030099699A1 (en) * 2001-11-13 2003-05-29 Hanshew Dwight D. Storage stable thyroxine active drug formulations and methods for their production
US20040152783A1 (en) * 2002-11-05 2004-08-05 Olon Lawrence Peter Controlled absorption of admixed thyroid hormone formulations
ITMI20110713A1 (it) 2011-04-29 2012-10-30 Bracco Imaging Spa Processo per la preparazione di un derivato solfatato di3,5-diiodo-o-[3-iodofenil]-l-tirosina
ITMI20022394A1 (it) 2002-11-13 2004-05-14 Bracco Spa Uso di triiodotironina 3-solfato come farmaco ad attivita' tireomimetica e relative formulazioni farmaceutiche.
GB0316206D0 (en) * 2003-07-10 2003-08-13 Glaxo Group Ltd Pharmaceutical formulation
ATE390919T1 (de) 2004-11-18 2008-04-15 Uni Pharma Kleon Tsetis Pharmaceutical Lab Sa Trockenpulver mit levothyroxin-natrium mit verabreichung über einen inhalator
GB0525461D0 (en) * 2005-12-15 2006-01-25 Archimedes Dev Ltd Pharmaceutical compositions
ITMI20062254A1 (it) * 2006-11-24 2008-05-25 Acraf Uso di un acido metossi-alcanoico dell'indazolo per preparare una composizione farmaceutca
EA027189B1 (ru) * 2012-08-20 2017-06-30 Мерк Патент Гмбх Твердый фармацевтический препарат, который содержит левотироксин
EP2932963A1 (en) 2014-04-16 2015-10-21 Uni-Pharma Kleon Tsetis Pharmaceutical Laboratories S.A. Stable pharmaceutical dosage forms comprising Levothyroxine sodium
US9682045B2 (en) 2014-11-21 2017-06-20 Cadila Healthcare Limited Stable pharmaceutical compositions of thyroid hormone drug
WO2018069805A2 (en) 2016-10-10 2018-04-19 Ftf Pharma Private Limited Method for preparation of liquid oral composition of l-thyroxin
CN109010295A (zh) * 2018-08-29 2018-12-18 北京兴源联合医药科技有限公司 一种左甲状腺素钠冻干口腔崩解片
CN115737576B (zh) * 2022-11-14 2024-05-07 山东创新药物研发有限公司 一种左甲状腺素钠片剂及其制备方法

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR6191M (hu) * 1966-02-18 1968-07-22
US3808332A (en) * 1969-01-27 1974-04-30 Armour Pharma Pharmaceutical compositions containing the reaction product of a tertiary phosphine with thyroxine
US3621098A (en) 1969-03-17 1971-11-16 Geigy Chem Corp HYPOTENSIVE METHODS AND COMPOSITIONS UTILIZING HEXAHYDROBENZO{8 b{9 {0 QUINOLIZINES
US3621096A (en) * 1969-04-03 1971-11-16 Univ North Carolina Antidepressant method and composition for same comprising a tricyclic antidepressant and a thyroid hormone
DE2126533A1 (de) * 1971-05-28 1972-12-14 Merck Patent Gmbh, 6100 Darmstadt Verfahren zur Herstellung pharma zeutischer Zubereitungen
HUT67319A (en) * 1991-08-30 1995-03-28 Life Medical Sciences Inc Compositions for treating wounds
US5225204A (en) 1991-11-05 1993-07-06 Chen Jivn Ren Stable dosage of levothyroxine sodium and process of production
KR100337985B1 (ko) * 1993-06-14 2002-11-23 얀센 파마슈티카 엔.브이. 아스테미졸및슈도에페드린의서방성필름-코팅정제
GB9325644D0 (en) * 1993-12-15 1994-02-16 Smithkline Beecham Plc Novel formulation
US5738875A (en) * 1994-10-28 1998-04-14 R.P. Scherer Corporation Process for preparing solid pharmaceutical dosage forms
SE9500897D0 (sv) * 1995-03-14 1995-03-14 Astra Ab The pharmacological use of certain cystine derivatives
CN1126589A (zh) 1995-06-09 1996-07-17 中国科学院成都有机化学研究所 一种激素缓释微囊注射剂及其制备方法
DE19541128C2 (de) * 1995-10-27 1997-11-27 Henning Berlin Gmbh & Co Stabilisierte schilddrüsenhormonhaltige Arzneimittel
ATE271863T1 (de) * 1995-11-14 2004-08-15 Abbott Gmbh & Co Kg Schilddrüsenhormone enthaltende stabilisierte arzneimittel und verfahren
HUT75956A (en) * 1995-11-29 1997-05-28 Cyclolab Pharmaceutical composition containing thyroxine
US20010039335A1 (en) * 1997-04-10 2001-11-08 Kenneth Jacobs Secreted proteins and polynucleotides encoding them
FR2772615B1 (fr) * 1997-12-23 2002-06-14 Lipha Comprime multicouche pour la liberation instantanee puis prolongee de substances actives
DE19830246A1 (de) * 1998-07-07 2000-01-13 Merck Patent Gmbh Pharmazeutische Zubereitung

Also Published As

Publication number Publication date
AU742382B2 (en) 2002-01-03
US8008349B2 (en) 2011-08-30
ZA200007509B (en) 2002-06-14
DK1077681T3 (da) 2002-12-30
NO20005758L (no) 2000-11-14
RU2225711C2 (ru) 2004-03-20
CN1301148A (zh) 2001-06-27
CA2333193A1 (en) 1999-11-25
SK284155B6 (sk) 2004-10-05
BRPI9910445B8 (pt) 2021-05-25
BRPI9910445B1 (pt) 2017-05-09
ID27281A (id) 2001-03-22
NO331655B1 (no) 2012-02-13
CN1145479C (zh) 2004-04-14
JP2002515421A (ja) 2002-05-28
UA73474C2 (uk) 2005-08-15
DE59903028D1 (de) 2002-11-14
CZ300908B6 (cs) 2009-09-09
ATE225651T1 (de) 2002-10-15
DE19821625C1 (de) 2000-01-05
ES2184452T3 (es) 2003-04-01
NO20005758D0 (no) 2000-11-14
BR9910445A (pt) 2001-01-02
AU3932199A (en) 1999-12-06
WO1999059551A1 (de) 1999-11-25
PL346395A1 (en) 2002-02-11
PT1077681E (pt) 2003-02-28
CZ20004201A3 (cs) 2001-03-14
US20040063611A1 (en) 2004-04-01
PL194088B1 (pl) 2007-04-30
JP4709379B2 (ja) 2011-06-22
EP1077681A1 (de) 2001-02-28
SK16892000A3 (sk) 2001-04-09
US6646007B1 (en) 2003-11-11
HU228958B1 (en) 2013-07-29
TW561058B (en) 2003-11-11
EP1077681B1 (de) 2002-10-09
MY120570A (en) 2005-11-30
HUP0102125A3 (en) 2001-12-28
AR018607A1 (es) 2001-11-28

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