HUE060282T2 - Béta-laktamáz gátló vegyületek - Google Patents
Béta-laktamáz gátló vegyületekInfo
- Publication number
- HUE060282T2 HUE060282T2 HUE17784063A HUE17784063A HUE060282T2 HU E060282 T2 HUE060282 T2 HU E060282T2 HU E17784063 A HUE17784063 A HU E17784063A HU E17784063 A HUE17784063 A HU E17784063A HU E060282 T2 HUE060282 T2 HU E060282T2
- Authority
- HU
- Hungary
- Prior art keywords
- beta
- inhibitory compounds
- lactamase inhibitory
- lactamase
- compounds
- Prior art date
Links
- 108090000204 Dipeptidase 1 Proteins 0.000 title 1
- 102000006635 beta-lactamase Human genes 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 230000002401 inhibitory effect Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D211/72—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D211/78—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- A61K31/546—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine containing further heterocyclic rings, e.g. cephalothin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B43/00—Formation or introduction of functional groups containing nitrogen
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0834—Compounds having one or more O-Si linkage
- C07F7/0892—Compounds with a Si-O-N linkage
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201662395464P | 2016-09-16 | 2016-09-16 | |
| US201762456423P | 2017-02-08 | 2017-02-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HUE060282T2 true HUE060282T2 (hu) | 2023-02-28 |
Family
ID=60083416
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HUE17784063A HUE060282T2 (hu) | 2016-09-16 | 2017-09-15 | Béta-laktamáz gátló vegyületek |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US10800778B2 (OSRAM) |
| EP (1) | EP3512851B1 (OSRAM) |
| JP (2) | JP6997178B2 (OSRAM) |
| KR (2) | KR102537340B1 (OSRAM) |
| CN (2) | CN109715630B (OSRAM) |
| AU (1) | AU2017325863B2 (OSRAM) |
| CA (1) | CA3036557A1 (OSRAM) |
| DK (1) | DK3512851T3 (OSRAM) |
| ES (1) | ES2927986T3 (OSRAM) |
| HR (1) | HRP20221217T1 (OSRAM) |
| HU (1) | HUE060282T2 (OSRAM) |
| IL (2) | IL289686B2 (OSRAM) |
| LT (1) | LT3512851T (OSRAM) |
| MA (1) | MA46242A (OSRAM) |
| MX (2) | MX385507B (OSRAM) |
| PH (1) | PH12019500558B1 (OSRAM) |
| PL (1) | PL3512851T3 (OSRAM) |
| PT (1) | PT3512851T (OSRAM) |
| SG (1) | SG11201901658PA (OSRAM) |
| SI (1) | SI3512851T1 (OSRAM) |
| SM (1) | SMT202200397T1 (OSRAM) |
| TW (1) | TWI773687B (OSRAM) |
| WO (1) | WO2018053215A1 (OSRAM) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2017290060B2 (en) | 2016-06-30 | 2021-07-22 | Qpex Biopharma, Inc | Boronic acid derivatives and therapeutic uses thereof |
| WO2018053215A1 (en) * | 2016-09-16 | 2018-03-22 | Entasis Therapeutics Limited | Beta-lactamase inhibitor compounds |
| US11046694B2 (en) | 2017-05-08 | 2021-06-29 | Entasis Therapeutics, Inc. | Compounds and methods for treating bacterial infections |
| EP3781576B1 (en) | 2018-04-20 | 2024-06-12 | Qpex Biopharma, Inc. | Boronic acid derivatives and therapeutic uses thereof |
| US11905286B2 (en) | 2018-08-09 | 2024-02-20 | Antabio Sas | Diazabicyclooctanones as inhibitors of serine beta-lactamases |
| ES2960952T3 (es) | 2018-08-09 | 2024-03-07 | Antabio Sas | Diazabiciclooctanonas como inhibidores de serina beta-lactamasas |
| CN112209928B (zh) * | 2019-07-10 | 2023-02-17 | 华东理工大学 | 共价键标记丝氨酸类beta-内酰胺酶的试剂及制备和应用 |
| CN110898999A (zh) * | 2019-11-26 | 2020-03-24 | 中国矿业大学 | 一种煤焦油基煤泥浮选药剂及其制备方法 |
| CN111790439B (zh) * | 2020-07-29 | 2022-12-27 | 成都能特科技发展有限公司 | 一种手性二级胺二苯基膦芳甲酰胺双功能催化剂及其制备方法与应用 |
| EP4146650A4 (en) | 2020-09-01 | 2024-01-17 | Ningxia Academy of Agriculture and Forestry Sciences | BETA-LACTAMASE INHIBITORS AND THEIR PRODUCTION |
| KR20230167077A (ko) * | 2021-04-05 | 2023-12-07 | 큐펙스 바이오파마 인코포레이티드 | 세프티부텐 투여 요법 |
| EP4146651A4 (en) | 2021-05-07 | 2024-06-05 | Ningxia Academy of Agriculture and Forestry Sciences | SULFONYLAMIDINE SUBSTITUTED COMPOUNDS AND THEIR USE AS BETA-LACTAMASE INHIBITORS |
| US11814385B2 (en) * | 2021-06-25 | 2023-11-14 | University Of South Florida | Small molecule inhibitors targeting Clostridioides difficile sporulation |
| WO2023206580A1 (en) | 2022-04-29 | 2023-11-02 | Entasis Therapeutics Limited | Durlobactam crystalline forms |
| US20230398101A1 (en) * | 2022-06-09 | 2023-12-14 | Fleurir Abx Llc | Co-agents as Therapy Against Anaerobic Pathogens |
| CN118271319B (zh) * | 2022-12-30 | 2025-02-28 | 成都四面体药物研究有限公司 | 一种β-内酰胺酶抑制剂含脲双环化合物、其制备方法及其用途 |
| CN118772145B (zh) * | 2023-04-04 | 2025-10-10 | 上海医药工业研究院有限公司 | 一种二氮杂双环辛烯化合物的制备方法 |
| CN116693531A (zh) * | 2023-06-09 | 2023-09-05 | 河南师范大学 | 一种桥联多环内酰胺类化合物的合成方法 |
| WO2025106662A1 (en) * | 2023-11-15 | 2025-05-22 | Entasis Therapeutics, Inc. | Preparation of boronic acid intermediates useful for the preparation of compounds for treating bacterial infections |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4607041A (en) * | 1983-04-27 | 1986-08-19 | Fisons Plc | Antihypertensive 2-phenyl Hantzsch dihydropyridines |
| ES2127946T3 (es) | 1993-12-29 | 1999-05-01 | Pfizer | Antagonistas de neurocinina diazabiciclica. |
| FR2812635B1 (fr) | 2000-08-01 | 2002-10-11 | Aventis Pharma Sa | Nouveaux composes heterocycliques, preparation et utilisation comme medicaments notamment comme anti- bacteriens |
| FR2825705B1 (fr) * | 2001-06-08 | 2005-05-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens |
| FR2835186B1 (fr) | 2002-01-28 | 2006-10-20 | Aventis Pharma Sa | Nouveaux composes heterocycliques, actifs comme inhibiteurs de beta-lactamases |
| FR2848210B1 (fr) | 2002-12-06 | 2007-10-19 | Aventis Pharma Sa | Nouveaux composes heterocycliques, leur preparation et leur utilisation comme medicaments, notamment comme anti-bacteriens et inhibiteurs de beta-lactamases |
| US7439253B2 (en) | 2002-12-06 | 2008-10-21 | Novexel | Heterocyclic compounds, their preparation and their use as medicaments, in particular as antibacterials and beta-lactamase inhibitors |
| FR2914923B1 (fr) | 2007-04-12 | 2013-06-14 | Novexel | Nouveaux composes heterocycliques azotes,leur preparation et leur utilisation comme medicaments antibacteriens. |
| EP2231667B1 (en) | 2008-01-18 | 2013-09-04 | Merck Sharp & Dohme Corp. | Beta-lactamase inhibitors |
| FR2930553B1 (fr) | 2008-04-29 | 2010-05-21 | Novexel | Composes azabicycliques, leur preparation et leur utilisation comme medicaments, notamment inhibiteurs de beta-lactamases |
| EP2135959A1 (en) | 2008-06-19 | 2009-12-23 | Novexel | Use of (1R,2S,5R) 1,6-Diazabicyclo [3,2,1]octane-2-carboxamide, 7-oxo-6-(sulfooxy)-, monosodium salt as a diagnostic reagent for detecting serine beta-lactamases |
| FR2936798B1 (fr) | 2008-10-03 | 2012-09-28 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens. |
| FR2937034B1 (fr) | 2008-10-10 | 2012-11-23 | Novexel | Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens |
| FR2936951B1 (fr) | 2008-10-10 | 2010-12-03 | Novexel | Nouvelles combinaisons de composes heterocycliques azotes antibacteriens avec d'autres composes antibacteriens et leur utilisation comme medicaments |
| FR2951171A1 (fr) | 2009-10-09 | 2011-04-15 | Novexel | Nouveau sel de sodium d'un compose azabicyclique sous forme enantiomere cristallisee et nouvelles formes polymorphes et pseudopolymorphes ainsi que leur preparation |
| BR112012026926B1 (pt) * | 2010-04-20 | 2021-01-19 | Taisho Pharmaceutical Co Ltd | composto derivado de ácido hidroxâmico, e composição farmacêutica, inibidor de lpxc e agente antimicrobiano compreendendo o referido composto |
| WO2013014496A1 (en) | 2011-07-26 | 2013-01-31 | Wockhardt Limited | Pharmaceutical compositions comprising sulbactam and beta-lactamase inhibitor |
| RU2569059C2 (ru) | 2011-07-26 | 2015-11-20 | Вокхардт Лимитед | Фармацевтические композиции, содержащие бета-лактамный антибиотик, сульбактам и ингибитор бета-лактамаз |
| RU2636147C1 (ru) | 2011-08-27 | 2017-11-21 | Вокхардт Лимитед | Производные 1,6-диазабицикло[3,2,1]октан-7-она и их применение при лечении бактериальных инфекционных болезней |
| BR112013032974A2 (pt) | 2011-08-30 | 2016-09-06 | Wockhardt Ltd | "derivados de 1,6-diazabiciclo [3,2,1]-octan-7-ona, seus usos, e composições farmacêuticas". |
| MX349827B (es) | 2011-09-13 | 2017-08-14 | Wockhardt Ltd | Compuestos que contienen nitrogeno y su uso. |
| US8796257B2 (en) | 2011-12-02 | 2014-08-05 | Naeja Pharmaceutical Inc. | Bicyclic compounds and their use as antibacterial agents and β-lactamase inhibitors |
| US20150119363A1 (en) | 2012-02-15 | 2015-04-30 | Rempex Pharmaceuticals, Inc.. | Methods of treating bacterial infections |
| US8969570B2 (en) | 2012-03-30 | 2015-03-03 | Cubist Pharmaceuticals, Inc. | Beta-lactamase inhibitors |
| US8916709B2 (en) | 2012-03-30 | 2014-12-23 | Cubist Pharmaceuticals, Inc. | 1,2,4-oxadiazole and 1,2,4-thiadiazole β-lactamase inhibitors |
| US8927724B2 (en) | 2012-03-30 | 2015-01-06 | Cubist Pharmaceuticals, Inc. | Isoxazole beta-lactamase inhibitors |
| SG11201406123TA (en) | 2012-03-30 | 2014-10-30 | Cubist Pharm Inc | 1,3,4-OXADIAZOLE AND 1,3,4-THIADIAZOLE β-LACTAMASE INHIBITORS |
| AR090539A1 (es) | 2012-04-02 | 2014-11-19 | Astrazeneca Ab | COMPUESTOS INHIBIDORES DE b LACTAMASA |
| SG10201605368UA (en) | 2012-05-30 | 2016-08-30 | Meiji Seika Pharma Co Ltd | NOVEL β-LACTAMASE INHIBITOR AND PROCESS FOR PREPARING THE SAME |
| EP2961751B1 (en) | 2012-08-25 | 2018-03-21 | Wockhardt Limited | 1,6- diazabicyclo [3,2,1]octan- 7- one derivatives and their use in the treatment of bacterial infections |
| CA2889793C (en) | 2012-09-03 | 2017-09-26 | Wockhardt Limited | Antibacterial compositions |
| BR112015018360B1 (pt) | 2013-02-06 | 2022-03-22 | Pfizer Anti-Infectives Ab | Combinação de ceftazidima, ou um sal farmaceuticamente aceitável da mesma, e avibactam, ou um sal farmaceuticamente aceitável do mesmo para o tratamento de pneumonia nosocomial |
| WO2014141132A1 (en) * | 2013-03-14 | 2014-09-18 | Naeja Pharmaceutical Inc. | NEW HETEROCYCLIC COMPOUNDS AND THEIR USE AS ANTIBACTERIAL AGENTS AND β-LACTAMASE INHIBITORS |
| HRP20190580T1 (hr) * | 2014-11-17 | 2019-05-17 | Entasis Therapeutics Limited | Kombinirana terapija radi liječenja rezistentnih bakterijskih infekcija |
| KR20170132301A (ko) | 2015-03-31 | 2017-12-01 | 무타빌리스 | 신규한 헤테로사이클릭 화합물들 및 세균성 감염의 예방 또는 치료에서 그들의 용도 |
| WO2018053215A1 (en) * | 2016-09-16 | 2018-03-22 | Entasis Therapeutics Limited | Beta-lactamase inhibitor compounds |
| KR20230007830A (ko) * | 2021-07-06 | 2023-01-13 | 현대자동차주식회사 | 고강성 저선팽창 열가소성 수지 조성물 및 이를 포함하는 성형체 |
-
2017
- 2017-09-15 WO PCT/US2017/051692 patent/WO2018053215A1/en not_active Ceased
- 2017-09-15 PH PH1/2019/500558A patent/PH12019500558B1/en unknown
- 2017-09-15 PT PT177840634T patent/PT3512851T/pt unknown
- 2017-09-15 IL IL289686A patent/IL289686B2/en unknown
- 2017-09-15 SI SI201731232T patent/SI3512851T1/sl unknown
- 2017-09-15 US US16/333,900 patent/US10800778B2/en active Active
- 2017-09-15 SG SG11201901658PA patent/SG11201901658PA/en unknown
- 2017-09-15 JP JP2019515241A patent/JP6997178B2/ja active Active
- 2017-09-15 SM SM20220397T patent/SMT202200397T1/it unknown
- 2017-09-15 KR KR1020197010376A patent/KR102537340B1/ko active Active
- 2017-09-15 PL PL17784063.4T patent/PL3512851T3/pl unknown
- 2017-09-15 LT LTEPPCT/US2017/051692T patent/LT3512851T/lt unknown
- 2017-09-15 EP EP17784063.4A patent/EP3512851B1/en active Active
- 2017-09-15 MX MX2019003060A patent/MX385507B/es unknown
- 2017-09-15 HU HUE17784063A patent/HUE060282T2/hu unknown
- 2017-09-15 HR HRP20221217TT patent/HRP20221217T1/hr unknown
- 2017-09-15 KR KR1020237017457A patent/KR102667828B1/ko active Active
- 2017-09-15 CN CN201780057302.4A patent/CN109715630B/zh active Active
- 2017-09-15 MA MA046242A patent/MA46242A/fr unknown
- 2017-09-15 DK DK17784063.4T patent/DK3512851T3/da active
- 2017-09-15 ES ES17784063T patent/ES2927986T3/es active Active
- 2017-09-15 CA CA3036557A patent/CA3036557A1/en active Pending
- 2017-09-15 TW TW106131860A patent/TWI773687B/zh active
- 2017-09-15 AU AU2017325863A patent/AU2017325863B2/en active Active
- 2017-09-15 MX MX2021010077A patent/MX392515B/es unknown
- 2017-09-15 CN CN202210161577.5A patent/CN114591223B/zh active Active
-
2019
- 2019-03-11 IL IL265276A patent/IL265276B/en unknown
-
2021
- 2021-12-16 JP JP2021203942A patent/JP7281527B2/ja active Active
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| DK3597189T3 (da) | Krystallinske forbindelser | |
| EP3454846A4 (en) | CRYSTALS | |
| DK3672941T3 (da) | Pyridylpyridonforbindelser | |
| ME03735B (me) | Inhibitori beta-laktamaze | |
| DK3672962T3 (da) | Morpholinylpyridonforbindelser | |
| LT3668879T (lt) | Nauji junginiai | |
| DK3412667T3 (da) | Cokrystal | |
| DK3436047T3 (da) | Duale Ace-C-Domain-inhibitorer |