HUE054829T2 - Folyamatok a tumort infiltráló limfociták elõállítására és felhasználásuk az immunoterápiában - Google Patents
Folyamatok a tumort infiltráló limfociták elõállítására és felhasználásuk az immunoterápiábanInfo
- Publication number
- HUE054829T2 HUE054829T2 HUE18709132A HUE18709132A HUE054829T2 HU E054829 T2 HUE054829 T2 HU E054829T2 HU E18709132 A HUE18709132 A HU E18709132A HU E18709132 A HUE18709132 A HU E18709132A HU E054829 T2 HUE054829 T2 HU E054829T2
- Authority
- HU
- Hungary
- Prior art keywords
- immunotherapy
- processes
- production
- same
- tumor infiltrating
- Prior art date
Links
- 238000009169 immunotherapy Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 210000003171 tumor-infiltrating lymphocyte Anatomy 0.000 title 1
Classifications
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- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0636—T lymphocytes
- C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
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- A—HUMAN NECESSITIES
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- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/02—Preservation of living parts
- A01N1/0278—Physical preservation processes
- A01N1/0284—Temperature processes, i.e. using a designated change in temperature over time
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- A61K2239/00—Indexing codes associated with cellular immunotherapy of group A61K39/46
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- A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
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- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
- A61K31/706—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom
- A61K31/7064—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines
- A61K31/7076—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides containing six-membered rings with nitrogen as a ring hetero atom containing condensed or non-condensed pyrimidines containing purines, e.g. adenosine, adenylic acid
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- C12N5/0634—Cells from the blood or the immune system
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Biomedical Technology (AREA)
- Zoology (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Cell Biology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Mycology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Developmental Biology & Embryology (AREA)
- Virology (AREA)
- Environmental Sciences (AREA)
- Dentistry (AREA)
- Dermatology (AREA)
- Oncology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201762478506P | 2017-03-29 | 2017-03-29 | |
US201762539410P | 2017-07-31 | 2017-07-31 | |
US201762548306P | 2017-08-21 | 2017-08-21 | |
US201762554538P | 2017-09-05 | 2017-09-05 | |
US201762559374P | 2017-09-15 | 2017-09-15 | |
US201762567121P | 2017-10-02 | 2017-10-02 | |
US201762577655P | 2017-10-26 | 2017-10-26 | |
US201762582874P | 2017-11-07 | 2017-11-07 | |
US201762596374P | 2017-12-08 | 2017-12-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
HUE054829T2 true HUE054829T2 (hu) | 2021-10-28 |
Family
ID=61569356
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HUE18709132A HUE054829T2 (hu) | 2017-03-29 | 2018-01-05 | Folyamatok a tumort infiltráló limfociták elõállítására és felhasználásuk az immunoterápiában |
Country Status (32)
Country | Link |
---|---|
US (57) | US10894063B2 (hu) |
EP (6) | EP3730608A1 (hu) |
JP (5) | JP7169291B2 (hu) |
KR (2) | KR20240114787A (hu) |
CN (1) | CN110785486A (hu) |
AU (1) | AU2018243355A1 (hu) |
BR (1) | BR112019020326A2 (hu) |
CA (1) | CA3057975A1 (hu) |
CL (2) | CL2019002769A1 (hu) |
CO (1) | CO2019011995A2 (hu) |
CR (1) | CR20190487A (hu) |
CY (1) | CY1124136T1 (hu) |
DK (1) | DK3601533T3 (hu) |
EC (1) | ECSP19077884A (hu) |
ES (1) | ES2874335T3 (hu) |
HR (1) | HRP20210677T1 (hu) |
HU (1) | HUE054829T2 (hu) |
IL (2) | IL305198A (hu) |
JO (1) | JOP20190224A1 (hu) |
LT (1) | LT3601533T (hu) |
MD (1) | MD3601533T2 (hu) |
MX (2) | MX2019011768A (hu) |
PE (1) | PE20191841A1 (hu) |
PH (1) | PH12019502247A1 (hu) |
PL (1) | PL3601533T3 (hu) |
PT (1) | PT3601533T (hu) |
RS (1) | RS61863B1 (hu) |
SG (1) | SG11201908994RA (hu) |
SI (1) | SI3601533T1 (hu) |
TN (1) | TN2019000273A1 (hu) |
TW (1) | TWI799402B (hu) |
WO (1) | WO2018182817A1 (hu) |
Families Citing this family (104)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2902448C (en) | 2013-03-01 | 2023-04-18 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods of producing enriched populations of tumor reactive t cells from peripheral blood |
GB201522097D0 (en) | 2015-12-15 | 2016-01-27 | Cellular Therapeutics Ltd | Cells |
MD3532607T2 (ro) | 2016-10-26 | 2024-07-31 | Iovance Biotherapeutics Inc | Restimularea limfocitelor infiltrante în tumori crioconservate |
US11332713B2 (en) | 2016-11-16 | 2022-05-17 | KSQ Therapeutics, Inc. | Gene-regulating compositions and methods for improved immunotherapy |
US11357841B2 (en) | 2017-01-06 | 2022-06-14 | Iovance Biotherapeutics, Inc. | Expansion of tumor infiltrating lymphocytes with potassium channel agonists and therapeutic uses thereof |
GB201700621D0 (en) | 2017-01-13 | 2017-03-01 | Guest Ryan Dominic | Method,device and kit for the aseptic isolation,enrichment and stabilsation of cells from mammalian solid tissue |
AU2018234810B2 (en) | 2017-03-15 | 2023-05-11 | Pandion Operations, Inc. | Targeted immunotolerance |
US11254913B1 (en) | 2017-03-29 | 2022-02-22 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy |
JOP20190224A1 (ar) | 2017-03-29 | 2019-09-26 | Iovance Biotherapeutics Inc | عمليات من أجل إنتاج الخلايا اللمفاوية المرتشحة للأورام واستخداماتها في العلاج المناعي |
WO2018217989A1 (en) | 2017-05-24 | 2018-11-29 | Pandion Therapeutics, Inc. | Targeted immunotolerance |
EP3635097A1 (en) * | 2017-06-05 | 2020-04-15 | Iovance Biotherapeutics, Inc. | Methods of using tumor infiltrating lymphocytes in double-refractory melanoma |
SG11202004457XA (en) * | 2017-11-17 | 2020-06-29 | Iovance Biotherapeutics Inc | Til expansion from fine needle aspirates and small biopsies |
AU2018372167B2 (en) | 2017-11-21 | 2023-12-07 | The Board Of Trustees Of The Leland Stanford Junior University | Partial agonists of interleukin-2 |
CA3083118A1 (en) | 2017-11-22 | 2019-05-31 | Iovance Biotherapeutics, Inc. | Expansion of peripheral blood lymphocytes (pbls) from peripheral blood |
US10946068B2 (en) | 2017-12-06 | 2021-03-16 | Pandion Operations, Inc. | IL-2 muteins and uses thereof |
US10174092B1 (en) | 2017-12-06 | 2019-01-08 | Pandion Therapeutics, Inc. | IL-2 muteins |
US11713446B2 (en) | 2018-01-08 | 2023-08-01 | Iovance Biotherapeutics, Inc. | Processes for generating TIL products enriched for tumor antigen-specific T-cells |
BR112020018658A2 (pt) | 2018-03-15 | 2020-12-29 | KSQ Therapeutics, Inc. | Composições de regulação gênica e métodos para imu-noterapia aprimorada |
CA3093915A1 (en) | 2018-03-15 | 2019-09-19 | KSQ Therapeutics, Inc. | Gene-regulating compositions and methods for improved immunotherapy |
FI3775165T3 (fi) * | 2018-03-29 | 2024-07-01 | Iovance Biotherapeutics Inc | Prosesseja kasvaimiin infiltroituvien lymfosyyttien tuottamiseksi ja niiden käyttö immunoterapiassa |
MA52533A (fr) | 2018-04-27 | 2021-03-03 | Iovance Biotherapeutics Inc | Procédé en circuit fermé pour l'amplification et l'edition de gènes de lymphocytes d'infiltration des tumeurs et leurs utilisations en immunothérapie |
WO2019217753A1 (en) * | 2018-05-10 | 2019-11-14 | Iovance Biotherapeutics, Inc. | Processes for production of tumor infiltrating lymphocytes and uses of same in immunotherapy |
CN113412259B (zh) | 2018-10-15 | 2024-07-16 | 紐力克斯治疗公司 | 通过泛素蛋白酶体途径降解btk的双官能化合物 |
BR112021008266A2 (pt) * | 2018-11-05 | 2022-01-04 | Iovance Biotherapeutics Inc | Métodos para expandir linfócitos infiltrantes de tumor em uma população terapêutica de linfócitos infiltrantes de tumor e para tratar um sujeito com câncer, e, população terapêutica de linfócitos infiltrantes de tumor |
PE20211292A1 (es) * | 2018-11-05 | 2021-07-20 | Iovance Biotherapeutics Inc | Procesos para la produccion de linfocitos infiltrantes de tumor y usos de estos en inmunoterapia |
CN112969469A (zh) * | 2018-11-05 | 2021-06-15 | 艾欧凡斯生物治疗公司 | 抗pd-1抗体难治性nsclc患者的治疗 |
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